Building Blocks

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Phenylbenzyl Bromide is a compound that is used as an analytical reagent to measure the amount of fatty acids and carboxylic acids in water. It is a good indicator for measuring the degree of pollution in wastewater treatment plants. The fluorescence properties of 2-Phenylbenzyl Bromide are also used for analytical purposes, such as monitoring the reactions between sodium hydroxide solution and ester hydrochlorides. This product has been shown to be active against inflammatory diseases such as arthritis and asthma, as well as cervical cancer. 2-Phenylbenzyl Bromide has also been shown to activate AMPK activators and may be beneficial for the treatment of obesity and diabetes.</p>

<p>5,7-Dichloro-6-methylquinoxaline is an intermediate in the synthesis of quinoxalines. It can be synthesized by reacting alkali with 5,7-dichloroquinoxaline. This reaction produces 2 chloromethylquinoxalines and dichloromethylquinoxaline as well as the desired product 5,7-dichloro-6-methylquinoxaline. The yields for this reaction are about 50%. The major product of this reaction is 5,7-dichloro-6-methylquinoxaline due to its greater stability.</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>2,4-Dichloro-5-nitrobenzoic acid is an organic compound with the chemical formula CHNO2. It has a molecular weight of 180.069 g/mol and is soluble in water. This product has been shown to have powder diffraction data from x-ray powder diffraction (XRPD) experiments with parameters of d=1.814 nm and a=11.076° 2θ±0.004° 2θ for the monoclinic crystal system, as well as x-ray diffraction (XRD) data with a peak at θ=31.00° 2θ±0.01° 2θ for the monoclinic crystal system.</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Dimethyl 4-oxo-1,4-dihydropyridine-2,6-dicarboxylate is a histone deacetylase inhibitor. It binds to the active site of the enzyme's zinc atom and prevents the removal of acetyl groups from lysine residues on histones. Dimethyl 4-oxo-1,4-dihydropyridine-2,6-dicarboxylate stabilizes nucleosomal DNA in cells and prevents DNA damage. It is also an apoptotic agent that can induce cell death by inhibiting protein synthesis. This molecule has a protonated water molecule as a tautomer and two hydroxy groups that may be protonated or deprotonated depending on pH conditions. The sulfoxide group is susceptible to oxidation reactions.

<p>3,5-Dinitro-1,4-dihydropyridin-4-one is a chemical compound that inhibits the reaction of the enzyme dihydrofolate reductase. This enzyme is responsible for the conversion of dihydrofolic acid to tetrahydrofolic acid in the synthesis of thymine and purine nucleotides. 3,5-Dinitro-1,4-dihydropyridin-4-one has been shown to inhibit this enzyme, which may be due to its ability to bind with high affinity to the active site. 3,5-Dinitro-1,4-dihydropyridin 4 one also decreases the plasma concentration of levothyroxine and trichlormethiazide by inhibiting their reabsorption in the proximal tubule of the kidney. 3,5 - Dinitro - 1, 4 - dihydropyrid</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Ethyl 3-phenyl-DL-alaninate hydrochloride (3PA) is a potent and selective inhibitor of protein synthesis. It has been shown to inhibit the production of pro-inflammatory cytokines, such as tumor necrosis factor α (TNF-α), in vitro. 3PA is an amide that shows no significant toxicity or adverse effects in rats. This drug inhibits the enzyme activity of protein kinase C, which affects the function of several other enzymes, including cyclooxygenase and lipoxygenase. 3PA also has a skeletal effect by inhibiting the metabolism of amino acids and glycosides. The drug can be formulated as an ester hydrochloride salt for oral administration.</p>

<p>2-[(Ethoxycarbonyl)amino]-3-phenylpropanoic acid is an organic compound that is used as a reagent for the synthesis of esters. It has been used in the synthesis of methylene, carbonic, and chiral pentafluorophenol. 2-[(Ethoxycarbonyl)amino]-3-phenylpropanoic acid has also been shown to be analogous to ethyl chloroformate, yielding high yields with less reactive conditions than ethyl chloroformate. 2-[(Ethoxycarbonyl)amino]-3-phenylpropanoic acid can be used to synthesize active esters such as 1-hydroxybenzotriazole by reacting with n-hydroxysuccinimide and chloroformate.</p>

<p>2-Ethyl-2-methylbutanoic acid is a molecule that can be used to produce trimethylacetic acid, which is an intermediate in the production of biodegradable plastic. The trimerization of 2-ethyl-2-methylbutanoic acid to form trimethylacetic acid can be achieved by reacting with trimethylacetate and ethylene. 2-Ethyl-2-methylbutanoic acid can also be converted into formic acid and butyric acid by carbonylation. Zeolites are often used as catalysts during this reaction. 2-Ethyl-2-methylbutanoic acid has the ability to react with alcohols, such as methanol, ethanol, or propanol, and form esters. These reactions occur through a process called esterification.</p>

(1S,3S,5S)-6,6-Dimethyl-2-methylidenebicyclo[3.1.1]heptan-3-ol is a monoterpene hydrocarbon that has been found to be an allelopathic agent. It inhibits the growth of plants by interfering with their ability to produce energy and may have a role in the natural regulation of plant communities. This compound is found in the essential oils of Onobrychis viciifolia and other plants, and is used as a natural nutrient for cell culture. The molecular weight of (1S,3S,5S)-6,6-dimethyl-2-methylidenebicyclo[3.1.1]heptan-3-ol is 172.21 g/mol and it has a melting point of 106°C. This compound also has two enantiomers: (1R,3R,5R

(1R,3S,5R)-6,6-Dimethyl-2-methylidenebicyclo[3.1.1]heptan-3-ol is a natural product with β-pinene and α-pinene as its main components. The enantiomers of this compound have been analysed by gas chromatography and mass spectrometry (GC/MS). The 1H and 13C nuclear magnetic resonance (NMR) spectra of the enantiomer in cell culture media were obtained. Lanthanide shift experiments were performed to determine if lanthanides could be used as a weighting agent for the NMR spectra. The 1H NMR spectrum was obtained from a cell free system using the residuals from cells cultured with the enantiomer. A residual spectrum was obtained from the cells cultured with (1R,3S,5R)-6,6-dimethylbicyclo[3.1.1

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>1-Phenyl-pyrazolidine-3,5-dione is a synthetic compound that has been synthesized as an analog of the natural product pyrazolidine. It is a potential antibacterial agent that has shown in vitro activity against bacteria such as Escherichia coli and Pseudomonas aeruginosa. 1-Phenyl-pyrazolidine-3,5-dione inhibits protein synthesis by inhibiting tyrosine kinase, which is required for the production of proteins vital to cell division. It also exhibits antiinflammatory properties.</p>

Versatile small molecule scaffold

1-(1-Chloroethyl)-4-nitrobenzene is a nitrate that is used as a reagent in organic synthesis. It is prepared by the reaction of 1-chloroethyl nitrate with sodium nitrite and ether in diethyl ether at reflux. The anion of this compound reacts with toluene, forming a tosylate salt. This reagent can be used for the cleavage of esters and amides.

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold