Building Blocks

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>3-Methylmorpholine-2,5-dione is an organic compound with the chemical formula CH3N(CH2)6CH3. It has a molecular weight of 118.14 g/mol and a transition temperature of -78.4 °C. 3-Methylmorpholine-2,5-dione is a colorless oily liquid that is soluble in water and ethanol. It can be used to synthesize polymers such as polymethyl methacrylate (PMMA), polyvinyl chloride, polypropylene, ethylene oxide, and ethylene glycol. 3-Methylmorpholine-2,5-dione can also be used as a polymerization initiator for ring opening polymerizations with stannous octoate or triisobutylaluminum.</p>

2-(2-Aminopropyl)phenol is a drug that can be used to treat jaundice. It is an antidote for the treatment of acute and chronic liver disease, including cirrhosis and hepatitis. 2-(2-Aminopropyl)phenol is used to lower blood bilirubin levels in people with high bilirubin levels, such as those with hemolytic disorders or Gilbert's syndrome. This drug also has been shown to reduce the risk of reoccurrence of breast cancer in women who have undergone surgery for this condition. 2-(2-Aminopropyl)phenol binds to serum proteins and may also bind to albumin and haptoglobins in the blood. This compound has a low affinity for erythrocytes and does not affect red blood cells.

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>5-Chloro-3-methyl-1-(pyridin-2-yl)-1H-pyrazole-4-carbaldehyde is an organic compound that belongs to the class of substituted phenyl amides. It has a melting point of 187 degrees Celsius, and crystallizes in a centrosymmetric form. This substance reacts with nucleophiles through the hydrogen bonds present in its structure. The substituent on the phenyl group can be electron withdrawing or electron donating, which affects the reactivity. 5-Chloro-3-methyl-1-(pyridin-2-yl)-1H-pyrazole-4-carbaldehyde is useful for condensation reactions and can also form dimers that are stabilized by hydrogen bonding.</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

2-Benzylmorpholine is a chiral compound that is an amine and a structural isomer of morpholine. It has been shown to be a pharmacokinetic suppressant in chronic oral studies, and the profile of the drug is similar to those of other amines. The enantiomer of 2-Benzylmorpholine has been shown to have a more potent interaction with epoxidation than its counterpart, which may lead to different pharmacological properties.

<p>2-Formylbenzamide is a molecule that has been shown to have inhibitory effects on inflammatory diseases and cancer. It has been shown to reduce the growth of cells by inhibiting the production of inflammatory cytokines, such as tumor necrosis factor (TNF), interleukin-1β, and interleukin-6. 2-Formylbenzamide also inhibits the proliferation of cancer cells in vitro. This compound can be used for detection because it can be allylated, which makes it detectable using electron capture negative ion mass spectrometry. 2-Formylbenzamide can be used as a bioelectronic sensor for monitoring the levels of TNF and IL-6 in patients with inflammatory disease or cancer.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>6-Chloro-5-methyl-2,3-dihydro-1H-indole is a 5HT receptor agonist that has been shown to be an effective antidepressant in animal models. It has a high affinity for the 5HT2A and 5HT2C receptors, but does not bind to other serotonin receptor subtypes. 6-Chloro-5-methyl-2,3-dihydro-1H-indole also possesses oral activity and is selective for the 5HT2A receptor subtype. The compound has been cloned and evolutionarily optimized to produce a more potent and selective compound.</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

2-Bromo-5-isopropoxybenzaldehyde is an isopropoxy analog of the natural product suzukol. It has been synthesized by a novel methodology involving oxidative bromination of the phenylacetone. This compound has been used as a model for the synthesis of 2,3,4,5-tetrahydrobenzofuran and can be used as a starting material for the synthesis of other natural products.

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>3-Amino-5-methoxyphenol is a chiral compound with two enantiomers. It has been shown to inhibit tumour growth and to have antitumour properties. 3-Amino-5-methoxyphenol has also been found to be effective against Gram-positive bacteria, such as methicillin resistant Staphylococcus aureus (MRSA). 3-Amino-5-methoxyphenol binds to the active site of bacterial ribosomes and inhibits protein synthesis. This leads to cell death by inhibiting the production of proteins vital for cell division. 3-Amino-5-methoxyphenol can also be used as an antibiotic in humans because it does not affect the metabolism of human serum.</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>