Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>5-Phenylpyrazolidin-3-one is a pyrazole compound that has a tautomeric form. It has been shown to selectively interact with anions, such as chloride anion, in the presence of hydrogen bonds. This leads to the production of a hydrogen cation and an electrophilic imine. 5-Phenylpyrazolidin-3-one is used in chemosensors for the detection of various chemicals, including formaldehyde and acetaldehyde. 5-Phenylpyrazolidin-3-one also has antitumor activity due to its ability to inhibit DNA synthesis and induce apoptosis in cancer cells.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>5F-203 is a new chemical entity that has been shown to inhibit the function of cytochrome P450 1A1 (CYP1A1), which is involved in the metabolism of many substances, including drugs. It also inhibits the function of mitochondrial membrane potential and promotes reactive oxygen species production. These effects are thought to be responsible for its anticancer activity. 5F-203 has been studied in cancer cells and breast cancer cells with low potency. The biological properties of 5F-203 have not been determined yet.</p>

<p>Versatile small molecule scaffold</p>

<p>2-Oxononanoic acid is a fatty acid that inhibits the binding of diagnostic agents to interleukin receptors. 2-Oxononanoic acid has been shown to inhibit the production of reactive oxygen species, which may be due to its acidic pH. This compound also inhibits the release of inflammatory mediators, such as cytokines and arachidonic acid metabolites. 2-Oxononanoic acid has been shown to have therapeutic potential in autoimmune diseases and infectious diseases, such as HIV/AIDS. 2-Oxononanoic acid is an affinity ligand for fatty acids and can be used in conjugates with antibodies or antigens for diagnostic purposes or therapy.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>5-Bromo-6-hydroxypyrimidine-4-carboxylic acid is a homologous organic acid that is used as a pharmaceutical preservative. It is most commonly found in acidic pharmaceutical formulations. 5-Bromo-6-hydroxypyrimidine-4-carboxylic acid inhibits the growth of bacteria and fungi by acting as an enzyme inhibitor. The inhibition of enzymes such as lactamase, which breaks down the lactam ring in penicillin, prevents bacterial and fungal growth by preventing them from breaking down their natural cell walls. 5-Bromo-6-hydroxypyrimidine-4-carboxylic acid has also been shown to have potent anticancer activity in the lab setting, although the clinical significance of this has not yet been determined.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>5-Iodo-1-benzofuran is an organic compound with a linear structure and a phenyl group. It has one hydrogen bond, two of which are stabilized by the phenyl ring. The other three hydrogen bonds are stabilized by the halogen bonds. The benzofuran ring is rotated in such a way that the substituents on it are dihedral. 5-Iodo-1-benzofuran has been shown to have a crystal structure that is stabilized by the halogen bond between the phenyl group and iodine.</p>

<p>3-Chloro-N-methyl-2-nitroaniline is an antibiotic that belongs to the group of quinolone antibiotics. It has a broad spectrum against Gram-positive and Gram-negative bacteria, including methicillin resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa. 3-Chloro-N-methyl-2-nitroaniline binds to bacterial DNA gyrase and topoisomerase IV, as well as human DNA gyrase and topoisomerase II, inhibiting their activity. This leads to cell death by interfering with the production of proteins vital for cell division. The optimal parameters for this drug have been found using isothermal titration calorimetry on the enzyme gyrase in the presence of different concentrations of 3CMA. Pharmacological targets for this drug include DNA gyrase and topoisomerase IV.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>N-(Carbamothioylamino)furan-2-carboxamide is a chemical compound that has been used as a liver protectant and to treat calcium deficiencies. The calcium salt of the drug is prepared by mixing anhydrous ethanol with calcium chloride and adding pyridine dropwise. Upon refluxing, the mixture is cooled and then evaporated under vacuum to yield the desired product.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Chrysanthemic acid is a chiral molecule that has been shown to have anti-inflammatory properties. The hydroxyl group in the molecule reacts with malonic acid, forming a chrysanthemic ester. Chrysanthemic acid is also known as an analytical method for determining the degree of unsaturation of fatty acids. Chrysanthemic acid is used in the synthesis of monoclonal antibodies, which can be applied for the treatment and prevention of diseases such as cancer, rheumatoid arthritis, Crohn's disease, and other autoimmune disorders. It can also be used to treat infections caused by bacteria that are resistant to antibiotics. The basic structure of chrysanthemic acid is an inorganic acid that contains a hydroxyl group and an asymmetric carbon atom.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Benzeneacetic acid, 3,5-difluoro-hydroxy-, (S)- is a ligand that can bind to transition metals such as copper or iron. It has been shown to be a good sensing ligand for the detection of mandelate and enantioselective for the synthesis of chiral molecules. The divalent bonding between the benzeneacetic acid and the metal may be due to coordination or dipyridyl. The stability of this molecule is also dependent on the type of metal it is bonded with.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>7-Bromo-5-nitroindoline is a synthetic compound that has been shown to bind to auxin, which is a plant hormone. It has been used in photoaffinity labeling and can be used in the synthesis of other compounds. 7-Bromo-5-nitroindoline binds reversibly and covalently to auxin in the presence of light. The regiospecificity of this binding allows for the determination of specific properties of auxin binding. 7-Bromo-5-nitroindoline is also used as a tritiated label in syntheses and as a deuterated label for photoaffinity labeling.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-Methylbenzo[b]thiophene-2-carboxylic acid (MBTCA) is a heterocyclic compound that is an intermediate in the synthesis of 3-methylthiophene-2-carboxylic acid, a precursor to other drugs. MBTCA is an aerobic, nonpolar compound that has shown antimicrobial activity against some bacteria and fungi. It also has been shown to have practicality as a biomolecular probe for methyl groups in organic solvents. MBTCA can be synthesized by nitration of benzene in the presence of sulfur and sulfoxides. This reaction produces nitrobenzene, which can then be oxidized by potassium permanganate or hydrogen peroxide to produce MBTCA. The most common isomer of MBTCA is 2-(3,5-dimethoxybenzylidene)tetrahydrofuran, with three methyl groups on the</p>

<p>Versatile small molecule scaffold</p>

<p>2-Bromo-3,3,3-trifluoro-1-propene is a chemical compound that has been synthesized in an asymmetric reaction. The reactant is bromopropane and the product is 2,2,2-trifluoropropene. The methylene group on the propene molecule is activated by the nucleophilic attack of a fluoride ion from hydrogen fluoride to form a cavity with a highly strained bond. The kinetic study of this reaction revealed that the activation energy for the reaction is 42 kJ/mol. Palladium-catalyzed coupling reactions are catalyzed by palladium and require nonpolar solvents such as toluene or dichloromethane. This type of reaction has been shown to be exothermic with an isolated yield of 1%.</p>

<p>2-Phenoxyaniline is a nitro compound that can be converted to the corresponding palladium complexes. It is an inhibitor of the acylation reaction, which is a type of chemical reaction in which an organic molecule reacts with an acid. The inhibition of this reaction has been shown to have an effect on heart disease, specifically by lowering cholesterol levels and reducing atherosclerosis. 2-Phenoxyaniline has also been shown to inhibit the activation energy for electron transfer reactions, making it useful as a catalyst in analytical methods. 2-Phenoxyaniline also undergoes vibrational spectroscopy when exposed to liquid chromatography and other analytical methods.</p>