Señalización citoesquelética
Los inhibidores de la señalización del citoesqueleto son compuestos que interrumpen las vías de señalización que regulan el citoesqueleto, crucial para la forma celular, la motilidad, la división y el transporte intracelular. Estos inhibidores se utilizan para estudiar la dinámica de las proteínas del citoesqueleto, como la actina y la tubulina, y su papel en procesos como la migración celular, la adhesión y la metástasis del cáncer. Los inhibidores de la señalización del citoesqueleto son valiosos en la investigación sobre biología celular, cáncer y neurobiología. En CymitQuimica, ofrecemos una amplia gama de inhibidores de la señalización del citoesqueleto de alta calidad para apoyar su investigación en estas áreas.
Se han encontrado 1382 productos de "Señalización citoesquelética"
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SMS 121
CAS:<p>SMS 121 is a novel CD36 inhibitor that impairs fatty acid uptake and cell viability in acute myeloid leukaemia (AML) cells.</p>Fórmula:C20H21NO5Pureza:98.29%Forma y color:SoildPeso molecular:355.38MPC-0767
CAS:<p>MPC-0767, a potent, selective, and orally active hsp90 inhibitor, is the L-alanine ester prodrug of MPC-3100, exhibiting enhanced chemical stability.</p>Fórmula:C26H36BrN7O9S2Forma y color:SolidPeso molecular:734.64AT-1002
CAS:<p>AT-1002 is a tight junction regulator and absorption enhancer. It is a 6-mer synthetic peptide.</p>Fórmula:C32H53N9O7SPureza:98%Forma y color:SolidPeso molecular:707.88Echistatin TFA
<p>Echistatin TFA: a minimal RGD protein from snake venom; inhibits platelet aggregation and bone resorption; targets αIIbβ3, αvβ3, α5β1.</p>Forma y color:Odour SolidTC113
<p>TC113, a c(RGDyK)-linked Gemcitabine, targets αvβ3 integrin, entering A549 cells, and inhibits WM266.4 and A549 cell growth.</p>Fórmula:C37H50F2N12O13Forma y color:SolidPeso molecular:908.86PROTAC BCR-ABL1 ligand 1
CAS:<p>GMB-475 is a PROTAC ligand targeting BCR-ABL1 for degradation via E3 ligase recruitment.</p>Fórmula:C17H12F3N3O2Forma y color:SoildPeso molecular:347.29AS-605240 potassium
<p>AS-605240 (potassium) is an orally active PI3Kγ inhibitor with an IC50 of 8 nM and a Ki of 7.8 nM. It inhibits MCP-1 and CSF1-induced PKB phosphorylation with IC50 values of 0.181 µM and 0.550 µM, respectively. In mouse models of peritonitis induced by RANTES (CCL5) and thioglycolate, AS-605240 (potassium) reduces neutrophil recruitment, showing EC50 values of 9.1 mg/kg and 10 mg/kg. Additionally, AS-605240 (potassium) ameliorates arthritis induced by αCII-IA in mice.</p>Fórmula:C12H6KN3O2SForma y color:SolidPeso molecular:294.98178FAK-IN-7
CAS:<p>FAK-IN-7 has potential antiproliferative activity and is a FAK inhibitor.</p>Fórmula:C16H13N3OSPureza:98.18%Forma y color:SolidPeso molecular:295.36β-catenin-IN-37
CAS:<p>β-Catenin-IN-37 is a selective inhibitor of the protein-protein interaction between β-Catenin and T-cell factor (Tcf), known as β-catenin/Tcf PPI.</p>Fórmula:C13H9N9OForma y color:SolidPeso molecular:307.277Bisindolylmaleimide III
CAS:<p>Bisindolylmaleimide III is a potent and selective inhibitor of protein kinase C (PKC).Bisindolylmaleimide III selectively interacts with PKCα or ribosomal S6</p>Fórmula:C23H20N4O2Pureza:98.6%Forma y color:SolidPeso molecular:384.43Tubulin inhibitor 24
CAS:<p>Tubulin inhibitor 24 is a potent inhibitor that can inhibit tubulin polymerization.</p>Fórmula:C22H21N3O3Pureza:99.99%Forma y color:SolidPeso molecular:375.42ML 2-23
<p>ML 2-23 is a potent BCR-ABL degrader operating as a PROTAC, exhibiting selective proteasome-dependent degradation of BCR-ABL within leukemia cells [1].</p>Fórmula:C47H53BrCl2N10O7SPureza:98%Forma y color:SolidPeso molecular:1052.86Gly-Arg-Gly-Asp-Ser
CAS:<p>Gly-Arg-Gly-Asp-Ser (GRGDS) GRGDS is a cell binding protein domain derived from the cell-binding region of fibronectin.</p>Fórmula:C17H30N8O9Pureza:98%Forma y color:SolidPeso molecular:490.47PKC β pseudosubstrate
CAS:<p>Selective cell-permeable peptide inhibitor of protein kinase C (IC50 ~ 0.5 μM).</p>Fórmula:C177H294N62O38S3Pureza:98%Forma y color:SolidPeso molecular:3994.84Dihydrocephalomannine
CAS:<p>Dihydrocephalomannine is similar to paclitaxel, showing reduced cytotoxicity and tubulin binding.</p>Fórmula:C45H55NO14Pureza:98%Forma y color:SolidPeso molecular:833.9283-Phenyltoxoflavin
CAS:<p>3-Phenyltoxoflavin (Phenyltoxoflavin) is an inhibitor of HSP90 (Kd = 585 nM) with anti-cancer activity.</p>Fórmula:C13H11N5O2Pureza:99.88%Forma y color:SolidPeso molecular:269.26Zolbetuximab
CAS:<p>Zolbetuximab (IMAB362) is a monoclonal antibody targeting Claudin-18.2 for certain gastrointestinal and pancreatic cancers.</p>Pureza:95.3% (SDS-PAGE); 95.1% (SEC-HPLC) - 97%+Forma y color:LiquidPeso molecular:147.09 kDaSTX-100
<p>PY314 is a CHO-expressed humanized monoclonal antibody targeting TREM2 with antitumor activity for the study of metastatic renal cell carcinoma.</p>Pureza:97.3% (SDS-PAGE); 97.5% (SEC-HPLC) - 97.3% (SDS-PAGE); 97.5% (SEC-HPLC)Forma y color:Odour LiquidEudebeiolide B
CAS:<p>Eudebeiolide B, isolated from Salvia plebeia R.</p>Fórmula:C15H18O4Pureza:98%Forma y color:SolidPeso molecular:262.37-Epi-docetaxel
CAS:<p>7-Epi-10-oxo-docetaxel (7-Epitaxotere) is a impurity of docetaxel.</p>Fórmula:C43H53NO14Pureza:98%Forma y color:SolidPeso molecular:807.88
