Building Blocks

Applications 1,3-Dimethoxybenzene-d10 (CAS# 340257-57-0) is a useful isotopically labeled research compound.

Applications Bis(2-hydroxyethyl)amine-d11 (CAS# 1219804-08-6) is a useful isotopically labeled research compound.

Applications 1,3-Dimethoxybenzene-2,4,5,6-d4 (CAS# 362049-44-3) is a useful isotopically labeled research compound.

Applications Propiolamide (cas# 7341-96-0) is a compound useful in organic synthesis.

Stability Light Sensitive
Applications 4-(1-Naphthylvinyl)pyridine (cas# 16375-56-7) is a useful research chemical.

Stability Store at -20°C under Argon. Air Sensitive.
Applications 5,5-Diethoxypentanal (cas# 79893-96-2) is a compound useful in organic synthesis.

Applications (±)-2-Ethylhexyl-d17 Acetate (CAS# 1219802-70-6) is a useful isotopically labeled research compound.

Applications n-Dodecyltrimethylammonium-d34 Bromide (CAS# 2259752-12-8) is a useful isotopically labeled research compound.

Applications Tetramethylthiourea (cas# 2782-91-4) is a useful research chemical.

Stability Hygroscopic, Water Sensitive
Applications A useful synthetic intermediate.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications A Nicotinic Acid (N429250) analog used in the preparation of cardiovascular agents and renal drugs.

Applications m-Xylene-alpha,alpha,alpha,alpha',alpha',alpha'-d6 (CAS# 29636-65-5) is a useful isotopically labeled research compound.

Applications o-Vanillic Acid, is a derivative of Vanillic Acid (V097350), used as a flavoring agent. o-Vanillic Acid, is also a building block used for the synthesis of more complex pharmaceutical compounds such as Warfarin (W498500), and Phenprocoumon (P318820).
References Heimark, L. D., J. Labeled Compd. Radiopharm., 23, 137 (198); Kohl, C. et al.: Drug. Metab. Disp., 28, 161 (2000); Hagan, E.C., et al.: J. Am. Pharm. Assoc. Sci. Ed., 42, 379 (1953);

Applications Diethyl Ureidomalonate (cas# 500880-58-0) is a compound useful in organic synthesis.

Applications N,N'-Bis(2-aminoethyl)-1,3-propanediamine-d20 is a useful isotopically labeled compound of N,N'-Bis(2-aminoethyl)-1,3-propanediamine (N497323)

Applications 1,3-Diethynylbenzene (cas# 1785-61-1) is a useful research chemical.

Applications 3,4-Difluoroaniline-2,6-d2 (CAS# 1061566-62-8) can be used in its derivative form as an antiviral agent for Hepatitis B.
References Qiu, Y.L., et.al., U.S. Pat. Appl. Publ., 187,(2019);

Applications (4-Nitrophenyl)propiolic Acid (cas# 2216-24-2) is a compound useful in organic synthesis.

Applications 2,5-Diformylfuran (cas# 823-82-5) is a compound useful in organic synthesis.

Applications 2,6-Difluorobenzonitrile is a halogenated benzonitrile with fungacidal activity. 2,6-Difluorobenzonitrile is the difluoro analogue of the herbicide Dichlobenil.
References Turner, N.J.: Curr. Top. Plant Sci., 50 (1969); Vosahlova, J. et al.: Pest Sci., 49, 303 (1997);

Applications 2-(4-Nitrophenyl)propionic acid is a reagent used in the preparation of α-Methylated analogs of triiodothyroalkanoic acids which have interactions with hepatic thyroid receptors.
References Zemker, N., et al.: J. Med. Chem., 35, 548 (1992);

Applications o-Nitrophenylsulfonyl Chloride is used in the synthesis of renin inhibitors and also anticonvulsants.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Harish, K. et al.: Lett. Drug Des. Disc., 10, 783 (2013); Michida, M. et al.: Org. Proc. Res. Dev., 17, 1430 (2013);

Applications 2,2-Difluoro-2-phenylacetic acid

Applications p-Xylene-d4 (ring-d4) (CAS# 16034-43-8) is a useful isotopically labeled research compound.

Applications 1,10-Dibromodecane-d20 (CAS# 150017-88-2) is a useful isotopically labeled research compound.

Applications 2-Nitropropane-1,1,1,3,3,3-d6 (CAS# 52809-86-6) is a useful isotopically labeled research compound.

Applications 4-(1H-Pyrazol-4-yl)-7-[[2-(trimethylsilyl)ethoxy]methyl]-7H-pyrrolo[2,3-d]pyrimidine is an important intermediate in the preparation of the janus kinase inhibitor INCB018424.
References Lin, Q. et al.: Org. Lett., 11, 1999 (2009);

Applications Intermediate in the production of ABT 737
References Kubota, D., et al.: Bioorg. Med. Chem., 14, 2089 (2006), Park, C., et al.: J. Med. Chem., 51, 6902 (2008),

Applications Pyrazolo[1,5-a]pyrimidine-5-carboxylic acid (cas# 1086375-50-9) is a useful research chemical.

Applications Ethyl (2-Methoxy-2-oxoethyl) Malonate is an intermediate used in the synthesis of Flupyradifurone-d5 (F598616), which is the labeled form of Flupyradifurone (F598615), can be used as an insecticide.
References Anon, IP.com J., 12, 19 (2011)

Applications L-2-Aminopentanoic-4,4,5,5,5-d5 Acid (CAS# 1202936-50-2) is a useful isotopically labeled research compound.

Applications Propionitrile-3,3,3-d3 (CAS# 24300-21-8) is a useful isotopically labeled research compound.

Applications 2,4-Difluorotoluene-3,5,6-d3 (CAS# 1219798-79-4) is a useful isotopically labeled research compound.

Applications Diethyl-d10-amine HBr (CAS# 1219803-53-8) is a useful isotopically labeled research compound.

Applications 1-Pentyne is used as a reagent in the synthesis of a series of novel 1,2,3-triazole-1,4-benzoxazine hybrids which exhibit antiproliferative activity. 1-Pentyne is also used as a reagent in the synthesis of disubstituted isoxazoles which exhibit anti-aging activity.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Koufaki, M., et al.: Eur. J. Med. Chem., 83, 508 (2014); Bollu, R., et al.: Eur. J. Med. Chem., 89, 138 (2015)

Applications 2,2-Dimethylpropionyl-L-carnitine-d3 HCl (N-methyl-d3) is a useful isotopically labeled compound

Applications 2-Propane-d7-thiol (CAS# 1219803-56-1) is a useful isotopically labeled research compound.

Applications Dimethyl Allylmalonate, is a versatile building block used in the synthesis of chemical compounds such as terminal alkyl silane, bromosulfoxide, and diallyl malonates.
References Lee Ky. et al.: Korean Chem. Soc. 25(8), 1280-1282, (2004); Yeun-Min T, et al. Tetrahedron Lett. 31(42), 6047-6050, (1990)

Applications 2-Nitrobenzenesulfonohydrazide (cas# 5906-99-0) is a useful research chemical.

Applications Ethoxybenzene is a reagent used in the synthesis of benzenesulphonylurea derivatives as anti-hyperglycaemic agents and various PTP1B inhibitors.
References Liu, P. et al.: Bioorg. Med. Chem., 23, 7079 (2015);

Applications 4,4'-Dimethoxybenzophenone-d8 (rings-d8) (CAS# 350818-55-2) is a useful isotopically labeled research compound.

Applications Used in the preparation of herbicides.

Applications 4-Ethylpyridine is a general chemical reagent used in the synthesis of substituted pyridines as well as diverse azacyclic compounds.
References Gandhamsetty, N. et al.: J. Am. Chem. Soc., 137, 15176 (2015); Chen, X. et al.: J. Coord. Chem., 68, 2835 (2015);

Applications Pyridine-3-yl-methanesulfonyl Chloride Hydrochloride is used as a reagent in the preparation of methionine derivatives as inhibitors of protein isoprenyl transferases.
References Sebti, S. M., et al.: U.S. 514pp. (2001)

Applications Potassium Hexadecanoate-2,2-d2 (CAS# 203805-86-1) is a useful isotopically labeled research compound.

Applications Potassium Tetradecanoate-2,2-d2 (CAS# 352438-85-8) is a useful isotopically labeled research compound.

Applications 3,5-Dimethoxybenzaldehyde, is a benzaldehyde derivative, that can be used as a building block in the synthesis of more complex structures.
References Frouz, J., et al.: Biodegredation., 22, 1247 (2011); Garcia-Carpintero, E., et al.: Food. Res. Int., 44, 61 (2011);

Applications Potassium Octadecanoate-2,2-d2 (CAS# 352438-86-9) is a useful isotopically labeled research compound.

Applications Potassium Tetradecanoate-d27 (CAS# 352438-87-0) is a useful isotopically labeled research compound.

Applications Dimethyl Hexanedioate-2,2,5,5-d4 (CAS# 76785-05-2) is a useful isotopically labeled research compound.

Applications Potassium Hexadecanoate-d31 (CAS# 63074-47-5) is a useful isotopically labeled research compound.

Applications Dimethyl Hexanedioate-3,3,4,4-d4 (CAS# 55724-08-8) is a useful isotopically labeled research compound.

Applications Dimethyl Hexanedioate-d8 (CAS# 52089-64-2) is a useful isotopically labeled research compound.

Applications N,N-Dimethyl-d6-acetamide (CAS# 31591-08-9) is a useful isotopically labeled research compound.

Applications Ethyl Propargylate is used in the synthesis of substituted anthraquinones. Also used in the preparation of inhibitory pyrazolo[1,5-a]pyridines for anti-inflammatory activity.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Chang, M. et al: Synth. Comm., 43, 3363 (2013); Kojima, A. et al.: Bioorg. Med. Chem. Lett., 23, 5311 (2013);

Applications Dimethyl-1,3-acetonedicarboxylate is used in the preparation of optically active lycorane. It has also been substituted into bispidone derivatives for their use as ligands in PET imaging.
References Yoshizaki, H. et al.: J. Org. Chem., 60, 2016 (1995); Legdali, T. et al.: J. Org. Chem., 77, 11167 (2012);

Applications 1,1,1-Trifluoro-2-iodoethane (cas# 353-83-3) is a compound useful in organic synthesis.

Applications Triethylenetetramine is a selective Cu(II) chelator and crosslinker.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 4-Hydroxy-6-methylpyran-2-one was used in the synthesis of pyrano[3,2-c]pyridones with antiproliferative and apoptosis inducing activities. It was also used in the design of benzisothiazolone human leukocyte elastase inhibitors.
References Magedov, I., et al.: Bioorg. Med. Chem. Lett., 17, 3872 (2007); Hilasta, D., et al.: J. Med. Chem., 38, 4687 (1995)

Applications Tri-n-butyl-d27-amine (CAS# 1219805-78-3) is a useful isotopically labeled research compound.

Applications n-Propyl-d7-amine HCl (CAS# 344298-88-0) is a useful isotopically labeled research compound.

Applications 3-Hydroxypiperidine is used as a reagent to synthesize trisubstituted ureas, compounds that act as thrombin receptor (PAR-1) antagonists. 3-Hydroxypiperidine is also a metabolite of Piperidine (P479985), Piperidine is an organic heterocyclic amine widely used as building block and reagent in the synthesis of organic compounds including pharmaceuticals.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Barrow, J., et al.: Bioorg. Med. Chem. Lett., 11, 2691 (2001); Reshmi, S.K., et al.: J. Med. Plant. Res., 4, 1535 (2010); Wiles, J.A., et al.: J. Med. Chem., 54, 3418 (2011);

Applications (±)-2-Hydroxyhexanoic-6,6,6-d3 Acid (CAS# 1219798-84-1) is a useful isotopically labeled research compound.

Applications 7-Hydroxy-1-indanone (cas# 6968-35-0) is a useful research chemical.

Applications Ibrutinib Dimer is a dimer impurity of Ibrutinib (I124970), a highly selective Bruton’s tyrosine kinase (Btk) irreversible inhibitor.
References MacGlashan, D., et. al.: Int. Immunol., 11, 475 (2011)

Applications Trimethylphenyltin is an activator for visible light-induced polymerization of vinyl monomers sensitized by photoreducible dyes.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Eaton, D.F.: Photogr. Sci. Eng., 23, 150 (1979)

Applications 3,4,5-Tribromotoluene (cas# 73557-59-2) is a useful research chemical.

Applications 2,4,5-Tribromotoluene (cas# 3278-88-4) is a useful research chemical.

Applications N,N,N'-Trimethyl-d6-1,3-propanediamine (N,N-dimethyl-d6) (CAS# 1219803-54-9) is a useful isotopically labeled research compound.

Applications 4'-(Imidazol-1-yl)acetophenone (cas# 10041-06-2) is a useful research chemical.

Applications 4-Hydroxy-3-methyl-benzophenone (cas# 5326-42-1) is a useful research chemical.

Applications N-(1H-Indol-5-yl)benzamide is a octamer-binding transcription factor 4 activating compound that activated Oct4 and Nanog promoters, which are essential regulators of embryonic stem cell (ESC) pluripotency and key to the reprogramming process.
References Li, W.D., et al.: Proceed. Nation. Acad. Sci. U.S.A., et al.: 109, 20853 (2012);

Stability Hygroscopic, Moisture Sensitive
Applications Tosyl cyanide is a compound used as a cyanating and acylating agent in synthetic chemistry. Tosyl cyanide is also used as a reagent to synthesize cyanobutadiyne, a linear compound that is naturally found in various interstellar molecular clouds.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Abbas, S. & Haines, A.: Carb. Res., 39, 358 (1975); Kirby, C., et al.: J. Mol. Spec., 83, 261 (1980); Skerlj, R., et al.: Bioorg. Med. Chem. Lett., 21, 262 (2011)

Applications Omeprazole intermediate.
References Bazemore, R., et al.: J. Agric. Food Chem., 54, 497 (2006), Kasibhatla, S., et al.: J. Med. Chem., 50, 2767 (2007),

Applications 5-(Hydroxymethyl-d2)uracil-6-d1 (CAS# 352438-73-4) is a useful isotopically labeled research compound.