Haluros orgánicos

<p>Applications 2,7-Dibromo-9H-fluorene is a useful building block for organic synthesis.<br></p>

<p>Applications 4-Fluoro-3-nitrobenzotrifluoride is an intermeidate used in the synthesis of 2-nitro-4-trifluoromethylphenylhydrazine, derivatization reagent for 1,2-diol compounds and oxo-steroids and [3-(2-nitro-4-trifluoromethylphenyl)aminophenyl]dihydroxyborane, derivatization reagent for 1,2-diol compounds and oxo-steroids.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Higashi, T., et al.: Anal. Sci., 18, 1301 (2002); Caci, E., et al.: Am. J. Physiol. Lung Cellular and Molecular Physiology, 285, L180 (2003)<br></p>

<p>Applications 2,4'-Dichlorobenzophenone is used in the synthesis of triarylcarbinol analogs of fenarimol as potent inhibitors of Trypanosoma cruzi. It can also be used to prepare fatty acid amide hydrolase inhibitors.<br>References Keenan, M., et al.: J. Med. Chem., 55, 4189 (2012); Roughley, S., et al.: Bioorg. Med. Chem. Lett., 22, 901 (2012)<br></p>

<p>Applications 2,4-Dibromobenzoic acid<br></p>

<p>Stability Volatile<br>Applications 1,2-Dichlorotrifluoroethyl trifluoromethyl ether (cas# 2356-53-8) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Bromoacetic Acid is a relatively strong alkylating agent as well as a versatile building block used very commonly in organic synthesis. Bromoacetic acid has been shown to reversibly inhibit human erythrocyte carbonic anhydrase B.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Song, C. et al.: J. Org. Synth., 74, 8980 (2009); Kramer, S.P. et al.: J. Nat. Cancer Inst., 31, 297 (1963); Whitney, P.L. et al.: Eur. J. Biochem., 16, 126 (1970);<br></p>

<p>Applications 5,6-dibromonicotinic acid (cas# 29241-64-3) is a useful research chemical.<br></p>

<p>Applications Used as a general reagent in acylation reactions. A byproduct formed in treated waters, and found in marine life.<br> E0<br>References Zuckermann, R.N. et al.; J. Am. Chem. Soc., 115, 10646 (1992); Bull, R., et al.: Toxicol. Appl. Pharmacol., 182, 55 (2002), Mitch, W., et al.: Water Sci. Technol., 2, 191 (2002),<br></p>

<p>Applications 1-Bromo-1,1-dichloro-2-propanone is a disinfection byproduct in drinking water.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Krasner, S., et al.: Environ. Sci. Technol., 40, 7175 (2006); Richardson, S., et al.: Water Air Soil Poll., 123, 95 (2000)<br></p>

<p>Applications 3-Chloropropiophenone is an impurity of Fluoxetine (F597100).<br>References Wirth, D.D. et al.: Chromatographia, 46, 511 (1997); Lacroix, P.M. et al.: J. AOAC Int., 78, 334 (1995);<br></p>

<p>Applications 3,5-Difluorobenzylamine is a useful reagent for reductive amination.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cantrill, S., et al.: J. Org. Chem., 66, 6857 (2001);<br></p>

<p>Stability Moisture Sensitive<br>Applications Trimethyltin Chloride is used as an endocrine disrupting compound, inducing adipogenesis through RXR and PPARγ activation.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Grun, F. et al.: Mol. Endocrinol., 20, 2141 (2006); Yano, K. et al.: J. Health Sci., 49, 195 (2003);<br></p>

<p>Applications Used as a reactant in the preparation of pyrimidinone ribosides and analogs that show anti-tumor properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Driscoll, J.S. et al.: J. Med. Chem., 34, 3280 (1991); Pan, L. et al.: J. Pharm. Biomed. Anal., 52, 589 (2010);<br></p>

<p>Applications 2,4-Dichloro-3,5-dinitrobenzotrifluoride is a reagent used in the synthesis of kinesin spindle protein inhibitors. Potential use as an alternative to neurotoxic MT inhibitors.<br>References Dong, J. et al.: Eur. J. Med. Chem., 70, 427 (2013);<br></p>

<p>Stability Moisture Sensitive<br>Applications A phosphorylating agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sartori: Chem. Rev., 48, (1951), Nachmansohn, et al.: Adv. Enzymology, 12, 259 (1951)<br></p>

<p>Applications Dimethyldimyristylammonium Chloride is used as a surfactant.<br>References Cipiciani, A., et al.: Austr. J. Chem., 44, 1505 (1991); Hueck, H., et al.: Appl. Microbiol., 14, 308 (1966)<br></p>

<p>Applications 1-Bromo-3-chloropropane can be used safer and equally efficient alternative to chloroform as a phase-separation agent in the 1-step method of RNA isolation from biological samples such as animal and plant tissue.<br>References Chomczynski, P. et al.: Anal. Biochem., 225, 163 (1995); Chey, S. et al.: Anal. Biochem., 411, 164 (2011);<br></p>

<p>Stability Moisture Sensitive<br>Applications 4-Chloro-3-nitrobenzoyl Chloride (cas# 38818-50-7) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Methyl 4-Chloropicolinate (cas# 24484-93-3) is a compound useful in organic synthesis.<br></p>

<p>Applications 1-Chlorododecane is used as a reagent in the chemical modification of zein to reduce the brittleness of zein films.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Shi, K., et al.: J. Agr. Food Chem., 59, 56 (2011)<br></p>

<p>Applications N-Iodoacetyltyramine is used in iodine-125 labelling of various molecules for chemical analysis.<br>References Lin, C. et al.: Anal. Biochem., 179, 389 (1989);<br></p>

<p>Applications 1-Bromo-2-chlorobenzene is a reagent in the preparation of arylpiperidines and aryltetrahydropyridines as 5-HT2C agonists.<br>References Conway, R.J., et al.: Bioorg. Med. Chem. Lett., 22, 2560 (2012)<br></p>

<p>Applications 3,5-Dinitrochlorobenzene is used to study strength and directionality of halogen bond are co-detected by the magnitude and size of the σ-hole.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kolar, M., et al.: Phys. Chem. Chem. Phys., 16, 9987 (2014);<br></p>

<p>Stability Moisture Sensitive<br>Applications Dimethyl chlorothiophosphate is an organophosphorus reagent that is used to synthesize phosphorus analogues of γ-aminobutyric acid, compounds that exhibit anticonvulsant properties. Dimethyl chlorothiophosphate is also used as a reagent to synthesize Parathion (P192220), a widely used pesticide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cates, L., et al.: J. Med. Chem., 27, 654 (1984); DeBruin, K. &amp; Boros, E.: J. Org. Chem., 55, 609 (1990); Hall, S.: J. Am. Chem. Soci., 72, 2768 (1950); Kotronarou, A. &amp; Hoffmann, M.: Env. Sci. Tech., 26, 1460 (1992)<br></p>

<p>Applications Intermediate in the preparation of imidazole antifungal agents.<br>References Albet, C. et al.; J. Pharmaceut. Biomed. 10, 205 (1992); Raga, M. et al.; Eur. J. Med. Chem. 21, 329 (1986)<br></p>

<p>Applications 4,6-Dichloronicotinic acid<br></p>

<p>Applications tert-butyl N-[3-(chlorosulfonyl)propyl]carbamate (cas# 1196153-59-9) is a useful research chemical.<br></p>

<p>Applications 2-Chloronicotinic Acid is used in the preparation of 4-thiazolidinone derivatives and Schiff bases displaying antimicrobial activity.<br>References Patel, N. et al.: Saudi Pharm. J., 18, 129 (2010); Patel, N. et al.: J. Sci. Islam Repub. Iran., 21, 121 (2010);<br></p>

<p>Applications 2-hydroxy-5-iodobenzoic Acid is a reagent in various organic chemical reactions leading to pharmaceutical compounds. It is involved in the synthesis of labelled benzamide analogs for tumor imaging as well as the synthesis of the dye, Congo Red, for biological analyses.<br>References Tu, Z. et al.: J. Med. Chem., 50, 3194 (2007); Sellarajah, S. et al.: J. Med. Chem., 47, 5515 (2004);<br></p>

<p>Applications 2-Chloro-N-phenylacetamide is used as a reagent in the synthesis of indolylmethylene benzo[h]thiazolo[2,3-b]quinazolinones which exhibit anticancer and antimicrobial activities in vitro.<br>References Gali, R., et al.: Bioorg. Med. Chem. Lett., 24, 4239 (2014)<br></p>

<p>Stability Hygroscopic<br>Applications Dihydrogen Hexachloroplatinate Hexahydrate is a reactant used in the synthesis of platinum, carbon dot hybrid nanoparticles.<br>References Shin, H. et al.: ACS. Catal., 6, 3914 (2016);<br></p>

<p>Applications p-Toluidine Trifluoroacetamide (cas# 350-96-9) is a compound useful in organic synthesis.<br></p>

<p>Applications 2,4-Diphenylpyrylium Tetrafluoroborate is derived from 4-Methoxy-3-buten-2-one (M261350), which is a reactant in the synthesis of hydroisoquinoline derivatives as an intermediate for the synthesis of manzamine.<br>References Mihara, Y., et. al.: Bull. Chem. Soc., 82, 1520 (2009)<br></p>

<p>Applications (3S)-4-Chloro-3-hydroxybutyronitrile is used in various organic precursor syntheses. It is used in the synthesis of hydroxypyrrolidinones to by used as carbapenem precursors. Also used in the preparation of atorvastatin (A791750) precursors. Impurity in the synthesis of Rosuvastatin (R700500), a selective, competitive HMG-CoA reductase inhibitor. Antilipemic.<br>References Kanno, O. et al.: Hetero., 53, 173 (2000); Watanabe, M., et al.: Bioorg. Med. Chem., 5, 437 (1997), Lee, E., et al.: Clin. Pharmacol. Ther., 78, 330 (2005), Ferdinand, K.C., et al.: Am. J. Cardiol., 97, 229 (2006); Jiang, C. et al.: Lett. Org. Chem., 9, 520 (2012);<br></p>

<p>Applications 1,3-Dichlorobenzene was used to study the effect of solvent vapor pressure on the vertical nanowire of C60 molecules. It can be detected in environmental samples using an advanced Fourier transform infrared spectroscopy-attenuated total reflectance (FTIR-ATR) sensor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kim, J.: ACS Nano, 7, 9122 (2013); Lu, R., et al.: Scientific Reports, 3, 2525 (2013)<br></p>

<p>Applications N-(2-(2,4,6-TRICHLOROPHENOXY)ETHYL)PROPAN-1-AMINE (cas# 67747-01-7) is a useful research chemical.<br></p>

<p>Stability Light Sensitive<br>Applications 1,2-Dichloroethylene (Mixture of cis and trans) is a chlorinated solvent used in organic synthesis. Environmental pollutant found in river ecosystems contributing to habitat degradation.Environmental toxin on US EPA Toxic Release Inventory list (TRI) list.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Schaefer, R. et al.: Freshwater Biol., 61, 2116 (2016);<br></p>

<p>Applications 1,3,5-TRIMETHYL-1,3,5-TRIS(3,3,3-TRIFLUOROPROPYL)CYCLOTRISILOXANE (cas# 2374-14-3) is a useful research chemical.<br></p>

<p>Stability Hygroscopic<br>Applications Quaternary ammonium salts useful as paint strippers, foaming stabilizers, and bactericidal lotions.<br>References Bhattacharya, S., et al.: Biochemistry, 37, 7764 (1998), Raspaud, E., et al.: Biophys. J., 74, 381 (1998), Asgatay, S., et al.: Int. J. Pharm., 285, 121 (2004), Goracci, L., et al.: ChemBioChem., 6, 197 (2005),<br></p>

<p>Applications Used to protect alcohols during organic synthesis.<br>References Shen, H., et al.: J. Med. Chem., 53, 2666 (2010), Qiang, L., et al.: Bioorg. Med. Chem. Lett., 20, 836 (2010),<br></p>

<p>Applications Difluoroacetic acid<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 4-chlorobenzamide (cas# 619-56-7) is a useful research chemical.<br></p>

<p>Applications 2-Bromo-3,3,3-trifluoropropene is a useful research chemical for organic synthesis and other chemical processes.<br>References Zhao, Q., et al.: Tetrahedron, 74, 6033 (2018); Zhang, M., et al.: Nat. Commun., 9, 1 (2018); Hou, X., et al.: Org. Process Res. Dev., 20, 989 (2016)<br></p>

<p>Stability Air Sensitive<br>Applications 2-(2,4-Diaminophenoxy)ethanol Dihydrochloride<br></p>

<p>Applications 1-Chlorodecane is a reagent in the preparation of antimycobacterial agents. Also used in the synthesis of antimalarial atovaquone derivatives.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Pathak, A. et al.: Bioorg. Med. Chem., 21, 1685 (2013); El Hage, S. et al.: Eur. J. Med. Chem., 44, 4778 (2009);<br></p>