Heterociclos con nitrógeno (N)

<p>Stability Hygroscopic<br>Applications Methyl 4-Oxopiperidine-3-carboxylate Hydrochloride (cas# 71486-53-8) is a useful research chemical.<br></p>

<p>Applications α,α,1,6-Tetramethyl-3-piperidinemethanol, has shown to be able to facilitate new modes of reactivity via constrictive binding in a supramol.-assembly-catalyzed aza-Prins cyclization.<br>References Kaphan, D. M., et al.: Journal of the American Chemical Society, Vol. 137, P: 9202-9205 (2015);<br></p>

<p>Applications 2,6-Dibromo-3-fluoropyridine is a useful reagent for making GLP-1 receptor agonists.<br>References Aspnes, G. E., et al.: PCT Int. Appl. (2019), WO 2019239371 A1<br></p>

<p>Applications 3,4-Dihydro-4-hydroxy-1(2H)-pyridinecarboxylic Acid Ethyl Ester is a synthetic intermediate/reactant in the synthesis of streptazolin.<br>References Kozikowski, A., Park, P.: J. Org. Chem., 55, 4668 (1990);<br></p>

<p>Applications 2,6-Piperazinedione Hydrochloride is a synthetic intermediate that can be used to prepare anti-inflammatory or antitumor compounds. 2,6-Piperazinedione Hydrochloride is also applicable for the synthesis of 4-succinamoyl-piperazine-2,6-dione derivatives, which are compounds with analgesic properties.<br>References Shvedaite, I. P., et al.: Pharmaceut Chem J 33, 313 (1999); Shvedaite, I. P. and Shimkyavichene, V. I.: Pharmaceut Chem J  33, 359 (1999); Svedaite, I.: Chemija 18, 50 (2007)<br></p>

<p>Applications 4-PIPERAZIN-1-YL-QUINOLINE DIHYDROCHLORIDE (cas# 1350361-89-5) is a useful research chemical.<br></p>

<p>Applications 2-(Methylsulfonyl)-2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole is a useful reagent for developing dipeptidyl peptidase IV inhibitors for treatment or prevention of diabetes.<br>References Nakajima, Y., et al.: J. Mol. Cell Cardiol., 129, 257-265 (2019)<br></p>

<p>Applications 3-Bromo-6,7-dihydro-5H-cyclopenta[b]pyridin-5-one is a useful synthetic intermediate.<br></p>

<p>Stability Moisture Sensitive<br>Applications Contains approximately 12% dichloromethane and 8% ethyl acetate<br></p>

<p>Applications 2,5-Di-4-pyridinylpyrazine is a compound used in the preparation of isonicotonic acid derivatives used in the chemotherapy of tuberculosis.<br>References Cymerman-Craig, J., et al.: J Chem Soc., 4315-20 (1955);<br></p>

<p>Applications 1-(2-bromophenyl)piperazine (cas# 1011-13-8) is a useful research chemical.<br></p>

<p>Applications 1-(4-Hydroxyphenyl)piperidin-2-one (cas# 79557-03-2) is a compound useful in organic synthesis.<br></p>

<p>Applications 1-Isopropyl-d7-piperazine (CAS# 2089679-76-3) is a useful isotopically labeled research compound.<br></p>

<p>Applications tert-Butyl 4-(3-hydroxypropyl)piperidine-1-carboxylate is a reagent in the preparation of 1-alkyloxy-2-methoxy-4-nitrobenzene fragments: potent human glutaminyl cyclase inhibitors<br>References Hoang, Van-Hai, et al.: J. of Med. Chem., 60(6), 2573-2590 (2017)<br></p>

<p>Applications 1-(2,6-Dichlorophenyl)piperazine-d8 Hydrochloride is the isotope analog of 1-(2,6-Dichlorophenyl)piperazine Hydrochloride. 1-(2,6-Dichlorophenyl)piperazine Hydrochloride is used in the preparation of pyrazolopyrimidones and pyrazolopyridones as tankyrase inhibitors which are useful in the treatment of cancer.<br>References Feng, J., et al.: PCT Int. Appl., 2013:1906020 (2013)<br></p>

<p>Stability Light Sensitive<br>Applications A reagent for the determination of aldehydes and other reactive chemicals.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dickinson, R.G. and Jacobsen,N.W. : Chem. Commun., 1719, (1970), Del Nozal, M.J. et al.: J. Liq. Chromatography, 16, 1105 (1993),<br></p>

<p>Applications 2-chloro-1H-benzimidazole (cas# 4857-06-1) is a useful research chemical.<br></p>

<p>Applications 5-[2-(trifluoromethyl)phenyl]-1,2-oxazole-4-carboxylic acid (cas# 1003561-80-5) is a useful research chemical.<br></p>

<p>Applications Reagent used in Guanidino transfers.<br></p>

<p>Applications 5-Hydroxy-4,6-dimethyl-3-pyridinemethanol is used in the study of sphingosine-1-phosphate is a major chemoattractant and stem cell mobilization factor.<br>References Ratajczak, M.Z., et al.: Leukemia, 24, 976 (2010)<br></p>

<p>Applications 4-Ethylpyridine is a general chemical reagent used in the synthesis of substituted pyridines as well as diverse azacyclic compounds.<br>References Gandhamsetty, N. et al.: J. Am. Chem. Soc., 137, 15176 (2015); Chen, X. et al.: J. Coord. Chem., 68, 2835 (2015);<br></p>

<p>Applications 5-Nitro-2-(propylthio)pyrimidin-4-ol is an intermediate used in the synthesis of 4-Chloro-5-nitro-2-(propylthio)pyrimidine (C374095), which is an impurity of the drug Ticagrelor (T437700), the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Ticagrelor is used in the treatment of acute coronary syndromes (ACS).<br>References Matetzky, S., et al.: Circulation, 109, 3171 (2004), Bassand, J., et al.: Eur. Heart J., 28, 1598 (2007), Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2007)<br></p>

<p>Applications 2-Aminopyrimidine-5-boronic Acid Pinacol Ester is used in the preparation of phosphoinositide-3-kinases (PI3K) inhibitors.<br>References Burger, M.T. et al.: ACS Med. Chem. Lett., 2, 774 (2011); Heffron, T.P. et al.: J. Med. Chdem., 55, 8007 (2012);<br></p>

<p>Applications 4-Bromo-2-(methoxymethyl)pyridine (cas# 864412-04-4) is a useful research chemical.<br></p>

<p>Applications Ethyl-2-ethoxy-1-[[(2'-cyanobiphenyl-4-yl) methyl] benzimidazole]-7-carboxylate<br></p>

<p>Applications 2-(5-Ethylpyridin-2-yl)prop-2-en-1-ol is a key intermediate in the synthesis of pioglitazone hydrochloride.<br>References Mohanty, S., et al.: Org. Process Res. Dev., 18, 168 (2014)<br></p>

<p>Applications 3-Bromopyridine N-Oxide (cas# 2402-97-3) is a compound useful in organic synthesis.<br></p>

<p>Applications {2-[(Pyridin-4-ylmethyl)thio]-1,3-thiazol-4-yl}acetic acid (cas# 1040631-48-8) is a useful research chemical.<br></p>

<p>Applications (R)-3-Aminopiperidine-2-one<br></p>

<p>Applications 1-isobutyl-1H-pyrazole-3-carboxylic acid (cas# 1006493-64-6) is a useful research chemical.<br></p>

<p>Applications 2,5-Diamino-4,6-dichloropyrimidine is a useful reagent for the preparation of Abacavir impurities, carbocyclic and hexenopyranosy nucleosides.<br>References Satyanarayana, G. V., et al.: Pharma Chemica, 7, 90 (2015)<br></p>

<p>Applications 3-(PIPERAZIN-1-YL)-1,2-BENZISOXAZOLE (cas# 87691-89-2) is a useful research chemical.<br></p>

<p>Applications N-3-Piperidinylcarbamic Acid 1,1-Dimethylethyl Ester is used in the synthesis of highly selective spleen tyrosine kinase inhibitors. Also used in the synthesis of a potent NHE1 inhibitor displaying cardioprotective effects.<br>References Lucas, M. et al.: J. Med. Chem., 55, 10414 (2012); Huber, J. et al.: J. Med. Chem., 55, 7114 (2012);<br></p>

<p>Applications Succinimidyl Nervonate (cas# 191354-88-8) is a compound useful in organic synthesis.<br></p>

<p>Applications 6-Bromopicolinic acid<br></p>

<p>Applications 2-[4-(3-Pyrrolidinyl)1,3-thiazol-2yl]guanidine is a reagent which is used in biological studies as antiulcer agent.<br>References Gupta, S., et al.: J. Chem. Info. Comp. Sci, 39, 272 (1999)<br></p>

<p>Applications 5-pyridin-3-ylfuran-2-carboxylic acid (cas# 56632-46-3) is a useful research chemical.<br></p>

<p>Applications 5-Bromo-6-chloropyridine-3-sulfonyl Chloride (cas# 216394-05-7) is a compound useful in organic synthesis.<br></p>

<p>Applications 4-(azetidin-3-yl)-4H-1,2,4-triazole (cas# 1495939-85-9) is a useful research chemical.<br></p>

<p>Applications 1,​2-​Dihydro-​2-​thioxo-​6-​(trifluoromethyl)​-4-​pyrimidinecarboxylic Acid is a useful synthetic intermediate.<br></p>

<p>Applications 2-Fluoropyridine acts as a reagent in the synthesis of aminopyrimidines with antimicrobial and antifungal properties.<br>References Hedidi, M., et al.: Eur. J. Org. Chem., 39, 5903 (2017)<br></p>

<p>Applications (3E)-4-(5-Ethoxy-3-pyridinyl)-3-buten-1-ol is an intermediate in the synthesis of TC 2559 Fumarate (T012005), which is a partial agonist for AChR α4β2.<br></p>

<p>Applications 1,3-Dimethyl-5-pyrazolone (cas# 2749-59-9) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-(Ethylthio)-1H-benzimidazole is the active substance or the active ingredient in the synthesis of the drug Metaprot. Performs a transplacental function: daily administration of bemithyl (20 mg/kg) from 6 th to 16 th day of pregnancy in female rats led to the decrease in fetal death after the implantation and increased fetal body weight.<br>References Kibal'chich, D. A., et al.: Eksperimental'naya i Klinicheskaya Farmakologiya, 74, 30 (2011); Bugaeva, L. I., et al.: Eksperimental'naya i Klinicheskaya Farmakologiya, 70, 40 (2007).<br></p>

<p>Applications An intermediate in the preparation of serotonin 5-HT2a receptor antagonists<br>References Ullrich, T., et al.: Bioorg. Med. Chem., 8, 2427 (2000),<br></p>

<p>Applications 2-Chloro-4-(trifluoromethyl)pyrimidine (cas# 33034-67-2) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Pyridine-15N, is the labeled analogue of Pyridine (P991280), a basic six-membered heterocyclic ring. Pyridine is a base structure present in many biologically active compounds like the vitamins niacin and pyridoxal. Pyridine is used in dehalogenation reactions and can be used as a base in condensation reactions.<br>References Egyed, J. et al.: Bull. Soc. Chim. Fra., 11, 3014 (1973); Li, Y. et al.: Wuli HUa. Xueb., 14, 1048 (1998);<br></p>

<p>Stability Moisture Sensitive, Hygroscopic<br>Applications 1,2-dimethyl-1H-imidazole-4-sulfonyl chloride (cas# 137049-02-6) is a useful research chemical.<br></p>

<p>Applications 3-Piperidinesulfonic Acid is an isomer of piperidine-4-sulfonic acid, a new specific GABA agonist.<br>References Krogsgaard-Larsen, P., et al.: J. Neurochem., 34, 756 (1980)<br></p>

<p>Applications 6-bromo-5-iodopyridine-3-carboxylic acid (cas# 1200130-82-0) is a useful research chemical.<br></p>