Señalización citoesquelética
Los inhibidores de la señalización del citoesqueleto son compuestos que interrumpen las vías de señalización que regulan el citoesqueleto, crucial para la forma celular, la motilidad, la división y el transporte intracelular. Estos inhibidores se utilizan para estudiar la dinámica de las proteínas del citoesqueleto, como la actina y la tubulina, y su papel en procesos como la migración celular, la adhesión y la metástasis del cáncer. Los inhibidores de la señalización del citoesqueleto son valiosos en la investigación sobre biología celular, cáncer y neurobiología. En CymitQuimica, ofrecemos una amplia gama de inhibidores de la señalización del citoesqueleto de alta calidad para apoyar su investigación en estas áreas.
Se han encontrado 1381 productos de "Señalización citoesquelética"
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NSC305787
CAS:<p>NSC305787 is an ezrin inhibitor with antitumor activity, inhibits ezrin phosphorylation caused by PKCΙ, and can be used in the study of pancreatic cancer.</p>Fórmula:C25H30Cl2N2OPureza:99.40%Forma y color:SolidPeso molecular:445.42Clathrin-IN-25
CAS:<p>Clathrin-IN-25 is the most effective clathrin terminal domain-amphiphysin inhibitor reported to date.</p>Fórmula:C19H13KNO5SForma y color:SolidPeso molecular:406.47BGB659
CAS:<p>BGB659 is effective inhibitor of RAF.</p>Fórmula:C29H29F3N4O3Pureza:98%Forma y color:SolidPeso molecular:538.56HR22C16
CAS:<p>HR22C16 is an effective, selective, and cell-permeable mitotic kinesin Eg5 inhibitor.</p>Fórmula:C23H23N3O3Forma y color:SolidPeso molecular:389.45CGP60474
CAS:<p>CGP60474 is an inhibitor of VEGFR-2 (IC50 = 84 nM) and an inhibitor of ATP-competitive PKC.</p>Fórmula:C18H18ClN5OPureza:98.81%Forma y color:SolidPeso molecular:355.82DAT1
CAS:<p>DAT1 is an antimitotic and antiangiogenic that acts by binding to the colchicine binding site of tubulin.</p>Fórmula:C17H15N3O2SPureza:98%Forma y color:SolidPeso molecular:325.38Shz 1
CAS:<p>Shz 1 is a cardiogenic agent that induces phenotypic differentiation and various cardiac-specific genes including sarcomeric tropomyosin.</p>Fórmula:C13H11BrN2O3SPureza:99.57% - 99.91%Forma y color:SolidPeso molecular:355.21GSK-3008348
CAS:<p>GSK-3008348 is an antagonist of integrin alpha(v)beta6.</p>Fórmula:C29H37N5O2Pureza:99.547%Forma y color:SolidPeso molecular:487.64BNC105P
CAS:<p>BNC105P, a prodrug VDA, converts to BNC105, blocks tubulin polymerization, disrupts tumor vessels, and evades P-glycoprotein resistance.</p>Fórmula:C20H21O10PForma y color:SolidPeso molecular:452.3485YM-01 Tosylate
CAS:<p>YM-01 Tosylate, a potent antitumor agent, selectively targets cancer cells and overcoming tamoxifen resistance.</p>Fórmula:C27H27N3O4S3Forma y color:SolidPeso molecular:553.72Displurigen
CAS:<p>Displurigen is an inhibitor of ATPase activity of HSP70.</p>Fórmula:C15H10O4SPureza:98%Forma y color:SolidPeso molecular:286.3NSC47924
CAS:<p>NSC47924 is a laminin receptor (LR) inhibitor.</p>Fórmula:C18H17NO2Pureza:98%Forma y color:SolidPeso molecular:279.33ML-243
CAS:<p>inhibitor of cancer stem cells</p>Fórmula:C14H16N2OSPureza:98%Forma y color:SolidPeso molecular:260.35Ro 43-5054
CAS:<p>Ro 43-5054 is a small molecular, noncyclic peptidomimetic inhibitor.</p>Fórmula:C24H27N5O7Pureza:98%Forma y color:SolidPeso molecular:497.5AKT-IN-9
CAS:<p>AKT-IN-9, a potent AKT inhibitor, may aid breast/prostate cancer studies. See WO2021185238A1.</p>Fórmula:C24H29ClN6OForma y color:SolidPeso molecular:452.98D011-2120
CAS:<p>D011-2120: Antiviral that blocks microtubule growth, disrupts Golgi, and hinders viral egress.</p>Fórmula:C17H15NO3Pureza:98%Forma y color:SolidPeso molecular:281.31JG-48
CAS:<p>JG-48 is an inhibitor of Hsp70. JG-48 suppresses phosphorylated and total Tau in cells, endogenous Tau in neuroblastoma cells.</p>Fórmula:C20H16F3N3OS2Forma y color:SolidPeso molecular:435.49Mps-BAY2b
CAS:<p>Mps-BAY2b is a novel MPS1 inhibitor.</p>Fórmula:C20H23N5OForma y color:SolidPeso molecular:349.43PU24FCl
CAS:<p>PU24FCl is a specific inhibitor of tumor Hsp90.</p>Fórmula:C20H21ClFN5O3Forma y color:SolidPeso molecular:433.86LDN-193665
CAS:LDN-193665 is a potent inhibitor of tau kinase. It acts by targeting CDK5/p25 and GSK3β.Fórmula:C15H11FN4OSPureza:98%Forma y color:SolidPeso molecular:314.34BOP sodium
CAS:<p>BOP sodium salt is an inhibitor of alpha9beta1 and alpha4beta1 integrin.</p>Fórmula:C25H29N3NaO7SForma y color:SolidPeso molecular:538.57Mivobulin
CAS:<p>Mivobulin is an inhibitor of tubulin .</p>Fórmula:C17H19N5O2Pureza:98%Forma y color:SolidPeso molecular:325.37Hydromethylthionine HBr
CAS:<p>Hydromethylthionine (LMTM/Leucomethylene Blue) inhibits tau in Alzheimer's/frontotemporal dementia and improves brain function.</p>Fórmula:C16H21Br2N3SForma y color:SolidPeso molecular:447.233ZW4864 free base
CAS:<p>ZW4864 (free base) is an orally active and selective β catenin/B-Cell lymphoma 9 protein protein interaction ( β catenin/BCL9 PPI ) inhibitor.</p>Fórmula:C33H42N6O3Pureza:99.81%Forma y color:SolidPeso molecular:570.72Diazobenzenesulfonic acid
CAS:<p>Diazobenzenesulfonic acid, white/red crystal, inhibits myosin ATPase 13 as an allosteric desensitizer.</p>Fórmula:C6H5N2O3SPureza:98%Forma y color:SolidPeso molecular:185.18Box5
CAS:<p>Box5 blocks Wnt5a, reducing Ca2+ release and cell migration; promising for melanoma studies.</p>Fórmula:C30H50N6O13S2Forma y color:SolidPeso molecular:766.88CCT036477
CAS:<p>CCT036477 selectively inhibits Wnt/β-catenin signaling, reducing TCF/LEF transcriptional activity.</p>Fórmula:C21H18ClN3Pureza:98%Forma y color:SolidPeso molecular:347.84Acodazole hydrochloride
CAS:<p>Acodazole hydrochloride: synthetic imidazoquinoline with antineoplastic activity; disrupts DNA replication by intercalation.</p>Fórmula:C20H20ClN5OPureza:98%Forma y color:SolidPeso molecular:381.86Tubulin polymerization-IN-37
CAS:<p>Tubulin polymerization-IN-37 inhibits tubulin polymerization at the colchicine site (IC50: 2.3 μΜ), potentially aiding lymphoma research.</p>Fórmula:C19H20N2O4Forma y color:SolidPeso molecular:340.37αvβ1 integrin-IN-1 TFA (1689540-62-2 free base)
<p>αvβ1 integrin-IN-1 TFA is an effective and selective αvβ1 integrin inhibitor (IC50: 0.63 nM).</p>Fórmula:C28H35F3N6O8SPureza:98%Forma y color:SolidPeso molecular:672.67Cevipabulin
CAS:<p>Cevipabulin (TTI-237) is a microtubule-active antitumor compound and inhibits the binding of [3H] vinblastine to tubulin (IC50: 18-40 nM in the human tumor cell</p>Fórmula:C18H18ClF5N6OPureza:99.53%Forma y color:SolidPeso molecular:464.82Anticancer agent 60
CAS:<p>Anticancer agent 60 hinders HepG2 cell growth with IC50 of 4.13 μM and suppresses tumors in HepG2 mouse model.</p>Fórmula:C27H33N5O4SForma y color:SolidPeso molecular:523.65ABH Hydrochloride
CAS:<p>ABH Hydrochloride is an arginase inhibitor, it enhances both male and female sexual arousal responses.</p>Fórmula:C6H15BClNO4Forma y color:SolidPeso molecular:211.45Malonganenone A
CAS:<p>Malonganenone A is a selective plasmodial Hsp70s modulator. It also has antimalarial activity.</p>Fórmula:C26H38N4O2Forma y color:SolidPeso molecular:438.61BMS-587101
CAS:<p>BMS-587101 is a small molecule antagonist of LFA-1, which can reduce inflammation and joint destruction in the mouse model of arthritis.</p>Fórmula:C26H20Cl2N4O4SForma y color:SolidPeso molecular:555.43BMS-358233
CAS:<p>BMS-358233 is an effective LCK inhibitor with excellent cell activity against T cell proliferation.</p>Fórmula:C25H25ClN6O2SForma y color:SolidPeso molecular:509.02Acodazole
CAS:<p>Acodazole is a synthetic imidazoquinoline. It has antimicrobial and antineoplastic properties. It also has been shown to treat arrhythmias.</p>Fórmula:C20H19N5OPureza:98%Forma y color:SolidPeso molecular:345.4L 703014
CAS:<p>L 703014 is an antagonist of the fibrinogen receptor.</p>Fórmula:C24H34N4O4Pureza:98%Forma y color:SolidPeso molecular:442.55TCS 2314
CAS:<p>TCS 2314 is an orally active and selective very late antigen-4 antagonist (IC50: 4.4 nM).</p>Fórmula:C28H34N4O6Pureza:98%Forma y color:SolidPeso molecular:522.59KIF18A-IN-3
CAS:<p>KIF18A-IN-3 is a KIF18A inhibitor (IC50=61 nM) that causes significant mitotic arrest and increases the number of mitotic cells in tumor tissues.</p>Fórmula:C28H38N4O5S2Pureza:98.45%Forma y color:SolidPeso molecular:574.76Hsp90-IN-17
CAS:<p>Hsp90-IN-17 (Example 5) is an inhibitor of HSP90, applicable in researching proliferative diseases, including cancer and neurodegenerative conditions.</p>Fórmula:C21H20N4O7Forma y color:SolidPeso molecular:440.41β-glycosidase-IN-1
CAS:<p>β-glycosidase-IN-1 is a piperidine derivative, and is an inhibitor of β-glycosidase. It has hypoglycemic activity.</p>Fórmula:C13H23NO5Pureza:98%Forma y color:SolidPeso molecular:273.33O-GlcNAcase-IN-4
CAS:<p>O-GlcNAcase-IN-4, an inhibitor from patent WO2018140299A1, may aid in neurodegenerative disease research.</p>Fórmula:C16H22FN5O3SForma y color:SolidPeso molecular:383.44OXi8007
CAS:<p>OXi8007, a water-soluble prodrug for OXi8006, disrupts vasculature and exhibits strong cytotoxicity against DU-145 cancer cells.</p>Fórmula:C26H24NNa2O10PForma y color:SolidPeso molecular:587.428Tubulin inhibitor 7
CAS:<p>Tubulin inhibitor 7 is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines (tubulin polymerization (IC50: 0.52 μM), K562 cell growth (</p>Fórmula:C21H14N2O4Pureza:98%Forma y color:SolidPeso molecular:358.35Tubulin polymerization-IN-7
CAS:<p>Tubulin aggregation-IN-7 is a potent tubulin aggregation inhibitor that has shown research potential for cancer diseases.</p>Fórmula:C28H24N4O6SForma y color:SolidPeso molecular:544.58K-80003
CAS:<p>K-80003(TX-803) is a potent retinol-like X-receptor-alpha regulator that inhibits TRxrα-dependent Akt activation and tumor cell growth.</p>Fórmula:C22H21FO2Pureza:99.76%Forma y color:SolidPeso molecular:336.4PF-2771
CAS:<p>PF-2771: potent CENP-E inhibitor, IC50 of 16.1 nM, used in cancer treatment.</p>Fórmula:C29H36ClN5O4Pureza:98%Forma y color:SolidPeso molecular:554.08NC043
CAS:<p>NC043 is an inhibitor of Wnt/β-catenin signaling, it forms a covalent bond with the Cys-516 residue of CARF.</p>Fórmula:C20H26O4Pureza:98%Forma y color:SolidPeso molecular:330.42PP2A Cancerous-IN-1
CAS:<p>PP2A Cancerous-IN-1 is a potent inhibitor of CIP2A (Cancerous inhibitor of PP2A) and p-Akt that exhibits potent anti-proliferative effects.</p>Fórmula:C30H24N4O3Forma y color:SolidPeso molecular:488.54
