Heterociclos con nitrógeno (N)

<p>5-Fluorodihydropyrimidine-2,4-dione is a drug that inhibits the activity of certain enzymes. It has been shown to inhibit the activity of dehydrogenase in human serum and liver cells. This drug has also been shown to be successful in treating autoimmune diseases. 5-Fluorodihydropyrimidine-2,4-dione is an oral prodrug which is converted into its active form by esterases in the gastrointestinal tract. The enzyme inhibitors are used to increase the bioavailability of the drug. This conversion process can be monitored using urine samples or blood sampling.</p>

<p>2,4-Dichloro-5-iodopyrimidine is a nucleophilic chemical reagent that can be used to synthesize uracil. It is made by the hydrolysis of 2,4-dichloro-5-iodopyrimidine with sodium hydroxide in water. The reaction yields two isomers which are separated by chromatography. The chemical is used in the synthesis of alkoxides and pyrroles, as well as the synthesis of furans and benzene derivatives. 2,4-Dichloro-5-iodopyrimidine reacts with phosphorus oxychloride to form acetonitrile and oxychloride.</p>

<p>2-Mercapto-5-benzimidazole sulfonic acid sodium salt dihydrate is a molecule that can be used in devices. It has been shown to reversibly change the morphology of a monolayer and to generate asymmetric structures. 2-Mercapto-5-benzimidazole sulfonic acid sodium salt dihydrate can be used to generate fluorescent emulsions, which are systems where the magnetic particles are suspended in an oil droplet and illuminated by light of an appropriate wavelength. The molecules that make up 2-Mercapto-5-benzimidazole sulfonic acid sodium salt dihydrate have been shown to function as acceptors for molecular orbitals, which are wave functions that describe electron distribution around the atomic nucleus. These properties make it a promising candidate for use in microscopy techniques, such as scanning tunneling microscopy (STM) or atomic force microscopy (AFM).</p>

<p>4'-Amino-2,2':6',2''-terpyridine is a fine chemical that can be used as a versatile building block in the synthesis of complex compounds. It has been shown to be useful in the synthesis of various research chemicals and reaction components, including pharmaceuticals and agrochemicals. 4'-Amino-2,2':6',2''-terpyridine is also a reagent for organic synthesis and can be used as a high-quality laboratory chemical.</p>

<p>2,6-Dichloropyridine-1-oxide is a reactive compound that has been synthesized by the reaction of ethyl diazoacetate and trifluoroacetic acid. The synthesis is scalable and can be immobilized in a ruthenium complex. The reactivity of this compound has been studied in kinetic experiments and molecular modeling simulations. 2,6-Dichloropyridine-1-oxide can form an epoxide with ethyl diazoacetate, which is used as the control experiment.</p>

<p>Indole-3-carboxaldehyde is a chemical compound that is used as an antimicrobial agent. The biological properties of this compound are not well studied, but it has been shown to be effective against bacteria and fungi. Indole-3-carboxaldehyde has been shown to inhibit the enzyme activity of sodium carbonate, which is involved in the production of lactic acid in bacteria. This effect may contribute to its antibacterial activity. Indole-3-carboxaldehyde is also a potential anticancer agent because it can bind to toll-like receptor 4 (TLR4). Indole-3-carboxaldehyde reacts with sulfa drugs through a mechanism similar to the reaction between hydrogen peroxide and potassium permanganate. It has been shown that indole-3-carboxaldehyde can be used as a pesticide for plants and as an electrochemical impedance spectroscopy probe for histological analysis.</p>

<p>7-[4-[4-(4-Fluorobenzoyl)Piperidin-1-Yl]Butyl]-1,3-Dimethylpurine-2,6-Dione is a drug that belongs to the group of adenosine receptor antagonists. It has been shown to inhibit phosphodiesterase activity and is used as a pharmaceutical dosage. 7-[4-[4-(4-Fluorobenzoyl)Piperidin-1-Yl]Butyl]-1,3-Dimethylpurine-2,6-Dione has been shown to bind to the 5HT2C receptor in vitro. This drug may have therapeutic potential for obesity and type 2 diabetes mellitus treatment.</p>

<p>1,3,5-Triazine is a nitrogen-containing heterocyclic compound that is used as a precursor for the synthesis of other compounds. It has been shown to inhibit the polymerase chain reaction and to bind to the enzyme DNA polymerase. This binding prevents the formation of an enzyme-substrate complex required for DNA replication. 1,3,5-Triazine also inhibits oxidative injury in experimental models and inhibits cellular physiology by decreasing the production of growth factor-β1. 1,3,5-Triazine has been shown to be a natural compound with inhibitory properties against growth factors and cell proliferation. This chemical also exhibits antioxidant effects by scavenging reactive oxygen species or inhibiting lipid peroxidation.END&gt;</p>

<p>Ethyl indole-3-acetate (EIA) is a compound that inhibits the growth of certain cancer cells. It belongs to the group of acyl halides. EIA inhibits the synthesis of nucleic acids, proteins and other macromolecules by the cancer cells. It has been shown to be effective in reducing the size of tumors in mice with prostate and breast cancer. This compound also inhibits enzymes such as abscisic acid oxidase, which is responsible for converting abscisic acid into reactive oxygen species. EIA has been shown to have hemolytic activity in human lung tissue, but not ovules or human erythrocytes. This may be due to its ability to inhibit hormone production and cause an increase in progesterone levels.</p>

<p>Please enquire for more information about 6-Phenoxy-3-pyridinemethanol including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>3-Amino-4-methylpyridine is a chemical compound that belongs to the group of organic compounds. It is used as an intermediate in the synthesis of podophyllotoxin, a cytotoxic agent that inhibits protein synthesis and cell division. 3-Amino-4-methylpyridine binds to mammalian cells with high affinity and inhibits protein synthesis by inhibiting the enzyme ribosomal protein S6 kinase. This compound also has an inhibitory effect on tofacitinib citrate, which is a drug used for treatment of rheumatoid arthritis. 3-Amino-4-methylpyridine has been shown to be effective against chloride ions in its reaction mechanism, making it suitable for use in organic synthesis.</p>

<p>Used for antibody separation by hydrophobic charge induction chromatography</p>

<p>2-Bromo-3-methylpyridine is a diazido compound with a hydrogen bond. It reacts rapidly with copper chloride to form the coordination complex Cu(diazido)(Cl)2 and an organic product. 2-Bromo-3-methylpyridine can be synthesized from 2,4-dibromopyridine by a cross coupling reaction with copper chloride and calcium carbonate in the presence of sodium potassium bicarbonate. The coordination geometry of the molecule is tetrahedral, with two bromine atoms on opposite sides of the central nitrogen atom and one bromine atom on each side of the pyridine ring. Reaction products are formed as a result of substitution reactions involving halides, such as methyl chloride or ethyl chloride, which act as electrophiles to react with the diazido group. Potential mechanisms include metathesis reactions or cryogenic processes.</p>

<p>3-Methylpiperidin-3-ol is a chemical compound that has been found to be useful as a building block for the synthesis of various complex compounds. This product is used in research and as a reagent. 3-Methylpiperidin-3-ol is also known by the CAS number 473730-88-0.</p>

<p>3,5-Dimethyl-4-nitropyridine 1-oxide is a nitro compound with the chemical formula CHNO. It is an organic compound that has been shown to be carcinogenic in animal studies and has caused cancer in humans. 3,5-Dimethyl-4-nitropyridine 1-oxide can be found in the environment as a result of industrial accidents or environmental pollution. It is found in building materials such as acetonitrile and organic solvents. This compound is not soluble in water, which limits its potential for environmental transport.</p>

<p>Pyridine-2-carboxamidine is an organic compound that is used as a pharmaceutical drug. It is a vasodilator that is used to treat congestive heart failure and eye disorders. Pyridine-2-carboxamidine can also be used to treat muscle diseases and has been shown to reduce insulin resistance in people with type 2 diabetes. This drug is also known for its anti-inflammatory properties, which may be due to the hydroxyl group on the carboxylic acid moiety.</p>

<p>2-Chloro-1-methylpyridinium iodide (2CMPI) is a water-soluble, colorless, and odorless substance that is used as an analytical reagent. 2CMPI reacts with amines and pyridines to form chloromethylpyridine and hydroxymethylpyridine respectively, which can be analyzed by FTIR spectroscopy. The sensitivity of this reaction is affected by the matrix, but can be increased by adding dibutyltin oxide or amide. 2CMPI has been shown to have physiological activities in some animal models of metabolic disorders such as diabetes mellitus.</p>

<p>Ponazuril is a veterinary drug that belongs to the group of chemotherapeutics. It is used in the treatment of endoparasites, such as nematodes and cestodes, which are parasites that live inside the human body. Ponazuril is administered orally or by injection and has been shown to have minimal toxicity in CD-1 mice. Ponazuril binds to DNA polymerase, inhibiting RNA synthesis and protein synthesis. This leads to cell death by apoptosis and necrosis. The drug also inhibits DNA replication in the parasite and blocks parasite growth.</p>

<p>Indole-3-carboxaldehyde is a versatile building block that can be used as an intermediate in the production of complex compounds. It is also a research chemical and reagent for speciality chemicals. Indole-3-carboxaldehyde has been shown to react with other chemicals to form high quality, useful intermediates or reaction components. This compound can also be used as a scaffold for chemical synthesis.</p>

<p>Please enquire for more information about 1-(2-Chloropropanoyl)-4-(2-fluorophenyl)piperazine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-(4-Acetophenoxy)-3-chloro-5-trifluoromethyl pyridine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Methyl 3-amino-6-methylthieno[2,3-b]pyridine-2-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-(5-Methyl-1,3,4-oxadiazol-2-yl)piperidine dihydrochloride is a fine chemical that is a useful building block for research chemicals and speciality chemicals. It is also a versatile intermediate for the synthesis of complex compounds with diverse structures. In addition, 4-(5-methyl-1,3,4-oxadiazol-2-yl)piperidine dihydrochloride can be used as a reagent in the synthesis of pharmaceuticals or other organic compounds. This compound has been assigned CAS No. 1993195-75-7 and its molecular formula is C9H12N2O2.</p>

<p>Applications 3-(Chloromethyl)pyridine Hydrochloride has been used as a reactant for the synthesis of (E)-3-((1H-Indazol-6-yl)methylene)indolin-2-one derivatives as Polo-like kinase 4 (PLK4) inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Laufer, R., et. al.: J. Med. Chem., 56, 6069 (2013)<br></p>

<p>Applications N-Acetyl-3-acetoxy-5-phenylpyrrole (cas# 100750-39-8) is a compound useful in organic synthesis.<br></p>

<p>Applications N-Nitro-1H-imidazol-2-amine is used as a reagent in the synthesis of Imidacloprid-olefin (I274995); a metabolite of Imidacloprid (I274990) which is an active ingredient in certain neuro-active insecticides.<br>References Chauzat, M., et al.: Env. Entomol., 38, 514 (2009); Patial, A., et al.: Env. Ecol., 27, 320 (2009); Fernandez-Bayo, J., et al.: J. Agric., Food Chem., 57, 5435 (2009); Tomizawa, M., et al.: J. Med. Chem., 52, 3735 (2009); Chem. and Eng. News 90: 10 (2012)<br></p>

<p>Applications 1-(N,N-Dimethylsulfamoyl)-1H-imidazole-15N2 is a labelled imidazole (I350202) derivative, used in the preparation of Histamine H3 Receptor Agonists and druglike angiotensin II compounds with affinity for the AT2 receptor.<br>References Wijtmans, M. et al.: J. Med. Chem., 51, 2944 (2008); Georgsson, J. et al.: J. Med. Chem., 50, 1711 (2007)<br></p>

<p>Applications Intermediate in the preparation of labelled Cycloserine (C988802).<br></p>

<p>Applications 4-[4-(Trifluoromethoxy)phenoxy]piperidine is used in the preparation of 3,5-disubstituted isoxazolines as antituberculosis agents.<br>References Sun, D., et. al.: Eur. J. Med. Chem., 44, 460 (2009)<br></p>

<p>Applications Protected N-Benzylpiperazine-d8<br>References Bannwarth, W., et al.: Bioorg. Med. Chem., Lett., 6, 1525 (1996), Greenwald, R., et al.: J. Med. Chem., 43, 475 (2000), Wills, A., et al.: Curr. Opin. Chem. Biol., 7, 346 (2003), Heidler, P., et al.: Bioorg. Med. Chem., 13, 585 (2005),<br></p>

<p>Applications 5,6-Diamino-2,4-dihydroxypyrimidine-13C2, Hydrochloride Salt (cas# 1346605-20-6) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-Hydroxy-1-pyrrolidinecarboxylic Acid 1,1-Dimethylethyl Ester is an intermediate in the synthesis of (E)-6-Amino-2-hexenoic Acid (A609990), used in the preparation of anti-collagenase active agent.<br>References Schmidt, A. M., et al: Org. Biomolec. Chem., 3, 2333 (2005);<br></p>

<p>Applications 5-Bromo-2-(1H-tetrazol-5-yl)pyridine is a reagent in the synthesis and antibacterial activity of oxazolidinones containing pyridine substituted with heteroaromatic ring.<br>References Jo, Y.W., et al.: Bioorg. Med. Chem., 12, 5909 (2004)<br></p>

<p>Applications 6-Ethyl-4-(1-piperazinyl)thieno[2,3-d]pyrimidine Hydrochloride is an intermediate used in the synthesis of 6-Ethyl-4-[4-(1,3,4-thiadiazol-2-yl)-1-piperazinyl]thieno[2,3-d]pyrimidine Hydrochloride (E926745), which is an inhibitor of fusion protein interaction of menin-mixed lineage leukemia (menin-MLL). Menin-MLL inhibitors downregulate the expression of target genes required for MLL fusion protein oncogenic activity and thus effectively reverse MLL fusion protein-mediated leukemic transformation.<br>References Grembecka, J. et al.: Nat. Chem. Biol., 8, 277 (2012);<br></p>

<p>Applications N-(Benzyloxycarbonyl)-4-piperidone<br></p>

<p>Applications 6-[[2-(tert-Butyldimethylsilyloxy)ethyl]methylamino]pyridin-3-ol (cas# 326496-02-0) is a compound useful in organic synthesis.<br></p>

<p>Applications Boronic acid derivatives and their binding affinities with diols.<br>References Yang, W., et al.: Bioorg. Med. Chem. Lett., 12, 2175 (2002), Yang, W., et al.: Med. Res. Rev., 23, 346 (2003),<br></p>

<p>Applications An intermediate in the preparation of CDK inhibitors<br>References Jakobsen, P., et al.: Bioorg. Med. Chem., 8, 2803 (2000), Chu, X., et al.: J. Med. Chem., 49, 6549 (2006),<br></p>

<p>Applications (R)-(-)-4-Benzyl-3-propionyl-2-oxazolidinone-D3 is an intermediate in the synthesis of (S)-3-Hydroxy-2-methylpropanoic Acid-d3 sodium salt (H997291), which is the labelled version of 3-hydroxy-2-methyl-Propanoic acid sodium salt (CAS# 1893416-17-5), a useful building block used in the synthesis of aminotriazine derivatives.<br>References Du, Z.; et al.: WO 2016049211 (2016).<br></p>

<p>Applications Can be used in the preparation of substances for treatment of dermatological conditions and skin protection.<br></p>

<p>Applications 2-chloropyridine-4-carbonyl chloride (cas# 65287-34-5) is a useful research chemical.<br></p>

<p>Applications 2-Aminoimidazole Sulfate (cas# 1450-93-7) is a compound useful in organic synthesis.<br></p>

<p>Applications Reactant used in the preparation of labelled Camptothecin derivatives.<br></p>

<p>Applications (4R)-3-(1-Oxo-3-buten-1-yl)-4-(phenylmethyl)-2-oxazolidinone is an intermediate in the synthesis of emericellamide A, a secondary metabolite of marine cyclic depsipeptide with antimicrobial properties.<br>References Ma, J. Y., et al.: Synlett., 8, 1307 (2009);<br></p>

<p>Applications Hydrochloride salt of N-(β-Chloroethyl)piperidine is used in the inhibition of sickle-cell hemoglobin.<br>References Stubbins, J. et al.: Eur. J. Med. Chem., 14, 219 (1979);<br></p>

<p>Applications 1,​4-​Dimethyl-​3-​phenyl-​1H-​pyrazol-​5-​ol is a reactant used in the preparation of novel strobilurin derivatives as insecticides.<br>References Li, M. et al.: Nat. Prod. Comm., 4, 1215 (2009);<br></p>

<p>Applications (1-Benzyl-1H-imidazol-5-yl)(2,3-dimethylphenyl)methanone is an intermediate in the synthesis of 1-Benzyl-5-(1-(2,3-dimethylphenyl)vinyl)-1H-imidazole (B251400), an impurity of Medetomidine (M203250, HCl); an α2-adrenergic agonist, sedative, and analgesic.<br>References Scheinin, M., et al.: Br. J. Clin. Pharmacol., 24, 443 (1987); Stenberg, D., et al.: J. Vet. Pharmacol. Ther., 10, 319 (1987); Virtanen, R., et al.: Eur. J. Pharmacol., 150, 9 (1988); Cullen, L.K., et al.: Br. Vet. J., 152, 519 (1996)<br></p>

<p>Applications Used in the preparation of piperazine-1-carboxamide derivatives as fatty acid amide hydrolase (FAAH) inhibitors.<br>References Glorius, F., et al.: Org. Biomol. Chem., 3, 4171 (2005),<br></p>

<p>Applications 2,5-Dihydro-3-(hydroxymethyl)-2,2,5,5-tetramethyl-4-(3-pyridinyl)-1H-pyrrol-1-yloxy is an intermediate in the synthesis of highly active spin labelling reagents.<br>References Fawzi, N.L., et al.: J. Biomolec. NMR., 51, 105 (2011);<br></p>

<p>Applications 2-Cyano-3-chloropyridine (cas# 38180-46-0) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-(tert-Butylamino)-4-chloro-6-cyclopropylamino-1,3,5-triazine-d9 (cas# 1189419-70-2) is a compound useful in organic synthesis.<br></p>

<p>Applications 4-Piperidineethanol have been used as an intermediate in the synthetic preparation of cellular-active allosteric inhibitors of FAK<br>References Tomita, N., et al.: Bioorg. Med. Chem., 23, 1779 (2013); Negoro, K., et al.: Bioorg. Med. Chem., 20, 6442 (2012); Giang, H.N., et al.: Macromole. Chem. Phy., 213, 982 (2012);<br></p>

<p>Applications 2-Amino-4-chloro-5-nitropyridine (cas# 24484-96-6) is a compound useful in organic synthesis.<br></p>

<p>Applications Octahydro-6-(phenylmethyl)-1H-Pyrrolo[3,4-b]pyridine-d4 is an isotope labelled intermediate in the synthesis of moxifoxacin (M745000), a fluorinated quinolone antibacterial.<br>References Somisetti, N. et al.: Org. Chem. Indian J., 7, 123 (2011);<br></p>

<p>Applications Reactant in the preparation of CB1 cannabinoid receptor agonists and brain imaging agents.<br>References Deng, H. et al; J. Med. Chem. 48, 6386 (2005)<br></p>

<p>Applications Intermediate in the preparation of GABAA receptor agonists used in antidepressants.<br>References Jones, P., et al.: Bioorg. Med. Chem. Lett., 16, 872 (2006), Baraldi, P., et al.: J. Med. Chem., 50, 374 (2007),<br></p>

<p>Applications Tris(p-tolyl)-1,3,5-triazine is an intermediate in synthesizing p-Cyanobenzoic Acid Trimer (C955200), which is used in the synthetic preparation of Terbium Triazinetribenzoate Formate Metal Organic Framework (MOF).<br>References Han, Y., et al.: J. Mater. Chem. A Mater. Energy Sustain., 3, 24525 (2015);<br></p>

<p>Applications 6-Chloro-4-(2,2,2-trifluoroacetyl)benzo[d]oxazol-2(3H)-one is an intermediate in the synthesis of 6-Chloro-4-[3-cyclopropyl-1-hydroxy-1-(trifluoromethyl)-2-propyn-1-yl]-2(3H)-benzoxazolone (C365790), a impurity of Efavirenz (E425000) which is a nonnucleoside HIV-1 reverse transcriptase inhibitor.<br>References Young, S.D., et al.: Antimicrob. Ag. Chemother., 39, 2602 (1995)<br></p>

<p>Applications ((4S,5S)-4-Isopropyl-2,2,5-trimethyl-1,3-dioxolan-4-yl)methanone 1H-Imidazol-1-yl is an intermediate in the synthesis of (+)-amabiline, an unsaturated pyrrolizidine alkaloid from Cynoglossum amabile.<br>References Senter, T. J., et al.: Org. Lett., 14, 1869 (2012);<br></p>

<p>Applications 2-Chloro-3-iodopyridine (cas# 78607-36-0) is a compound useful in organic synthesis.<br></p>

<p>Applications Intermediate in the preparation of selective cyclooxygenase-2 inhibitors and calcium antagonists<br>References Ashimori, A., et al.: Chem. Pharm. Bull., 38, 2446 (1990), Khanna, I., et al.: J. Med. Chem., 43, 3168 (2000),<br></p>

<p>Applications 2,2,6,6-Tetramethyl-4-piperidinone (cas# 826-36-8) is a compound useful in organic synthesis.<br></p>

<p>Applications (S)-5-Chloro-3-(cyclopropylethynyl)-3-(trifluoromethyl)-1,3-dihydrobenzo[c]isoxazole is a proposed intermediate in the synthesis of (4S)-6-Chloro-4-(3-((4-chloro-2-((S)-4-cyclopropyl-1,1,1-trifluoro-2-hydroxybut-3-yn-2-yl)phenyl)amino)pent-1-yn-1-yl)-4-(trifluoromethyl)-1H-benzo[d][1,3]oxazin-2(4H)-one (Mixture of Diastereomers) (C360045) which is an impurity of Efavirenz (E425000) which is a nonnucleoside HIV-1 reverse transcriptase inhibitor. Antiviral.<br>References Young, S.D., et al.: Antimicrob. Ag. Chemother., 39, 2602 (1995),<br></p>

<p>Applications 4-Chloropyridine-2-carboxamide, is a versatile building block used in synthesis of various chemical compounds.<br></p>

<p>Applications 2-Butyl-5-hydroxy-1H-imidazole (cas# 1026802-97-0) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-Hydroxy-4-(trifluoromethyl)pyrimidine (cas# 104048-92-2) is a compound useful in organic synthesis.<br></p>

<p>Applications Bis(2-Oxo-3-Oxazolidinyl)Phosphinic Chloride (cas# 68641-49-6) is a useful research chemical.<br></p>

<p>Applications 4-[2-(1-Piperidinyl)ethoxy-d4]benzoic Acid, Hydrochloride Salt (cas# 1246815-60-0) is a compound useful in organic synthesis.<br></p>

<p>Applications 5-Amino-3-(1-naphthyl)-4-cyano-1-tert-butylpyrazole (cas# 221243-34-1) is a compound useful in organic synthesis.<br>References Bishop, A.C., et al.: J. Am. Chem. Soc., 121, 627 (1999)<br></p>

<p>Stability Stable at Room Temperature<br>Applications A useful synthetic intermediate.<br></p>

<p>Applications Ethyl 5-Methyl-1-phenyl-1H-pyrazole-4-carboxylate (cas# 89193-16-8) is a compound useful in organic synthesis.<br></p>

<p>Applications Intermediate in the preparation of (+/-)-Iso Myosmine (I821350).<br></p>

<p>Applications α-Methyl-2-piperidinemethanol-13C2 is a labelled analogue of α-Methyl-2-piperidinemethanol (M324830), which can be used in the preparation of substances with herbicidal activity. α-Methyl-2-piperidinemethanol-13C2 is also an intermediate in synthesizing 2-Acetyl-3,4,5,6-tetrahydropyridine-13C2 Hydrochloride (A188502), which is a labelled 2-Acetyl-3,4,5,6-tetrahydropyridine (A188500), the most important bread flavor component.<br>References Buttery, R.G., et al.: J. Agric. Food Chem., 43, 1878 (1995)<br></p>

<p>Applications 2-AMINO-4,6-DICHLOROPYRIMIDINE (cas# 56-05-3) is a useful research chemical.<br></p>

<p>Applications (S)-Benzyl 2-(5-Bromo-1H-indole-3-carbonyl)pyrrolidine-1-carboxylate is an intermediate in the synthesis of ent-Eletriptan (E505005), an enantiomeric impurity of the serotonin 5-HTIB/ID receptor agonist Eletriptan (E505000).<br>References Orita, A., et al.: Green Chem., 3, 13 (2001);<br></p>

<p>Applications 1,1-Dimethylethyl 4-(2-Hydroxyethyl)piperazine-1-carboxylate-d4 is an isotope labelled intermediate in the synthesis of labelled Flupentixol.<br>References Panteleev, J., et al.: Synlett., 26, 953 (2015); Liang, Y.K., et al.: Euro. J. Med. Chem., 84, 505 (2014);<br></p>

<p>Applications Pyridine as novel substrate for regioselective oxygenation with aromatic peroxygenase from Agrocybe aegerita.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Colby, J., et al.: Biochem. J., 165, 395 (1977), Damani, L., et al.: Xenobiotica, 12, 527 (1982), Balzarini, J., et al.: J. Antimicrob. Chemother., 55, 135 (2005),<br></p>

<p>Applications 1-Phenyl-2-pyrrolidone (cas# 4641-57-0) is a compound useful in organic synthesis.<br></p>

<p>Applications 1-(2-Chloroethyl)-2-imidazolidinone (cas# 2387-20-4) is a compound useful in organic synthesis.<br></p>

<p>Applications [4-(4-Fluorophenyl)-6-(1-methylethyl)-2-(methylsulfinyl)-5-pyrimidinyl]-ethyl Ester-d6 (cas# 1189487-47-5) is a compound useful in organic synthesis.<br></p>

<p>Applications 1-(4-Cyanophenyl)piperazine<br></p>

<p>Applications Phenyl 4-Bromo-2-cyclopropylpyridine-1(2H)-carboxylate is an intermediate in synthesizing B-(2-Cyclopropyl-4-pyridinyl)-boronic Acid (C989365), which is used in synthesis of isoindole carboxamides, pyrrolopyridine carboxamides, and similar compounds as inhibitors of phosphodiesterase type 10A for treating neurological and psychiatric disorders.<br>References Geneste, H., et al.: PCT Int. Appl. (2013), WO 2013000994 A1 20130103<br></p>

<p>Applications: N'-Hydroxypyridine-3-carboximidamide<br></p>

<p>Applications 2-[(4-Bromophenyl)methyl]-4,5-dihydro-4,4-dimethyloxazole is an intermediate used in the synthesis of Bilastine-d6 (B385002), which is labelled Bilastine. It is a novel, nonsedating H1-antihistamine developed for symptomatic treatment of allergic rhinitis and chronic idiopathic urticaria.<br>References Van Cauwenberge, P., et al.: Clin. Exp. Allergy, 30, 891 (2000), Bauchau, V., et al.: Eur. Respir. J., 24, 758 (2004), Lehman, J., et al.: Drugs, 66, 2309 (2006),<br></p>

<p>Applications 3-Formyl-2,5-dihydro-2,2,5,5-tetramethyl-4-(3-pyridinyl)-1H-pyrrol-1-yloxy is an intermediate in the synthesis of highly active spin labelling reagents.<br>References Fawzi, N.L., et al.: J. Biomolec. NMR., 51, 105 (2011);<br></p>

<p>Applications Pyridine hydrobromide (cas# 18820-82-1) is a useful research chemical.<br></p>