Compuestos deuterados

Applications Isotope labelled 2,2,4-Trimethyl-1,3-pentanediol used in the synthesis of monoisobutyrate derivatives used in film forming auxilleries in paint substances.
References Li, Y. et al.: Chem. Papers, 68, 422 (2014);

Applications 5-Ethyl-3-[[(2R)-1-methyl-2-pyrrolidinyl]methyl]-1H-indole-d5 is an isotope labelled impurity of Eletriptan (E505000), a serotonin 5-HTIB/ID receptor agonist and an antimigraine agent.
References Madasu, S. B., et al.: Beilstein. J. Org. Chem., 8, 1400 (2012); Willems, E., et al.: Arch. Pharmacol., 358, 212 (1998), Napier, C., et al.: Eur. J. Pharmacol., 368, 259 (1999), Goadsby, P.J., et al.: Neurology, 54, 156 (2000)

Applications Iodoethane-2-d1 (CAS# 57460-45-4) is a useful isotopically labeled research compound.

Applications Bis(1,3-dithian-2-yl)methane-d2 (cas# 105479-87-6) is a compound useful in organic synthesis.

Applications Isotope Labelled Adipodinitrile is used in the preparation of alkyl/arylthiazolines in the efficient synthesis of bacillamide A. Also used in the preparation of arylketones via insertion of nitriles.
References Fache, F. et al.: Synth. Comm., 42, 2098 (2012); Hsieh, J. et al.: Org. Lett., 14, 1282 (2012);

Applications 2,2,3,5-Tetramethylhexanoic Acid-d3 is the isotope analog of 2,2,3,5-Tetramethylhexanoic Acid. 2,2,3,5-Tetramethylhexanoic Acid is used in analytical studies as a method to quantitatively determine the total organic acid content in aqueous coolant.
References Lynn, T.B., et al.: PCT Int. Appl., 2012:1561111 (2012)

Applications Nilvadipine-d3 is labelled Nilvadipine (N475150) which is used as an antihypertensive and antianginal.
References Gross, G.J., et al.: Gen. Pharmacol., 14, 677 (1983); Molyvdas, P.A. and Sperelakis, N.: J. Cardiovasc. Pharmacol., 8, 449 (1986); Mizuno, K., et al.: Res. Comm. Chem. Pathol. Pharmacol., 52, 3 (1986)

Applications N-Cyclopropyl-5-(thiophen-2-yl)isoxazole-3-carboxamide -d4 is labelled N-Cyclopropyl-5-(thiophen-2-yl)isoxazole-3-carboxamide (C988880) which was shown to exhibit regulatory effects towards the expression of pH sensing G protein-coupled receptor-68 and is now a new drug target for ischemic heart disease.
References Russell, J.L., et al.: ACS. Chem. Biol., 7, 1077 (2012); Schneider, J.W., et al.: ACS. Chem. Neurosci., 3, 557 (2012);

Applications Isotope labelled 1,4-Dichlorobenzene is labelled 1,4-Dichlorobenzene (D431875), a versatile building block and a small bioactive molecule, used in various organic synthesis. It is also used as disinfectant, deodorant, and pesticide.
References Fahey, D. R., et al.: Macromolecules, 24 (15), 4242 (1991); Rossberg, M., et al.: Ullmann's Encyclopedia of Industrial Chemistry, (2006);

Applications 1-(2-Furyl)ethanol-d3 is the isotope labelled analog of 1-(2-Furyl)ethanol (F865260), which is an intermediate in the synthesis of 2H-Furo[2,3-c]pyran-2-one derivatives of their germination-promoting activity.
References Singh, V., et al.: Synthetic. Commun., 40, 1280 (2010);

Applications Pyrrolidine-2,2,5,5-d4 (CAS# 42403-25-8) is a useful isotopically labeled research compound.

Applications Iodoethane-1-d1 (CAS# 3652-81-1) is a useful isotopically labeled research compound.

Applications DL-Phenyl-d5-alanine (CAS# 284664-89-7) is a useful isotopically labeled research compound.