Building Blocks

Versatile small molecule scaffold

3-(4-Fluorobenzenesulfonyl)butanoic acid is a chemical compound that belongs to the class of organic compounds known as sulfones. It is an inhibitor of ion channels and ligands for G-protein coupled receptors. This compound has been shown to inhibit the activity of protein kinases, such as cyclin-dependent kinase 1 (CDK1), which are involved in cell growth and proliferation. 3-(4-Fluorobenzenesulfonyl)butanoic acid also has been shown to be a potent activator of extracellular signal regulated kinase (ERK) 1/2 and JNK mitogen-activated protein kinases (MAPKs), which are important for promoting cell survival.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

4-Iodo-1-butyne is an epoxide that is synthesized by the asymmetric synthesis of 1-butyne. This compound has been shown to have biological effects, such as trimerization, trienylation, and cancer growth inhibition. 4-Iodo-1-butyne also inhibits the production of growth factors, such as epidermal growth factor (EGF) and epidermal growth factor receptor (EGFR). It also has a strong inhibitory effect on cellular proliferation.

Versatile small molecule scaffold

6-Amino-2-(methylsulfanyl)-5-nitroso-3,4-dihydropyrimidin-4-one is a metal complex that has been shown to dehalogenate chloroform and bromotrichloromethane. The enthalpy change for this reaction was measured by calorimetry and found to be -14.8 kJ/mol. This complex also undergoes dehydration with the release of water, which was confirmed by thermal analysis.

Versatile small molecule scaffold

5-(Dimethylamino)pentan-2-one is a volumetric standard that can be used to measure the volume of a liquid. It is prepared by adding equal volumes of heptane and hexadecane in a constant temperature bath, and then adding an equal volume of covid-19, which is a non-electrolyte. The mixture is then stirred until equilibrium is reached. The concentration of 5-(dimethylamino)pentan-2-one in the solution is determined by measuring the volume of the solution from its known density at 25 degrees Celsius. This standard has been shown to have a high accuracy, with an average deviation from the true value of less than 1%.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

1-(4-Methoxyphenyl)cyclopentanecarboxylic acid is a molecule that belongs to the class of primary alcohols. It is an organic compound with a molecular formula of CHOCOCH. The acid-catalyzed reaction of 1-(4-methoxyphenyl)cyclopentanecarboxylic acid with phenol in the presence of concentrated sulfuric acid produces 4-methoxybenzaldehyde. The frequency of this molecule was observed to be 3.2 x 10^5 Hz, which is higher than the frequency expected for amino acids, indicating that it has a lower molecular weight than amino acids.

Versatile small molecule scaffold

4-Ethoxy-2-hydroxybenzaldehyde is a synthetic compound that is structurally similar to natural products such as tuberosum l. and solanum tuberosum. It has been shown to inhibit mitochondrial respiration by binding to the a-ring of the coenzyme Q, which is required for electron transfer in the mitochondria. The presence of dipole groups on the molecule results in a high constant and potent inhibitory activity against mitochondrial respiration.