Building Blocks

Applications 2-Oxa-7-azaspiro[3.5]nonane is an intermediate used to prepare benzothienoazepine derivatives as potent respiratory syncytial virus RNA polymerase inhibitors. It is also used to prepare 1,7-Diazacarbazole derivatives as inhibitors of checkpoint kinase 1.
References Xiong, H., et al.: Bioorg. Med. Chem. Lett., 23, 6789 (2013); Gazzard, L., et al.: J. Med. Chem., 58, 5053 (2015)

Applications 1-Pentane-d11-thiol is a useful isotopically labeled compound of 1-Pentanethiol (P274053)
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 4-Nitrobenzyl Bromide is used in the synthesis of di and tri-substituted azoles. Also used in the preparation of N6-Benzyladenosine-5’-uronamides as selective A3 adenosine agonists.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Gallo-Rodriguez, C. et al.: J. Med. Chem., 37, 636 (1994); Appukkuttan, P. et al.: Org. Lett., 6, 23 (4223);

Applications N-(ethoxymethyl)-N-(2-ethyl-6-methylphenyl)acetamide (cas# 162102-65-0) is a useful research chemical.

Applications 2-[(Dipropylamino)sulfonyl]benzoic Acid, is a building block used in various chemical synthesis.

Applications Methyl 6-Chloronicotinate is used in the determination of Acetamiprid (A150800) and its metabolites in crop and soil.
References Tokieda, M., et al.: Nippon Noyaku Gakkaishi, 24, 115 (1999)

Applications Sodium Octadecanoate-d35 (CAS# 1219794-97-4) is a useful isotopically labeled research compound.

Applications 2-(4-Nitrophenyl-d4)propane (CAS# 1219803-36-7) is a useful isotopically labeled research compound.

Applications Homoveratric Acid is a dopamine metabolite that inhibits brain mitochondrial respiration via monoamine oxidase/H2O2-dependent or non-dependent pathway.
References Gluck, M.R. et al.: J. Neurochem., 91, 788 (2004); Morikawa, N. et al.: J. Neurochem., 66, 1174 (1996); Goodwin, B.L. et al.: Xenobiotica, 24, 129 (1994);

Applications Sodium Octanoate-d15 (CAS# 56408-90-3) is a useful isotopically labeled research compound.

Applications 2-Hydroxy-3-methyl-butanedioic Acid is used as a sole C source when metabolized by soil bacterium; Also, it is an intermediate used in the synthesis of 5-Methyl-2’-deoxy Cytidine-13C,15N2 (M295904), which is an isotopic analog of 5-Methyl-2’-deoxy Cytidine (M295900), a Cytidine (C998300) analog and also an isostere of Thymidine (T412000).
References Nakano, H., et al.: J. Biochem., 70, 429-440 (1971); Sabini, E., et al.: J. Med. Chem., 51, 4219 (2008), Sabini, E., et al.: J. Mol. Biol., 378, 607 (2008)

Applications 4-n-Butylanisole-2,3,5,6-d4 (CAS# 1219804-78-0) is a useful isotopically labeled research compound.