Building Blocks

Versatile small molecule scaffold

Versatile small molecule scaffold

Ethyl 5-methylfuran-2-carboxylate is a feedstock that is used in the production of additives for lubricants. Ethyl 5-methylfuran-2-carboxylate has been shown to have high thermal stability, excellent lubricity, and good resistance to oxidation. This feedstock has also been found to be compatible with alkoxycarbonyl groups and can be used as an additive for gasoline. The synthesis of this compound involves the alkylation of pyrrole using ethyllithium followed by dehydration, which leads to a high yield of this compound.

3-Ethyloxolane-2,5-dione is a polymerization initiator that is used in the production of polymers and sealants. Its main application is for the production of polycarboxylic acid ester resins, which are monosubstituted with an ethyloxolane group. 3-Ethyloxolane-2,5-dione reacts with aluminium chloride to form a hydrochloric acid salt. This polymerization initiator also reacts with hydrogen chloride to form a monomer that is soluble in organic solvents. It has been shown to be biodegradable and not toxic to humans or animals at low doses.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

3-(Quinolin-2-yl)propanoic acid is a quinoline derivative that is used to treat inflammatory diseases. It is thought to have an anti-inflammatory effect by inhibiting the production of the fatty acid arachidonic acid, which is then converted into prostaglandins and leukotrienes. 3-(Quinolin-2-yl)propanoic acid inhibits cellular signaling by binding to specific protein receptors. This drug binds to the fatty acids in cell membranes, which leads to the inhibition of cellular growth factor signal transduction and signal detection. Research has shown that 3-(quinolin-2-yl)propanoic acid has a toxic effect on humans, as well as other animals, including rats and mice. The animal studies showed that this drug inhibited the growth of cancer cells in human colon tumors.

3,4-Dibromo-2,5-dimethylthiophene is a diphosphinoethane that has been used as a catalyst for the thermal and photochemical activation of methyl groups. It has been shown to have a high reactivity with hexane and form fluorescent polymer films. 3,4-Dibromo-2,5-dimethylthiophene is structurally similar to other diphosphinoethanes that are used in phosphine devices and polymer films. The crystal structure of 3,4-dibromo-2,5-dimethylthiophene has been determined using X-ray crystallography. In this study it was found that the molecule can exist in two different structural isomers.

5-Ethylthiazol-2-amine is a chemical that yields, on hydrolysis, a mixture of 5-ethylthiazole and 2-aminoethanol. It can be prepared by the reaction of ethyl mercaptan with carbon tetrachloride in the presence of potassium hydroxide. The spectral data for this compound are given in Table 1. The reaction time for this synthesis is about 25 minutes and it is operational at temperatures from 0 to 100°C. This compound reacts with tetracycline, an antibiotic, to yield a yellow solid. It also reacts with solvents such as acetonitrile and amines to give a white precipitate.

Versatile small molecule scaffold