Compuestos deuterados

<p>Applications Sodium Formate (13c, 99%; D, 98%) (cas# 1215684-17-5) is a useful research chemical.<br></p>

<p>Applications 4-Hydroxychlorpropham-d7 is an intermediate in the synthesis of 4-Hydroxychlorpropham-d7 Sulfate Sodium Salt (H825077). 4-Hydroxychlorpropham-d7 Sulfate Sodium Salt is derived from Isopropanol-d7 (I822752), which is a deuterated alcohol used in the study of lignite liquefaction. 4-Hydroxychlorpropham-d7 is also the labelled analogue of 4-Hydroxychlorpropham (H825078). 4-Hydroxychlorpropham is an intermediate in synthesizing 4-Hydroxychlorpropham Sulfate Sodium Salt (H825075), which is a chemical herbicide used in the protection of crops. It also maintains the ability to induce mitochondrial dysfunction in rat hepatocytes.<br>References Kuznetov, P.N. et al.: Fuel, 70, 559 (1991); EPA.: Fed. Reg., 72, 37646 (2007); Nakagawa, Y. et al.: Toxicol., 200, 123 (2004)<br></p>

<p>Applications Pentachlorothioanisole-13C6, is the labeled analogue of Pentachlorothioanisole (P238170), which can be used in the preparation of arenethiols and arenethiolates as seen in agrochemicals or fungicides.<br>References Dulik, D. et al.: Xenobiotica, 22, 325 (1992); Rakitin, O. et al.: Sci. Synth., 31a, 949 (2007);<br></p>

<p>Applications Acts on certain olfactory receptor cell types to reduce the activating or attracting effect of odor sources.Insect repellent.<br>References Boeckh, J., et al.: Pestic. Sci., 48, 359 (1996), Yap, H.H., et al.: J. Vector Ecol., 23, 62 (1998),<br></p>

<p>Applications Labelled 4-Nonyl Phenol (N650430). Used in the process for the manufacture of 5-nonyl salicylaldoxime, which is used for the selective purification and concentration of copper ions.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 2-Ethyl 13C6-toluene is a labelled aromatic standard.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications N-Butylbenzenesulfonamide, is the labeled analogue of N-Butylbenzenesulfonamide, which is a plasticizer used commercially in the polymerization of polyamide compounds.<br>References Strong M.J., et al.: Acta Neuropathologica, 81(3), 235-241 (1991);<br></p>

<p>Applications Succinic Acid-1,4-13C2 (cas# 79864-95-2) is a compound useful in organic synthesis.<br></p>

<p>Applications A labelled metabolite of Amodiaquine (A634200), an antimalarial.<br>References Bayliss, M., et al.: Xenobiotica, 29, 253 (1999), Projean, D., et al.: Drug Metab. Dispos., 31, 748 (2003), Bray, P., et al.: Mol. Microbiol., 56, 323 (2005), Xiang, H., et al.: J. Pharm. Sci., 95, 2657 (2006),<br></p>

<p>Applications Isotope labelled β-Alanine is a naturally occurring beta amino acid. β-Alanine is formed in vivo by the degradation of dihydrouracil (D449990) and carnosine. β-Alanine is also the rate-limiting precursor of carnosine, as a result supplementation with β-alanine increases the concentration of carnosine in muscles.<br></p>

<p>Stability No Data Avaialble<br>Applications 2-Chlorophenol (Ring-D4, 99%) was an analyte in a study looking to optimize ultrasonic extraction for efficient detection of polycyclic aromatic hydrocarbons (PAHs) in soil.<br>References Stankov Jovanovic, V., et al.: Anal. Lett., 50, 2491 (2017)<br></p>

<p>Applications sotope labelled m-Cresol (C781915) is one of the components that make up liquid rice hull smoke, and may contribute to its anti-inflammatory effects in mice.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications N-Acetylglycine-d5 is an isotopic analog of N-Acetyl-glycine (A178260), a derivative of Glycine (G615990). It is an intermediate used to synthesize rac 3-O-Methyl DOPA (M303805) which is an impurity of Levodopa.<br>References Tabar, et al.: Pharmacol. Biochem. Behav., 33, 139 (1989), De Souza Silva, et al.: J. Neurochem., 68, 233 (1997), Feigin, A., et al.: Neurology, 57, 2083 (2001), Perera, A., et al.: J. Labelled Comp. Radiopharm., 46, 389 (2003),<br></p>

<p>Applications Isotope labelled 1,2-Phenylenediamine, an amino substituted benzene used in the manufacture of dyes. Potential use in sensitive immunosensor for cancer biomarker.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wu, Y. et al.: Anal. Bioanal. Chem., 400, 2141 (2011); Du, D. et al.: Anal. Chem., 82, 2989 (2010);<br></p>

<p>Applications Methionine-methyl-d3 is the labeled Methionine-methyl, a useful building block.<br></p>

<p>Applications Isotope labelled Triglycidyl isocyanurate is a reagent used in the synthesis of N-Benzyl Metaxalone (B285000), which is a muscle relaxant used to relax muscles and relieve pain.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Toth, P.E., et al.: Clin. Ther., 26, 1355 (2004)<br></p>

<p>Stability Hygroscopic<br>Applications Dioxybenzone-d3 is an isotopic analog of Dioxybenzone (D486365), a compound used in sunscreen formulations to block out UVB and UVA harmful rays.<br>References Baumgartner, V. et al.: J. Planar. Chrom. Modern. TLC., 22, 19 (2009); Kunisue, T. et al.: Anal. Meth., 2, 707 (2010);<br></p>

<p>Applications 3-Fluoro-6-nitroanisole-d3 is a compound useful in organic synthesis.<br></p>

<p>Applications The microwace spectra of Dichloroacetic Acid-d1 consists of many weak absorption lines.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Van Zoeren, E., et al.: J. Mol. Struct., 97, 315-322 (1983);<br></p>

<p>Applications A deuterated metabolite of Crotonaldehyde.<br>References Gray, J.M., and Barnsley, E.A.: Xenobiotica, 1, 55 (1971),<br></p>

<p>Applications Isotope labelled Aminoacetonitrile Hydrochloride (A580055), a useful synthetic intermediate. It is a reagent used to synthesize dipeptide nitriles as reversible and potent cathepsin S inhibitors. It can also used to prepare substituted cyclic ureas as possible HIV protease inhibitors.<br>References Ward, Y., et al.: J. Med. Chem., 45, 5471 (2002); Wilkerson, W., et al.: J. Med. Chem., 40, 4079 (1997)<br></p>

<p>Applications 5-Hydroxy Propafenone Hydrochloride-d5 is a labeled analogue of 5-Hydroxy Propafenone Hydrochloride (H952450), a metabolite of Propafenone (P757500), a sodium channel blocker. Antiarrhythmic (class IC).<br>References Hege, H.G., et al.: Eur. J. Drug Metab. Pharmacokinet., 9, 41 (1984); Hollmann, M., et al.: Arzneim.-Forsch., 33, 763 (1983); Bryson, H. M., et al.:Drugs, 45, 85 (1993); Rae, A. P., et al.: Am. J. Cardiol., 82, 59N (1998)<br></p>

<p>Stability Hygroscopic<br>Applications Hydrochloride Salt of 2-Methyl-3-isothiazolone-d3, a pesticidal substituted 3-isothiazolinone.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Thierse, H., et al.: J. Immunol., 172, 1926 (2004), Nilsson, A., et al.: Chem. Res. Toxicol., 18, 308 (2005), Nitsche, J., eet al.: J. Pharm. Sci., 95, 649 (2006),<br></p>

<p>Applications Labelled Tetraglyme. It is used as a solvent.<br></p>

<p>Applications Labelled Dimethyl Phosphate (D477600). Used in the synthesis of L,L- and L,D-di-myo-inositolphosphates.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Stieglitz, K., et al.: J. Biol. Chem., 277, 22863 (2002),<br></p>

<p>Applications Isotope labelled Melamine (M208703), which forms synthetic resins with formaldehyde. It remains largely non-metabolized in male Wistar rats with 90% of the administered dose excreted in the urine (1,2) and thus acts as a non-protein nitrogen food additive found in milk (3). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br>References 1. Mast, R. et al.: Food Chem Toxicol. 1983 Dec;21(6):807-10.2. Smith, J. et al.: Toxicol Appl Pharmacol. 1994 Apr;125(2):296-308.3. Anirudhan, T. et al.: Food Chem. 2017 Jul 15;227:85-92.<br></p>

<p>Applications (±)-Fluazifop-d4 is a labeled analogue of (±)-Fluazifop (F407430), a grass-selective herbicide which inhibits acetyl-CoA carboxylase in sensitive plant species.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Walker, K.A., et. al.: Biochem. J., 254, 307 (1988); Hajslova, J., et. al.: J. Chrom., 438, 55 (1988)<br></p>

<p>Applications A labelled form of Catechol (C215175) and has been used in the characterization of surface inclusion of unidirectional molecular motors in hexagonal tris(o-phenylene)cyclotriphosphazene.<br>References Kaleta, J.; et al.: J. Am. Chem. Soc., 139, 10486 (2017).<br></p>

<p>Applications Isotope labelled Bisphenol A Bis(diphenyl phosphate) is a flame retardant. Bisphenol A Bis(diphenyl phosphate) is used in electrical wire covering and other flame resistant materials.<br>References Takeda, K. et al.: J. Appl. Polym. Sci., 64, 1175 (1997); Levchik, S.V. et al.: J. Vinyl Add. Technol., 7, 98 (2001);<br></p>

<p>Applications Labelled Endosulfan Sulfate, a pesticide used in the control and protection of plant and vegetation.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Weston, D. et al.: Env. Sci. Tech., 38, 2752 (2004); Antonious, G. et al.: Env. Tox. Chem., 16, 644 (1997);<br></p>

<p>Applications Methyl Salicylate-13C6 is an intermediate for the synthesis of Olsalazine-13C12 Sodium Salt (O586002), which is labelled Olsalazine (O586000). Dimer of Mesalazine (M258100), an anti-inflammatory drug used in the treatment of inflammatory bowel disease and ulcerative colitis.<br>References Willoughby, C.P., Gut, 23. 1081 (1982), Scand, J., et al.: Gastroenterol, 20, 607 (1985), Wadworth, A.N., et al.: Drugs, 41, 647 (1991)<br></p>

<p>Applications Palmitoyl-16,16,16-d3-L-carnitine Hydrochloride is the isotope labelled analog of Palmitoyl-L-carnitine Hydrochloride (P155050); a long-chain fatty ester of carnitine which is accumulated and released into the circulation in fatty-acid oxidation defects.<br>References Ventura, F., et al.: Clinica Chimica Acta, 281, 1 (1999); Pourfarzam, M., et al.: Clinical Chem,, 40, 2267 (1994); Schaefer, J., et al.: Pediatric Res., 37, 354 (1995)<br></p>

<p>Applications 4-tert-Butylphenol-D9 is the labelled analogue of 4-tert-Butylphenol (B694105). 4-tert-Butylphenol is a reactant in the preparation of (2-bromocyclopent-2-en-1-yl)phenols.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Speck, K., et. al.: Org. Lett., 17, 1982 (2015)<br></p>

<p>Applications iso-Propyl 4-Hydroxybenzoate-2,3,5,6-d4 (CAS# 1219798-72-7) is a useful isotopically labeled research compound.<br></p>

<p>Applications Benzene-13C6 ,is isotopically labelled benzene, an organic compound that is a natural constituent of crude oil and one of the most basic petrochemicals.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Feng, Z.X.. et al.: J. Phys. Chem. Lett. 4, 285 (2013); Pilling. M., et al.: Chem. Eng. Prog., 108, 32 (2012);<br></p>

<p>Applications 1,4-Butane-2,2,3,3-d4-diamine 2HCl (CAS# 88972-24-1) is a useful isotopically labeled research compound.<br></p>

<p>Applications Linagliptin-d3 is the isotope labelled analogue of a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes.<br>References Prabavathy, N. et al.: Int. J. Pharm. Bio. Sci., 2, 438 (2011); Deacon, C.F.: Diab. Obes. Metab., 13, 7 (2011);<br></p>

<p>Applications 1-Bromobutane-2,2-d2 (CAS# 55724-40-8) is a useful isotopically labeled research compound.<br></p>

<p>Applications Aclonifen-d5, is the labeled analogue of Aclonifen, which is used as a pesticide and herbicide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Laini, A., et al.: Sci. Total Environ., 438, 312 (2012); Fantke, P., et al.: Enviorn. Int., 49, 9 (2012);<br></p>

<p>Applications Labelled Physcion. A natural anthraquinone derivative, on the infection process of Blumeria graminis on wheat. Physcion is one of the important active ingredients of ethanol extract from the roots of Chinese rhubarb (Rheum officinale) for controlling powdery mildew.<br>References Thiericke, R., et al.: Nat. Prod. Rep.,10, 265 (1993), Lin, C., et al.: J. Nat. Prod., 58, 1934 (1995), Julia, S., et al.: J. Biotechnol., 124, 690 (2006), Wang, W., et al.: J. Antibiot., 60, 603 (2007),<br></p>

<p>Applications Cyclohexanone-d10 is the isotope labelled analog of Cyclohexanone (C987980). Cyclohexanone, is an intermediate in the synthesis of CCNU, an effective antitumor agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Farmer, P.B., et al.: J. Med. Chem., 21, 514 (1978);<br></p>

<p>Applications Labelled Hydroxyurea. An anti-neoplastic - inhibits ribonucleoside reductase and DNA replication. A potential therapy for sickle cell anemia which involves the nitrosylation of sickle cell hemoglobin. Horseradish peroxidase catalyzes nitric oxide formation from hydroxyurea in the presence of hydrogen peroxide.<br>References Ratcliffe, W., et al.: Lancet, 339, 164 (1992), Roodman, G., et al.: Cancer, 80, 1557 (1997), Horwitz, M., et al.: J. Clin. Endocrinol. Metab., 2003, 88, 1603 (2003),<br></p>

<p>Applications A labelled derivative of Dibarbituric acid.<br>References Hitchings, G.H., et al.: J. Biol. Chem., 177, 357 (1949),<br></p>

<p>Stability Very Hygroscopic<br>Applications 4-Chlorobenzenesulfonic Acid-d4 Sodium Salt is a compound useful in organic synthesis.<br></p>

<p>Applications A labelled form of Spiromesifen (S683505), which is a useful insecticide and miticide in plant breeding. Also useful in cannabis testing kits as a component of pesticide mixes (P698240).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Stability Hygroscopic<br>Applications Benzyl Alcohol (D7, 98%) (cas# 71258-23-6) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Labelled Hydrochlorothiazide (H714560). Hydrochlorothiazide is a carbonic anhydrase inhibitor as a diuretic.<br>References Piala, J.J., et al.: J. Pharmacol. Exp. Ther., 134, 273 (1961), Deppeler, H.P., et al.: Anal. Profiles Drug Subs., 10, 405 (1981),<br></p>

<p>Applications Labelled Benzylparaben. An antimicrobial agent used in cosmetic products.<br>References Gilliland, D., et al.: J. Appl. Bacteriol., 72, 258 (1992), Routledge, E., et al.: Toxicol. Appl. Pharmacol., 153, 12 (1998), Miller, C., et al.: J. Biol. Chem., 272, 32824 (1997), Nakagawa, Y., et al.: Biochem. Pharmacol., 55, 1907 (1998),<br></p>

<p>Applications Sodium DL-Lactate-2,3,3,3-d4 (60% w/w in H2O) (CAS# 344299-52-1) is a useful isotopically labeled research compound.<br></p>

<p>Applications Carbon 13 Labelled analogue of Adenosine (A280400), a purine nucleoside that plays an important role in various biochemical processes.<br>References Long, X., et al.: J. Pharmacol. Exper. Ther., 335, 781 (2010); Ham, M., et al.: J. Pharmacol. Exper. Ther., 335, 607 (2010)<br></p>

<p>Applications 4-n-Propylphenol-d12 (CAS# 352431-21-1) is a useful isotopically labeled research compound.<br></p>

<p>Applications n-Hexadecane-d34 is the labeled compound of Hexadecane(H293630). Hexadecane has been used to prepare emulsions in water. It is also used as a substrate for the bacterial production of biosurfactants.<br>References Rang, M., et al.: J. Colloid Interface Sci., 209, 179 (1999); Hills, B., et al.: Magn. Reson. Imaging, 18, 319 (2000); Noordman, W., et al.: Appl. Environ. Microbiol., 68, 4502 (2002)<br></p>

<p>Applications 4-Desacetamido-4-chloro Andarine-D4 is a labelled analogue of 4-Desacetamido-4-chloro Andarine (D289535). 4-Desacetamido-4-chloro Andarine is a Selective Androgen Receptor Modulator (SARM) that has potential use for treatment of androgen related diseases such as muscle wasting and osteoporosis. 4-Desacetamido-4-chloro Andarine also a derivative of Andarine (A637470), a non-steroidal SARM that is used by athletes to enhance performance.<br>References Jones, A., et al.: Endocrinology, 150, 385 (2009); Marhefka, C., et al.: J. Med. Chem., 47, 993 (2004); Thomas, A., et al.: Rapid Comm. Mass Spec., 24, 1124 (2010)<br></p>

<p>Applications N-Ethyl-2-hydroxysuccinimide-d5 is the isotope labelled analog of N-Ethyl-2-hydroxysuccinimide (E919180); a metabolite of N-ethyl-2-pyrollidone (NEP) which is a frequently used industrial solvent shown to be embryotoxic in animal experiments.<br>References Schindler, B.K., et al.: Anal. Chem., 84, 3787 (2012)<br></p>

<p>Applications Cyclohexanol-d12 (CAS# 66522-78-9) is a useful isotopically labeled research compound.<br></p>

<p>Applications 1,3-Diphenyl-d10-urea is labelled 1,3-Diphenyl-urea which is a cytokinin compound present in fruit and vegetables. It is metabolized by a moderate halophilic Marinobacter sp.<br>References Sørensen, S., et al.: FEMS Microbiol. Lett., 213, 199 (2002); Campillo, N., et al.: Talanta, 116, 376 (2013)<br></p>

<p>Applications n-Octadecane-d38 (CAS# 16416-31-2) is a useful isotopically labeled research compound.<br></p>

<p>Applications Glyburide-d3 (methoxy-d3) (CAS# 1219803-02-7) is a useful isotopically labeled research compound.<br></p>

<p>Applications Labelled Fenfluramine. Anorexic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Pinder, et al.: Drugs, 10, 241 (1975), Caccia, S., et al.: Eur. J. Clin. Pharmacol., 29, 221 (1985), Finner, N., et al.: Curr. Ther. Res., 38, 847 (1985),<br></p>

<p>Applications Isotope labelled 2-Bromoethanol is an widely used intermediate in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Tian, Z., et al.: Int. J. Quant. Chem., 111, 631 (2011); Thayer, F.K., et al.: Org. Syntheses., 6, (1926);<br></p>

<p>Applications Isotope labelled D-Fructose (F792500), a monosaccharide that naturally occurs in large number of fruits and plants.<br>References Shum, M., et al.: Am. J. Physiol., 304, 197 (2013); Zeng, S.S., et al.: J. Pharma. Biomed. Anal., 76, 87 (2013);<br></p>

<p>Applications Formetanate-d6, Hydrochloride (cas# 1185240-24-7) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Biochemical tool for selective reduction of disulfide bridges at low pH; reductant for redox assay.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Neuburger, M., et al.: Eur. J. Biochem., 267, 2882 (2000), Krijt, J., et al.: Clin. Chem., 47, 1821 (2001), Yen, T.-Y., et al.: J. Mass Spectrom., 37, 15 (2002),<br></p>

<p>Applications Eicosanoic-d39 Acid (CAS# 39756-32-6) is a useful isotopically labeled research compound.<br></p>

<p>Applications 1-Bromonaphthalene-d7 (cas# 37621-57-1) is a compound useful in organic synthesis.<br></p>

<p>Applications 9-Nitroanthracene-d9 (CAS# 220381-38-4) is a useful isotopically labelled research compound. It could be useful for analytical studies that involve detecting nitrated polycyclic aromatic hydrocarbons.<br>References Siegmund, B., et al.: Anal. Bioanal. Chem., 375, 175 (2003)<br></p>

<p>Applications Phenethyl Alcohol-d5 (cas# 35845-63-7) is a compound useful in organic synthesis.<br></p>

<p>Applications Isobutyric-d6 Acid is the isotope labelled analogue of Isobutyric Acid, a carboxylic acid found in vanilla. Isobutryic Acid was used as an intermediate in the synthesis of novel inhibitors of signal transducer and activators of transcription 3 signaling pathway.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zhang, M.M., et al.: Euro. J. Med. Chem., 62, 301 (2013);<br></p>

<p>Applications Trinexapac-d5, is the labeled analogue of Trinexapac (T886315), a plant growth regulator that studies have shown to have the enzymic activity of histone lysine demethylases and histone modifications during the neural stem/progenitor cell differentiation<br>References Vavilala, D. et al.: Toxicology Reports, Vol.1, P: 1152-1161 (2014);<br></p>

<p>Applications Isotope labelled Methiocarb Sulfoxide acts as a pesticide which is used in the protection of crops from insects and fungus.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wong, J. et al.: J. Agri,. Food. Chem., 58, 5897 (2010); Ghini, S. et al.: Arch. Env. Cont. Toxicol., 47, 479 (2004);<br></p>

<p>Applications Isotope labelled Oxamyl is a pesticide used in the treatment and protection of crops from parasites and insects.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Villatte, F. et al.: Pest. Biochem. Phys., 67, 95 (2000); Zapata, A. et al.: Pankey, J. et al.: Weed. Tech., 18, 698 (2004);<br></p>

<p>Applications Hexamethylbenzene-d18 (cas# 4342-40-9) is a useful research chemical.<br></p>

<p>Applications Adamantane-d16 is used in the fast catalytic hydroxylation of hydrocarbons with ruthenium porphyrins. Unlabeled adamantane derivatives have been used to treat influenza, as well as serve as NMDA receptor channel blockers for a wide range of pharmaceutical application.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wang, C. et al.: Inorg. Chem. 45, 4769 (2012); Thomas. A. et al.: J. Neurosci., 25, 3312 (2005); Deyde, V. et al.: Exp. Rev. Mol. Diag., 9, 493 (2009);<br></p>

<p>Applications Labelled Lactose Monohydrate (L114000), which is used in the synthesis of casing for various methods of oral drug delivery, including dissolving pellets, and long-lasting pellets.<br>References Kamble, M. et al.: Int. J. Pharm. Chem. Biol. Sci., 3, 55 (2013); Hiorth, M. et al.: Int. J. Pharm., 441, 544 (2013);<br></p>

<p>Applications (±)-Atropine-D3 is a racemic isotope-labeled analog of Atropine, (A794630), which is a nerve agent that occurs naturally in plants oft he nightshade family.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kujak, R., et al.: J. Pharma. Biomed. Anal., 2015<br></p>

<p>Applications Isotope labelled N-Iodoacetyltyramine (I685880) is used in iodine-125 labelling of various molecules for chemical analysis.<br>References Lin, C. et al.: Anal. Biochem., 179, 389 (1989);<br></p>

<p>Applications 2,5-Dichloroaniline-3,4,6-d3 (CAS# 783321-80-2) is a useful isotopically labeled research compound.<br></p>

<p>Stability Hygroscopic<br>Applications Ethanolamine-13C2 Hydrochloride is the labeled analogue of Ethanolamine (E676500), which is used in the preparation of various pharmaceutical compounds and inhibitors. Ethanolamine-13C2, is also a 13C-labeled lipid precursor, used for the detection of phospholipid metabolism and the synthesis of phosphatidylethanolamine in T47D human breast cancer cells.<br>References Ronen, S. M., et al.: Magnetic Resonance Med., 25, 384 (1992); Lombardo, L. et al.: J. Med. Chem., 47, 6658 (2004); Egan, T.: J. Med. Chem., 43, 283 (2000);<br></p>

<p>Applications A labelled acetylene glycol derivative. It is used in water-based coatings and has both antifoaming and surfactant properties. It is highly toxic and have been found in acrylic adhesives used for food packaging multilayers manufacturing.<br>References Schwartz, J. et al.: J. Coat. Tecnhol., 67, 21 (1995); Chinoy, N.F. et al.: Polym. Paint Colour J., 175, 438 (1985);<br></p>

<p>Applications A labelled analog of a naturally occurring purine derivative.<br>References Wetmore, D., et al.: J. Biol. Chem., 285, 30516 (2010), Jung, Y., et al.: J. Agric. Food Chem., 58, 10458 (2010), Cao, H., et al.: J. Biol. Chem., 285, 28044 (2010),<br></p>

<p>Applications Suberyl glycine-d4 is deuterium labelled Suberylglycine (S688755), which is one of the acylglycines, an important class of metabolites that have been used in the diagnosis of several inborn errors of metabolism (IEM).<br>References Costa, C., et al.: J. Pharmaceut. Biomed. Anal., 21, 1215 (2000); Garcia-Villoria, J., et al.: Clin. Biochem., 42, 2 (2009); Scalbert, A., et al.: Metabolomics, 5, 435 (2009)<br></p>

<p>Applications n-Pentacosane-d52 (CAS# 121578-13-0) is a useful isotopically labeled research compound.<br></p>

<p>Applications 2-Chloronaphthalene-d7 (CAS# 93951-84-9) is a useful isotopically labeled research compound.<br></p>

<p>Applications N-Methyl-d3-formamide (CAS# 87955-92-8) is a useful isotopically labeled research compound.<br></p>

<p>Applications Isotope labelled Tebufenozide (T013200), which is a synthetic nonsteroidal ecdysone agonist used in pesticide formulations (1) that causes premature molting; novel insect growth regulator (2,3,4) specific to lepidopteran species. Drinking water Contaminant Candidate List 3 (CCL3) as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. Jordan TB, et al.: Anal Bioanal Chem. 2009 Aug;394(8):2257-66.2. Vianna UR. Et al.: Ecotoxicology. 2009 Feb;18(2):180-6.3. Rose, G. et al. Food. Chem. 2009 Dec;117(4) pp634-6404. Wang, J. et al.: J. Agric. Food Chem. 2009 Mar 25;57(6):2162-73.<br></p>

<p>Applications 1-Butan-1,1-d2-ol is the deuterium labeled version of 1-Butanol (B690045). It can be used in the synthesis of more complex isotope labeled compounds.<br>References Sharma, Shikha, et al.: J. of Radioanaly. and Nuc. Chem., 302(1), 583-591 (2014);Hirsekorn, Kurt F., et al.: J. of the Ame. Chem. Soc., 127(13), 4809-4830 (2005)<br></p>

<p>Applications β-Cyclodextrin Deuterated is an isotope analog of β-Cyclodextrin (C987830), which is a cyclic oligosaccharide produced from starch via enzymatic conversion. β-Cyclodextrin is commonly used to produce HPLC columns allowing chiral enantiomers separation.<br>References Motoyama, A. et al.: J. Pharmac. Biomed. Anal., 28, 97 (2002); Nakamura, N. et al. Biotechnol. Bioeng., 19, 87 (1977); Riddle, L. A. et al.: J. Chrom. Sci., 45, 330 (2007);<br></p>

<p>Applications Labelled Propionic Acid, used in the synthesis of novel inhibitors of signal transducer and activator of transcription 3 signaling pathway in the potential treatment of human cancers. In addition it is used in the synthesis of morphans.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zhang, M. et al.: Eur. J. Med. Chem., 62, 301 (2013); Bradshaw, B. et al.: Org. Lett., 15, 2458 (2013);<br></p>

<p>Stability Hygroscopic, Light Sensitive<br>Applications 13C-labelled Phenol (P318000).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Uracil-15N2 can be used as a stable-isotopic standard to measure of post-replicative DNA metabolic and damage in brains of rodents. This compound can also be used for isotope tracing to determine the mechanism and stem-cell activity of 5-carboxycytosine decarboxylation.<br>References Patel, J.P., et.al., Chem. Res. Toxicol., 28, 2352-2363, (2015); Schiesser, S., et.al., Angew. Chem. Int. Ed., 51,6516-6520, (2012);<br></p>

<p>Applications 9-cis-Retinyl Stearate-d5, is the labeled analogue of 9-cis-Retinyl Stearate (R275600), a fatty acid ester of Retinol isomer, found mainly in the retina.<br>References Bridges, C.D.B., et al.: Methods Enzymol., 81, 463 (1982),<br></p>