Señalización citoesquelética
Los inhibidores de la señalización del citoesqueleto son compuestos que interrumpen las vías de señalización que regulan el citoesqueleto, crucial para la forma celular, la motilidad, la división y el transporte intracelular. Estos inhibidores se utilizan para estudiar la dinámica de las proteínas del citoesqueleto, como la actina y la tubulina, y su papel en procesos como la migración celular, la adhesión y la metástasis del cáncer. Los inhibidores de la señalización del citoesqueleto son valiosos en la investigación sobre biología celular, cáncer y neurobiología. En CymitQuimica, ofrecemos una amplia gama de inhibidores de la señalización del citoesqueleto de alta calidad para apoyar su investigación en estas áreas.
Se han encontrado 1382 productos de "Señalización citoesquelética"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Pep2m, myristoylated acetate
<p>Pep2m, a myristoylated acetate, inhibits GluA2-NSF interaction, reducing AMPA receptor function and expression in neurons.</p>Fórmula:C65H122N18O16SPureza:99.62%Forma y color:SolidPeso molecular:1443.96Teduglutide acetate
<p>Teduglutide acetate, a GLP-2 analogue, maximizes small intestinal mucosal hypertrophy.</p>Fórmula:C166H256N44O56SPureza:97.39%Forma y color:SoildPeso molecular:3812.13Vodobatinib
CAS:<p>Vodobatinib (K-0706) is a novel 3rd generation (3G) TKI effective against wild-type and mutated BCR-ABL1 with limited off-target activity.</p>Fórmula:C27H20ClN3O2Pureza:99.06% - 99.55%Forma y color:SolidPeso molecular:453.92Decursin
CAS:<p>Decursin: potential antiepileptic, hepatoprotective, anti-cancer, anti-amnesic; affects NOX activation, PKCα/MAPK/NF-κB pathways, AChE.</p>Fórmula:C19H20O5Pureza:97.22% - 99.84%Forma y color:SolidPeso molecular:328.36Taurochenodeoxycholic acid sodium
CAS:<p>Sodium taurochenodeoxycholate: induces apoptosis, anti-inflammatory, boosts insulin, stimulates α2-cells, increases [Ca(2+)](c).</p>Fórmula:C26H44NNaO6SPureza:98.23% - 99.45%Forma y color:White To Off-White PowderPeso molecular:521.68Pimitespib
CAS:<p>Pimitespib (TAS-116) is an ATP-competitive and highly specific HSP90α/HSP90β inhibitor (Kis: 34.7 nM and 21.3 nM, respectively).</p>Fórmula:C25H26N8OPureza:99.22% - 99.49%Forma y color:SolidPeso molecular:454.53Monastrol
CAS:<p>Monastrol ((±)-Monastrol) is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.</p>Fórmula:C14H16N2O3SPureza:98.02% - 98.59%Forma y color:SolidPeso molecular:292.35Ζ-Stat
CAS:<p>ζ-Stat (NSC37044), a specific and atypical inhibitor of PKC-ζ with an IC50 of 5 μM, demonstrates the ability to inhibit proliferation and induce apoptosis in</p>Fórmula:C10H8O10S3Pureza:99.85%Forma y color:SolidPeso molecular:384.36Mitoxantrone
CAS:<p>Mitoxantrone: anthracenedione antibiotic, disrupts DNA/RNA replication, binds to topoisomerase II, less cardiotoxic than doxorubicin.</p>Fórmula:C22H28N4O6Pureza:96.29% - 98.74%Forma y color:Blue PowderPeso molecular:444.48GLPG0187
CAS:<p>GLPG0187, a broad spectrum integrin receptor antagonist, inhibits αvβ1-integrin (IC50: 1.3 nM).</p>Fórmula:C29H37N7O5SPureza:99.4% - 99.70%Forma y color:SolidPeso molecular:595.71Chelerythrine chloride
CAS:<p>Chelerythrine Chloride is a cell-permeable inhibitor of protein kinase C, competitive with respect to the phosphate acceptor and non-competitive with respect to</p>Fórmula:C21H18ClNO4Pureza:95% - 99.19%Forma y color:Yellow To Orange SolidPeso molecular:383.83Dimethylenastron
CAS:<p>Dimethylenastron, an Eg5 inhibitor, arrests cells with monopolar spindles to which all chromosomes attach in a syntelic manner.</p>Fórmula:C16H18N2O2SPureza:98.07%Forma y color:SolidPeso molecular:302.39LP-261
CAS:<p>LP-261 is a novel tubulin targeting anticancer agent that binds at the colchicine site on tubulin, inducing G2/M arrest.</p>Fórmula:C22H19N3O4SPureza:99.91%Forma y color:SolidPeso molecular:421.47VER-82576
CAS:<p>VER-82576 (NVP-BEP800), a synthetic HSP90β inhibitor (IC50: 58 nM), exhibits >70-fold selectivity against Hsp90 family members Trap-1 and Grp94.</p>Fórmula:C21H23Cl2N5O2SPureza:97.31% - 99.85%Forma y color:SolidPeso molecular:480.41Fasudil hydrochloride
CAS:<p>Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.</p>Fórmula:C14H18ClN3O2SPureza:99.54% - ≥95%Forma y color:White SolidPeso molecular:327.83T807
CAS:<p>T807 (AV-1451) is a novel tracer of tau positron emission tomography (PET).</p>Fórmula:C16H10FN3Pureza:99.72%Forma y color:SolidPeso molecular:263.27PF-562271 hydrochloride
CAS:<p>PF-562271 hydrochloride (PF-562271 HCl) is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK.</p>Fórmula:C21H20F3N7O3SHClPureza:97.08%Forma y color:SolidPeso molecular:543.95R59949
CAS:<p>R59949 is used as a Diacylglycerol kinase (DGK) inhibitor.</p>Fórmula:C28H25F2N3OSPureza:97.04%Forma y color:SolidPeso molecular:489.58PND-1186
CAS:<p>PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM).</p>Fórmula:C25H26F3N5O3Pureza:99.14% - 99.75%Forma y color:SolidPeso molecular:501.5Natalizumab
CAS:<p>Natalizumab used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease.</p>Pureza:98.00%Forma y color:LiquidPeso molecular:N/APamidronic acid
CAS:<p>Pamidronic acid Leads to Bone Necrosis via Suppression of Wnt/β-Catenin Signaling in Human Bone Marrow Mesenchymal Stem Cells</p>Fórmula:C3H11NO7P2Pureza:97.72%Forma y color:SolidPeso molecular:235.07(E)-Akt inhibitor-IV
CAS:<p>(E)-Akt inhibitor-IV ((E)-AKTIV) ((E)-AKTIV) is an inhibitor of PI3K-Akt.</p>Fórmula:C31H29IN4SPureza:99.74% - 99.9%Forma y color:SolidPeso molecular:616.56GRGDSP acetate(91037-75-1 free base)
<p>GRGDSP acetate(91037-75-1 free base) is a synthetic linear RGD peptide and is an integrin inhibitor.</p>Fórmula:C24H41N9O12Pureza:99.77%Forma y color:SolidPeso molecular:647.64GSK-923295
CAS:<p>GSK923295 is a selective allosteric inhibitor of CENP-E kinesin motor ATPase(Ki=3.2 nM).</p>Fórmula:C32H38ClN5O4Pureza:96.22% - 98.02%Forma y color:SolidPeso molecular:592.13iRGD peptide
CAS:<p>iRGD peptide: 9-amino acid cyclic compound (CRGDKGPDC), found through phage display in mice with tumors.</p>Fórmula:C35H57N13O14S2Pureza:98.77%Forma y color:SolidPeso molecular:948.04Irigenin
CAS:<p>Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the Extra</p>Fórmula:C18H16O8Pureza:99.50% - 99.85%Forma y color:SolidPeso molecular:360.31Tirofiban hydrochloride monohydrate
CAS:<p>Tirofiban（MK383） hydrochloride monohydrate is a non-peptide glycoprotein IIb/IIIa antagonist. Cost-effective and quality-assured.</p>Fórmula:C22H39ClN2O6SPureza:98.81% - >99.99%Forma y color:White SolidPeso molecular:495.07TRC051384
CAS:<p>TRC051384 is a HSP70 inducer that reduces stroke-associated neuronal damage and increases survival in a rat model of transient ischemic stroke.</p>Fórmula:C25H31N5O4Pureza:98.79%Forma y color:SolidPeso molecular:465.541,2-Dimyristoyl-sn-glycerol
CAS:<p>1,2-Dimyristoyl-sn-glycerol (1,2-DMG) is able to increase AChE activity by 35-40% at concentrations of 25 micrograms/ml in the parasite S. mansoni..</p>Fórmula:C31H60O5Pureza:99.96%Forma y color:White Powder With LumpsPeso molecular:512.81TRC051384 HCl
CAS:<p>TRC051384 is an inducer of heat shock protein Hsp70, activating heat shock factor-1 and enhancing Hsp72 expression in neurons and glial cells.</p>Fórmula:C25H32ClN5O4Pureza:97.55%Forma y color:SolidPeso molecular:502.01A-286982
CAS:<p>A 286982 blocks the LFA-1 and ICAM-1 integrin-ligand interaction.</p>Fórmula:C24H27N3O4SPureza:97.81%Forma y color:SolidPeso molecular:453.55FRAX486
CAS:<p>FRAX486 is a potent p21-activated kinase (PAK) inhibitor with IC50 values of 14, 33, 39 and 575 nM for PAK1, PAK2, PAK3 and PAK4 respectively.</p>Fórmula:C25H23Cl2FN6OPureza:98.81% - 99.52%Forma y color:SolidPeso molecular:513.39GNF-2
CAS:<p>GNF-2 is a highly selective non-ATP competitive inhibitor of Bcr-Abl.</p>Fórmula:C18H13F3N4O2Pureza:98.17% - ≥95%Forma y color:SolidPeso molecular:374.32PRE-084 hydrochloride
CAS:<p>PRE-084 hydrochloride is a selective agonist of σ1(IC50:44 nM, in the sigma receptor assay).</p>Fórmula:C19H28ClNO3Pureza:99.54%Forma y color:SolidPeso molecular:353.88CTX-0294885 hydrochloride
<p>CTX-0294885 hydrochloride inhibits 235 kinases, affects AKT family, and aids in studying kinome-related diseases.</p>Fórmula:C22H25Cl2N7OForma y color:SolidPeso molecular:474.39CW-069
CAS:<p>CW-069 (IC50=75 μM）, an allosteric selective inhibitor of microtubule motor protein HSET, exhibits remarkable specificity over KSP.</p>Fórmula:C23H21IN2O3Pureza:97.52% - 99.52%Forma y color:SolidPeso molecular:500.33PKC-θ inhibitor hcl
CAS:<p>PKC-theta inhibitor hcl is a selective PKC-θinhibitor(IC50:12 nM).</p>Fórmula:C20H26ClF3N6O3Pureza:98.93%Forma y color:SolidPeso molecular:490.91BIO-1211
CAS:<p>BIO-1211 is a more potent inhibitor of α4β1 (VLA-4, IC50 = 4 nM) over α4β7(IC50 = 2 μM).</p>Fórmula:C36H48N6O9Pureza:99.33%Forma y color:SolidPeso molecular:708.8Tetradecyltrimethylammonium bromide
CAS:<p>Tetradecyltrimethylammonium bromide (MitMAB) is a Dynamin GTPase activity inhibitor and a cationic surfactant with asymmetrical structure.</p>Fórmula:C17H38BrNPureza:99.80%Forma y color:SolidPeso molecular:336.39ZIP acetate(863987-12-6 free base)
<p>ZIP acetate inhibits PKMζ (protein kinase Mζ), affecting LTP maintenance and spatial memory, with an IC50 of 1-2.5 μM.</p>Fórmula:C92H158N30O19Pureza:94.68%Forma y color:SolidPeso molecular:1988.43α2β1 Integrin Ligand Peptide acetate
<p>α2β1 Integrin Ligand Peptide acetate (α2β1 Integrin Ligand Peptide acetate (134580-64-6)) is a potential antagonist of α2β1 integrin receptor.</p>Fórmula:C16H26N4O11Pureza:98.46%Forma y color:SolidPeso molecular:450.4NSC45586
CAS:<p>NSC45586 is a protein phosphatase PHLPP inhibitor, which is selective for PHLPP1 and PHLPP2.</p>Fórmula:C20H18N6NaO3Pureza:99.31%Forma y color:SolidPeso molecular:413.4K858 (Racemic)
CAS:<p>K858 Racemic (K858) is a selective mitotic kinesin Eg5 inhibitor which acts in an ATP-noncompetitive manner.</p>Fórmula:C13H15N3O2SPureza:>99.99%Forma y color:SolidPeso molecular:277.34GW406108X(Z/E)
CAS:<p>GW406108X(Z/E) is a mixture of different configurations of GW406108X, which is an inhibitor of Kinesin-12 and ULK1 .</p>Fórmula:C20H11Cl2NO4Pureza:98.23%Forma y color:SolidPeso molecular:400.21CTX-0294885
CAS:<p>CTX-0294885, a bisanilino pyrimidine, inhibits many kinases; used for Sepharose-based kinase capture.</p>Fórmula:C22H24ClN7OPureza:98.73% - ≥95%Forma y color:SolidPeso molecular:437.93Valecobulin
CAS:<p>Valecobulin is a potent β-tubulin polymerization inhibitor. Valecobulin is a valine prodrug of (S516) and an avascular disrupting compound.</p>Fórmula:C26H28N6O5SPureza:98%Forma y color:SolidPeso molecular:536.6SEW2871
CAS:<p>SEW 2871 is an orally available, highly selective S1P1 agonist. It activates ERK, Akt and Rac signaling pathways and induces S1P1 internalization and recycling.</p>Fórmula:C20H10F6N2OSPureza:99.96%Forma y color:White SolidPeso molecular:440.36PF-04691502
CAS:<p>PF-04691502 is a potent and selective inhibitor of PI3K and mTOR kinases with antitumor activity.</p>Fórmula:C22H27N5O4Pureza:96.27% - ≥95%Forma y color:SolidPeso molecular:425.48SU6656
CAS:<p>SU 6656 is a selective inhibitor of Src family kinases, with IC50 of 280 nM, 20 nM, 130 nM, and 170 nM for Src, Yes, Lyn, and Fyn, respectively.</p>Fórmula:C19H21N3O3SPureza:98.21% - 98.73%Forma y color:SolidPeso molecular:371.45Tau protein (592-597), Human TFA
<p>Tau protein (592-597), Human (TFA) is a peptide fragment of human Tau protein.</p>Fórmula:C36H63F3N10O11Pureza:>99.99%Forma y color:SolidPeso molecular:868.94
