Building Blocks

Versatile small molecule scaffold

2-Chloro-4,5-dimethoxybenzaldehyde is a functional group that can be used as a nucleophile in organic synthesis. It has been shown to react with amines to produce nitro compounds. This functional group also reacts with acidic substances such as malic acid and ethanol extractions, forming chlorinated products. 2-Chloro-4,5-dimethoxybenzaldehyde can be extracted from the surface of plants using piperazine or morpholine.

Phenylhydrazine is a white crystalline solid with a molecular weight of 150.25, and the molecular formula C6H5NHN. It is soluble in water, alcohol, ether and chloroform. Phenylhydrazine can react with an acid chloride to form a hydrazone; this reaction is used in the synthesis of some pharmaceuticals. The most common use of phenylhydrazine is as a precursor to various pharmaceuticals, such as antipyretics and anti-inflammatory agents. Phenylhydrazine reacts with zinc chloride to form 1-(5-methyl-1H-pyrazol-4-yl)ethanone.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

2-Phenylfuro[3,2-b]pyridine (2PFBP) is a synthetic compound that has antibacterial activity. It is a stereoselective compound, which means it selectively binds to one of the two enantiomers of an enzyme. The selectivity of 2PFBP for methicillin-resistant Staphylococcus aureus (MRSA) was demonstrated in a study using mcf-7 cells, which are human cancer cells that have been transformed by the gene encoding methicillin resistance. The compound inhibited MRSA cell growth and induced apoptosis in MRSA cells. 2PFBP also has antibacterial activity against other bacteria such as S. aureus and S. epidermidis strains. 2PFBP inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

2-(Chloromethyl)-3,5-dioxahex-1-ene is a synthetic compound that belongs to the group of piperidine compounds. It is a nucleophile and a primary amine that reacts with carbonyl compounds in an efficient method. This reaction is stereoselective and produces the corresponding 2-(chloromethyl)-3,5-dioxahex-1-enes. The chloride ion can be replaced by other nucleophiles such as methoxymethyl or amines. The malonate ester can also be used for this reaction.
2-(Chloromethyl)-3,5-dioxahex-1-ene has been shown to react with phenylacetonitrile and chloride ions to produce alkylated products such as 2-(chloromethyl)-3,5-dioxahexanenitrile or 2-(chloromethyl)-4,6-diox

N-(2-Amino-phenyl)-isonicotinamide is a compound that has various characteristics and potential applications. It has been studied for its interaction with dopamine, as well as its ability to react with methanol and hydrogen atoms. This compound also exhibits amide properties and has been investigated in the development of DNA vaccines. Additionally, it has shown cytotoxic effects on multidrug-resistant cells and demonstrated potential as a catalyst in reactions involving diphenyl ether and guanidine. Furthermore, N-(2-Amino-phenyl)-isonicotinamide has been explored in research related to ornithine, tripterygium, ammonium salts, and tetrachloride. Its diverse characteristics make it an intriguing compound for further study and potential applications.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold