Compuestos y reactivos bioquímicos

<p>Peptide H-LLLEYLEEK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Highly purified Human CA 72-4 protein</p>

<p>Pregnant Mare Serum Gonadotropin (PMSG) is a peptide hormone that belongs to the group of glycoprotein hormones. It is found in the serum of pregnant mares and has pluripotent cell-differentiating properties, which may be due to its ability to regulate mitochondrial functions. PMSG also has biological effects on protein and nucleic acid synthesis, as well as on reproduction and development. PMSG is used in vitro methods for studying biological processes such as cell differentiation and proliferation, ocular disorders, and eye muscle function. The biological properties of PMSG have been studied in vivo using sephadex G-100 gel electrophoresis.</p>

<p>Peptide H-ALLFIPR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Beta tubulin antibody was raised in rabbit using a synthetic peptide derived from aa 416-430 of human tubulin beta as the immunogen.</p>

<p>Ac-Leu-Gly-Pro-Lys-Acc-NH2 is a peptide that has the amino acid sequence of Leu, Gly, Pro and Lys. It is an enzyme substrate that has a high specificity for thrombin. Ac-Leu-Gly-Pro-Lys-Acc-NH2 has been shown to have a kinetic constant of 0.063/min/mg and a kinetic rate of 0.21/min when incubated with thrombin at 37°C in phosphate buffer (pH 7.4).</p>

<p>H-Dab-Pip is a peptidase inhibitor that inhibits the enzyme known as dipeptidyl peptidase. It also inhibits the enzyme known as dipeptidyl peptidase, which is involved in the breakdown of dipeptides. H-Dab-Pip is an inhibitor of this enzyme and can be used to regulate blood pressure by inhibiting the breakdown of angiotensin II, a potent vasoconstrictor. H-Dab-Pip may also be used for diabetes treatments or for the treatment of inflammatory bowel disease.</p>

<p>Hydrochlorothiazide is a thiazide diuretic. It is used to treat high blood pressure and fluid retention. Hydrochlorothiazide lowers levels of electrolytes such as potassium, sodium, and chloride in the body by increasing the amount of water that is excreted. This drug has been shown to be effective in reducing disease activity and improving quality of life for patients with chronic inflammatory conditions such as rheumatoid arthritis and psoriasis.</p>

<p>L-type calcium channel blocker</p>

<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>

<p>Alpha 2 macroglobulin antibody was raised in goat using human alpha-2-macroglobulin as the immunogen.</p>

<p>Peptide H-LDAQASFLPK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Thyroglobulin antibody was raised in mouse using human thyroblogulin as the immunogen.</p>

<p>Ac-QSRVTHPHLPRALMRSC-NH2 is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. Ac-QSRVTHPHLPRALMRSC-NH2 is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer Ac-QSRVTHPHLPRALMRSC-NH2 in bulk quantities in addition to our standard pack sizes.Please enquire for more information about Ac-QSRVTHPHLPRALMRSC-NH2 at the technical inquiry form on this page</p>

<p>H-VPCILPIIENGK-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-VPCILPIIENGK-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-VPCILPIIENGK-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-VPCILPIIENGK-OH at the technical inquiry form on this page</p>

<p>Orelabrutinib is a small-molecule Bruton’s tyrosine kinase (BTK) inhibitor, which is synthesized chemically. This selective inhibitor targets BTK, a key enzyme involved in the B-cell receptor signaling pathway. By binding covalently to cysteine-481 in BTK, orelabrutinib effectively blocks the downstream signaling, leading to apoptosis of malignant B-cells.</p>

<p>Purified recombinant stabilized Human Streptolysin O protein</p>

<p>IgM, Highly Purified is a life science tool for use in pharmaceutical and diagnostic applications. Please enquire for more information about IgM, Highly Purified including the price, delivery time and more detailed product information at the technical inquiry form on this page.</p>

<p>The CRP antibody is a highly effective monoclonal antibody that targets collagen and colony-stimulating factors. It is widely used in the field of Life Sciences for its neutralizing properties. This antibody specifically binds to molecules such as m-CSF, TGF-beta, actin, alpha-fetoprotein, and colony-stimulating factors. It has been shown to have toxic effects on targeted cells, making it a valuable tool in various research applications. Additionally, the CRP antibody has been incorporated into nanocomposites for enhanced delivery and efficacy. Its ability to inhibit TNF-alpha synthesis further adds to its potential therapeutic applications.</p>

<p>A cannabinoid receptor agonist, which binds more selectively to CB2 than CB1 receptors (1000-fold). GW833972A inhibits vagus nerve depolarization induced by tussive agents, such as hypertonic saline (EC50 = 6.5 μM), capsaicin (EC50 = 33.9 μM) or PGE2 (EC50 = 15.9 μM).</p>

<p>Immune suppressant; prevents pro-inflammatory cytokine release</p>

<p>Lypressin is a synthetic nonapeptide that functions as an analog of the natural hormone vasopressin, which is endogenously produced in the posterior pituitary gland. Its primary mode of action involves binding to vasopressin receptors in the renal collecting ducts, where it promotes water reabsorption, thereby exhibiting antidiuretic effects. Additionally, Lypressin has some vasopressor activity, though it is less potent in this regard compared to natural vasopressin.</p>

<p>LL-37 is a member of the large cationic family of anti-microbial peptides called cathelicidins which have broad-spectrum anti-microbial activity and are expressed in many species. The only cathelicidin found in humans is LL-37, this is produced in epithelial cells, by proteolytic cleavage from the C-terminal of the hCAP-18 protein. LL-37 can be processed into different forms of anti-microbial peptides. As well as its anti-microbial properties LL-37 also regulates many aspects of the innate immune system and overexpression of LL-37 has been linked to autoimmune diseases such as asthma and psoriasis, making LL-37 the most studied form of the human cathelicidin peptides.More recently, studies have shown that LL-37 binds to SARS-CoV-2 S protein and inhibits binding to its receptor hACE2, which may inhibit viral entry into the cell. LL-37 is upregulated by vitamin D, therefore this may be one mode of action for the positive outcomes seen with vitamin D treatment for Covid-19.</p>

<p>The Zika virus envelope protein is a glycoprotein that plays a crucial role in the transfer reactions of the virus. It is responsible for binding to host cells and facilitating viral entry. This protein has been extensively studied and is now used in various immunoassays, including neutralizing assays and enzyme-linked immunosorbent assays (ELISAs). Monoclonal antibodies targeting the Zika virus envelope protein have been developed and are widely used in research and diagnostic applications. Additionally, this protein has shown potential as a target for therapeutic interventions, such as the development of antiviral drugs or vaccines. Its unique characteristics make it an important component in the field of Life Sciences, specifically in the study of Proteins and Antigens.</p>

<p>Please enquire for more information about C.I.Solvent Blue 24 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>VE 822 is a potent and selective inhibitor of ATR protein kinase, which is derived through chemical synthesis with a high specificity for ATR over related kinases. ATR, or ataxia telangiectasia and Rad3-related kinase, plays a critical role in the cellular response to DNA damage and replication stress. VE 822 achieves its mode of action by interfering with ATR’s catalytic activity, thereby halting the DNA damage response and rendering cancer cells more susceptible to DNA-damaging agents.</p>

<p>Peptide H-MDRTSASQQSNYGKC-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>PC Biotin Alkyne probes eliminate a major limitation of the streptavidin-biotin affinity purification. This reagent contains a biotin moiety linked to an azide moiety through a spacer arm containing a photocleavable linker. Captured biomolecules can be efficiently released under mild, reagent-free conditions (irradiation with near-UV, low intensity lamp) and the small molecular fragment (55.07 Da) left on the labelled protein following cleavage. These features make the photocleavable probe especially attractive for use in biomolecular labelling and proteomic studies.</p>

<p>Please enquire for more information about VZV IgG Positive Human Plasma including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>H-IQFKPDDGTTPDR-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-IQFKPDDGTTPDR-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-IQFKPDDGTTPDR-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-IQFKPDDGTTPDR-OH at the technical inquiry form on this page</p>

<p>HBsAg antibody (Subtype ad/ay) was raised in goat using human hepatitis B surface antigen as the immunogen.<br>The term HBsAg collectively refers to the three particle forms: Dane, filamentous, and spherical of the Hepatitis B (HB) virus which are made up of small HBs proteins (SHBs), middle HBs proteins (MHBs), and large HBs proteins (LHBs). These HBsAg proteins envelop the viral nucleocapsid and bind to the viral core. The LHB has a pre-S1, pre-S2, and S domain, the MHB does not have this pre-S1 domain while SHBs only have the S domain. The S domain's ability to form disulfide cross-linked dimers allows Dane particles of the HBsAg to interact with sulfated proteoglycans on host cells, resulting in HB infection. Furthermore, residues 2-48 which make up a conserved N-terminal sequence on the pre-S1 domain, allow HBsAg to bind to the Na+-Taurocholate Co-transporter Polypeptide (NTCP) on hepatocytes.<br>This antibody has potential for use in research and diagnostic applications of HB infection, a necro-inflammatory liver disease that can cause liver cirrhosis and hepatocellular carcinoma.</p>

<p>Smoothened (SMO) receptor antagonist</p>

<p>Inhibitor of CDK7 kinase</p>

<p>Urate oxidase is a flavoenzyme that catalyses the oxidation of uric acid to allantoin. It is present in many organisms, including fungi and primates. Urate oxidase catalyzes the oxidation of uric acid to allantoin via the reduction of oxygen to water with concomitant production of hydrogen peroxide. There are four forms of urate oxidase found in nature: tetrameric, dimeric, monomeric, and recombinant. The recombinant form has been shown to be effective against hyperuricaemia in primates and humans with lymphoid malignancies.</p>

<p>Peptide Ac-HHHHHH-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Dyrk1a antibody was raised in rabbit using the N terminal of Dyrk1a as the immunogen</p>

<p>Potentially suitable for ELISA, lateral Flow, ChLIA and other applications. This antibody will self-pair and can be used as both capture and label elements in immunoassay.</p>

<p>ApoB antibody was raised in mouse using human serum LDL as the immunogen.</p>

<p>Peptide H-QESEVEEPL^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>H-YEEISDPPEDDE-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-YEEISDPPEDDE-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-YEEISDPPEDDE-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-YEEISDPPEDDE-OH at the technical inquiry form on this page</p>

<p>H-ALVASLPGQLQYK-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-ALVASLPGQLQYK-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-ALVASLPGQLQYK-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-ALVASLPGQLQYK-OH at the technical inquiry form on this page</p>

<p>Lyme Disease (Borrelia) IgM Positive Human Serum for diagnostics</p>

<p>Furosemide is a potent loop diuretic that is used in the treatment of hypertension, liver cirrhosis, renal disease and heart failure. This drug acts on the kidney to increase water loss from the body. It inhibits electrolyte reabsorption. Furosemide also exerts vasodilatory effects.</p>

<p>Agonist of cannabinoid receptors CB1 and CB2</p>

<p>Sulfo-SPDB-DM4 is a conjugate of a monoclonal antibody and the active form of eribulin. It is used as an anticancer drug to treat patients with cancer, such as breast cancer and prostate cancer. The pharmacokinetic properties of this drug have been studied in CD-1 mice bearing tumor xenografts. Sulfo-SPDB-DM4 binds to the antigen expressed by the tumor cells, which leads to an increase in the number of receptors on the surface of tumor cells. This leads to increased uptake and accumulation of eribulin in tumor cells, resulting in inhibition of cell proliferation.</p>

<p>SARS-CoV-2 Nucleocapsid Antigen (SA Variant – B.1.351), Recombinant is a life science tool for use in pharmaceutical and diagnostic applications. Please enquire for more information about SARS-CoV-2 Nucleocapsid Antigen (SA Variant – B.1.351), Recombinant including the price, delivery time and more detailed product information at the technical inquiry form on this page.</p>

<p>Glucocorticoid receptor agonist; anti-inflammatory; immunosuppressant</p>

<p>H-TSWRCTRVG-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-TSWRCTRVG-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-TSWRCTRVG-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-TSWRCTRVG-OH at the technical inquiry form on this page</p>

<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>

<p>Natalizumab LC46-58 KSN deimmunised</p>