Building Blocks

Applications trans-2-Hexenal is an unsaturated aldehyde that has an apple odour. trans-2-Hexenal is produced by soybean plants, and is also a sex pheromone produced by the female polyphemus moth.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Corbo, M., et al.: J. Agr. Food Chem., 48, 2401 (2000); De Lucca, A., et al.: J. Food Sci., 76, M381 (2011); Riddiford, L.: Science, 158, 139 (1967)

Applications 4'-Chloroacetophenone-2',3',5',6'-d4 (CAS# 284474-50-6) is a useful isotopically labeled research compound.

Applications 1-Pentyne is used as a reagent in the synthesis of a series of novel 1,2,3-triazole-1,4-benzoxazine hybrids which exhibit antiproliferative activity. 1-Pentyne is also used as a reagent in the synthesis of disubstituted isoxazoles which exhibit anti-aging activity.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Koufaki, M., et al.: Eur. J. Med. Chem., 83, 508 (2014); Bollu, R., et al.: Eur. J. Med. Chem., 89, 138 (2015)

Applications Sodium n-Octyl-d17 Sulfate (CAS# 1219802-16-0) is a useful isotopically labeled research compound.

Applications 4-(2-Chloroethyl)-N-methoxy-N,α,α-trimethyl-benzeneacetamide is an impurity of Bilastine (B385000), which is a novel, nonsedating H1-antihistamine developed for symptomatic treatment of allergic rhinitis and chronic idiopathic urticaria.
References Van Cauwenberge, P., et al.: Clin. Exp. Allergy, 30, 891 (2000), Bauchau, V., et al.: Eur. Respir. J., 24, 758 (2004), Lehman, J., et al.: Drugs, 66, 2309 (2006),

Applications Sodium Octadecanoate-d35 (CAS# 1219794-97-4) is a useful isotopically labeled research compound.

Stability Extremely Moisture Sensitive
Applications Hexylphosphonic Dichloride acts as a reagent for the preparation of enantiomeric phosphonates which are inhibitors of cholesterol esterase.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Gillespie, S. G., et al.: Phosphorus, Sulfur Silicon Relat. Elem., 122, 205 (1997)

Applications Chlorsulfonyl Isocyanate, is a versatile reagent in organic sythesis, by having two electrophilic sites. It can be used in the snthesis of β-lactams.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Miller, M.J., et al.: "Encyclopedia of Reagents for Organic Synthesis" (2005);

Applications Used in the preparation of optically pure L-(+)-Ergothioneine.
References Lehn, J., et al.: Science, 291, 2331 (2001), Nicoll, A., et al.: Org. Biomol. Chem., 2, 2175 (2004),

Applications 1,1,1-Trifluoro-2-iodoethane (cas# 353-83-3) is a compound useful in organic synthesis.

Applications 1,3-Diethynylbenzene (cas# 1785-61-1) is a useful research chemical.

Applications 4-Chloro-1H-pyrrolo[3,2-c]pyridine is an intermediate used in the synthetic preparation of potent gp120-CD4 inhibitors.
References Tran, T.D., et al.: Bioorg. Med. Chem. Lett., 19, 5250 (2009); Kim, J.T., et al.: J. Am. Chem. Soc., 129, 3027 (2007);

Applications Sodium Octanoate-d15 (CAS# 56408-90-3) is a useful isotopically labeled research compound.

Applications L-Methionine-d3 (S-methyl-d3) Methyl-d3 Sulfonium Chloride (CAS# 362049-54-5) is a useful isotopically labeled research compound.

Applications N,N-Dimethyl-d6-tetradecylamine is a useful isotopically labeled compound of N,N-Dimethyltetradecylamine (D479480)

Applications 1,3,5-Triphenylbenzene-d18 (CAS# 34496-33-8) is a useful isotopically labeled research compound.

Applications HS-173 is a potent PI3Kα inhibitor with anticancer activity.
References Kim, O., et al.: J. Med. Chem., 54, 2455 (2011); Lee, H., et al.: Cancer Lett., 328, 152 (2013)

Applications Allylboronic acid pinacol ester
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications N,N'-Bis(2-aminoethyl)-1,3-propanediamine-d20 is a useful isotopically labeled compound of N,N'-Bis(2-aminoethyl)-1,3-propanediamine (N497323)

Applications Diethyl Ureidomalonate (cas# 500880-58-0) is a compound useful in organic synthesis.

Applications (3-Nitrophenyl)acetic Acid is a useful synthetic intermediate.
References Strazzolini, P., et al.: J. Org. Chem., 63, 952 (1998)

Applications 4-Nitrophenylacetonitrile is used as a radical inhibitor in the polymerization of vinyl acetate. Toxic compound to tetrahymena pyriformis.
References Foldes-Berezhnykh, T. et al.: Eur. Polym. J., 8, 1237 (1972); Cronin, M. et al.: Chem. Res. Tox., 14, 1498 (2001);

Applications 5’-O-(4,4’-Dimethoxytrityl)thymidine (cas# 40615-39-2) is a compound useful in organic synthesis.

Applications Hydrazine derivative.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 4-Chloro-1-methylpiperidine is a reactant in the synthesis of indole and benzimidazole piperazines as histamine H4 receptor antagonist.
References Terzioglu, N., et. al.: Bioorg. Med. Chem. Lett., 14, 5251 (2004)

Applications 3-Hydrazinyl-6-(trifluoromethyl)pyridazine can be a starting material in the synthesis of 6-(Trifluoromethyl)-1,2,4-triazolo[4,3-b]pyridazine.
References Wan, W., et al.: Tetrahedron, 65(21), 4212-4219; 2009

Applications D-Methionine-d3 is used for detection D- and L-enantiomers of methionine and [2H3]methionine in plasma by gas chromatography-mass spectrometry of methylated/N-acylated derivatives.
References Hasegawa, H., et al.: J. Chromatogr. B: 823, 203 (2005);

Applications 4-Chloro-2-methylphenol-3,5,6-d3,OD (CAS# 1219804-06-4) is a useful isotopically labeled research compound.

Applications N-3-(Sulfopropyl)-3-methoxy-5-methylaniline is used as a reagent for the evaluation of basic property and long-term stability of reagents for enzymically assaying triglyceride, cholesterol and uric acid.
References Yamaguchi, T., Iryo to Kensa Kiki-Shiyaku., 3, 591-597 (2007).

Applications 4-Bromochlorobenzene-d4 (CAS# 134415-42-2) is a useful isotopically labeled research compound.

Applications Trimethylphenyltin is an activator for visible light-induced polymerization of vinyl monomers sensitized by photoreducible dyes.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Eaton, D.F.: Photogr. Sci. Eng., 23, 150 (1979)

Applications DL-Methionine-2-d1 (CAS# 67866-74-4) is a useful isotopically labeled research compound.

Applications 3-chloro-1-(4-methylphenyl)propan-1-one is a reagent used in the synthesis of Mannich base-type derivatives which can be used in the treatment of chagas disease.
References Martin-Escolano, R. et al.: J. Med. Chem., 61, 5843 (2018);

Applications 8-Chloro-3-methoxy-11-(1-methyl-4-piperidinyl)-6,11-dihydro-5H-benzo[5,6]-cyclohepta[1,2-b]pyridin-11-ol (cas# 165739-71-9) is a compound useful in organic synthesis.

Applications 2-Methyl-d3-2-hexanol-1,1,1,3,3-d5 is a useful isotopically labeled compound of 2-Methyl-2-hexanol (M331848)

Applications 2-Amino-3-pyridinecarbonitrile is used as a reagent in the synthesis of novel imidazo[1,2-a]pyridine derivatives as potent c-Met inhibitors and antimycobacterials.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Li, C., et al.: ACS Med. Chem. Lett., 6, 507 (2015); Ramachandran, S., et al.: Bioorg. Med. Chem. Lett., 23, 4996 (2013)

Stability Hygroscopic, Water Sensitive
Applications A useful synthetic intermediate.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 5-Hexen-1-ol is a volatile organic compound that can be found in Brazilian chilli peppers (Capsicum spp.).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Bogusz, S.Jr., et al.: Food Res. Int., 48, 98 (2012)

Stability Hygroscopic
Applications 2-Aminopyrimidine-5-boronic acid

Applications 2-Amino-4-(trifluoromethyl)benzenethiol Hydrochloride can be used as reactant/reagent in preparation of fused benzo-diazepinones/oxazocinone/thiazapines/diazapines/diazocins/thiazine/indoles via CuI-L-proline catalyzed SN2 reaction.
References Srinivasulu, V., et al.: Tetrahedron, 73, 2139 (2017)

Stability Hygroscopic
Applications 2,4-Dichloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine hydrochloride (cas# 1187830-76-7) is a useful research chemical.

Applications Labelled 3-(3,4-Dimethoxyphenyl)propanoic Acid (D460730), one of the novel circulating coffee metabolites in human plasma.
References Clifford, M., et al.: J. Sci. Food Agric., 80, 1033 (2000), Mateos, R., et al.: J. Agric. Food Chem., 54, 8724 (2006), Wong, C., et al.: J. Nutr. Biochem., 21, 1060 (2010),

Applications 1-Hydroxycyclopentanecarboxylic Acid is a reagent used in the preparation of pyridone-conjugated monobactam antibiotics showing gram-negative activity.
References Brown, M. et al.: J. Med. Chem., 56, 5541 (2013); Rozhko, E. et al.: ChemCatChem., 5, 1998 (2013);

Applications N,N-Dicyclohexylmethylamine is used as a reagent in the base preparation of 13C2- and 2H phenethylamines as internal standards for IDMS by Pd-catalyzed double carbonylation of aryl iodides in the presence of amine nucleophiles followed by deoxygenation.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Nielsen, D., J. Org. Chem., 74, 6155 (2012)

Applications N-Methyl-d3-glycine-2,2-d2 HCl (CAS# 1219794-62-3) is a useful isotopically labeled research compound.

Applications 1-(1-phenylcyclobutanecarbonyl)piperidine-4-carboxylic acid (cas# 1099048-69-7) is a useful research chemical.

Applications 2-Methoxybenzene-1,4-diol (cas# 824-46-4) is a useful research chemical.

Applications 2,6-Dichloro-4-nitroanisole (cas# 17742-69-7) is a useful research chemical.

Applications 3,4-Dichlorobenzoic-d3 Acid (CAS# 350818-53-0) is a useful isotopically labeled research compound.

Applications Eicosanoic-2,2-d2 Acid (CAS# 232600-70-3) is a useful isotopically labeled research compound.

Applications Dimethylthiocarbamoyl Chloride is used as a reagent in the synthesis of Fluticasone Propionate (F599500); an anti-allergic, anti-asthmatic, and anti-inflammatory agent.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Meltzer, E.O., et al.: J. Allergy Clin. Immunol., 86, 221 (1990); Mitchison, H.C., et al.: Gut, 32, 260 (1991); Phillipps, G.H., et al.: J. Med. Chem., 37, 3717 (1994)

Applications 3-(Methylamino)propanoic acid HCl

Applications Potassium Octadecanoate-2,2-d2 (CAS# 352438-86-9) is a useful isotopically labeled research compound.

Applications 5-Hydroxyisophthalic Acid is used as a reagent in the synthesis of silver carboxylate metal organic framework (MOF) complexes. 5-Hydroxyisophthalic Acid is also used as the starting material in the synthesis of N,N’-Bis(2,3-dihydroxypropyl)-5-[(N-(2-hydroxyethyl)carbamoyl)methoxy]-2,4,6-triiodoisophthalamide (B426310); a compound related to Ioversol( I737000) which is a nonionic, low osmolality, radiographic contrast agent.
References Lu, X., et al.: J. Inorg. Biochem., 138, 114 (2014); Wilkins, R.A., et al.: Invest. Radiol., 24, 781 (1989); Kaufman, A.J., et al.: Urol. Radiol., 12, 56 (1990)

Applications Methyl 4-amino-2-fluorobenzoate

Stability Store FROZEN
Applications Material that was assayed to be approximately 80% pure was diluted to 5% in benzene.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications Malonamide is used in the synthesis of malonamic acid, malonamate and malonamide derivative of some heterocyclic compounds with antiinflammatory activity.
References Katagi T., et al.: Chem. Pharm. Bull., 33, 4878 (1985);

Applications 2-phenylcyclopentan-1-one (cas# 1198-34-1) is a useful research chemical.

Applications Eicosanoic-17,17,18,18-d4 Acid (CAS# 1219803-69-6) is a useful isotopically labeled research compound.

Impurity Metronidazole EP Impurity B
Applications Antibiotic substance produced by an unidentified Streptomyces.
References Maeda, et al.: J. Antibiot., 6A, 182 (1953),

Applications 1-Bromohexadecane-16,16,16-d3 (CAS# 284474-40-4) is a useful isotopically labeled research compound.

Applications 1-Bromohexadecane-d33 (CAS# 284474-41-5) is a useful isotopically labeled research compound.

Applications 1-Bromohexadecane-1,1,2,2-d4 (CAS# 1219805-65-8) is a useful isotopically labeled research compound.

Applications p-Azoxyanisole-d6 (O,O-dimethyl-d6) (CAS# 34172-21-9) is a useful isotopically labeled research compound.

Applications 1-Bromoheptane-d15 (CAS# 98195-42-7) is a useful isotopically labeled research compound.

Applications 1-Iodooctane-1,1-d2 (CAS# 89232-08-6) is a useful isotopically labeled research compound.

Applications Methyl 6-aminopyridazine-3-carboxylate

Applications 1-Bromoheptane-7,7,7-d3 (CAS# 344253-18-5) is a useful isotopically labeled research compound.

Applications 2-Bromonaphthalene

Applications 2-Benzoylpyrrole (cas# 7697-46-3) is a compound useful in organic synthesis.

Applications 4-Methyl-2-pentanol-1,1,1-d3 is a useful isotopically labeled compound of 4-Methyl-2-pentanol (M324750)
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications Ethyl-d5 Methanesulfonate (CAS# 1219795-44-4) is a useful isotopically labeled research compound.

Applications 4-Piperidinemethanol, is a building block that can be used for the synthesis of selective inhibitors of sphingosine kinase 1 (SK1), that may serve as therapeutic agents for proliferative diseases, including hypertension.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Baek, D., et al.: Chem.l Commun., 49, 2136 (2013);