Building Blocks

2-Hydroxyethane-1-sulfonamide is a potent antiviral agent that inhibits the virus from entering cells by binding to the fatty acid component of the viral envelope. It also has potent antitumor activity and has been shown to be effective against HIV infection. 2-Hydroxyethane-1-sulfonamide binds to mitochondrial matrix proteins, inhibiting fatty acid oxidation and glycogen synthase kinase 3 (GSK3) activation. This inhibition leads to the depletion of cellular energy stores, which eventually results in cell death. 2-Hydroxyethane-1-sulfonamide also inhibits ammonolysis reactions, which converts ammonium into ammonia, a process that is necessary for nitrogen fixation in plants and bacteria.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

1,2-Thiazinane-1,1-dione is a short-chain alkylating agent that has been shown to have neuropathic and inflammatory pain relief. It binds to a number of halides and inhibits their action, including the inhibition of angiotensin I-converting enzyme (ACE), which is an antihypertensive agent. 1,2-Thiazinane-1,1-dione also inhibits the production of epoxides in c1-4 alkyl groups. This drug also has antibacterial properties and can be used as a chemical probe for ligand binding studies.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

N-(2-Hydroxy-2-methylpropyl)acetamide (HMPA) is a molecule inhibitor that inhibits the activity of inflammatory bowel disease (IBD)-associated kinases. HMPA is a member of a family of molecules that are inhibitors of IBD-associated kinases, which may be useful for the treatment of IBD. HMPA has shown in vitro inhibition against two kinases, JNK1 and p38 MAPK, which are both important mediators in the progression of IBD. This drug may be used to inhibit inflammation in the digestive tract by blocking these inflammatory pathways.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

3-Methylphthalic Acid is a chemical that is used in the production of polyvinyl chloride. It is produced by the dioxygenation of phthalic anhydride and methanol, which produces 3-methylphthalic acid as well as 1,1-dichloroethane. The chemical can be used as a surfactant in polyvinyl chloride and styrene production processes. 3-Methylphthalic Acid has been shown to have adverse health effects on laboratory animals, including polyvinyl chloride workers who are exposed to it for prolonged periods of time. The chemical can cause irritation and corrosion to skin and eyes, as well as damage to the liver and kidneys.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

((Cyclopent-3-en-1-yloxy)methyl)benzene (CPMB) is a cyclopentanoid that is found in nature. It has a hydrophilic substituent on the 3rd carbon and a hydroxyl group on the 1st carbon. The substitution at the 3rd carbon is an unresolved stereoisomer. CPMB is also a natural product that can be found in mixtures with other compounds. It can be synthesized using cyclopentadiene and connect to form a ring, or it can be created by reacting oxygen atoms from hydrogen peroxide with benzene. CPMB has been studied for its biological effects such as inducing sleep, or its potential use in cancer treatments.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

4-Amino-N-cyclopentylbenzene-1-sulfonamide (ZL0420) is a potential drug that is being researched for the treatment of inflammation. It inhibits the enzyme bromodomain, which is involved in immune function and cancer cell growth. The molecule has been shown to bind to the bromodomains on human cells, leading to a decrease in cytokine production and inflammatory response. ZL0420 also has low toxicity and high affinity for its target. This drug can be used as an inhibitor for other drugs that are designed for the treatment of inflammation or cancer, such as ZL0454.

The peptide is a research tool that can be used to activate certain antibodies and ion channels. It has also been shown to inhibit protein interactions. The peptide is soluble in DMSO, ethanol, and acetonitrile. It has a molecular weight of 438.4 g/mol and an empirical formula of C14H20N2O3S. The CAS number for the peptide is 436091-57-5. The chemical name of the peptide is ({2-[(5-methylisoxazol-3-yl)amino]-2-oxoethyl}thio)acetic acid.

Versatile small molecule scaffold

Versatile small molecule scaffold

3-(Morpholin-4-yl)pyridin-2-amine is a heterocycle that has been shown to be an efficient, regioselective, and nitrogen-containing aliphatic amine. It is a synlett that can be used as an aliphatic amine in the synthesis of nitrogen-containing compounds. 3-(Morpholin-4-yl)pyridin-2-amine has been shown to have efficient methods for the preparation of carbonyl compounds.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold