Señalización citoesquelética
Los inhibidores de la señalización del citoesqueleto son compuestos que interrumpen las vías de señalización que regulan el citoesqueleto, crucial para la forma celular, la motilidad, la división y el transporte intracelular. Estos inhibidores se utilizan para estudiar la dinámica de las proteínas del citoesqueleto, como la actina y la tubulina, y su papel en procesos como la migración celular, la adhesión y la metástasis del cáncer. Los inhibidores de la señalización del citoesqueleto son valiosos en la investigación sobre biología celular, cáncer y neurobiología. En CymitQuimica, ofrecemos una amplia gama de inhibidores de la señalización del citoesqueleto de alta calidad para apoyar su investigación en estas áreas.
Se han encontrado 1382 productos de "Señalización citoesquelética"
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MC-Val-Cit-PAB-Ispinesib
CAS:<p>MC-Val-Cit-PAB-Ispinesib (Compound 509) is a potent Eg5 inhibitor and a click chemistry reagent [1].</p>Fórmula:C59H71ClN10O10Forma y color:SolidPeso molecular:1115.71β-Catenin modulator-2
CAS:<p>β-Catenin Modulator-2 (Compound IIa-130), which is an oxazole-thiazole derivative, serves as a potent and selective modulator of β-Catenin [1].</p>Fórmula:C20H18Cl2N2O3SForma y color:SolidPeso molecular:437.34CNS-11
CAS:<p>CNS-11, a compound that disaggregates tau fibrils, is utilized in Alzheimer's disease (AD) research [1].</p>Fórmula:C25H21N3O2Forma y color:SolidPeso molecular:395.45PTK7/β-catenin-IN-1
CAS:<p>PTK7/β-catenin-IN-1 (compound 01065) is a potent inhibitor targeting PTK7/β-catenin and p53/MDM2, with IC50 values of 8.9 μM and 56.5 μM, respectively. This compound shows promise for cancer research applications [1].</p>Fórmula:C22H16N2O2Forma y color:SolidPeso molecular:340.382BI-1950
CAS:<p>BI-1950: potent inhibitor of LFA-1, key in immune function and drug target.</p>Fórmula:C32H26Cl2FN7O3Pureza:98%Forma y color:SolidPeso molecular:646.5BX-2819
CAS:<p>BX-2819 is an Hsp90 inhibitor that exhibits potent antiproliferative activity with an IC50 of 41 nM .</p>Fórmula:C21H24N4O4SPureza:98%Forma y color:SolidPeso molecular:428.51UU-T01
CAS:<p>UU-T01 inhibits β-catenin/Tcf4 with Ki of 3.14 µM, binds β-catenin directly with KD of 0.531 µM.</p>Fórmula:C10H10N6OForma y color:SolidPeso molecular:230.23Teclistamab
CAS:<p>Teclistamab(JNJ-64007957) is a human bispecific monoclonal antibody targeting the CD3 receptor on t-cells and the BCMA for relapsed and refractory multiple myeloma.</p>Pureza:95%Forma y color:Liquidβ-Catenin modulator-5
CAS:<p>β-Catenin Modulator-5 (Compound IIa-84), an oxazole and thiazole-based compound, serves as a potent and selective modulator of β-Catenin [1].</p>Fórmula:C21H22N2O2SForma y color:SolidPeso molecular:366.48Flavokawain 1i
CAS:<p>Flavokawain 1i, a derivative of chalcones flavokawain A, flavokawain B, and flavokawain C, exhibits anticancer and antiviral properties.</p>Fórmula:C21H18O4Forma y color:SolidPeso molecular:334.37AKT-I-1
CAS:<p>AKT-I-1 is a selective and reversible inhibitor of Akt1.</p>Fórmula:C22H30N6Pureza:99.89%Forma y color:SolidPeso molecular:378.51G-5555
CAS:<p>G-5555 is a potent inhibitor of p21-activated kinase 1 (PAK1) (Kis: 3.7 nM and 11 nM for PAK1 and PAK2, respectively).</p>Fórmula:C25H25ClN6O3Pureza:99.76% - 99.84%Forma y color:SolidPeso molecular:492.96β-Catenin modulator-1
CAS:<p>β-Catenin modulator-1 (IIa-650) is a useful agent in cancer research for modulating β-Catenin [1].</p>Fórmula:C21H28N2O4SForma y color:SolidPeso molecular:404.52JNJ-26076713
CAS:<p>JNJ-26076713, an oral alpha V integrin blocker, may treat macular edema, AMD, and diabetic retinopathy.</p>Fórmula:C29H38N4O3Pureza:98%Forma y color:SolidPeso molecular:490.64β-Catenin modulator-4
CAS:<p>β-Catenin modulator-4 (compound IIa-92), encompassing oxazole and thiazole moieties, acts as a potent and selective modulator of β-Catenin [1].</p>Fórmula:C21H21ClN2O2SForma y color:SolidPeso molecular:400.92Luvixasertib hydrochloride
CAS:<p>CFI-402257 hydrochloride, a highly selective and orally bioavailable inhibitor targeting TTK/Mps1, demonstrates an in vitro IC50 value of 1.7 nM against TTK. This compound exhibits anti-cancer activity [1].</p>Fórmula:C28H31ClN6O3Forma y color:SolidPeso molecular:535.04TAS0612
CAS:<p>TAS0612, a novel oral inhibitor of RSK, AKT, and S6K, exhibits broad-spectrum antitumor activity by impeding cell growth [1].</p>Fórmula:C27H34F3N9O2Pureza:98%Forma y color:SolidPeso molecular:573.61PAK1-IN-1
CAS:<p>PAK1-IN-1: PAK1 inhibitor, IC50 9.8 nM, hinders tumor cell migration and invasion dose-dependently.</p>Fórmula:C26H20ClN5O2Forma y color:SolidPeso molecular:469.92Pivanex
CAS:<p>Pivanex, an oral HDAC inhibitor, targets metastasis, angiogenesis, reduces Bcr-Abl protein, and promotes apoptosis.</p>Fórmula:C10H18O4Pureza:≥98%Forma y color:SolidPeso molecular:202.25ALM301
CAS:<p>ALM301: oral AKT inhibitor targeting AKT1, AKT2, AKT3; blocks AKT phosphorylation, curbs cancer cell growth.</p>Fórmula:C25H25N3O3Forma y color:SolidPeso molecular:415.48Dolastatinol
CAS:<p>Dolastatinol, a synthetic analog of Dolastatin 10, serves as a potent low-nanomolar inhibitor of tubulin polymerization.</p>Fórmula:C43H70N6O7SForma y color:SolidPeso molecular:815.12αvβ1 integrin-IN-2
CAS:<p>αvβ1 integrin-IN-2 (compound 32) is a potent inhibitor of ανβ1 and α5β1 integrins, exhibiting IC50 values of 0.9 nM and 33 nM, respectively.</p>Fórmula:C29H38N4O4Pureza:98%Forma y color:SolidPeso molecular:506.64SB-267268
CAS:<p>SB-267268: αvβ3 inhibitor (IC50: 0.68 nM human, 0.29 nM mouse), blocks αvβ3/αvβ5 integrins (Ki: 0.9 nM human, 0.5 nM monkey αvβ3, 0.7 nM human αvβ5).</p>Fórmula:C22H24F3N3O4Pureza:98%Forma y color:SolidPeso molecular:451.44Valecobulin hydrochloride
CAS:<p>Valecobulin hydrochloride (CKD-516 hydrochloride) is the valine prodrug and vasoblocker of S516.Cost-effective and quality-assured.</p>Fórmula:C26H29ClN6O5SPureza:99.52%Forma y color:SolidPeso molecular:573.06CCT-271850
CAS:<p>CCT-271850 is an inhibitor of the spindle checkpoint function of Monospindle 1.</p>Fórmula:C24H29N7OPureza:98%Forma y color:SolidPeso molecular:431.53Paluratide
CAS:<p>Paluratide (LUNA18) is a reversible KRAS inhibitor oral , which inhibits cancer cell proliferation by phosphorylating ERK and AKT, RAS with (GEFs).</p>Fórmula:C73H105F5N12O12Pureza:98.70%Forma y color:SolidPeso molecular:1437.68Levocabastine
CAS:<p>Levocarbastine: 2nd-gen H1 antagonist, treats allergic conjunctivitis, selective NTS2 neurotensin inhibitor.</p>Fórmula:C26H29FN2O2Forma y color:SolidPeso molecular:420.52ER degrader 7
CAS:<p>ER degrader 7 (Compound 35t) is a selective degrader of both ERα and ERβ, and possesses activity as a tubulin polymerization inhibitor.</p>Fórmula:C33H31F4N3O5SSeForma y color:SolidPeso molecular:736.63Zaurategrast
CAS:<p>Zaurategrast is an effective and oral-effective inhibitor of the α4-integrin.</p>Fórmula:C26H25BrN4O3Pureza:98%Forma y color:SolidPeso molecular:521.41Phenamacril
CAS:<p>Phenamacril (JS39919) is acyanoacrylate fungicide, has powerful inhibition against Fusarium species, especially to Fusarium graminearum.</p>Fórmula:C12H12N2O2Pureza:99.52%Forma y color:SolidPeso molecular:216.24HSP90-IN-29
CAS:<p>HSP90-IN-29 (Compound 13), a benzoxazole derivative, serves as a potent and selective HSP-90 inhibitor, exhibiting a low IC50 value of 30 nM. This compound demonstrates significant antitumor activity [1].</p>Fórmula:C19H20ClN3O4Forma y color:SolidPeso molecular:389.83Akt-I-1,2
CAS:<p>Akt-I-1,2 is a selective inhibitor of Akt1 and Akt2.</p>Fórmula:C23H22ClN3Pureza:99.95%Forma y color:SolidPeso molecular:375.893,4',5-Trismethoxybenzophenone
CAS:<p>3,4',5-Trismethoxybenzophenone (compound 16a) is an effective inhibitor of tubulin assembly, demonstrating a half-maximal inhibitory concentration (IC 50) of 2.6 µM [1].</p>Fórmula:C16H16O4Forma y color:SolidPeso molecular:272.3GRP78-IN-2
CAS:<p>GRP78-IN-2 inhibits surface GRP78, showing anti-angiogenic and anti-cancer properties, sparing normal cells.</p>Fórmula:C29H29NO6Forma y color:SolidPeso molecular:487.54Tirofiban HCl
CAS:<p>Tirofiban HCl is an antagonist of platelet glycoprotein-IIb/IIIa receptor.</p>Fórmula:C22H37ClN2O5SPureza:98%Forma y color:SolidPeso molecular:477.06Iroxanadine sulfate
CAS:<p>Iroxanadine sulfate is a MAPK p38 inhibitor potentially for the treatment of atherosclerosis.</p>Fórmula:C14H22N4O5SForma y color:SolidPeso molecular:358.41Integrin Antagonists 27
CAS:<p>Integrin Antagonists 27 is a small molecule integrin αvβ3 antagonist. It has a binding affinity of 18 nM and as a novel anticancer agent.</p>Fórmula:C24H20N4O5Forma y color:SolidPeso molecular:444.44PAK4-IN-1
CAS:<p>PAK4-IN-1: selective, potent oral PAK4 inhibitor; stable in acid/neutral; shows strong anti-tumor in vivo.</p>Fórmula:C26H30ClN7O5Forma y color:SolidPeso molecular:556.01Porcn-IN-2
CAS:<p>Porcn-IN-2 (Example 107) is a potent Wnt pathway inhibitor, exhibiting an IC50 of 0.05 nM.</p>Fórmula:C24H17F3N6OForma y color:SolidPeso molecular:462.43αvβ6 integrin inhibitor 2
CAS:<p>αvβ6 Integrin Inhibitor 2 is a potent inhibitor of αvβ6 integrin, demonstrating an inhibition concentration (IC50) of 96.5 nM.</p>Fórmula:C21H30N4O3Pureza:98%Forma y color:SolidPeso molecular:386.49Risvodetinib
CAS:<p>Risvodetinib: potent inhibitor of protein tyrosine kinases c-Abl1, c-Abl2, and c-kit.</p>Fórmula:C33H34N8O2Forma y color:SolidPeso molecular:574.68Solitomab
CAS:<p>Solitomab (AMG 110) is a bispecific antibody targeting CD3 and EpCAM, used in uterine/ovarian carcinosarcoma research.</p>Forma y color:LiquidLitronesib
CAS:<p>Litronesib is a selective inhibitor of mitosis-specific kinesin Eg5. It also has antitumor activity.</p>Fórmula:C23H37N5O4S2Pureza:98%Forma y color:SolidPeso molecular:511.7Tubulin inhibitor 25
CAS:<p>Potent Tubulin inhibitor 25: IC50 0.98 μM, blocks HT29 cell growth, hinders cell migration & microtubule formation, anti-angiogenic.</p>Fórmula:C26H22O8Forma y color:SolidPeso molecular:462.45β-catenin-IN-6
CAS:<p>β-Catenin-IN-6 is an inhibitor of the canonical Wnt/β-catenin signaling pathway, effectively impeding the proliferation of human colorectal cancer cells and</p>Fórmula:C22H19ClN6OForma y color:SolidPeso molecular:418.88KIF18A-IN-7
CAS:<p>KIF18A-IN-7 is an orally active inhibitor targeting KIF18A, demonstrating potent inhibition with an IC50 value of 9.4 nM against the microtubule-dependent</p>Fórmula:C27H35N3O5S2Forma y color:SoildPeso molecular:545.71MAO A/HSP90-IN-1
CAS:<p>MAO A/HSP90-IN-1 (4-b) is a dual inhibitor of MAO A and HSP90, exhibiting IC50 values of 1.77 μM in glioblastoma (GBM) GL26 cells and 0.019 μM against HSP90α.</p>Fórmula:C24H29ClN2O4Pureza:98%Forma y color:SolidPeso molecular:444.95LY2780301
CAS:<p>LY2780301, an oral Akt (protein kinase B) inhibitor, may hinder cancer cell growth and trigger apoptosis by blocking the PI3K/Akt pathway.</p>Fórmula:C25H27F4N7OForma y color:SolidPeso molecular:517.52KSP-IA
CAS:<p>KSP-IA is a potent, specific, allosteric, and cell-active KSP inhibitor.</p>Fórmula:C21H22F2N2OPureza:98%Forma y color:SolidPeso molecular:356.41Lotrafiban hydrochloride
CAS:<p>Lotrafiban hydrochloride is an platelet glycoprotein IIb/IIIa blocker with oral activity.</p>Fórmula:C23H33ClN4O4Forma y color:SolidPeso molecular:464.99
