Building Blocks

<p>Laudanosine is a gamma-aminobutyric acid (GABA) analog that is metabolized by the liver to form laudanosine. Laudanosine has been shown to be a competitive antagonist of benzodiazepine binding sites, including those of atracurium, mivacurium chloride, and diazepam. Laudanosine has also been shown to inhibit cyclic nucleotide phosphodiesterases in vitro, with clinical relevance for its use as an anti-epileptic drug.</p>

H-Lys(Boc)-OH is an ε-amino-protected lysine that plays a pivotal role in solution phase peptide synthesis. Strategically protected at the ε-amino group, it allows controlled peptide assembly, and it serves as intermediate for synthesizing β-peptides. The bulky Boc (tert-butyloxycarbonyl) group shields its epsilon amine (NH2) group, acting as a protective measure to prevent unwanted side reactions.

<p>Versatile small molecule scaffold</p>

<p>2-Methyl-5-nitrobenzaldehyde is a nitro compound that is used in the synthesis of dobutamine. It has been shown to undergo rearrangements, with the formation of 2-methyl-5-nitrophenol. Kinetic studies have shown that chlorine can be substituted for hydrogen at the 2 position, and this substitution leads to an increase in reactivity. 2-methyl-5-nitrobenzaldehyde also reacts with dopamine to form a ketone. The hydroxy group on this molecule is nucleophilic and can attack electrophiles, making it useful as an active site for synthetic reactions. This compound is also pyrophoric, which means it will spontaneously ignite in air and burn until all its fuel is consumed.</p>

<p>6-Maleimidocaproic acid N-hydroxysuccinimide ester (6MCA-NHS) is a fluorescent probe that reacts with the hydroxyl group of fatty acids in human serum and other biological samples. 6MCA-NHS binds to the carboxylic acid group at the end of a fatty acid molecule, forming a covalent bond. This process generates light emission that can be detected by a fluorescence probe to measure changes in pH or other chemical properties within the solution. 6MCA-NHS has been used as a tumor treatment, where laser ablation is used to break up tumor cells and release 6MCA-NHS into the cytoplasm. The drug can then bind to DNA molecules and inhibit protein synthesis, which results in cell death.</p>

<p>Please enquire for more information about 2-Methyl-2H-indazol-5-ylamine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about N-Me-D-Ala-OMe·HCl including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about N-Nitroso ramipril including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

Please enquire for more information about N-​Nitroso hydrochlorothiazide including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

2-Imidazolidone-4-carboxylic acid is a potent inhibitor of matrix metalloproteinases, which are enzymes that break down proteins in the extracellular matrix. 2-Imidazolidone-4-carboxylic acid inhibits the activity of both serine protease and matrix metalloproteinase, two enzymes involved in the inflammation process. 2-Imidazolidone-4-carboxylic acid has been shown to inhibit the transport of amino acids, leading to decreased protein synthesis and cell growth. It also inhibits cancer cells by disrupting their ability to grow new blood vessels and invade other tissues.

Please enquire for more information about RC-3095 trifluoroacetate including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>Versatile small molecule scaffold</p>

<p>2,6-Dimethylphenylacetic acid is a hydrogen phosphate that is soluble in solvents such as acetonitrile. It has been used in the synthesis of lidocaine with high sensitivity and specificity. It can be used to detect phosphoric compounds, which are often present in pharmaceuticals and food supplements. This compound has also been shown to have a solvent effect on the conditions of the reaction, making it a useful additive for optimizing processes. The main impurities of this compound are 2-methylbenzoic acid and benzoic acid.</p>

Versatile small molecule scaffold

2-Methylthiazole-4-carboxaldehyde is an aldehyde that is the product of the condensation of 2,4-dibenzoylacetone and acetone in the presence of diazomethane. It has been used as a precursor to other compounds such as benzoyl chloride, glyoxal, and aldehydes. 2-Methylthiazole-4-carboxaldehyde can be synthesized using acetylation or nitration of thiols or with glyoxal or aldehyde. The reactivity of this compound is high and can be carried out in high yield.

3-(3'-Trifluoromethylphenyl)propanol is a trifluoroacetic acid derivative that is used in acylation reactions to form esters. It can be obtained by the reaction of aluminium chloride, isopropyl alcohol, and phosphine with 3-trifluoromethylaniline. Impurities may include chloride and zirconium. The trifluoromethyl group on this molecule can react with the carbonyl group of an organic acid to form a trifluoroacetate ester.

Valine is a non-essential, branched-chain amino acid that is used for the treatment of bowel disease. Valine is a water-soluble, colorless and odorless crystalline powder that has a sour taste. It can be prepared by reacting valeric acid with ammonia in the presence of an alkali or by hydrolysis of proteins. Valine is also widely distributed in animal tissues, where it participates in the biosynthesis of important biological compounds such as coenzyme A. The optimum concentration to achieve maximum electrochemical impedance spectroscopy (EIS) signal was observed at 20 mM. The EIS signal was found to be dependent on the pH and protein content of the solution matrix. Valine binds to human serum albumin and exhibits strong hydrogen bonding interactions. In addition, valine possesses a signal peptide that helps export it from cells into blood plasma.