Heterociclos con nitrógeno (N)

<p>Applications 4-Chloro-N-(methyl-d3)pyridine-2-carboxamide (cas# 1189858-48-7) is a compound useful in organic synthesis.<br></p>

<p>Applications Ethyl 2-pyrimidinecarboxylate<br></p>

<p>Applications A pyrazole derivative used as an intermediate in the preparation of herbicides.<br></p>

<p>Applications 2-​(Methoxy-​d3)​-​3-​(1-​methylethyl)​pyrazine is a useful compound in the study of isotope effect in gas liquid chromatography separation of deuterated and nondeuterated compounds using ionic liquid stationary phases.<br>References Schmarr, H., et al.: J. Chromatogr. A., 1270, 310 (2012);<br></p>

<p>Applications 5-Bromo-6-chloropyridine-3-sulfonyl Chloride (cas# 216394-05-7) is a compound useful in organic synthesis.<br></p>

<p>Applications 6-Methyl-3-pyridineacetonitrile is a reactant used in the preparation of pyrazolopyrimidine derivatives as agents for treatment of autoimmune diseases and orally active corticotropin-releasing factor receptor antagonists.<br>References Chen, C. et al.: J. Med. Chem., 47, 4787 (2004)<br></p>

<p>Applications The preparation and incorporation of 2-[2-[2-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]acetic Acid into the bilayers of liposomal constructs used for immunization with synthetic peptides.<br>References Frisch, B., et al.: Bioconjugate Chem., 7, 180-186 (1996)<br></p>

<p>Applications 3-(PIPERAZIN-1-YL)-1,2-BENZISOXAZOLE (cas# 87691-89-2) is a useful research chemical.<br></p>

<p>Applications 3-Cyano-4-(trifluoromethyl)pyridine<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 5-Bromo-3-methylpicolinic Acid is used to prepare oxazine derivatives as BACE inhibitors useful in treatment of neurological disorders.<br>References Badiger, S., et al.: PCT Int. Appl., WO 2011009943 A1 20110127 (2011); Tintelnot-Blomley, M., et al.: PCT Int. Appl., WO 2011080176 A1 20110707 (2011)<br></p>

<p>Applications Dimethylhydrazone-1-methyl-4-piperidinone is an intermediate in the synthesis of α-Meprodine Hydrochloride (M224950), which is a narcotic analgesic. An analogue of Proline (P755300).<br>References Iorio, M.A., et al.: J. Med. Chem., 20, 309 (1977),<br></p>

<p>Applications 3-FLUOROPYRAZIN-2-AMINE (cas# 1206523-95-6) is a useful research chemical.<br></p>

<p>Applications Used for preparation of phthalide derivatives for treatment of diabetes.<br></p>

<p>Applications 5-pyridin-3-ylfuran-2-carboxylic acid (cas# 56632-46-3) is a useful research chemical.<br></p>

<p>Applications The hydrochloride salt of 1-(4-Fluoro-benzyl)-2-piperazin-1-yl-1H-benzoimidazole (CAS:142617-98-9) which is related to Astemizole(A790030) a histamine H1-receptor antagonist.<br>References Drugs, 28, 38 (1984), Al-Obaid, A.M., et al.: Anal. Profiles Drug Subs., 20, 173 (1991), Ishikawa, M., et al.: Biol. Pharm. Bull., 23, 112 (2000)<br></p>

<p>Applications A chiral fluoro-pyridine derivative used in the preparation of dihydropyrrolopyrimidinone derivatives for use as MARK inhibitors.<br></p>

<p>Applications 2,4,4-Trimethyl-2-oxazoline is a useful building block and has been used in the preparation of imides by ring opening of heterocycles by reactions of acyl palladium species.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Perrone, S.; et al.: Tetrahedron, 70, 6938 (2014).<br></p>

<p>Applications 1,3,5-Tris(3-chloro-2-hydroxypropyl)-1,3,5-triazine-2,4,6(1H,3H,5H)-trione-d15 is an intermediate for the synthesis of Triglycidyl Isocyanurate-d15 (T793817). Isotope labelled Triglycidyl isocyanurate is a reagent used in the synthesis of N-Benzyl Metaxalone (B285000), which is a muscle relaxant used to relax muscles and relieve pain.<br>References Toth, P.E., et al.: Clin. Ther., 26, 1355 (2004)<br></p>

<p>Applications 5-Bromo-2-chloro-3-nitropyridine (cas# 67443-38-3) is a compound useful in organic synthesis.<br></p>

<p>Stability Hygroscopic<br>Applications 2-Bromo-5-fluoropyridine-4-boronic acid<br></p>

<p>Applications 3-Bromo-2-hydroxypyridine is used in the synthesis of pyrazolopyridines as γ-secratase modulators.<br>References Qin, J. et al.: ACS Med. Chem. Lett., 2, 471 (2011);<br></p>

<p>Applications 4-Nitro-1,2,3-triazole is a highly impact sensitive and explosive material.<br>References Politzer, P. et al.: Int. J. Quant. Chem., 61, 389 (1997);<br></p>

<p>Applications N-(3-{[2-chloro-5-(trifluoromethyl)pyrimidin-4-yl]amino}phenyl)prop-2-enamide (cas# 1374507-25-1) is a useful research chemical.<br></p>

<p>Applications 2-(2-((6-(2-Cyanophenoxy)pyrimidin-4-yl)oxy)phenyl)-2-oxoacetic Acid Methyl Ester is an intermediate in the synthesis of (Z)-Azoxystrobin (A965155), a fungicide that inhibits mitochondrial respiration by blocking electron transfer between cytochromes b and c1<br>References Smalling, K., et al.: Environ. Toxicol. Chem., 29, 2593 (2010), Lu, X., et al.: Phytopathol., 100, 1162 (2010), Schafer, R., et al.: Environ. Sci. Technol., 45, 1665 (2011),<br></p>

<p>Applications 2-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)pyridine, is a building block used in the synthesis of chemical compounds.<br></p>

<p>Applications 4-(azetidin-3-yl)-4H-1,2,4-triazole (cas# 1495939-85-9) is a useful research chemical.<br></p>

<p>Applications 2-Hydrazino-1H-1,3-benzimidazole<br></p>

<p>Applications α-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-4-hydroxybenzeneacetic acid is used in the preparation of Cefoperazone an antibiotic.<br>References Xu, Y., et al.: Zhongguo Yaoke Daxue Xuebao, 28, 264 (1997);<br></p>

<p>Applications Piperazine-N,N'-bis(2-ethanesulfonic Acid)-d18 (CAS# 352534-95-3) is a useful isotopically labeled research compound.<br></p>

<p>Applications 4-Amino-2,6-dichloropyridine (cas# 2587-02-2) is a compound useful in organic synthesis.<br>References Altenbach, R., et al.: J. Med. Chem., 51, 6571 (2008), Namba, K., et al.: Bioorg. Med. Chem., 16, 6131 (2008),<br></p>

<p>Applications 2-Fluoropyridine acts as a reagent in the synthesis of aminopyrimidines with antimicrobial and antifungal properties.<br>References Hedidi, M., et al.: Eur. J. Org. Chem., 39, 5903 (2017)<br></p>

<p>Applications (3E)-4-(5-Ethoxy-3-pyridinyl)-3-buten-1-ol is an intermediate in the synthesis of TC 2559 Fumarate (T012005), which is a partial agonist for AChR α4β2.<br></p>

<p>Applications 4-Oxo-2,2,6,6-tetramethylpiperidine-d17 (CAS# 52168-48-6) is a useful isotopically labeled research compound.<br></p>

<p>Applications 4-Chloro-6-ethylthieno[2,3-d]pyrimidine is a useful intermediate for organic synthesis.<br>References Ostrynska, O. V., et al.: Eur. J. Med. Chem., 115, 148 (2016); Ram, V. J., et al.: J. Heterocycl. Chem., 1277 (1981); Sharma, C., et al.: E-J. Chem., 7, 655 (2010)<br></p>

<p>Applications 1,3-Dimethyl-5-pyrazolone (cas# 2749-59-9) is a compound useful in organic synthesis.<br></p>

<p>Applications 3-Chloropyridine-d4 (CAS# 1001003-95-7) is a useful isotopically labeled research compound.<br></p>

<p>Applications 2-(Ethylthio)-1H-benzimidazole is the active substance or the active ingredient in the synthesis of the drug Metaprot. Performs a transplacental function: daily administration of bemithyl (20 mg/kg) from 6 th to 16 th day of pregnancy in female rats led to the decrease in fetal death after the implantation and increased fetal body weight.<br>References Kibal'chich, D. A., et al.: Eksperimental'naya i Klinicheskaya Farmakologiya, 74, 30 (2011); Bugaeva, L. I., et al.: Eksperimental'naya i Klinicheskaya Farmakologiya, 70, 40 (2007).<br></p>

<p>Applications 5-Benzyl-4H-1,2,4-triazol-3-amine can be used as positive modulators of GABAA1 receptor with potent anticonvulsant activity and low toxicity.<br>References Huang, L., et.al.: Eur. J. Med. Chem., 185, 111824, (2020);<br></p>

<p>Applications Imidazole rings are found in numberous natural compounds such as enzymes, nucleic acid, and alkaloids that play a role in biological processes.<br></p>

<p>Applications 4-Hydroxy-2-piperidinone is a synthetic intermediate in the synthesis of pharmaceutical goods.<br>References Vink, M.K.S., et al.: J. Org. Chem., 67, 7869 (2002);<br></p>

<p>Applications Benzimidazole-4,5,6,7-d4 (CAS# 64531-29-9) is a useful isotopically labeled research compound.<br></p>

<p>Applications A labelled imidazole, a versatile heterocycle used in the preparation of various biologically active compounds such as the amino acid histidine and is present in many antifungal medication. It is also used extensively as a corrosion inhibitor on transition metals such as copper.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Arispe, N. et al.: Biophys. J., 95, 4879 (2008); Troesken, E.R. et al.: Endo. Res., 30, 387 (2004); Otmacic Curkovic, H. et al.: Corr. Sci., 51, 2342 (2009);<br></p>

<p>Applications 3-chloropyridazine hydrochloride (cas# 856847-77-3) is a useful research chemical.<br></p>

<p>Applications Piperonyl Isobutyrate (cas# 5461-08-5) is a useful research chemical.<br></p>

<p>Applications 4-Pyridinecarboxamide 1-Oxide (cas# 38557-82-3) is a compound useful in organic synthesis.<br></p>

<p>Applications N-[1-(pyridin-3-yl)ethyl]hydroxylamine (cas# 887411-44-1) is a useful research chemical.<br></p>

<p>Applications Tetrazolo[1,5-a]pyridin-7-amine is a chemical intermediate for the synthesis of pharmaceutical goods.<br></p>