Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

N-Phenyl-2-(dicyclohexylphosphino)pyrrole is a palladium catalyst used in organic synthesis. It is soluble in anhydrous solvents and is selective for reactions that require chloride as the source of the leaving group, such as cyanoacetic acid and phenylbutyrate. N-Phenyl-2-(dicyclohexylphosphino)pyrrole can be prepared by reacting bromobenzene with dimethyl acetylenedicarboxylate followed by treatment with ammonium chloride and heating at reflux. The reaction product can be isolated by precipitation from a mixture of ethanol and water.

<p>5-(4-Fluorophenoxy)pyridin-2-amine is a chemical compound which is used in the preparation of Chinese medicines. It has been shown to interact with calcium carbonate, section and calibration, as well as radiation and particle. 5-(4-Fluorophenoxy)pyridin-2-amine also has significant interactions with ethanolic extracts and servicing. This compound is found in dynamometers and optical systems, and can be used for positioning purposes. 5-(4-Fluorophenoxy)pyridin-2-amine can be used to dry weight and calibrate an optical system. It also has optically detectable properties that are useful for laser ablation preparations.</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

2-Bromo-4-phenylbutanenitrile is a quinoline derivative that is used in the synthesis of nitriles, thiophenes, and pyridines. This compound can be obtained by cross-coupling reactions with organometallic reagents such as iodides and pyridines. The use of 2-bromo-4-phenylbutanenitrile in synthesis allows for enantioselective syntheses. This compound is also a nucleophile, which can be used to introduce a carbon atom into organic compounds. 2-Bromo-4-phenylbutanenitrile can be reduced with lithium aluminum hydride or sodium borohydride to form an alcohol or an amine respectively.

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>N-Methoxy-N-methylcyclopropanecarboxamide is a selective inhibitor of the enzyme azaindole synthase. This drug was shown to be efficacious in vivo in rats with an azaindole-resistant strain of neutrophil leukemia. It also showed efficacy in vitro against human neutrophils and erythrocytes, as well as human blood cells. Azaindole synthase is an enzyme that catalyzes the synthesis of azaindoles from indole and acetaldehyde. This compound has been identified as a lead optimization candidate for treatment of certain cancers, such as leukemia and lymphoma.</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

3-Methoxynaphthalene-1-carboxylic acid is a biotransformed product of guanine and aziridine, which is involved in the formation of amide. 3-Methoxynaphthalene-1-carboxylic acid has been shown to inhibit tumor growth in vivo. It also has an antitumor effect on cultured cells and impurities that are present in the drug can be removed by preparative high performance liquid chromatography (HPLC). 3-Methoxynaphthalene-1-carboxylic acid inhibits bacterial growth by binding to DNA gyrase and topoisomerase IV, which are enzymes that maintain the integrity of bacterial DNA. 3-Methoxynaphthalene-1-carboxylic acid has not been tested as a potential antihypertensive agent. The cytotoxic activity of this compound is mainly due to its ability to interfere with DNA replication and

<p>5-Propoxy-1H-indole is a small molecule that inhibits protein synthesis at the level of translation. It binds to mammalian ribosomes and prevents the amino acid transfer, thereby inhibiting protein synthesis. 5-Propoxy-1H-indole has been shown to inhibit the production of proteins in cells in culture, and also has a strong effect on neuronal function in vivo. This drug has been shown to have clinical relevance for Parkinson's disease, as it may be used to treat symptoms such as tremors, rigidity, and bradykinesia.</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

3-[(2-Methoxyphenyl)sulfamoyl]benzoic acid is a synthetic small molecule that inhibits the activity of peptidases and is used as an activator for protein interactions. It has been shown to inhibit the activity of trypsin, chymotrypsin, and elastase. 3-[(2-Methoxyphenyl)sulfamoyl]benzoic acid also binds to receptors and ion channels in cells, and can be used as a research tool or as a reagent in antibody production. This chemical has high purity with less than 1% water content.

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

(2S)-2-Amino-4-methyl-N-phenylpentanamide is a peptide that is used as an inhibitor of plant diseases. It binds to the active site of the enzyme alkoxy radical, which prevents the formation of reactive oxygen species and protects plants from oxidative damage. The residue that this compound leaves behind is also useful for determining whether or not a protein has been synthesized with an amino acid substitution. (2S)-2-Amino-4-methyl-N-phenylpentanamide can be used to determine whether or not two enantiomers have reacted with each other to form a diastereomer in a kinetic reaction.

Versatile small molecule scaffold

<p>Methyl 2-amino-6-iodobenzoate is a compound that belongs to the group of nitro compounds. It is problematic and toxic to humans.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

1-(3-Phenylprop-2-enoyl)piperidine-4-carboxylic acid is an antibiotic that belongs to the group of natural products. It has been shown to be active against a wide range of bacteria, fungi, viruses, and parasites. 1-(3-Phenylprop-2-enoyl)piperidine-4-carboxylic acid is used in chemotherapy and as a medicine for bacterial infections. This antibiotic also shows antiviral and antiparasitic effects. It binds to the ribosomes of the microbe, preventing protein synthesis and causing cell death.

<p>Versatile small molecule scaffold</p>

<p>1-(Sulfamoylamino)propane is a synthetic sulfonamide with a chemical ionization mass spectrum. It has been shown to inhibit drug-metabolizing enzymes such as cytochrome P450, which may lead to increased levels of the active form of the drug. This compound has been studied for its potential use in Alzheimer's disease and cardiovascular diseases. 1-(Sulfamoylamino)propane also inhibits viral replication and β-amyloid production, and it is an anti-infective agent.</p>

<p>(Ethylsulfamoyl)amine is a drug that can be used as a cancer therapy. It has been shown to inhibit the growth of cancer cells by targeting mitochondrial functions and protein synthesis. The drug also has anti-inflammatory properties and can be used to treat depression, but is not effective in treating bacterial infections. (Ethylsulfamoyl)amine is an amide with sulfamate and sulfamic acid functional groups. It has been shown to have antimicrobial activity against certain bacteria such as Mycobacterium tuberculosis, Escherichia coli, Staphylococcus aureus, Streptococcus pyogenes, Pseudomonas aeruginosa, Klebsiella pneumoniae, and Proteus mirabilis. (Ethylsulfamoyl)amine is also an aliphatic hydrocarbon with heterocyclic properties that can be used as a hypoxic tumor-targeting particle for radiation therapy.</p>