Heterociclos con nitrógeno (N)

<p>Applications 6-Bromo-2-fluoropyridin-3-ol (cas# 850142-72-2) is a useful research chemical.<br></p>

<p>Applications 5-Bromopyrimidine (cas# 4595-59-9) is a compound useful in organic synthesis.<br></p>

<p>Applications 5-fluoro-4-hydrazino-2-methoxypyrimidine (cas# 166524-64-7) is a useful research chemical.<br></p>

<p>Applications 4,6-Dichloro-5-fluoropyrimidine<br></p>

<p>Applications A chiral fluoro-pyridine derivative used in the preparation of dihydropyrrolopyrimidinone derivatives for use as MARK inhibitors.<br></p>

<p>Applications 1-ACETYL-2-PIPERIDINEACETIC ACID (cas# 25393-20-8) is a useful research chemical.<br></p>

<p>Applications 4-(ethylamino)-6-(isopropylamino)-1,3,5-triazine-2-thiol (cas# 5498-17-9) is a useful research chemical.<br></p>

<p>Applications 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido-[2,3-d]pyrimidin-7(8H)-one is used to prepare pyridino[2,3-d]pyrimidin-7(8H)-one derivatives as CDK4 and/or CDK6 inhibitors useful in the treatment of diseases.<br>References Li, X., et al.: PCT Int. Appl., WO 2014183520 A1 20141120 (2014)<br></p>

<p>Applications 1,2-Dimethylpiperazine (cas# 25057-77-6) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Miyamoto, T., et al.: J. Med. Chem., 33, 1645 (1990),<br></p>

<p>Applications N-[5-(4-Bromophenyl)-6-[2-(2-pyrimidinyloxy)ethoxy]-4-pyrimidinyl]-N'-propyl-sulfamide is a degradation product of Macitentan (M105005).<br>References Thummar, Mohit, et al.: Chromatographia, 81(3), 525-531 (2018)<br></p>

<p>Applications 1-Ethyl-3-piperidinone Hydrochloride used in preparation of Aminoimidazoles.<br>References Sabbasani, Venkata R., et al.: Angewandte Chemie, 58, 18913-18917 (2019);<br></p>

<p>Applications 6-chloro[1,2,4]triazolo[4,3-b]pyridazin-3(2H)-one (cas# 33050-32-7) is a useful research chemical.<br></p>

<p>Applications (S)-(-)-1-Amino-2-(methoxymethyl)pyrrolidine is a disubstituted pyrrolidine. (S)-(-)-1-Amino-2-(methoxymethyl)pyrrolidine undergoes condensation reactions with carbonyl compounds to produce hydrazones which are useful for highly enantioselective synthesis.<br>References Enders, D. et al.: Tetrahed. Lett., 2, 191 (1977); Zakharova, V. et al.: Zeitsch. Naturforsch. B Chem. Sci., 61, 464 ·2006);<br></p>

<p>Applications 3-(Triethoxysilyl)propyl 2-((4-amino-5-hydrazinyl-4H-1,2,4-triazol-3-yl)thio)propanoate is a useful reagent for organic reactions.<br></p>

<p>Applications (7H-Pyrazolo[3,4-b]pyridin-5-yl)methanamine Hydrochloride is a useful research chemical.<br></p>

<p>Applications 1-(Trimethylsilyl)-1H-benzotriazole (cas# 43183-36-4) is a useful research chemical.<br></p>

<p>Stability Moisture Sensitive<br>Applications Pentathiodiphosphorus(V) Acid P,P′-Bis(pyridinium betaine) is an thionating agent used in synthetic chemistry.<br>References Bergman, J., et al.: J. Org. Chem., 76, 1546 (2011);<br></p>

<p>Applications 2,4-Dinitro-1H-imidazole is a reagent that can be used to synthesize (S)-PA 824 (P122500), which is a novel anti-tuberculosis drug.<br>References Diacon, A.H. et al.: Antimicrob. Anents Chemother., 54, 3402 (2010); Dogra, M. et al.: Br. J. Pharmacol., 162, 226 (2010); Ginsberg, A.M. et al.: Antimicrob. Agents Chemother., 53, 3720 (2009);<br></p>

<p>Applications Piperazine-N,N'-bis(2-ethanesulfonic Acid)-d18 (CAS# 352534-95-3) is a useful isotopically labeled research compound.<br></p>

<p>Applications 3-Chloro-5-(trifluoromethyl)-2-pyridinecarbonitrile<br></p>

<p>Applications 5-Cyclohexyl-2-piperidinecarboxylic Acid is a compound useful in organic synthesis.<br></p>

<p>Applications 4-Oxo-2,2,6,6-tetramethylpiperidine-d17 (CAS# 52168-48-6) is a useful isotopically labeled research compound.<br></p>

<p>Applications 5-(2-Pyridyl)isoxazole-3-carboxylic Acid is a useful reagent for the preparation of isoxazoles for treatment of neurological disease.<br>References Wrona, I., et al.: PCT Int. Appl. (2019), WO 2019209962 A1<br></p>

<p>Applications Intermediate in the preparation of various biological inhibitors.<br>References Chonan, T., et al.: Bioorg. Med. Chem. Lett., 19, 6645 (2009), Bunnage, M., et al.: J. Med. Chem., 50, 6095 (2007),<br></p>

<p>Applications 2H-1,2,3-triazole-4-carboxylic acid (cas# 573714-78-0) is a useful research chemical.<br></p>

<p>Applications 4-Chloro-6-ethylthieno[2,3-d]pyrimidine is a useful intermediate for organic synthesis.<br>References Ostrynska, O. V., et al.: Eur. J. Med. Chem., 115, 148 (2016); Ram, V. J., et al.: J. Heterocycl. Chem., 1277 (1981); Sharma, C., et al.: E-J. Chem., 7, 655 (2010)<br></p>

<p>Applications 1,2-benzisoxazol-3-amine (cas# 36216-80-5) is a useful research chemical.<br></p>

<p>Applications 4-Hydroxypiperidine-3,3,4,5,5-d5-N-t-BOC (CAS# 1523606-18-9) is a useful isotopically labeled research compound.<br></p>

<p>Applications An intermediate in the preparation of serotonin 5-HT2a receptor antagonists<br>References Ullrich, T., et al.: Bioorg. Med. Chem., 8, 2427 (2000),<br></p>

<p>Applications 3,5-Dimethylpyrazole-4-boronic acid, Hydrochloride is a useful research chemical for organic synthesis and other chemical processes.<br>References Jones, A., et al.: From PCT Int. Appl. (2016), WO 2016046530 A1 20160331<br></p>

<p>Applications 4-{[5-(trifluoromethyl)pyridin-2-yl]amino}butanoic acid (cas# 923121-46-4) is a useful research chemical.<br></p>

<p>Applications 3-(1,4,5,6-tetrahydro-2-pyrimidinyl)​-phenol-d6 is labelled 3-(1,4,5,6-tetrahydro-2-pyrimidinyl)​-phenol (T293810) which is a useful synthetic intermediate.<br></p>

<p>Applications 4-(3,5-Dimethylpyrazol-1-yl)phenylboronic acid, pinacol ester<br></p>

<p>Applications An intermediate in the production of Zolpidem metabolites<br>References Klupsch, F., et al.: Chem. Pharm. Bull., 54, 1318 (2006),<br></p>

<p>Applications 3-Hydroxypyrrolidine, HCl<br></p>

<p>Stability Light Sensitive<br>Applications 5-Bromo-2-iodopyridine is used to prepare substituted (pyridin-​3-​yl)​phenyloxazolidinones as antibacterial agents. It is also used to synthesize indole-​based bisamidine antibiotics.<br>References Reck, F., et al.: J. Med. Chem., 50, 4868 (2007); Williams, J., et al.: Bioorg. Med. Chem., 21, 7790 (2013)<br></p>

<p>Applications 5-(4’-Benzyloxyphenyl)-2-oxazolidone (cas# 88693-98-5) is a compound useful in organic synthesis.<br></p>

<p>Applications Methyl 1-[(2-Fluorophenyl)methyl]pyrazolo[3,4-b]pyridine-3-carboximidate is a useful reactant to study metabolites of orally active NO-independent pyrazolopyridine stimulators of soluble guanylate cyclase.<br>References Straub, A., et al.: Bioorg. Med. Chem., 10, 1711 (2002);<br></p>

<p>Applications Piperonyl Methoxyethyl Ether-d3 is the isotope labelled analog of Piperonyl Methoxyethyl Ether (P490475); a selective inhibitor of the cytochrome P450-dependent monooxygenase from the housefly.<br>References Motoyama, N., et al.: Rev. Pestic. Toxicol., 1, 173 (1991)<br></p>

<p>Applications 2-Chloro-4-(trifluoromethyl)pyrimidine (cas# 33034-67-2) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 2-Amino-5-bromopyrazine (cas# 59489-71-3) is a compound useful in organic synthesis.<br>References Shi, Z., et al.: J. Med. Chem., 51, 3684 (2008), Onda, K., et al.: Bioorg. Med. Chem., 16, 5452 (2008),<br></p>

<p>Applications 3-Hydroxypicolinic acid<br></p>

<p>Applications A labelled imidazole, a versatile heterocycle used in the preparation of various biologically active compounds such as the amino acid histidine and is present in many antifungal medication. It is also used extensively as a corrosion inhibitor on transition metals such as copper.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Arispe, N. et al.: Biophys. J., 95, 4879 (2008); Troesken, E.R. et al.: Endo. Res., 30, 387 (2004); Otmacic Curkovic, H. et al.: Corr. Sci., 51, 2342 (2009);<br></p>

<p>Applications N-(2-(2-Nitro-1H-imidazol-1-yl)ethyl)acrylamide is a useful synthesis intermediate.<br></p>

<p>Applications 6-bromo-5-iodopyridine-3-carboxylic acid (cas# 1200130-82-0) is a useful research chemical.<br></p>

<p>Applications An intermediate of Rosuvastatin (R700500).<br></p>

<p>Applications Diethyl Pyridine-2,3-dicarboxylate is a useful reagent in preparation of herbicides.<br>References Doehner, R.: Eur. Pat. Appl. (1988), EP 254951 A2 19880203.<br></p>