Compuestos heterocíclicos

Applications oxazole-4-carbohydrazide (cas# 885274-12-4) is a useful research chemical.

Applications Methyl Hyroxy-2-(tetrahydro-2H-pyran-4-yl)acetate is a useful research intermediate for organic synthesis.

Applications Sulfinpyrazone sulfone can be used to help with atherosclerosis in various animals. This compound can be used in High Pressure-Liquid Chromatography.
References Lentjes,E.G., et.al., Pharm.Weekbl.7,252-259,(1986); Clopath, P.et.al., Cardiovasc.Actions Sulfinpyrazone: Basic Clin. Red., Proc.Int.Symp., 121-137,(1980);

Applications 2-carboxythiophene-3-boronic acid (cas# 5503-74-2) is a useful research chemical.

Impurity Abacavir - In House Impurity
Applications rac 2-Azabicyclo[2.2.1]hept-5-en-3-one (Abacavir - In House Impurity) is a useful reagent in the synthesis of carbocyclic sugar amines, carbanucleosides, and carbocyclic dinucleotide analogues (1). rac 2-Azabicyclo[2.2.1]hept-5-en-3-one is also an intermediate of Abacavir (A104990), a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.
References (1) Slama, J.T., et al.: Biochemistry, 27, 183 (1988) (2) Jackson, A., et al.: Antivir Ther. 17, 19 (2012) (3) Yuen, G. J., et al.: Clin Pharmacokinet. 47, 351 (2008)

Applications N-Nitroso-3-hydroxy Pyrrolidone is an N-Nitroso impurity, Nitrosamines are known carcinogens in a wide range of animal species.
References Ohshima, H., et al.: Cancer Lett., 26, 153, (1985)

Applications 6-Ethoxy-3-hydroxypyrazine-2-carboxamide is a useful intermediate for organic synthesis.

Stability Hygroscopic
Applications 3-(1-Nitroethyl)-2-benzofuran-1(3H)-one (cas# 79017-08-6) is a useful research chemical.

Applications 4,4-dimethyldihydrofuran-2,3-dione (cas# 13031-04-4) is a useful research chemical.

Applications N,N'-Dimethylpiperazine is used in preparation of two-component raw material of high-strength Polyurethane Insulation pad for cold storage.Also, used in preparation of Methylaliphatic Amines from aliphatic Amines and Methanol.
References Dou, Z., et al.: Faming Zhuanli Shenqing, (2020); Li, F., et al.: Faming Zhuanli Shenqing, (2020);

Applications 2-Aminothiazole-4-carboxamide is a useful intermediate for organic synthesis and other chemical processes.
References Sanghvi, Y. S., et al.: J. Heterocycl. Chem., 25, 623 (1988); Wu, J., et al.: Bioorg. Med. Chem. Lett., 17, 4664 (2007)

Applications Phenazine (cas# 92-82-0) is a compound useful in organic synthesis.

Applications 2-(Thiophen-2-yl)acetamide is used in preparation of [18F]Maleimide-based Glycogen synthase kinase-3β ligands for positron emission tomography imaging.
References Lee, Katarzyna N., et al.: PCT Int. Appl., (2018);

Applications Tetrahydrofuran-2,5-dicarboxylic acid (CAS# 6338-43-8) is a useful research chemical compound.

Applications pyridazin-4-ylmethanol (cas# 50901-43-4) is a useful research chemical.

Applications N-2-Propyn-1-yl 1-Piperazinesulfonamide Hydrochloride is a chemical reagent used for synthesis of pharmaceuticals. Similar to 1-Prop-2-ynylpiperazine (P839243) a chemical reagent.
References Pajk, S. et al.: J. Enz. Inhib. Med. Chem., 35, 498 (2020);