Building Blocks

3-Iododibenzofuran is a fluorescent compound that has been used as a probe for the study of neutral endopeptidase activity. The compound is characterized by a high degree of thermal stability and an inhibitory potency at pH 7.0 that is approximately 3 orders of magnitude greater than that of the active site inhibitor, anthracene. 3-Iododibenzofuran can be synthesized using chemoenzymatic methods, with efficiencies and profiles that are similar to those obtained in the conventional method. This probe can also be used to investigate the functional role of proteins in living cells or tissues.
3-Iodobenzofuran has been shown to have pressor effects in rats and can cause tetrazole (a type of explosive) to detonate when heated, which makes it unsuitable for use in devices such as explosives or pyrotechnics.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

4H,5H-Pyrazolo[1,5-a]quinazolin-5-one is a class of heterocyclic compounds that inhibit the parp-1 and parp proteins. These inhibitors are low nanomolar to nanomolar in potency and have been synthesized from chloride and amides. They have been shown to be potent inhibitors of the growth of cancer cells.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

n-Butyrylglycine is a compound that was first identified in human urine as a metabolite of the amino acid glycine. It is an intermediate in the conversion of glycine to succinic acid, which is required for the production of energy in mitochondria. Deficiency of this enzyme causes mitochondrial dysfunction and leads to various metabolic disorders including fatty acid oxidation disorders and homocysteine metabolism defects. n-Butyrylglycine can be detected by gas chromatography or liquid chromatography with mass spectrometry detection.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

1-Ethyl-2-ethynylbenzene is an indene that can be synthesized by the reaction of 1-ethylbenzene with ethynylmagnesium bromide and trifluoroacetyl chloride. 1-Ethyl-2-ethynylbenzene reacts as a nucleophile with electrophiles, such as phenylsulfonyl and acetylene compounds, to form sulfones and acetylenes. It can also react with tetrafluoroborates to form indenes.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

1,3-Diazaspiro[4.4]nonane-2,4-dione (1) is a new fungicide that was shown to have fungicidal activity in vitro against the grapevine pathogens Plasmopara viticola and Plasmopara obducens. This compound has been isolated from the plant Express erythroxylum coca (Erythroxylum coca). The compound belongs to the class of diaza spiro compounds and is a member of a family of diaza spiro compounds with antifungal activity. One possible mode of action for 1 is that it inhibits the synthesis of DNA by binding to bacterial DNA gyrase.

3-Acetylpyrrolidine-2,4-dione is an experimental drug that belongs to the class of metal hydroxides. It has been shown to have anti-tumor activity in vitro and in vivo against a variety of malignant tumors. 3-Acetylpyrrolidine-2,4-dione also inhibits the growth of pigweed and other plants by inhibiting the production of tenuazonic acid. This compound is a tautomeric form of tenuazonic acid, which is also known as 2,4-pentanedione. The carboxylate group on this molecule may be responsible for its herbicidal activity.

2,2,3,3,4,4-Hexafluorobutyric acid is a hydroxylated organic compound. It has been shown to be more chemically stable than other quaternary ammonium compounds. 2,2,3,3,4,4-Hexafluorobutyric acid is used as a polymerization initiator for the preparation of cationic polymers. This chemical can also be used to fragment proteins and nucleic acids in order to prepare samples for analysis by mass spectrometry. 2HFBA is reactive and can cause irritation on contact with the skin or eyes. It has been shown that this chemical may have an effect on body mass index and can bind to calcium ions.

(S)-(+)-1-Bromo-2-methylbutane is a chiral molecule with two stereoisomers, the cis and trans forms. The cis form has been observed to be the more stable of the two. It is a functional theory that these two forms are not mirror images of each other because they have different conformations. (S)-(+)-1-Bromo-2-methylbutane has been used in the synthesis of a number of important molecules. The stereoisomers can be distinguished by conformational analysis and optical microscopy. (S)-(+)-1-Bromo-2-methylbutane also has an application in biotechnology for use as a precursor for hydrazones, which are important in organic chemistry and molecular biology, such as DNA sequencing.

Versatile small molecule scaffold

1,2-Diethylbenzene is a trifluoroacetic acid derivative that is used as an acylation agent and a solid catalyst. 1,2-Diethylbenzene has been shown to increase the energy metabolism in cultured human cells. It also influences fatty acid synthesis and nmr spectra of plant families. 1,2-Diethylbenzene was found to be safe for use in sciatic nerve regeneration in Sprague-Dawley rats with axonopathy. This chemical can also be used as an analytical reagent for the separation of urine samples by liquid chromatography methods.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

3-Bromo-7-methoxy-2H-1-benzopyran-2-one is a coumarin derivative that has been shown to cause liver lesions in rats. The compound can also inhibit locomotor activity, as well as have a significant effect on the levels of serum prolactin. 3-Bromo-7-methoxy-2H-1-benzopyran-2-one is a ligand for the 5HT2 receptor, and it has been suggested that this may be due to its coordination geometry. In addition, 3BMOP binds to DNA with high affinity and specificity, which suggests that it could be used as an antitumor agent.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

3-Hydroxy-5-methylpyridine (3HMP) is a chemical substance that has been classified as an amine. It is a product of the metabolism of purines, which are nitrogenous bases found in DNA and RNA. 3HMP is produced by aerogenic bacteria (such as Enterobacter), and can be used to estimate the number of these bacteria present in water samples. 3HMP has been shown to have antiviral properties against influenza virus, and can be used as a biomarker for the presence of other viruses in animals. 3HMP also has mineralization properties, which have been studied extensively, particularly with regards to pancreatic disease.

1-Hydroxycyclopentane-1-carbonitrile is a monomer that is hydrolyzed to form benzoin and cyanohydrins. It can be used in the production of scifinder as a monomer or dimerizer.

Please enquire for more information about 4,5-Dihydro-1H-imidazol-2-amine hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Versatile small molecule scaffold

2-Bromo-3,3,3-trifluoro-1-propene is a chemical compound that has been synthesized in an asymmetric reaction. The reactant is bromopropane and the product is 2,2,2-trifluoropropene. The methylene group on the propene molecule is activated by the nucleophilic attack of a fluoride ion from hydrogen fluoride to form a cavity with a highly strained bond. The kinetic study of this reaction revealed that the activation energy for the reaction is 42 kJ/mol. Palladium-catalyzed coupling reactions are catalyzed by palladium and require nonpolar solvents such as toluene or dichloromethane. This type of reaction has been shown to be exothermic with an isolated yield of 1%.

4,5-Dihydroxy-2,3-pentanedione is a carbonyl compound that is the product of the oxidation of ascorbic acid. It is used in wastewater treatment and has antimicrobial properties against infectious diseases. This compound has been shown to inhibit protein synthesis by binding to the ribosome and preventing the formation of peptide bonds between amino acids. 4,5-Dihydroxy-2,3-pentanedione has also been shown to bind to plasma proteins, which may be due to its acyl chain structure. 4,5-Dihydroxy-2,3-pentanedione can be synthesized in a catalytic mechanism that involves dehydroascorbic acid and molecular oxygen.

Piperyline is an alkanoic acid that has shown to be effective against skin cancer. It also has antimicrobial properties, which may be due to its ability to bind metal ions and form polymeric compounds. Piperyline inhibits microbial growth by inhibiting the synthesis of proteins and nucleic acids. The antimicrobial activity is related to its cationic polymerization with hydroxyl groups, which forms a structure that can inhibit microbial enzymes and disrupt microbial cell membranes. This compound also interacts with the skin's natural lipids, making it difficult for microorganisms to attach and grow on the skin. Piperyline is synthesized in organic chemistry laboratories as an amide precursor of other pharmaceuticals such as penicillin.