Anticuerpos para la investigación del cáncer

<p>Letrozole (CGS 20267) is an Aromatase Inhibitor. The mechanism of action of letrozole is as an Aromatase Inhibitor.</p>

<p>Isosulfan blue, a blue dye used in lymphangiography and sentinel node biopsies, may cause allergies.</p>

<p>CWP232228 is a selective Wnt/β-catenin pathway inhibitor targeting β-catenin/TCF binding, halting breast/liver CSC growth and metastasis safely.</p>

<p>Deferoxamine Mesylate (DFOM) is an iron chelator and iron death inhibitor.</p>

<p>This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with Human INHbA protein. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human INHbA. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human INHbA in the samples is then determined by comparing the OD of the samples to the standard curve.</p>

<p>Vecuronium bromide (ORG NC 45) is a synthetic, intermediate-acting mono-quaternary steroid and non-depolarizing neuromuscular blocking agent, with muscle</p>

<p>RUVBL1/2 ATPase-IN-1 inhibits RUVBL1/2 ATPase (IC50: 6.0/7.7 μM); useful in cancer research.</p>

<p>Ibuprofen, an NSAID, reduces pain, inflammation, and fever by limiting prostaglandin production.</p>

<p>Sulfisoxazole: a short-acting antibacterial targeting gram-positive/negative bacteria and inhibits breast cancer exosome by affecting endothelin receptor A.</p>

Metoprolol Tartrate is a blocker of the cardioselective β-adrenergic receptor.

<p>PTC299 ((4-chlorophenyl) (1S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carboxylate) is an orally active inhibitor of VEGFA mRNA</p>

<p>LCH-7749944 suppresses human gastric cancer cell growth, induces apoptosis, and inhibits PAK4 with IC50 of 14.93 μM.</p>

<p>This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with Mouse INHbB protein. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse INHbB. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse INHbB in the samples is then determined by comparing the OD of the samples to the standard curve.</p>

<p>Mitoxantrone dihydrochloride (NSC-301739) is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone is a type II topoisomerase inhibitor.</p>

<p>Oxiconazole nitrate (Ro 13-8996) is an antifungal imidazole inhibiting fungal growth by blocking ergosterol synthesis, disrupting cell membranes.</p>

<p>Niacin is a water-soluble B vitamin with antihyperlipidemic effects, found in food and converted to niacinamide for coenzyme activity.</p>

<p>This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with Mouse TRF protein. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse TRF. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse TRF in the samples is then determined by comparing the OD of the samples to the standard curve.</p>

<p>PXR antagonist 70: selective PXR blocker, IC50 = 540 nM, Ki = 390 nM, boosts cancer cell chemosensitivity.</p>

<p>Orally active SERM, Estrogen receptor modulator 1 (pIC50: 0.46), reverses Tamoxifen-resistant tumors.</p>

SK33 is a potent and tissue selective anti-androgen agent. SK33 reduces androgen receptor (AR) transcriptional activity.

<p>Antiproliferative agent-13 is a compound with antiproliferative activity.</p>

<p>Nizatidine (Acinon) is a competitive and reversible histamine H2-receptor antagonist with antacid activity.</p>

<p>MS1943 is a orally bioavailable EZH2 selective degrader(IC50 of 120 nM).</p>

<p>MST-312, a telomerase inhibitor derived from green tea's EGCG, has research potential in cancer, including MM.</p>

<p>GLL 398 is an orally active and selective degrader of estrogen receptor with an IC50 of 1.14 nM. GLL 398 blocks tumor growth in xenograft breast cancer models.</p>

<p>FAK-IN-7 has potential antiproliferative activity and is a FAK inhibitor.</p>

<p>3',4'-Dimethoxyflavone is a standard compound of flavonoids with numerous medicinal activities.</p>

<p>BMS-599626 (AC480) has been used in trials studying the treatment of Cancer, Metastases, and HER2 or EGFR Expressing Advanced Solid Malignancies.</p>

<p>BAY1082439, an orally bioavailable, selective inhibitor of PI3Kα/β/δ, demonstrates high efficacy in inhibiting the growth of Pten-null prostate cancer [1][2].</p>

<p>MKC-1 (Ro-31-7453) is an oral bisindolylmaleimide inhibitor that disrupts tubulin polymerization, potentially halting cancer cell division.</p>

<p>IPI-9119 is an orally active, selective and irreversible FASN inhibitor (IC50 = 0.3 nM).</p>

<p>CS1: BODIPY-based sensor detects Cu+ selectively in bio samples; visible via all fluorescence microscopes.</p>

Erythromycin (E-Mycin) is a Macrolide and Macrolide Antimicrobial. The physiologic effect of erythromycin is by means of Decreased Sebaceous Gland Activity.

<p>xnum compounds associated with colorectal cancer that can be used for high-throughput and high-content screening.</p>

<p>A unique collection of xnum compounds with anti-ovarian cancer therapeutic activity, can be used for anti-ovarian cancer drug discovery and pharmacological</p>

<p>xnum glycometabolism-related comounds, can be used for HTS and HCT;</p>

<p>K-975 is a highly selective, orally active TEAD inhibitor, effectively inhibiting protein-protein interactions between TEAD and YAP1/TAZ.</p>

<p>SP-96: Aurora B inhibitor, IC50=0.316 nM, selectively hinders MDA-MD-468 growth, GI50=107 nM, for triple-negative breast cancer research.</p>

<p>A unique collection of 420 compounds targeting PI3K/Akt/mTOR signaling for research in PI3K/Akt/mTOR signaling, and drug discovery in diseases involved with</p>

<p>A unique collection of xnum glutamine metabolism related compounds can be used for high throughput screening (HTS) and high content screening (HCS), and also is</p>

<p>xnum methylation-related compounds that can be used for high-throughput and high-content screening.</p>

<p>xnum well-chosen unique AMPK-targeted small molecules；</p>

<p>A unique collection of 385 bioactive lipids related compounds for high throughput screening (HTS) and high content screening (HCS), including Agonists &amp;amp;</p>

<p>A unique collection of 8328 inhibitors for research in cell signaling, high throughput screening (HTS) and high content screening (HCS) for new drugs;</p>

<p>76 exosome-related compounds that can be used for high-throughput and high-content screening.</p>

<p>6,8-Diprenylnaringenin (Senegalensin) is a natural product from hop Humulus lupulus.</p>

<p>555 glycolysis-related active compounds for high-throughput and high-content screening.</p>

<p>A unique collection of xnum GPCR-active agents for high throughput screening and high content screening for GPCR drug discovery, and new GPCR target</p>

<p>A unique collection of xnum chemokines or chemokine receptors targeted compounds for high throughput and high content screening;</p>