Building Blocks

Versatile small molecule scaffold

Versatile small molecule scaffold

Ethyl 3-formyl-1H-pyrrole-2-carboxylate is a formyl compound with the molecular formula C8H8O3. It is a colorless liquid that has a strong odor. The compound can be obtained by the reaction of ethyl acetoacetate and pyrrole in the presence of aluminum chloride. The compound has been studied for its nuclear magnetic resonance (NMR) properties. It has two conformers, which are distinguished by their different chemical shifts, and this difference can be used to study coupling between the carbonyl group and other groups in the molecule.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

2-Methoxy-benzenesulfonic acid is a synthetic chemical compound that is used in the production of polymers and other ester compounds. It can be produced by reacting benzenesulfonyl chloride with methanol in the presence of a strong acid catalyst. 2-Methoxy-benzenesulfonic acid reacts with radiation to produce reactive oxygen species that are capable of damaging cellular structures. The molecule contains an intramolecular hydrogen bond, which stabilizes the structure and helps to form hydrogen bonds with other molecules. 2-Methoxy-benzenesulfonic acid also has a hydroxyl group, which allows it to function as an acidic compound that can react with water and cause inflammation. This functional group also makes it soluble in water, allowing it to penetrate tissue structures.

N-Boc-4-piperidineacetaldehyde is a chiral, stable, and readily available aldehyde. It has been used in the synthesis of various biologically active molecules including imidazolidinones, which are important for their use as catalysts in organic chemistry. The synthesis of this molecule by the condensation of 4-piperidineacetic acid with acetaldehyde followed by reduction with sodium borohydride is an example of this type of reaction. N-Boc-4-piperidineacetaldehyde can be used to synthesize imines and linkers that are covalently bonded to the protein backbone. This molecule also has conformational stability and is not susceptible to oxidation or radiation damage.

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Laudanosine is a gamma-aminobutyric acid (GABA) analog that is metabolized by the liver to form laudanosine. Laudanosine has been shown to be a competitive antagonist of benzodiazepine binding sites, including those of atracurium, mivacurium chloride, and diazepam. Laudanosine has also been shown to inhibit cyclic nucleotide phosphodiesterases in vitro, with clinical relevance for its use as an anti-epileptic drug.

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Please enquire for more information about 4-Chloro-N-[2-(1,2-dihydro-2-oxo-4-quinolinyl)ethyl]benzamide including the price, delivery time and more detailed product information at the technical inquiry form on this page

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2-Amino-4-bromopyridine is a potent, selective antagonist of the nicotinic acetylcholine receptor (nAChR) that has been shown to inhibit the proliferation of cancer cells in vitro. 2-Amino-4-bromopyridine binds to the nAChR and stabilizes it by binding to an allosteric site on the receptor. 2-Amino-4-bromopyridine is synthesized from 4,5-dibromobenzene and 2,6-diaminopyridine in two steps with a yield of 47%. The synthesis of 2-amino-4-bromopyridine proceeds via reaction mechanism involving electrophilic substitution at the bromine atom followed by nucleophilic addition at the nitrogen atom.

2-Acetylbenzoic acid is a functional molecule that contains an acetyl group. It can form hydrogen bonds with other molecules and has been shown to induce apoptosis in cells. The reaction products of 2-acetylbenzoic acid are malonic acid, acetylsalicylic acid, and 2-benzoylbenzoic acid. These three compounds are made by the addition of hydrogen or hydroxide to the molecule 2-acetylbenzoic acid. The molecule has two functional groups: a carbonyl group and an acetyl group. The chemical structure of this molecule can be seen in the figure below.
2-Acetylbenzoic Acid

Versatile small molecule scaffold

3-Methylbenzo[b]thiophene-2-carboxylic acid (MBTCA) is a heterocyclic compound that is an intermediate in the synthesis of 3-methylthiophene-2-carboxylic acid, a precursor to other drugs. MBTCA is an aerobic, nonpolar compound that has shown antimicrobial activity against some bacteria and fungi. It also has been shown to have practicality as a biomolecular probe for methyl groups in organic solvents. MBTCA can be synthesized by nitration of benzene in the presence of sulfur and sulfoxides. This reaction produces nitrobenzene, which can then be oxidized by potassium permanganate or hydrogen peroxide to produce MBTCA. The most common isomer of MBTCA is 2-(3,5-dimethoxybenzylidene)tetrahydrofuran, with three methyl groups on the

Glycidyltrimethylammonium chloride is a quaternary ammonium compound that has been widely used as a disinfectant and in wastewater treatment. It is mainly used to kill bacteria and viruses, although it can also be used to remove hazardous material from water. Glycidyltrimethylammonium chloride has the ability to inhibit bacterial growth by causing cell membrane damage. This compound is also able to inhibit the synthesis of DNA, RNA, and protein in cells by binding to their respective building blocks. In addition, glycidyltrimethylammonium chloride has cytotoxic effects on human cells and significantly inhibits the replication of oral pathogens.

Chromane-2-carboxylic acid is an amide with a hydroxy group that has inhibitory effects on alkoxyphenols. It has been shown to have the ability to inhibit the growth of cancer cells in mammalian tissue and has been used in synthesizing nitro compounds. Chromane-2-carboxylic acid also inhibits matrix metalloproteinases, which are enzymes that break down proteins in the extracellular matrix and are associated with tumor invasion and metastasis. This compound also has radical scavenging activities, which may be due to its ability to form hydrogen bonds or intramolecular hydrogen bonds with aromatic hydrocarbons or fatty acids.

Versatile small molecule scaffold

CASIN is a lysine-derived antimicrobial agent that inhibits the growth of bacteria by binding to the peptide chains of collagen, which are found in skin and mucous membranes. CASIN has been shown to inhibit the growth of many bacterial species, including those that are resistant to other antibiotics. CASIN can be used for the treatment of infectious diseases caused by bacteria, such as bacterial vaginosis or chlamydia. CASIN has also been shown to reduce body mass index in animal models. The mechanism of action is not known but may involve interference with an enzyme that controls the biosynthesis of fatty acids. The use of CASIN in humans is limited due to its toxicity on human cells and potential safety concerns.

2-(Boc-aminomethyl)benzoic acid is a versatile building block with a wide range of applications in the field of organic chemistry. It has been shown to be useful as a reagent in the synthesis of complex compounds and fine chemicals, as well as a reaction component for the preparation of pharmaceuticals. 2-(Boc-aminomethyl)benzoic acid can also be used as an intermediate in the synthesis of speciality chemicals such as herbicides, pesticides, and fungicides.

(R)-4-Boc-2-methylpiperazine is a picolinamide dehydrogenase inhibitor that is used to treat type 2 diabetes. It has been shown to reduce blood glucose levels in animal models and human subjects with type 2 diabetes mellitus. The mechanism of action is thought to be via inhibition of the 11β-hydroxysteroid dehydrogenase, which increases insulin sensitivity. This drug also has good oral bioavailability, does not cause weight gain, and has an acceptable safety profile.

Versatile small molecule scaffold

Versatile small molecule scaffold

2-Chloro-2-(chlorodifluoromethoxy)-1,1,1-trifluoroethane (HFC-152a) is a chemical compound that belongs to the group of chlorofluorocarbons. It has been used as a refrigerant and aerosol propellant. HFC-152a is an azeotrope with methyl ethyl ketone and ethyl ketone. It has also been reported to have properties as an ether, acetone, and difluoromethyl.

Versatile small molecule scaffold

Versatile small molecule scaffold

Leu-Leu-Leu-OH is a pentapeptide that is used in cancer treatment to inhibit the growth of cancer cells. It prevents the production of proteins and, as a result, cell division. Leu-Leu-Leu-OH has been shown to be effective against tumor cells with an antibody that binds to the surface of cells. The monoclonal antibody is taken up by the cancer cells through receptor mediated endocytosis, which leads to inhibition of protein synthesis and cell death.