Compuestos y reactivos bioquímicos

<p>Peptide H-DRVYI^HPFH-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>H-CGGVSAYLSRPSPFD-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-CGGVSAYLSRPSPFD-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-CGGVSAYLSRPSPFD-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-CGGVSAYLSRPSPFD-OH at the technical inquiry form on this page</p>

<p>Peptide derived from the gastrointestinal hormone Motilin, secreted from endocrine cells in the small intestines, mainly from the jejunum and duodenum, in response to the fasting, drinking water or the mechanical stimulus of eating.</p>

<p>Peptide substrate for the kallikrein-related peptidase 7 (KLK7), the most abundant KLK family protease in the stratum corneum (outermost layer of the epidermis). KLK family have been implicated in several key homeostatic processes and in skin diseases that feature impaired desquamation. Increased levels of KLK7, have been identified in the stratum corneum of patients with atopic dermatitis (AD). T-helper type 2 cytokines, including interleukin 4 (IL-4) and-IL-13, can stimulate expression of KLK7, suggesting a direct link between inflammation in AD and KLK7 levels.KLK7 cleaves its substrates after tyrosine or phenylalanine residues. This peptide contains a C-terminal 7-amino-4-methylcoumarin (AMC) fluorescent tag, which is quenched when linked to the peptide via the amide bond. AMC is cleaved from the peptide by KLK7, upon cleavage the AMC fluorescence is activated.</p>

<p>CD31 antibody was raised in mouse using lewis rat microglia as the immunogen.</p>

<p>ProBNP protein is a versatile product used in the field of Life Sciences. It is a protein that can be targeted with both polyclonal and monoclonal antibodies for various research purposes. The protein is commonly used in studies related to cardiomyocytes, as it plays a crucial role in cardiovascular health. ProBNP protein is also involved in the regulation of annexin, an inhibitory factor that affects cellular processes.</p>

<p>Residues 17-29 of the LL-37 peptide, also known as FK-13. FK-13 has near-similar anti-microbial and anti-cancer properties to LL-37. This core fragment also contains part of the LL-37 actin binding domain and can associate weakly with actin, actin binding protects this fragment from protease degradation.LL-37 is a member of the large cationic family of anti-microbial peptides called cathelicidins which have broad-spectrum anti-microbial activity and are expressed in many species. The only cathelicidin found in humans is LL-37- this is produced in epithelial cells, by proteolytic cleavage from the C-terminal of the hCAP-18 protein. LL-37 can be processed into several different forms of anti-microbial peptides. As well as its anti-microbial properties LL-37 also has anti-cancer properties and regulates many aspects of the innate immune system- overexpression of LL-37 has been linked to autoimmune diseases such as asthma and psoriasis.</p>

<p>Peptide H-SGRGKGGKGLGKGGAK-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>(S)-N-(2-(2-Cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)quinoline-4-carboxamide is a small molecule that inhibits protein interactions. It has a molecular weight of 312.5 and the chemical formula C10H14FN3O2. This drug can be used as a research tool in pharmacology, cell biology, and biochemistry to study protein interactions, ion channels, and receptor activation.</p>

<p>Peptide Ac-KLTWQELYQLK^YKGI-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>The hCG alpha antibody is a highly reactive monoclonal antibody that is used in various applications in the field of Life Sciences. It can be used for ultrasensitive detection of human chorionic gonadotropin (hCG) in human serum, making it a valuable tool for pregnancy testing and fertility studies. The hCG alpha antibody is also commonly used in flow immunoassays and other diagnostic assays to detect the presence of hCG.</p>

<p>Hemoglobin antibody was raised in mouse using purified human hemoglobin as the immunogen.</p>

<p>The Digoxigenin antibody is a powerful tool used in Life Sciences research. It is a monoclonal antibody that specifically binds to digoxigenin, a small molecule commonly used as a labeling reagent in molecular biology experiments. This antibody has been extensively validated for its high specificity and sensitivity in various applications.</p>

<p>CA 15-3 Grade II (Low Cross-reactivity), Part Purified is a life science tool for use in pharmaceutical and diagnostic applications. Please enquire for more information about CA 15-3 Grade II (Low Cross-reactivity), Part Purified including the price, delivery time and more detailed product information at the technical inquiry form on this page.</p>

<p>Keratin-Derived anti-microbial Peptides (KDAMPs), are peptide fragment of the intermediate filament protein cytokeratin 6A. They were originally isolated from lysates of human corneal epithelial cells. KDAMPs exhibit coil structures with low α-helical content and are smaller and more stable than other known host-expressed anti-microbials.Multiple length KDAMPs have been studied for their anti-microbial properties, and different fragments show different anti-microbial spectrums. The 19 mer KDAMP peptide is rapidly bactericidal against multiple clinical isolates of Pseudomonas aeruginosa, and shows even greater activity against-Streptococcus pyogenes. However it is not active against Staphylococcus aureus-or-Escherichia coli.</p>

<p>Leuprolide is a synthetic hormone that is used for the treatment of prostate cancer. It works by blocking the production of hormones called luteinizing hormone and follicle-stimulating hormone in the body. Leuprolide is also used to treat endometriosis, uterine fibroids, and early puberty. This drug has been shown to have an inhibitory effect on prostate cancer cells in vitro and in vivo.</p>

<p>Peptide H-ELPEHTVK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-MLTELEK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>

<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>

<p>Peptide H-K^RPPGFSPF-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-SFHAAAYVPAGR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-GVLLP^QK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>H-RPVNCLR-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-RPVNCLR-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-RPVNCLR-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-RPVNCLR-OH at the technical inquiry form on this page</p>

<p>Peptide H-ENPVVHFFKNIVTPR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-AAVENLPTFLVELSR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Compound 1 is a potent compound that induces apoptosis in cancer cells. It has been shown to activate the caspase-3 enzyme, which is responsible for the execution of apoptosis. Compound 1 has also been shown to induce a number of different cellular changes and is effective in treating xenografts in mice. Compound 1 was found to be more potent than other compounds, such as 3-methylindole-2-carboxaldehyde and 4-(dimethylamino)benzaldehyde, with an increased ability to inhibit the enzymatic activity of zinc ions at physiological concentrations. This compound has two functional groups: an aldehyde group and a hydrazone group.</p>

<p>The dodecapeptide AR71 prevents melanoma inhibitory activity (MIA) dimerisation and hence inhibits (MIA). It therefore has the potential to be used as a therapeutic in melanoma.</p>

<p>Peptide H-V^LSGEDKSNIK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-VVGA^VGVGK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Cell-permeable calmodulin (CaM) agonist that binds to the EF-hand/Ca2+-binding site and can activate phosphodiesterase in the absence of Ca2+ and inhibit Ca2+ mediated cytotoxicity and apoptosis.</p>

<p>Myelin oligodendrocyte glycoprotein (MOG) is a member of the immunoglobulin (Ig) protein superfamily and is expressed exclusively in the central nervous system on the surface of myelin sheaths and oligodendrocyte processes. MOG is expressed at the onset of myelination, and therefore is a potential marker for oligodendrocyte maturation.MOG contains an extracellular domain, a transmembrane domain, a cytoplasmic loop, a membrane-associated region and a cytoplasmic tail.  MOG may function as a cell surface receptor or cell adhesion molecule.  Fifteen different alternatively spliced isoforms have been detected in humans. These are present either on the cell surface, the endoplasmic reticulum in the endocytic system, or in secreted form.The secreted form of MOG may trigger autoimmunity if released into the cerebrospinal fluid and periphery. MOG is thought to be a key target for autoantibodies and cell-mediated immune responses in inflammatory demyelinating diseases such as multiple sclerosis (MS) and is therefore widely studied in this field.The MOG (35-55) fragment is the most potent auto-antigenic region of MOG, and the most effective at inducing experimental autoimmune/allergic encephalomyelitis (EAE), an animal model that resembles MS. This peptide has a free carboxylic acid at the C-terminus, an amide version is also available in our catalogue.</p>

<p>Peptide H-GSPAINVAMHVFR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Wilms tumor protein is a protein that is encoded by the WT1 gene on chromosome 11p in humans. WT1 is a tumour suppressor gene associated with the development of Wilms' Tumour, from which it was named. Mutations in exon 7 and 9 of WT1 have been recurrently identified in acute myeloid leukemia and associated with poorer prognosis and chemotherapy resistance.The WT1 peptide is a transcription factor that contains four zinc finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system.WT1 has been ranked by the National Cancer Institute (NCI) as the Number 1 target for cancer immunotherapy.The arginine is isotopically labelled with carbon-13(6) and nitrogen-15(4).</p>

<p>Peptide H-SLSLSP-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-YGRKKRRQRRRC-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide LCBiot-MACPGFLWALVISTCLEFSMA-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-EIPAWVPFDPAAQITK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Neuropeptide S (NPS) is a neuropeptide found in mammalian brains, primarily in neurons in the lateral parabrachial nucleus, the peri-locus coeruleus and the principle sensory 5 nucleus of the trigeminus. NPS in involved in several neuroendocrine, behavioural and inflammatory responses, including: reducing anxiety in mice- suppressing appetite and inducing wakefulness and hyperactivity. NPS treatment can be used to improve fear extinction in mice and limit fear memory retrieval after fear reduction training, thus making it an interesting target for treatment of post-traumatic stress disorder. NPS exerts its actions by binding to a G-protein coupled receptor, NPSR.</p>

<p>H-TLYKMGFPEAARKGNSL-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-TLYKMGFPEAARKGNSL-OH is provided at greater that &gt;90% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-TLYKMGFPEAARKGNSL-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-TLYKMGFPEAARKGNSL-OH at the technical inquiry form on this page</p>

<p>Peptide H-YNDDDTFTVK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide Ac-CVKKDQLGKN-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Fenprostalene is a drug that belongs to the group of polymeric matrix tablets. It is used for the treatment of endometriosis and ovarian activity. Fenprostalene has been shown to inhibit the release of acetylcholine from nerves and can be used to treat Parkinson's disease. Fenprostalene also has an anti-inflammatory effect by inhibiting prostaglandin synthesis, which may be due to its inhibition of acetylcholinesterase activity.</p>

<p>Peptide H-SIPQVSPVR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-MDILSYMR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide Ac-TTAI-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>CBL-B (239-247) Light.</p>

<p>Peptide H-KLWVIPQ-OH PAB-003-416B is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>The BAD peptide is a synthetic fragment derived from the BAD protein (Bcl-2-associated death promoter), a pro-apoptotic member of the BH3-only family within the larger Bcl-2 family of proteins. The BAD peptide typically contains the BH3 domain of the BAD protein, which is crucial for its role in promoting apoptosis by interacting with anti-apoptotic proteins such as Bcl-2 and Bcl-xL. The BH3 domain of BAD, found in the BAD peptide, binds to anti-apoptotic proteins like Bcl-2 and Bcl-xL. Normally, these anti-apoptotic proteins protect the cell by preventing the activation of pro-apoptotic proteins like Bax and Bak, which are responsible for permeabilizing the mitochondrial outer membrane, a key step in apoptosis.When the BAD peptide binds to Bcl-2 or Bcl-xL, it inhibits their ability to prevent apoptosis. This disruption allows Bax and Bak to become activated, leading to mitochondrial outer membrane permeabilization (MOMP), release of cytochrome c, and activation of downstream caspases that execute cell death.</p>

<p>Peptide H-FLPSDFFP^SV^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>