Heterociclos con nitrógeno (N)

<p>Applications 4-Hydroxypiperidine-3,3,4,5,5-d5-N-t-BOC (CAS# 1523606-18-9) is a useful isotopically labeled research compound.<br></p>

<p>Applications 1-(N,N-Dimethylsulfamoyl)-1H-imidazole is an Imidazole (I350200) derivative, used in the preparation of Histamine H3 Receptor Agonists and druglike angiotensin II compounds with affinity for the AT2 receptor.<br>References Wijtmans, M. et al.: J. Med. Chem., 51, 2944 (2008); Georgsson, J. et al.: J. Med. Chem., 50, 1711 (2007)<br></p>

<p>Applications 2,2'-Bipyridine-4,4'-dicarboxamide<br></p>

<p>Applications 4,6-Diamino-2-chloro-5-pyrimidinecarbonitrile is an intermediate in the synthesis of 2,4,6-Triamino-5-pyrimidinecarbonitrile is a photodegradation product of two isostructural pesticides in aqueous solution: Cyromazine (C989300) and Dicyclanil.<br>References Kimbrough, R., et al.: Environ. Sci. Technol., 30, 908 (1996), Root, D., et al.: Pesticide Sci., 48, 25 (1996), Yokley, R., et al.: J. Agric. Food Chem., 48, 3352 (2000),<br></p>

<p>Applications 5-Amino-3,4-dimethylisoxazole (cas# 19947-75-2) is a compound useful in organic synthesis.<br>References Tellew, J., et al.: Bioorg. Med. Chem. Lett., 13, 1093 (2003),<br></p>

<p>Applications Pyrimidin-4-ylboronic Acid is an intermediate used to prepare aldosterone synthase inhibiting pyrimidinylnaphthalenes via Suzuki cross-coupling reactions. It is also used in the synthesis of [7-(2,6-dichlorophenyl)-5-methylbenzo [1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-ylethoxy)phenyl]amine as a potent, orally active Src kinase inhibitor with antitumor activity.<br>References Voets, M., et al.; J. Med. Chem., 48, 6632 (2005); Noronha, G., et al.: Bioorg. Med. Chem. Lett., 17, 602 (2007)<br></p>

<p>Applications 4-Hydroxy-2,2,6,6-tetramethylpiperidine-d17-1-oxyl (CAS# 100326-46-3) is a useful isotopically labeled research compound.<br></p>

<p>Applications A pyrolopyrimidine derivative used in the preparation of the antibiotic tubercidin (7-deazadenosine).<br>References Ektova, L.V. et al.: Bioorg. Khim., 4, 1250 (1978);<br></p>

<p>Applications 6-NITROPIPERONYL ALCOHOL (cas# 15341-08-9) is a useful research chemical.<br></p>

<p>Applications Tris(4-pyridyl)-s-triazine is used in the preparation of metal-metallite coordination polymers as well as porphyrin prisms.<br>References Youm, K. et al.: Chem. Comm., 29, 3375 (2008); Li, M. et al.: CrystEngComm., 15, 1225 (2013);<br></p>

<p>Applications 6-METHYL-5-PROPYL-4(1H)-PYRIMIDINONE (cas# 103980-68-3) is a useful research chemical.<br></p>

<p>Applications Used in the preparation of indoline derivatives as PERK inhibitors.<br></p>

<p>Applications Diethyl(pyridin-​4-​yl)​borane is a powerful reducing agent used in the synthesisof non-basic compounds as factor Xa inhibitors. Diethyl(pyridin-​4-​yl)​borane is used for the synthesis of 4-aryl- and 4-heteroarylpyridines by the palladium-catalyzed cross-coupling reaction.<br>References Komoriya, S. et al.: Bioorg. Med. Chem. 13, 3927 (2005); Ishikura, Minoru., et al.: Chem. Pharm. Bull., 33, 4755(1985)<br></p>

<p>Applications 3-Amino-1,4-dimethylpyrazole is used in the preparation of peptides as cysteine protease inhibitors.<br></p>

<p>Applications 2-Hydroxyethylbenzimidazolidinone-2 (cas# 63388-01-2) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-Pyrazinecarboxylic Acid 4-Oxide (cas# 874-54-4) is a compound useful in organic synthesis.<br>References Ambrogi, V., et al.: Eur. J. Med. Chem., 15, 157 (1980),<br></p>

<p>Applications imidazo[1,2-a]pyridin-7-amine hydrobromide (cas# 1630906-80-7) is a useful research chemical.<br></p>

<p>Applications 2-Pinacolateborylpyrrole is a useful reagent for organic reactions.<br>References Pati, N.N., et al.: Eur. J. Org. Chem., 2017, 741-45 (2017); Kise, K., et al.: Chem. Lett., 46, 1319-22 (2017);<br></p>

<p>Applications 5,6-Diamino-2,4-dihydroxypyrimidine, Hydrochloride Salt (cas# 53608-89-2) is a compound useful in organic synthesis.<br></p>

<p>Applications 2,3-Dichloro-5-(trifluoromethyl)pyridine is a reactant that has been used in the synthesis of a 17β-HSD1 inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zhou, Q., et. al.: Tetrahedron, 69, 10996 (2013)<br></p>

<p>Applications α,α,1,6-Tetramethyl-3-piperidinemethanol, has shown to be able to facilitate new modes of reactivity via constrictive binding in a supramol.-assembly-catalyzed aza-Prins cyclization.<br>References Kaphan, D. M., et al.: Journal of the American Chemical Society, Vol. 137, P: 9202-9205 (2015);<br></p>

<p>Applications (2R,4S)-4-Aminopyrrolidine-2-carboxylic acid dihydrochloride (cas# 263407-17-6) is a useful research chemical.<br></p>

<p>Applications (7H-Pyrazolo[3,4-b]pyridin-5-yl)methanamine Hydrochloride is a useful research chemical.<br></p>

<p>Applications 3,4-Dihydro-2(1H)-pyridinone is used as a reactant for the regio- and stereoselective preparation of lactam-fused quinoline derivatives via Povarov-type multicomponent reaction of aldehydes, anilines, and unsaturated lactams followed by oxidation or fragmentation reactions.<br>References Vicente-Garcia, E., et al.: Org. Lett., 12, 860 (2010)<br></p>

<p>Applications 5-Cyclohexyl-2-piperidinecarboxylic Acid is a compound useful in organic synthesis.<br></p>

<p>Applications Oxazolidine-4-carboxylic acid hydrochloride (cas# 162285-30-5) is a useful research chemical.<br></p>

<p>Applications 4-Benzyloxazolidine-2,5-dione (cas# 583-47-1) is a useful research chemical.<br></p>

<p>Applications N-[[(2S)-1-Ethyl-2-pyrrolidinyl]methyl]carbamic Acid 1,1-Dimethylethyl Ester is an building block in the synthesis of Amisulpride (A633250) related compound.<br></p>

<p>Applications 1-(Formamidomethyl)-1H-benzotriazole is a useful reagent for the synthesis 1-​isocyanomethyl azoles and related compounds.<br>References Saikachi, H., et al.: Chem. Pharm. Bull., 31, 723 (1983)<br></p>

<p>Applications Piperonyl Methoxyethyl Ether-d3 is the isotope labelled analog of Piperonyl Methoxyethyl Ether (P490475); a selective inhibitor of the cytochrome P450-dependent monooxygenase from the housefly.<br>References Motoyama, N., et al.: Rev. Pestic. Toxicol., 1, 173 (1991)<br></p>

<p>Applications An intermediate of Rosuvastatin (R700500).<br></p>

<p>Applications Diethyl Pyridine-2,3-dicarboxylate is a useful reagent in preparation of herbicides.<br>References Doehner, R.: Eur. Pat. Appl. (1988), EP 254951 A2 19880203.<br></p>

<p>Applications 3-Bromopicolinic Acid Sodium Salt (cas# 1189933-55-8) is a compound useful in organic synthesis.<br>References See mercaptopicolinic acid file<br></p>

<p>Applications 2-Oxo-2-(1-phenyl-1H-pyrazol-4-yl)acetic Acid is a derivative of N-Phenylpyrazole, a reactant in the synthesis of candesartan cilexetil(C175580), an ester prodrug; hydrolized in vivo to the active carboxylic acid. Used in treatment of congestive heart failure. Antihypertensive.<br>References Seki, M. et. al: ACS Catalysis, 4, 4047 (2014); Shibouta, Y., et al.: J. Pharmacol. Exp. Ther., 266, 114 (1993; Ogihara, T., et al.: Clin. Ther., 16, 74 (1994)<br></p>

<p>Applications Ethyl 2,5-Dibromo-1,3-oxazole-4-carboxylate is useful for the synthesis of substituted oxazoles.<br>References Hodgetts, K. J., et al.: Org. Lett., 4, 2905-2907 (2002)<br></p>

<p>Applications Isotope labelled 1-Ethyl-5-hydroxy-2-pyrrolidinone (E919175), an important organic solvent used in varnishing. Industrial solvent.<br>References Koch, H. et al. Arch. Toxicol., 88, 893 (2014); Koslitz, S. et al.: Toxicol. Lett., 231, 142 (2014);<br></p>

<p>Applications 2-Amino-3-hydroxypyridine (cas# 16867-03-1) is a compound useful in organic synthesis.<br></p>

<p>Applications Picolinic acid (P437220) derivative used in the synthesis of oxazine derivatives that act as BACE inhibitors for treatment of diabetes and neurological disorders.<br></p>

<p>Applications 5-Bromohexahydro-2,6-dioxo-4-pyrimidinecarboxylic Acid-15N2 is an intermediate used in the synthesis of Orotic Acid-15N2 Monohydrate (O691504), which is a labeled analogue of Orotic Acid Monohydrate (O691500) that is used in the preparation of therapeutic agents for chronic obstructive pulmonary disease (COPD) treatment. Also, it is the labeled form of 5-Bromohexahydro-2,6-dioxo-4-pyrimidinecarboxylic Acid (B699363), an intermediate in synthesizing Orotic Acid Monohydrate (O691500), which is used in the preparation of therapeutic agents for chronic obstructive pulmonary disease (COPD) treatment.<br></p>

<p>Applications tert-Butyl-7-[4-(4-fluorophenyl)-6-isopropyl-2-aminopyrimidin-5-yl]-(3R,5S)-isopropylidene-(E)-6-heptenoate (cas# 1448436-04-1) is a compound useful in organic synthesis.<br></p>

<p>Applications 1-Ethyl-2-piperazinone is used in the synthesis of piperidine and piperazine derivatives as cognition enhancers.<br>References Bioorg, Med. Chem., 16, 1431 (2008);<br></p>

<p>Applications 2-Chloro-5-(phenylsulfonyl)pyridine is a starting material and useful building block of various pharmaceuticals.<br></p>

<p>Impurity Irbesartan Bromo N2-Trityl Impurity<br>Stability Moisture Sensitive<br>Applications An intermediate in the synthesis of Losartan and Valsartan.<br></p>

<p>Applications 3H,4H,5H,6H,7H-[1,2,3]triazolo[4,5-c]pyridine (cas# 706757-05-3) is a useful research chemical.<br></p>

<p>Applications Methyl 3-(1-Tritylimidazol-4-yl) Propionate (cas# 102676-60-8) is a compound useful in organic synthesis.<br></p>

<p>Applications 1-[2-(1,1-Dimethylethyl)phenyl]pyrrolidine, is a building block used in the synthesis of chemical compounds having therapeutic activity.<br></p>

<p>Applications Isotope labelled B-[1-(Tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl]boronic Acid is used in the preparation of ALK receptor mediators.<br></p>

<p>Applications 4'-(Imidazol-1-yl)acetophenone (cas# 10041-06-2) is a useful research chemical.<br></p>

<p>Applications 4-Pyridineacetic Acid Hydrochloride is used in the preparation of a highly tumor-selective organometallic ruthenium(II)-Arene complex.<br>References Clavel, C.M., et. al.: J. Med. Chem., 57, 3546 (2014)<br></p>

<p>Applications 2,3,5,6-Tetramethylpyrazolo[1,2-a]pyrazole-1,7-dione (cas# 68654-22-8) is a compound useful in organic synthesis.<br></p>

<p>Applications 1-(4-Chlorophenyl)-3-[(2-nitrophenyl)methoxy]pyrazole is an intermediate for the synthesis of Pyraclostrobin-d6 (P840402). Isotope labelled Pyraclostrobin is a fungicide for use in seed grass and food crops.<br>References Gyldenkaerne, S., et al.: Pestic Sci., 55, 1210 (1999), Pennington, D., et al.: Environ. Sci. Technol., 39, 1119 (2005), Wang, S., et al.: Food Control., 18, 731 (2007),<br></p>

<p>Applications 3-​Methoxy-​4-​methyl-​1H-​1,​2,​4-​triazol-​5(4H)​-​one Hydrate, is a Triazole (T767410) derivative that was used in microwave synthesis of 1,2,4-triazolone derivatives possessing antifungal activity. 3-​Methoxy-​4-​methyl-​1H-​1,​2,​4-​triazol-​5(4H)​-​one is also a key intermediate for sulfonylurea herbicides, such as flucarbazone.<br>References Su, J., Shang, Z.: Nongyao, 49, 563 (2010); Sun, N., et al.: BioMed Res. Int., 1 (2015);<br></p>

<p>Stability Hygroscopic<br>Applications PIPERIDINE-2,6-DICARBOXYLIC ACID (cas# 499-82-1) is a useful research chemical.<br></p>

<p>Applications Ethyl 5-(thiophen-2-yl)isoxazole-3-carboxylate is a useful reagent for organic synthesis.<br></p>

<p>Applications 2-Chloro-3-nitropyridine (cas# 5470-18-8) is a useful research chemical.<br></p>

<p>Applications OXAZOLE-5-CARBOXYLIC ACID HYDRAZIDE (cas# 885274-30-6) is a useful research chemical.<br></p>