Heterociclos con nitrógeno (N)

<p>Applications 2-Amino-5-bromopyrazine (cas# 59489-71-3) is a compound useful in organic synthesis.<br>References Shi, Z., et al.: J. Med. Chem., 51, 3684 (2008), Onda, K., et al.: Bioorg. Med. Chem., 16, 5452 (2008),<br></p>

<p>Applications Piperonyl Methoxyethyl Ether-d3 is the isotope labelled analog of Piperonyl Methoxyethyl Ether (P490475); a selective inhibitor of the cytochrome P450-dependent monooxygenase from the housefly.<br>References Motoyama, N., et al.: Rev. Pestic. Toxicol., 1, 173 (1991)<br></p>

<p>Applications 5-(4’-Benzyloxyphenyl)-2-oxazolidone (cas# 88693-98-5) is a compound useful in organic synthesis.<br></p>

<p>Stability Light Sensitive<br>Applications 5-Bromo-2-iodopyridine is used to prepare substituted (pyridin-​3-​yl)​phenyloxazolidinones as antibacterial agents. It is also used to synthesize indole-​based bisamidine antibiotics.<br>References Reck, F., et al.: J. Med. Chem., 50, 4868 (2007); Williams, J., et al.: Bioorg. Med. Chem., 21, 7790 (2013)<br></p>

<p>Applications 4-Hydroxythieno[2,3-d]pyrimidine (cas# 14080-50-3) is a compound useful in organic synthesis.<br></p>

<p>Applications 1-(Formamidomethyl)-1H-benzotriazole is a useful reagent for the synthesis 1-​isocyanomethyl azoles and related compounds.<br>References Saikachi, H., et al.: Chem. Pharm. Bull., 31, 723 (1983)<br></p>

<p>Stability Moisture Sensitive<br>Applications N-Acetoxysuccinimide (cas# 14464-29-0) is a useful research chemical.<br></p>

<p>Applications α-Butyl-α-(2,4-dichlorophenyl)-4H-1,2,4-triazole-4-ethanol is a useful synthetic intermediate.<br></p>

<p>Applications 4-(3,5-Dimethylpyrazol-1-yl)phenylboronic acid, pinacol ester<br></p>

<p>Applications 3-(1,4,5,6-tetrahydro-2-pyrimidinyl)​-phenol-d6 is labelled 3-(1,4,5,6-tetrahydro-2-pyrimidinyl)​-phenol (T293810) which is a useful synthetic intermediate.<br></p>

<p>Applications 4-{[5-(trifluoromethyl)pyridin-2-yl]amino}butanoic acid (cas# 923121-46-4) is a useful research chemical.<br></p>

<p>Applications 3,5-Dimethylpyrazole-4-boronic acid, Hydrochloride is a useful research chemical for organic synthesis and other chemical processes.<br>References Jones, A., et al.: From PCT Int. Appl. (2016), WO 2016046530 A1 20160331<br></p>

<p>Applications 3-tert-Butylthio-2-cyanopyridine (cas# 178811-40-0) is a compound useful in organic synthesis.<br></p>

<p>Applications 6-Chloropyridine-2-carboxylic Acid is an intermediate of Sorafenib b(S676850), a multiple kinase inhibitor targeting both RAF kinase and receptor tyrosine kinases that promote angiogensis. Antineoplastic.<br>References Richly, H., et al.: Int. J. Clin. Pharmacol. Ther., 41, 620 (2003); Khire, U.R., et al.: Bioorg. Med. Chem. Lett., 14, 783 (2004); Wilhelm, S.M., et al.: Cancer Res., 64, 7099 (2004); Rini, B.I., et al.: Expert Opin. Pharmacother., 7, 453 (2006)<br></p>

<p>Applications 5-Chloro-2,3-difluoropyridine is a 2,3,5-trihalopyridine used in the preparation of the herbicides and pesticides such as chodinafop-propargyl.<br>References Chen, Q. et al.: Jin. Huag. Zhong., 35, 35 (2005); Feng, C. et al.: Nonyao, 46, 793 (2007);<br></p>

<p>Applications 1,2-benzisoxazol-3-amine (cas# 36216-80-5) is a useful research chemical.<br></p>

<p>Applications N-[[(2S)-1-Ethyl-2-pyrrolidinyl]methyl]carbamic Acid 1,1-Dimethylethyl Ester is an building block in the synthesis of Amisulpride (A633250) related compound.<br></p>

<p>Applications 2-Amino-4-chloro-3-nitropyridine (cas# 6980-08-1) is a compound useful in organic synthesis.<br>References Bavetsias, V., et al.: Bioorg. Med. Chem. Lett., 17, 6567 (2007), Niculescu-Duvaz, D., et al.: J. Med. Chem., 52, 2255 (2009),<br></p>

<p>Applications 4-ethyl-4H-furo[3,2-b]pyrrole-5-carboxylic acid (cas# 80709-74-6) is a useful research chemical.<br></p>

<p>Applications tert-Butyl-7-[4-(4-fluorophenyl)-6-isopropyl-2-mesylaminopyrimidin-5-yl]-(3R,5S)-isopropylidine-(E)-6-heptenoate (cas# 371775-73-4) is a compound useful in organic synthesis.<br></p>

<p>Applications Oxazolidine-4-carboxylic acid hydrochloride (cas# 162285-30-5) is a useful research chemical.<br></p>

<p>Applications Intermediate in the preparation of various biological inhibitors.<br>References Chonan, T., et al.: Bioorg. Med. Chem. Lett., 19, 6645 (2009), Bunnage, M., et al.: J. Med. Chem., 50, 6095 (2007),<br></p>

<p>Applications 5-(2-Pyridyl)isoxazole-3-carboxylic Acid is a useful reagent for the preparation of isoxazoles for treatment of neurological disease.<br>References Wrona, I., et al.: PCT Int. Appl. (2019), WO 2019209962 A1<br></p>

<p>Applications 3-Hydroxypiperidine is used as a reagent to synthesize trisubstituted ureas, compounds that act as thrombin receptor (PAR-1) antagonists. 3-Hydroxypiperidine is also a metabolite of Piperidine (P479985), Piperidine is an organic heterocyclic amine widely used as building block and reagent in the synthesis of organic compounds including pharmaceuticals.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Barrow, J., et al.: Bioorg. Med. Chem. Lett., 11, 2691 (2001); Reshmi, S.K., et al.: J. Med. Plant. Res., 4, 1535 (2010); Wiles, J.A., et al.: J. Med. Chem., 54, 3418 (2011);<br></p>

<p>Applications A pyrimidine derivative as inhibitor of Streptococcus faecium, Lactobacillus casei, and Pediococcus cerevisiae.<br>References Coats, E.A., et al.: Eur. J. Med. Chem., 14, 261 (1979),<br></p>

<p>Applications 5-Cyclohexyl-2-piperidinecarboxylic Acid is a compound useful in organic synthesis.<br></p>

<p>Applications 3-Chloro-5-(trifluoromethyl)-2-pyridinecarbonitrile<br></p>

<p>Applications 5-(3-fluorophenyl)-4H-1,2,4-triazol-3-amine (cas# 502685-67-8) is a useful research chemical.<br></p>

<p>Applications 5-Methyl-2(1H)-pyridinone-d6 is a reagent used in the preparation of substituted N-aryl pyridinones as fibrotic inhibitors.<br></p>

<p>Applications Urazole derivative.<br></p>

<p>Applications 1-(Trimethylsilyl)-1H-benzotriazole (cas# 43183-36-4) is a useful research chemical.<br></p>

<p>Applications 4-Amino-2,2,6,6-tetramethylpiperidine-d17; 1-15N-1-oxyl (CAS# 97461-87-5) is a useful isotopically labeled research compound that is used in various experiments, such as, synthesis of two cysteine-specific spin labels.<br>References Wu,G. J. Label. Compd.Radiopharm., 12,1173-1181,(1995);<br></p>

<p>Applications 2-Chloro-5-nitropyrimidin-4-ol is an intermediate used in the synthesis of 4-Chloro-5-nitro-2-(propylthio)pyrimidine (C374095), which is an impurity of the drug Ticagrelor (T437700), the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Ticagrelor is used in the treatment of acute coronary syndromes (ACS).<br>References Matetzky, S., et al.: Circulation, 109, 3171 (2004), Bassand, J., et al.: Eur. Heart J., 28, 1598 (2007), Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2007)<br></p>

<p>Applications 6-Methylpyridine-3-amine, is a heterocyclic building block used in the manufacture of various pharmaceutical compounds. It can be used for the synthesis of 2-aminoquinazoline derivatives, as a novel class of metabotropic glutamate receptor 5 negative allosteric modulators (mGluR5), leading toward a drug candidate for the treatment of l-DOPA induced dyskinesia.<br>References Kubas, H., et al.: Bioorg. Med. Chem. Lett., 23 (16), 4493 (2013);<br></p>

<p>Applications (7H-Pyrazolo[3,4-b]pyridin-5-yl)methanamine Hydrochloride is a useful research chemical.<br></p>

<p>Applications 3-(Triethoxysilyl)propyl 2-((4-amino-5-hydrazinyl-4H-1,2,4-triazol-3-yl)thio)propanoate is a useful reagent for organic reactions.<br></p>

<p>Applications 6,​8-​Dibromo-​3,​4-​dihydro-​3,​3-​bis(1-​pyrrolidinylmethyl)​-2H-1-benzopyran-4-ol is a useful synthetic reagent.<br></p>

<p>Applications 1,2-Dimethylpiperazine (cas# 25057-77-6) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Miyamoto, T., et al.: J. Med. Chem., 33, 1645 (1990),<br></p>

<p>Applications 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido-[2,3-d]pyrimidin-7(8H)-one is used to prepare pyridino[2,3-d]pyrimidin-7(8H)-one derivatives as CDK4 and/or CDK6 inhibitors useful in the treatment of diseases.<br>References Li, X., et al.: PCT Int. Appl., WO 2014183520 A1 20141120 (2014)<br></p>

<p>Applications 4-(ethylamino)-6-(isopropylamino)-1,3,5-triazine-2-thiol (cas# 5498-17-9) is a useful research chemical.<br></p>

<p>Stability Hygroscopic<br>Applications 6-Methylpyridine-3-boronic Acid Hydrochloride Hydrate is the Hydrochloride of M326565, which is used in the preparation of various biologically active compound such as phosphoinositide-3-kinases (PI3K) and c-jun N-terminal kinase (JNK) inhibitors.<br>References Smith, A.L. et al.: J. Med. Chem., 55, 5188 (2012); Perry, B. et al.: Bioorg. Med. Chem. Lett., 18, 4700 (2008); Chambers, J. et al.: ACS Chem. Neurosci., 2, 198 (2011);<br></p>

<p>Applications 4-Ethyl-1,3-Oxazolidin-2-One (cas# 16112-60-0) is a useful research chemical.<br></p>