Heterociclos con oxígeno (O)

Applications 2-(Furan-2-yl)-2-(methoxyimino)acetic Acid is an intermediate in the synthesis of Cephalosporin derivatives.
References Ger. Offen. (1978), DE 2731724 A1 19780119.

Applications Tetrahydro-2-furanmethanamine is used in the synthesis of novel topoisomerase I targeting anti-cancer agents with mild to potent cytotoxic activity. Also used in the discovery and synthesis of orally bioavailable stearoyl-CoA desaturase 1 inhibitors
References Lopez-Rodriguez, M. et al.: 44, 4504 (2001); Liu, G. et al.: J. Med. Chem., 50, 3086 (2007);

Applications 2,3,5-Trimethylfuran (cas# 10504-04-8) is a useful research chemical.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 6-Amino-5-(1,1-dimethylethyl)-3,3-dimethyl-2(3H)-benzofuranone is an intermediate in synthesizing Ivacaftor Carboxylic Acid (I940605). It is an impurity of Ivacaftor (I940600); a drug used in the treatment of cystic fibrosis.
References Clancy, J. et al.: Am. J. Resp. Crit. Care. Med., 186, 593 (2012)

Applications 2,5-DIMETHOXYTETRAHYDROFURAN (cas# 696-59-3) is a useful research chemical.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications (R)-5-Oxotetrahydrofuran-2-carboxylic Acid is an intermediate used to synthesize 2',3'-dideoxy-4'-selenonucleosides as potential antiviral agents.
References Jeong, L., et al.: Bioorg. Med. Chem., 16, 9891 (2008)

Applications Used in the preparation of D-xylofuranose derivatives.

Applications (R)-2-(Benzyloxy)-5-((5-oxotetrahydrofuran-2-yl)methyl)phenyl Neopentyl Sulfate is an intermediate in the synthesis of metabolite of (-)-Epicatechin (E582260).

Applications 5-(1,1-Dimethylethyl)-3,3-dimethyl-6-nitro-2(3H)-benzofuranone is an intermediate in synthesizing Ivacaftor Carboxylic Acid (I940605). It is an impurity of Ivacaftor (I940600); a drug used in the treatment of cystic fibrosis.
References Clancy, J. et al.: Am. J. Resp. Crit. Care. Med., 186, 593 (2012)

Applications 2-Cyano-N-((furan-2-ylmethyl)carbamoyl)acetamide is an intermediate in the synthesis of novel 1- and 8-substituted-3-furfuryl xanthines as adenosine receptor antagonists.
References Balo, M. C., et al.: Bioorg. Med. Chem., 17, 6755 (2009);

Applications Methyl 4-Bromofuran-2-carboxylate is used to prepare pyrimidinamines and pyridinamines as adenosine receptor modulators for treatment of CNS disorders.
References Borroni, E., et al.; PCT Int. Appl., WO 2001062233 A2 20010830 (2001)

Applications Intermediate in the production of Bufuralol Hydrochloride

5-Formylfuran-2-boronic acid is a compound that has been shown to be used in the synthesis of Pd complexes. This compound was found to inhibit the soluble guanylate cyclase and sirtuin 2 enzyme. It also has been shown to have anti-cancer effects, as it may inhibit cancer cell proliferation. 5-Formylfuran-2-boronic acid has been shown to increase the transport properties of potassium dichromate, which may be due to its acidic nature. This red fluorescent compound is soluble in organic solvents and can be activated by light. The optimum concentration of 5-Formylfuran-2-boronic acid is 3 mM in an acidic solution at room temperature.