Señalización citoesquelética
Los inhibidores de la señalización del citoesqueleto son compuestos que interrumpen las vías de señalización que regulan el citoesqueleto, crucial para la forma celular, la motilidad, la división y el transporte intracelular. Estos inhibidores se utilizan para estudiar la dinámica de las proteínas del citoesqueleto, como la actina y la tubulina, y su papel en procesos como la migración celular, la adhesión y la metástasis del cáncer. Los inhibidores de la señalización del citoesqueleto son valiosos en la investigación sobre biología celular, cáncer y neurobiología. En CymitQuimica, ofrecemos una amplia gama de inhibidores de la señalización del citoesqueleto de alta calidad para apoyar su investigación en estas áreas.
Se han encontrado 1382 productos de "Señalización citoesquelética"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
para-Nitroblebbistatin
CAS:<p>para-Nitroblebbistatin is a non-cytotoxic, non-fluorescent, photostable, and specific inhibitor of myosin II.Cost-effective and quality-assured.</p>Fórmula:C18H15N3O4Pureza:99.09% - 99.84%Forma y color:SolidPeso molecular:337.33Rosabulin
CAS:<p>v Rosabulin (STA 5312) is an orally active microtubule inhibitor with potency.</p>Fórmula:C22H16N4O2SPureza:98.06%Forma y color:SolidPeso molecular:400.45JB062
CAS:<p>JB062 is a chemical compound acting as a nonmuscle myosin inhibitor, exhibiting IC50 values of 1.6, 5.4, and >100 μM against skeletal muscle myosin, cardiac</p>Fórmula:C19H17NO4Pureza:99.89%Forma y color:SolidPeso molecular:323.34Elarofiban
CAS:<p>Elarofiban(RWJ-53308) is a novel and orally active GPIIb/IIIa antagonist.</p>Fórmula:C22H32N4O4Pureza:98.76%Forma y color:SolidPeso molecular:416.51JB002
CAS:<p>JB002, a myosin II inhibitor, exhibits potent activity with an IC50 of ≤10 μM.</p>Fórmula:C18H15NO3Pureza:99.74%Forma y color:SoildPeso molecular:293.32LY3372689
CAS:<p>LY3372689 (Formulaic Ia) is an orally active O-GlcNAcase (OGA) enzyme inhibitor for tau protein-based disorders including Alzheimer's disease.</p>Fórmula:C16H22FN5O3SPureza:99.43% - 99.53%Forma y color:SolidPeso molecular:383.44DCPLA-ME
CAS:<p>DCPLA-ME (2-[(2-Pentylcyclopropyl)methyl]cyclopropaneoctanoic acid methyl ester) is the methyl ester form of DCPLA and can be used to treat neurodegenerative</p>Fórmula:C21H38O2Pureza:99.80%Forma y color:SolidPeso molecular:322.53CID-663143
CAS:<p>CID-663143 inhibits cancer cell growth and shows microtubule-binding activity.</p>Fórmula:C19H18N4O2SPureza:99.68% - 99.77%Forma y color:SolidPeso molecular:366.44BIRT-377
CAS:<p>BIRT-377: orally active, hinders ICAM-1/LFA-1, blocks IL-2, useful for immune research. (Ki=25.8 nM).</p>Fórmula:C18H15BrCl2N2O2Pureza:99.93%Forma y color:SolidPeso molecular:442.13Nilotinib hydrochloride
CAS:<p>Nilotinib HCl (AMN-107 HCl), an oral Bcr-Abl inhibitor, targets neuroinflammation, cognitive issues, and chronic myelogenous leukemia.</p>Fórmula:C28H23ClF3N7OPureza:>99.99%Forma y color:SolidPeso molecular:565.98TCS 2210
CAS:<p>TCS 2210 promotes neuronal differentiation in stem cells, boosting β-III tubulin and enolase markers.</p>Fórmula:C18H17N3O3Pureza:98.62%Forma y color:SolidPeso molecular:323.35SB-216
CAS:<p>SB-216, a potent anti-cancer compound, inhibits tubulin polymerization and curbs growth in various cancer cells.</p>Fórmula:C17H18N4O2Pureza:99.70%Forma y color:SolidPeso molecular:310.35AMP-PCP disodium
CAS:<p>AMP-PCP disodium is an ATP analogue with binding affinity to the N-terminal domain of Hsp90, with a Kd value of 3.8 μM.</p>Fórmula:C11H16N5Na2O12P3Pureza:99.32%Forma y color:SolidPeso molecular:549.17BMD4503-2
CAS:<p>BMD4503-2 is a competitive inhibitor of the LRP5/6-sclerostin complex that restores the activity of the Wnt/β-catenin signaling pathway cancer.</p>Fórmula:C26H21N5O3SPureza:99.18%Forma y color:SolidPeso molecular:483.54JB061
<p>JB061 is a nonmuscle myosin inhibitor, demonstrating selective inhibitory activity with IC50 values of 4.4 μM (Cardiac muscle myosin), 9.1 μM (Skeletal muscle</p>Fórmula:C19H17NO4Pureza:99.67%Forma y color:SoildPeso molecular:323.34NSC668394
CAS:<p>NSC668394 is an ezrin phosphorylation inhibitor.NSC668394 has antitumor activity and increases ezrin cleavage.NSC668394 can be used to study tumor metastasis.</p>Fórmula:C17H12Br2N2O3Pureza:99.29% - 99.29%Forma y color:SolidPeso molecular:452.1CMPF
CAS:<p>CMPF is a microtubule protein inhibitor that can be used to study tumors.</p>Fórmula:C12H16O5Pureza:99.88%Forma y color:SolidPeso molecular:240.25AZ13705339
CAS:<p>AZ13705339 is an effective inhibitor of PAK1 with an IC50 of 0.33 nM and a Kd of 0.28 nM.</p>Fórmula:C33H36FN7O3SPureza:99.77%Forma y color:SolidPeso molecular:629.75DZ2002
CAS:<p>DZ2002: Oral, reversible SAHH inhibitor (Ki=17.9 nM), low-toxicity, immunosuppressive, counters dermal fibrosis, used in autoimmune research.</p>Fórmula:C10H13N5O3Pureza:99.91%Forma y color:SolidPeso molecular:251.24JH-VIII-157-02
CAS:<p>JH-VIII-157-02 inhibits ALK, specifically EML4-ALK variants, with IC50s of 2 nM.</p>Fórmula:C28H27N5O2Pureza:99.58%Forma y color:SolidPeso molecular:465.55Arimoclomol
CAS:<p>Arimoclomol (BRX-220 free base) is a co-inducer of heat shock proteins (HSP) and can be used in studies about the treatment of amyotrophic lateral sclerosis (</p>Fórmula:C14H20ClN3O3Pureza:99.15%Forma y color:SolidPeso molecular:313.78ZINC00640089
CAS:<p>ZINC00640089: Selective LCN2 inhibitor; curbs SUM149 cell growth and AKT activity; useful for IBC research.</p>Fórmula:C20H13F3N2O2Pureza:98.41% - 99.80%Forma y color:SolidPeso molecular:370.32DM1-SMe
CAS:<p>DM1-SMe (DM1-SSMe) potently inhibits microtubules, 3-10x stronger than Maytansine with IC50s of 0.003-0.01 nM in human cancer cells.</p>Fórmula:C36H50ClN3O10S2Pureza:99.61%Forma y color:SolidPeso molecular:784.38Defactinib hydrochloride
CAS:<p>Defactinib hydrochloride (PF 04554878 hydrochloride) is a novel inhibitor of FAK.</p>Fórmula:C20H22ClF3N8O3SPureza:98.06% - 98.78%Forma y color:SolidPeso molecular:546.95PPY A
CAS:<p>PPY A is a potent inhibitor of T315l mutant and wild-type Abl kinase and inhibits the growth of Bcr-Abl T315l mutant or wild-type Bcr-Abl gene-transformed cells</p>Fórmula:C22H20N4O2Pureza:98.77%Forma y color:SolidPeso molecular:372.42Iroxanadine
CAS:<p>Iroxanadine (BRX-005) is a Novel small molecule MAPK p38 inhibitor that induces phosphorylation of p38 SAPK and induces concentration-dependent relaxation in</p>Fórmula:C14H20N4OPureza:98.04% - 99.04%Forma y color:SolidPeso molecular:260.33Tubulin inhibitor 8
CAS:<p>Tubulin inhibitor 8 blocks tubulin polymerization, stunts K562 cancer cell growth; IC50: 0.73 μM, 14 nM.</p>Fórmula:C21H14N2O3Pureza:98.51% - 99.87%Forma y color:SolidPeso molecular:342.35Elsibucol
CAS:<p>Elsibucol (AGI 1096) is a VCAM1 inhibitor for the study of organ transplant rejection.Elsibucol is a metabolically stable propanol derivative with antioxidant,</p>Fórmula:C35H54O4S2Pureza:99.73%Forma y color:SolidPeso molecular:602.93AKT-IN-6
CAS:<p>AKT-IN-6 (INCB-047775) inhibits Akt, a key signaling protein linked to type 2 diabetes and cancer.</p>Fórmula:C22H20FN5OPureza:98.68%Forma y color:SolidPeso molecular:389.43Terflavoxate
CAS:<p>Terflavoxate is a novel, orally active, semisynthetic statin microtubule inhibitor commonly used in combination with capecitabine.</p>Fórmula:C26H29NO4Pureza:98%Forma y color:SolidPeso molecular:419.51Firategrast
CAS:<p>Firategrast (SB 683699) is an orally active and specific α4β1/α4β7 integrin antagonist.Firategrast reduces the transport of lymphocytes into the central nervous</p>Fórmula:C27H27F2NO6Pureza:99.16%Forma y color:SolidPeso molecular:499.5SNX0723
CAS:<p>SNX0723 is a potent Hsp90 Inhibitor with anti-Plasmodium activity.</p>Fórmula:C22H26FN3O3Pureza:99.85%Forma y color:SolidPeso molecular:399.46Erbulozole
CAS:<p>Erbulozole (R 55104) is a synthetic microtubule inhibitor with anti-invasive activity that induces Wernicke's encephalopathy-like neurotoxicity.</p>Fórmula:C24H27N3O5SPureza:99.88%Forma y color:SolidPeso molecular:469.55Bis-T-23
CAS:<p>Bis-T-23 is a promoter of actin-dependent dynamin oligomerization, an HIV-I integrase inhibitor, and a Telstar derivative.</p>Fórmula:C23H20N4O8Pureza:96.81% - 98.13%Forma y color:SolidPeso molecular:480.43Dynapyrazole A
CAS:<p>Dynapyrazole A inhibits dynein 1 and 2 (IC50s: 2.3, 2.6 μM) and Hedgehog signaling (IC50: 1.9 μM).</p>Fórmula:C20H12ClIN4OPureza:98.01%Forma y color:SolidPeso molecular:486.69UMK57
CAS:<p>UMK57 is a CENP-Ei and MCAK enhancer, selectively promoting k-MT attachment error correction to inhibit chromosome missegregation of small molecule compounds,</p>Fórmula:C17H17N3SPureza:99.81%Forma y color:SolidPeso molecular:295.4EMT inhibitor-1
CAS:<p>EMT inhibitor-1 is an inhibitor of Hippo, Wnt signaling and TGF- macrophages (TGF-) with antitumor activity.</p>Fórmula:C12H12Cl2N2O2SPureza:99.53%Forma y color:SolidPeso molecular:319.21JG-231
CAS:<p>JG-231, a JG-98 analog, shows anticancer properties by blocking Hsp70-BAG3 interaction and hindering TNBC in MDA-MB-231 models.</p>Fórmula:C22H18BrCl2N3OS4Pureza:99.79%Forma y color:SolidPeso molecular:619.47ASN90
CAS:<p>ASN90 is a specific, orally active inhibitor of the O-GlcNAcase (OGA) enzyme, demonstrating an IC50 of 10.2 nM.</p>Fórmula:C17H21N5O3SForma y color:SolidPeso molecular:375.45AKT-IN-13
CAS:<p>AKT-IN-13 inhibits Akt1, Akt2, Akt3 (IC50: 1.6, 2.4, 0.3 nM); used in cancer research.</p>Fórmula:C24H31ClN6O2Forma y color:SolidPeso molecular:470.99ICAM-1-IN-1
CAS:<p>ICAM-1-IN-1 is a potent and selective E-selectin(IC50 = 7 nM) and ICAM-1(IC50 = 5 nM) inhibitor.</p>Fórmula:C15H11BrN2O2SPureza:99.67%Forma y color:SolidPeso molecular:363.23ATN-161
CAS:<p>ATN-161 is an integrin α5β1 binding peptide and antagonist that inhibits VEGF-induced hCECs migration and angiogenesis.</p>Fórmula:C23H35N9O8SPureza:98%Forma y color:SolidPeso molecular:597.64MAO A/HSP90-IN-2
CAS:<p>MAO A/HSP90-IN-2 (compound 4-C), a dual inhibitor of HSP90 and MAO A, exhibits IC50 values of 0.016 μM for MAO A and 4.58 μM for HSP90.</p>Fórmula:C25H31ClN2O4Pureza:98%Forma y color:SolidPeso molecular:458.98VTX-27
CAS:<p>VTX-27 is a selective inhibitor of protein kinase C θ (PKC θ) (Kis: 0.08 nM and 16 nM for PKC θ and PKC δ).</p>Fórmula:C20H24ClFN6OPureza:99.84%Forma y color:SolidPeso molecular:418.9WAY 316606 hydrochloride
CAS:<p>WAY 316606 hydrochloride is a chemical compound that serves as an inhibitor of sFRP-1 (secreted protein), which functions as an endogenous antagonist of the Wnt (secreted glycoprotein). Its affinity for sFRP-1 is measured through the FP (fluorescence polarization) binding assay, revealing an IC50 (half maximal inhibitory concentration) of 0.5 μM [1].</p>Fórmula:C18H20ClF3N2O4S2Forma y color:SolidPeso molecular:484.94CCT251455
CAS:<p>CCT251455, the mitotic kinase monopolar spindle 1 (MPS1/TTK) inhibitor, is a potent (IC50=3 nM) and specific chemical tool.</p>Fórmula:C26H26ClN7O2Pureza:99.1% - 99.1%Forma y color:SolidPeso molecular:503.98TAK 029
CAS:<p>TAK 029 is a local glycoprotein IIb/IIIa receptor inhibitor.</p>Fórmula:C19H23N5O7Forma y color:SolidPeso molecular:433.42JG-23
CAS:<p>JG-23, a 4-chloro-modified analog, effectively induces t-tau degradation and demonstrates robust metabolic stability, exhibiting an extended half-life (T1/2) of</p>Fórmula:C19H16ClN3OS2Forma y color:SolidPeso molecular:401.93Tubulin polymerization-IN-52
CAS:<p>Tubulin polymerization-IN-52 (compound SC23) effectively inhibits tubulin polymerization, exhibiting an IC50 value of 2.9 μM [1].</p>Fórmula:C21H18F3N5O3Forma y color:SolidPeso molecular:445.39Oxaline
CAS:<p>Oxaline, a fungal alkaloid derived from Penicillium oxalicum, impedes tubulin polymerization, leading to cell cycle arrest at the M phase [1] [2].</p>Fórmula:C24H25N5O4Forma y color:SolidPeso molecular:447.49
