Building Blocks

Versatile small molecule scaffold

<p>4-Bromo-N-(sulfanylidenemethylidene)benzamide is a nitro compound that has been shown to be carcinogenic in rats. It was synthesized by reaction of 4-bromobenzoyl chloride with dimethylamine and thiourea. The nitro group on the benzene ring is reduced to the amine group, while the nitro group on the amino group is oxidized to the mixed anhydride, which undergoes acid hydrolysis to form picric acid. This residue was then neutralized with sodium hydroxide and converted into a chloride salt. The chemical structure of this compound resembles that of heterocyclic amines, which are known carcinogens.</p>

<p>2-[(2-Methoxy-4-nitrophenyl)amino]ethan-1-ol is a scientific chemical that is used in the production of care products. It is an allergen, as it has been shown to cause allergic reactions in population studies. Care products containing 2-[(2-Methoxy-4-nitrophenyl)amino]ethan-1-ol can cause sensitization, even if they are not directly applied to the skin. This chemical is tested for use in human subjects and for sensitization tests in animals. 2-[(2-Methoxy-4-nitrophenyl)amino]ethan-1-ol can be found in the environment due to its widespread use and accidental spills.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Ceftriaxone is an antibacterial agent that has a broad spectrum of activity against Gram-positive and Gram-negative bacteria. Ceftriaxone binds to the beta-lactam ring of the bacterial cell wall, inhibiting the synthesis of peptidoglycan, which is necessary for the bacterial cell wall to maintain its shape. Ceftriaxone can be used to treat a number of bacterial infections and is active against both aerobic and anaerobic bacteria. Ceftriaxone has been shown effective against drug-resistant strains, such as staphylococcus aureus and escherichia coli. It has also been shown to be active against strains resistant to other antibiotics such as erythromycin, penicillin, tetracycline, chloramphenicol, and clindamycin. Ceftriaxone's molecular structure was determined by X-ray crystallography.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>5-[(2-Methylpropyl)amino]-1,3,4-thiadiazole-2-thiol is a modification of the oligosaccharide. It is a monosaccharide with a methyl group at the C5 position and a fluorine atom at the C4 position. 5-[(2-Methylpropyl)amino]-1,3,4-thiadiazole-2-thiol is synthesized by reacting 2-(methylpropyl)amine with thiadiazole dithiole. This compound has CAS No. 66180-54-9 and can be used as an intermediate in the synthesis of complex carbohydrates. The carbohydrate structure of 5-[(2-Methylpropyl)amino]-1,3,4-thiadiazole-2-thiol consists of a glycosidic linkage between two saccharides: a hexose and an acetal</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>3-Benzylpyrrolidine-2,5-dione is a potent and selective serine protease inhibitor. It binds to the active site of the enzyme, blocking the formation of an acyl enzyme intermediate that is required for biological activity. 3-Benzylpyrrolidine-2,5-dione is effective at inhibiting a wide range of serine proteases, including those from bacteria and viruses. This drug has been shown to be chemically stable in solution and does not react with other molecules in solution, which may be due to its carbonyl group. 3-Benzylpyrrolidine-2,5-dione also irreversibly inhibits serine proteases by covalent modification of key amino acid residues on the enzyme's active site.</p>

<p>Versatile small molecule scaffold</p>

<p>Diethyl bromomethylphosphonate is a chemical compound with fatty acid properties. It is used as an inhibitor in pharmaceutical preparations and has been shown to be bactericidal to animals. Diethyl bromomethylphosphonate also inhibits the enzyme fatty acid synthase, which catalyzes the formation of fatty acids from acetyl-CoA and malonyl-CoA. This inhibitor is used in the treatment of congestive heart failure and insulin resistance. Diethyl bromomethylphosphonate is a functional group that can undergo hydrolysis by hydrochloric acid, leading to the release of diethyl methylphosphonite. Diethyl bromomethylphosphonate is a chemical compound that can react with organic solvents such as water or alcohols for reactions.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>1-Methyl-3,4-dinitro-1H-pyrazole is a chemical compound that is not naturally occurring. It has been synthesized by the reaction of 1,2-diaminoethane with nitric acid and dinitrobenzene. The synthesis of this compound was first reported in 1966 by an Australian research team. The magnetic resonance spectrum of this compound showed a monoclinic crystal structure with a molecular weight of 166.19 g/mol. The molecular formula for this compound is C6H5N3O2 and it has an empirical formula of C6H5N3O2I. The yield for this reaction was found to be 85%.</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>3-Amino-N-methyl-4-(methylamino)benzenesulfonamide is a synthetic compound that is used in the synthesis of oligosaccharides and polysaccharides. It is also used as a reagent for the methylation of saccharide, carbonyls and amines. 3-Amino-N-methyl-4-(methylamino)benzenesulfonamide has been shown to be useful in click chemistry reactions.</p>

<p>3-Amino-4-(methylamino)benzoic acid is a modified amino acid that is used in the synthesis of proteins. It has been shown to inhibit the growth of retinoblastoma cells and to bind to specific sites in cellular protein, thereby inhibiting protein synthesis. 3-Amino-4-(methylamino)benzoic acid has also been shown to be effective as a linker in chemical ligation reactions, which can be used for the synthesis of peptides and proteins. This compound has not been found to have any biochemical or chemical modifications.</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)pent-4-ynoic acid is a synthetic amino acid that has been used to study bacterial resistance. The molecule was synthesized by the reaction of 9H-fluorene with pentanenitrile. This organic compound is an isomer of 2,3,4,5,6-pentafluoroheptanoic acid and can be analyzed by FTIR spectroscopy. It has been used to calibrate the mass spectrometer and identify the isomerism in amino acids. The molecule also has diagnostic potential as it can be used to detect the presence of carbohydrates in a sample. 2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)pent-4-ynoic acid is also a protonated molecule that reacts with matrix ions

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>2-Chloro-3-iodopyrazine is a reactive compound that can be used to synthesize diazines. This compound reacts readily with lithium metal in the presence of magnesium to form the corresponding Grignard reagent. The Grignard reagent then reacts with carbon monoxide to produce the desired diazine. 2-Chloro-3-iodopyrazine can also be converted to a functionalized heterocycle through sonication, which produces cinnoline and halogen as products.<br>2-Chloro-3-iodopyrazine is not soluble in water but will react with alcohols such as ethanol and methanol, producing chloroethanol and chloromethyl ether, respectively.</p>

{4-[(2-Aminophenyl)sulfanyl]butyl}phosphonic acid is a polymerase chain reaction (PCR) reagent that is used to detect the presence of nucleic acids in solution. It is a phosphonic acid derivative that has been shown to be effective against both human and animal pathogens, such as HIV, hepatitis B and C, influenza A and B, RSV, and vaccinia virus. This compound can also be used as an inhibitor of DNA polymerases in the presence of radiation or natural compounds.

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

2-Methyl-5-(trifluoromethyl)-1H-pyrrole-3-carboxylic acid is a photosynthetic compound that is also an acid complex. It has been shown to inhibit the synthesis of chlorophyll a., which is necessary for photosynthesis in plants. This compound also has the ability to chelate ligands and bind to proton, which can affect electron transfer. 2-Methyl-5-(trifluoromethyl)-1H-pyrrole-3-carboxylic acid can be found in redox potentials. The redox potential is the measure of oxidation or reduction with respect to the equilibrium between oxidized and reduced forms of a species at a particular temperature. It has also been shown to have an antiinflammatory effect on bowel disease, such as inflammatory bowel disease.

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>