Heterociclos con nitrógeno (N)

<p>Please enquire for more information about 2-((4-(2-Fluorophenyl)piperazinyl)carbonyl)cyclohexanecarboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 3-(N-(2-(3,4-dimethoxyphenyl)ethyl)carbamoyl)pyridine-2-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 4-[(1H-Benzimidazol-2-yl)oxy]-3-methyl-2-pyridinecarboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about N-(4-(methylpropyl)phenyl)-2-pyrimidin-2-ylthioethanamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-{[3-chloro-5-(trifluoromethyl)-2-pyridinyl]sulfanyl}acetohydrazide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-(4,6-dimethylpyrimidin-2-ylthio)-N-(4-iodophenyl)acetamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about ethyl 4-(N-propylcarbamoyl)piperazinecarboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 5-Nitro-2-(2'-pyridinethio)benzaldehyde including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-(4-(tert-Butyl)phenoxy)pyridine-3-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about ethyl 2-(4-(pyrimidin-2-ylamino)-3,5-thiazolyl)acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about N-(3,5-bis(trifluoromethyl)phenyl)-2-pyrimidin-2-ylthioethanamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 5-Methyl-3-(4-phenylpiperazinyl)cyclohex-2-en-1-one including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-(4-Nitrophenoxy)-3-chloro-5-trifluoromethyl pyridine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>1-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-4-piperidinecarboxylic acid (3CFP) is a phenoxy carboxamide that is an anticonvulsant. 3CFP has been shown to be effective in animal models of seizure and has a potency that exceeds that of phenobarbital. It also has potent anticonvulsant activity against seizures induced by pentylenetetrazole and electroshock. 3CFP binds to the GABA receptor, which is important for the regulation of neuronal excitability and is the target for many types of antiepileptic drugs. The chlorine atom in 3CFP may contribute to its pharmacological properties because it can form a covalent bond with amino acids like cysteine, which are important for protein synthesis.</p>

<p>Please enquire for more information about 4-Oxo-4-(4-(3-phenylprop-2-enyl)piperazinyl)but-2-enoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Applications (3S,​4S)​-​4-​Hydroxy-​3-​pyrrolidinyl Carbamic Acid 1,​1-​Dimethylethyl Ester was used as a chiral pyrrolidine to sense chirality with a liquid crystalline dynamic helical poly(phenylacetylene) bearing ethyl phsophonate pendant groups.<br>References Morimoto, M., et al.: J Polym Sci, 48, 1383 (2010).<br></p>

<p>Applications 6-(4-(hydroxymethyl)piperidin-1-yl)pyridazine-3-carboxylic acid (cas# 1178931-24-2) is a useful research chemical.<br></p>

<p>Applications 4-Amino-2-chloro-3-methylbenzonitrile is a reagent used in synthesis of imidazolin-2-ones, which is designed and synthesized as highly potent, orally active and muscle selective androgen receptor modulators (SARMs).<br>References Li, J. J., et al.: J. Med. Chem., 50, 3015-3025 (2007)<br></p>

<p>Applications N-Boc-2-pyrrolidinone is a useful synthetic intermediate. It can be used to prepare highly functionalized N-acyl-2-vinylpyrrolidines by a 4-component Ugi reaction (isocyanide, carbonyl compounds, primary amines, carboxylic acids). It can also be used to synthesize the naturally occurring Maillard flavors via catalytic SeO2 oxidation.<br>References Banfi, L., et al.: J. Org. Chem., 73, 1608 (2008); Fuganti, C., et al.: Tetrahedron, 63, 4762 (2007)<br></p>

<p>Applications 5-(Aminomethyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one Hydrochloride is a useful research chemical.<br></p>

<p>Applications 2-Chloro-4-iodo-5-(trifluoromethyl)pyridine is used in preparation of pyridine-2,4-diamine derivatives as FAK inhibitors for the treatment of arthritis, inflammatory and immune disorders.<br>References Lide, D., et al.: J. Chem. Phys., 29, 914 (1958), Giovannini, E., et al.: Helv. Chim. Acta, 42, 1142 (1959),<br></p>

<p>Applications 6'-Amino-1,6-dihydro-2-methyl-6-oxo[3,3'-bipyridine]-5-carbonitrile is a reagent used in the preparation of cardiotonic agents.<br>References Yamanaka, M. et al.: Chem. Pharm. Bull., 40, 666 (1992);<br></p>

<p>Applications 3-Amino-5-bromopyridine-2-carboxylic acid<br></p>

<p>Applications 4'-(Imidazol-1-yl)acetophenone (cas# 10041-06-2) is a useful research chemical.<br></p>

<p>Applications 6-Fluoro-4-methyl-2-pyridinamine can be synthesized from 2,6-Dichloro-4-methylpyridine (39621-00-6).<br></p>

<p>Applications Adenosine analog<br>References Barbieri, D., et al.: Bioorg. Med. Chem. Lett., 8, 2533 (1998),<br></p>

<p>Applications 2-Hydroxypyridine-N-oxide-d5 is the labelled analogue of 2-Hydroxypyridine-N-oxide (H953633), a reactant that is useful along wtih (S)-1-phenylethylamine and EDC·HCl for the synthesis of AZD8186, a potent and selective Inhibitor of PI3Kβ and PI3Kδ.<br>References B. Barlaam., et al.: J. Med. Chem., 58, 943-62 (2015);<br></p>

<p>Applications 3-(difluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyridine-6-carboxylic acid (cas# 1394042-15-9) is a useful research chemical.<br></p>

<p>Applications 6-chloro[1,2,4]triazolo[4,3-b]pyridazin-3(2H)-one (cas# 33050-32-7) is a useful research chemical.<br></p>

<p>Applications 5-AMINO-2-MERCAPTOBENZIMIDAZOLE (cas# 2818-66-8) is a useful research chemical.<br></p>

<p>Applications 3-Amino-4-cyanopyrazole (cas# 16617-46-2) is a compound useful in organic synthesis.<br>References La Motta, C., et al.: J. Med. Chem., 52, 1681 (2009), Rana, S., et al.: Bioorg. Med. Chem. Lett., 19, 670 (2009),<br></p>

<p>Applications OXAZOLE-5-CARBOXYLIC ACID HYDRAZIDE (cas# 885274-30-6) is a useful research chemical.<br></p>

<p>Applications 2-Oxopiperazine-3,3,5,5,6,6-d6 (CAS# 1219803-71-0) is a useful isotopically labeled research compound.<br></p>

<p>Applications N-(4-Methoxybenzyl)-N-2-pyridinyl-1,2-ethanediamine (cas# 109912-28-9) is a compound useful in organic synthesis.<br></p>

<p>Applications Compound has been shown to reversibly block voltage-dependent potassium channels, and is also a common impurity from the synthesis of compounds found in hair dyes<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Williams, D.M., et al.: J. Biol. Chem., 275, 38127 (2000), Munoz-Caro, C., et al.: Biophys. Chem., 96, 1 (2002),<br></p>

<p>Applications 2-Hydroxy-N-(pyridin-4-yl)butanamide is a useful synthetic intermediate.<br></p>

<p>Applications 2-Hydroxypyrimidine Hydrochloride, is used as a reagent in the synthesis of BI 207524, an indole diamide NS5B thumb pocket 1 inhibitor with improved potency for potential treatment of chronic hepatitis C virus infection.<br>References Beaulieu, P.L., et al.: J. Med. Chem., 57, 10130 (2014)<br></p>

<p>Applications (2-[(4-Chlorobenzoyl)-(5-trifluoromethylpyridin-2-yl)amino]-ethyl)-trimethyl-ammonium Iodide is a useful synthetic intermediate.<br></p>

<p>Applications 4,5-Dicyanoimidazole is commonly used in activation of nucleoside phosphoramidites during solid-phase oligonucleotide synthesis, and synthesis of nucleoside phosphoramidites, synthesis of novel nucleosides. IT is often used as an alternative to Tetrazole (T307500).<br>References Vargeese, C., et al.: Nucleic Acid Res.,  26 1046 (1998); Jin, Y., et al.: Tetrahedron Lett., 37, 973 (1996); Lackey, J., et al.: J. Am. Chem. Soc., 131, 8496 (2009)<br></p>

<p>Applications 4-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzonitrile (cas# 31489-18-6) is a useful research chemical.<br></p>

<p>Applications 1-(4-Hydroxyphenyl)piperazine<br></p>

<p>Applications 3-(piperidin-4-yl)-6-(pyrrolidin-1-yl)pyridazine (cas# 1955520-87-2) is a useful research chemical.<br></p>

<p>Applications 6-(Dimethylamino)pyridine-3-boronic acid<br></p>

<p>Applications 1-Ethyl-3-piperidinone Hydrochloride used in preparation of Aminoimidazoles.<br>References Sabbasani, Venkata R., et al.: Angewandte Chemie, 58, 18913-18917 (2019);<br></p>

<p>Applications N-[5-(4-Bromophenyl)-6-[2-(2-pyrimidinyloxy)ethoxy]-4-pyrimidinyl]-N'-propyl-sulfamide is a degradation product of Macitentan (M105005).<br>References Thummar, Mohit, et al.: Chromatographia, 81(3), 525-531 (2018)<br></p>

<p>Applications 4-Pyridineacetic Acid Hydrochloride is used in the preparation of a highly tumor-selective organometallic ruthenium(II)-Arene complex.<br>References Clavel, C.M., et. al.: J. Med. Chem., 57, 3546 (2014)<br></p>

<p>Applications 3-amino-6-cyanopyridazine (cas# 340759-46-8) is a useful research chemical.<br></p>

<p>Applications Methyl 5-Oxopyrrolidine-3-carboxylate has been used as a reactant in the synthesis of tert-butyloxycarbonyl protected 4,5-methano-β-proline.<br>References Tymtsunik, A.V., et. al.: Tetrahedron Lett., 55, 3312 (2014)<br></p>

<p>Applications Bimodal effect of the picolinic acid derivatives on the rate of wheat and pea germination.<br>References Hamaker, J., et al.: Science, 141, 363 (1963),<br></p>

<p>Applications The preparation and incorporation of 2-[2-[2-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]acetic Acid into the bilayers of liposomal constructs used for immunization with synthetic peptides.<br>References Frisch, B., et al.: Bioconjugate Chem., 7, 180-186 (1996)<br></p>

<p>Applications 6-Methyl-3-pyridineacetonitrile is a reactant used in the preparation of pyrazolopyrimidine derivatives as agents for treatment of autoimmune diseases and orally active corticotropin-releasing factor receptor antagonists.<br>References Chen, C. et al.: J. Med. Chem., 47, 4787 (2004)<br></p>

<p>Applications Octahydro-1H-pyrrolo[3,4-b]pyridine-d2 Di-trifluoroacetate is an intermediate in the synthesis ofhybrid antibacterial agents that exhibits inhibitory activities towards DNA Polymerase-Topoisomerase.<br>References Zhi, C.X., et al.: J. Med. Chem., 49, 1455 (2006);<br></p>

<p>Applications 1-(2-Chlorophenyl)-3-phenyl-4-(m-tolyl)-6,8-dihydro-1H-pyrazolo[3,4-e][1,4]thiazepin-7(4H)-one is an intermediate for the synthesis of 1-(2-Chlorophenyl)-1,4,6,7-tetrahydro-4-(3-methylphenyl)-7-oxo-3-phenyl-8H-pyrazolo[3,4-e][1,4]thiazepine-8-acetic Acid (C597045).<br></p>

<p>Applications 2,5-Diamino-4,6-dichloropyrimidine is a useful reagent for the preparation of Abacavir impurities, carbocyclic and hexenopyranosy nucleosides.<br>References Satyanarayana, G. V., et al.: Pharma Chemica, 7, 90 (2015)<br></p>

<p>Applications 1-Acetyl-1H-pyrazole-4-boronic acid, pinacol ester<br></p>

<p>Applications 4,6-Dichloropyrazolo[3,4-d]pyrimidine (cas# 42754-96-1) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 6-Methoxy-4-pyrimidinamine is used in the synthesis of carbamothiolacrylamides as selective EP2 antagonists in the treatment of neurodegenerative peripheral diseases. Also used in the preparation of PARP-1 inhibitors.<br>References Ganesh, T. et al.: ACS Med. Chem. Lett., 4, 616 (2013); Rhee, H. et al.: Bioorg, Med. Chem., 17, 7537 (2009);<br></p>