Ácidos y reactivos sintéticos

<p>Applications 4-Chloro-3-nitrophenol is degraded by Burkholderia sp. strain SJ98 and utilizes it as sole source of carbon, nitrogen and energy under aerobic conditions. Also it is an intermediate of 8-Hydroxychlorpromazine (H824905), which is a metabolite of chlorpromazine (C424750) which is used as an antiemetic.<br>References Pandey, J., et al.: Appl. Microbiol. Biotechnol., 92, 597-607 (2011); Roth, J., et al.: Comm. Psychopharmacol., 3, 235 (1979); Zhang, Z.: Handbook of Metabolic Pathways of Xenobiotics, 3, 1102 (2014); Anden, N.-E., et al.: Eur. J. Pharmacol., 11, 303 (1970), Curzon, G., et al.: Trends Pharmacol. Sci., 11, 61 (1990)<br></p>

<p>Applications Platinum On Carbon (10 wt. %) is a catalyst used for the hydrogenation of alkenes, alkynes, nitro groups, ketones, aromatics; the hydrogenolysis of cyclopropanes; and catalyzes oxidation of alcohols.<br>References Chauhan, M., et al.: J. Organomet. Chem., 645, 1-13 (2002); Bruno, M.M., et al.: J. Power Sources, 278, 458-463 (2015); Oi, R., et al.: S. Chem. Lett., 7, 1115 (1988); Palmer, C.J., et al.: Tetrahedron Lett., 31, 2857 (1990);<br></p>

<p>Applications Diisopropyl Azodicarboxylate is an azodicarboxylic acid derivative used as a reagent in the production of many organic compounds. Diisopropyl Azodicarboxylate is commonly used as an oxidizer in Mitsunobu reactions and can also serve as a selective deprotectant of N-benzyl groups in the presence of other protecting groups.<br>References Pichika, R. et al.: Nuc. Med. Biol., 38, 1183 (2011); Kroutil, J. et al.: Synthesis, 3, 446 (2004); Hughes, D.L. et al.: Org. React., 42, 335 (1992);<br></p>

<p>Applications Phenylselenyl Bromide is used as a reagent in the synthesis of the antihyperglycemic agent, (+)-Antroquinonol. Phenylselenyl Bromide is also used in the preparation of 9-epi-Artemisinin (A777505); the chiral isomer of Artemisinin (A777500) which is an antimalarial.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sulake, R.S., et al.: J. Org. Chem., 80, 6044 (2015); Orabi, K.Y. et al.: Phytochem., 51, 257 (1999); Jefford, C.W. et al.: Helv. Chim. Acta, 83, 1239 (2000); Klayman, D.L., et al.: Science, 228, 1049 (1985)<br></p>

<p>Applications Benzeneruthenium(II) Chloride Dimer is a catalyst for SNAr reactions of fluoroarenes and cyclic amines, a precatalyst for the hydrogenation of β-keto esters and a precursor for the preparation of other ruthenium catalysts.<br></p>

<p>Applications Bis(dibenzylideneacetone)palladium is a compound used as a component of a potentiometric membrane sensor to selectively determine the presence of thiocyanate in the urine of cigarette smokers. Bis(dibenzylideneacetone)palladium is also used as one of the homogeneous catalysts in the synthesis of Tricyclopentadiene from Dicyclopentadiene (D439350).<br>References Hassan, S., et al.: Electroanalysis, 18, 2070 (2006); Woo, J., et al.: Appl. Organomet. Chem., 28, 151 (2014)<br></p>

<p>Applications (R)-(+)-Propylene Oxide is used as a reagent in the synthesis of Brivanib Alaninate (B677640); a novel pyrrolotriazine VEGFR/FGFR inhibitor.<br> E3<br>References Lobben, P.C., et al.: Org. Process Res. Dev., no vol., no pp. (2014, ahead of print)<br></p>

<p>Applications Platinum chloride is a useful inorganic reagent which has been used in the preparation and characterization of Ru-Pt core-shell nanoparticles.<br>References Jin, S.; et al.: Yingyong Huaxue 35, 239 (2018).<br></p>

<p>Applications Sodium Phosphate Dibasic is used as an in conjunction with trisodium phosphate in foods and water treatment. In foods, it is used to adjust pH. In water treatment, It retards calcium scale formation. It is also found in some detergents and cleaning agents. Sodium Phosphate Dibasic is used as a saline laxative to treat constipation or to clean the bowel before a colonoscopy.<br>References Tsioulpas, A., et al.: Food Chem., 122, 1027 (2010); Schrödter, K., et al.: Ullmann’s Encyclopedia of Industrial Chemistry (2008); Hansen, C., et al.: Am. J. Obstet. Gynecol., 196, 311 (2007)<br></p>

<p>Applications Dichlorophenylphosphine (cas# 644-97-3) is a useful research chemical.<br> E0<br></p>

<p>Applications Dichloroacetyl Chloride is a reagent used in the synthesis of substituted benzothiazoles exhibiting antitumor and anticancer activity.<br>References Chua, M. et al.: J. Med. Chem., 42, 381 (1999);<br></p>

<p>Applications Trimethyltin Hydroxide is a reagent used in the synthesis of modified thymines used as inhibitors of RNase A. Also used in the preparation of Ketoheterocycle inhibitors of fatty acid amide inhibitors,<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Datta, D. et al.: Bioorg. Med. Chem., 21, 4634 (2013); Ezzili, C. et al.: J. Med. Chem., 54, 2805 (2011);<br></p>

<p>Applications Tetrabutylphosphonium Hydroxide is a phase transfer catalyst for the etherification of thiosalicylic acid and analogs. Tetrabutylphosphonium Hydroxide is a pretreatment for rice husks that enhances enzymic and acid hydrolysis yields. Tetrabutylphosphonium Hydroxide is used in the synthesis of tetrabutylphosphonium carboxylate as a recyclable and highly selective catalysts for alcoholysis reaction of propylene oxide.<br>References Lau, B. B. Y., et al.: Bioresour.Technol., 197, 252 (2015); Lei, Y., et al.: Huaxue Shijie, 56, 748 (2015); Tao, D., et al.: Ind. Eng. Chem. Res., 52, 17111 (2013)<br></p>

<p>Applications 5-Amino-3-methylisothiazole Hydrochloride (cas# 52547-00-9) is a compound useful in organic synthesis.<br></p>

<p>Applications can be used in the generation of carbenes, the amination of sulfenamides, and the preparation of lanthanide complexes.<br>References Hasan T.m et al.: Journal of the Chemical Society. Perkin Transactions 1 , 1923-1923, (1992); S C Bock Journal of the American Chemical Society 116, 7637-7637, (1994)<br></p>

<p>Applications Thioisonicotinamide is an impurity of Ethionamide (E890420) with tuberculostatic activity.<br>References Pappalardo, G. et al.: Farm. Ediz. Sco., 22, 808 (1967); Waisser, K. et al.: Cesk.-Slov. Farm., 33, 99 (1984); Devani, M. B. et al.: J. Pharmac. Sci., 43, 1471 (1974);<br></p>

<p>Applications Acetylacetonatobis(ethylene)rhodium(I) is a useful research chemical, a catalyst for the preparation and optical resolution of (tetramethyl)spirobiindane-diol and other useful research chemicals.<br>References Lee, A., et al.: J. Org. Chem., 81, 3520 (2016); Zhou, Q., et al.: Synthesis (2018); Jung, H., et al.: Adv. Synth. Catal., 359, 3160 (2017)<br></p>

<p>Applications 3-Bromo-N,N,N-trimethylpropan-1-aminium Bromide is a compound used to prepare novel hydrophilic-hydrophobic block copolymer based on cardo poly(arylene ether sulfone)s with bis-quaternary ammonium moieties for anion exchange membranes.<br>References Dong, X., et al.: J. Membr. Sci., 518, 31-39 (2016);<br></p>

<p>Applications Lithium bromide is used as an inexpensive catalyst for the opening of epoxide rings by amines at room temperature. Lithium bromide is also used in conjunction with water to create a refrigerant-absorbent solution for use in refrigeration systems.<br>References Arun, M., et al.: Appl. Therm. Eng., 21, 1273 (2001); Chakraborti, A., et al.: Eur. J. Org. Chem., 17, 3597 (2004)<br></p>

<p>Applications Cyclohexanecarbonyl Chloride is used to prepare 1,2,3-triazoles as inhibitors of human immunodeficiency virus type 1 protease. It was also used to synthesize benzothiazole as potent antitumor agents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Whiting, M., et al.: J. Med. Chem., 49, 7697 (2006); Yoshida, M., et al.: Bioorg. Med. Chem. Lett., 15, 3328 (2005)<br></p>

<p>Applications Tetraethylammonium Tetrafluoroborate is used in the preparation of some organic salts of fluoboric acids.<br>References Wilke-D., et al.: Ber. Dtsch Chem. Ges.; 60B, 115 (1927)<br></p>

<p>Applications (4-Nitrophenyl)acetic Acid used in the synthesis of 5,7-dimethyl-2-aryl-3H-pyrrolizin-3-ones which may act as angiogenesis inhibitors. Also used in the one step construction of amino-substituted squaraine dye.<br>References Kirk, N., et al.: Bioorg. Med. Chem. Lett., 26, 1813 (2016); Ying, H., et al.: Dyes Pigments, 131, 264 (2016);<br></p>

<p>Applications A structural homologue of the natural polyamine spermidine with antitumor activity that may make it useful as a antineoplastic agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Prakash, N. et al.: Anticancer Res., 8, 563 (1988); Sunkara, P.S. et al.: Adv. Exp. Med. Biol., 250, 707 (1988); Porter, C.W. et al.: Cancer. Res., 42, 4072 (1982);<br></p>

<p>Applications Potassium Thioacetate is the potassium salt of Thioacetic Acid, a commonly used reagent in organic synthesis for the introduction of thiol groups in molecules.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chapman, J.H. et al.: J. Chem. Soc., 579 (1950);<br></p>

<p>Applications Di-O-acetyl-D-tartaric Anhydride (cas# 70728-23-3) is a compound useful in organic synthesis.<br></p>

<p>Applications A chiral derivative of Camphor.<br>References Peng, R., et al.: Biochem. Pharmacol., 35, 1391 (1986), Tanaka, E., et al.: Biochem. Pharmacol., 41, 472 (1991),<br></p>

<p>Applications 4-Fluoro-3-nitroaniline (cas# 364-76-1) is a useful research chemical.<br></p>

<p>Applications Manganese Chloride Tetrahydrate is an inorganic chemical reagent used in oxidation studies and reactions.<br>References Huynh, M. et al.: J. Am. Chem. Soc., 136, 6002 (2014); Gupta, Y. et al.: Res. J. Chem. Env., 16, 48 (2012);<br></p>

<p>Stability Moisture Sensitive<br>Applications Tin (II) Chloride (in dilute solutions of HCl) is used as a reductant, and is utilized to prepare surfaces for electroless plating. Tin (II) Chloride is also used as a mordant in the textile industry because of its ability to form an insoluble precipitate with the dye, ultimately fixing it into the fiber. Tin (II) Chloride is also a reagent that is known to produce DNA damage in Chinese hamster ovary cells.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cohen, R., et al.: J. Electrochem. Soc., 119, 433 (1972); Jothi, D.: Autex. Res. J., 8, 49 (2008); McLean, J., et al.: Mutat. Res. Lett., 119, 195 (1983);<br></p>

<p>Applications Dimethyl (2-Oxoheptyl)phosphonate is a useful synthetic intermediate, and is used as a reagent to synthesize Caffeic acid (C080000) derivatives, which function as 5-lipoxygenase, 12-lipoxygenase, and prostaglandin synthase inhibitors.<br>References Sugiura, M., et al.: Chem. Pharm. Bull., 37, 1039 (1989)<br></p>

<p>Applications 1,8-Dibromooctane is used as a reagent in the synthesis of novel 7-aminoalkyl-substituted flavonoid derivatives as potential cholinesterase inhibitors.<br>References Luo, W., et al.: Bioorg. Med. Chem., 24, 672 (2016)<br></p>

<p>Applications Tetrakis(acetonitrile)copper(I) Hexafluorophosphate (cas# 64443-05-6) is a useful research chemical.<br></p>

<p>Applications (S)-1-Aminoindane is the S-enantiomer of 1-Aminoindane; the metabolite of the monoamine oxidase-B inhibitor Rasagiline (R126000).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Glezer, S. et al.: Eur. J. Pharmacol., 472, 173 (2003);<br></p>

<p>Applications 1,4-Cyclohexanedione Monoethylene Acetal is used in the preparation of series of potent analgesic compounds. 1,4-Cyclohexanedione Monoethylene Acetal is also used as a building block in the synthesis of tritium labelled probes for the autoradiography study of the dopamine reuptake complex.<br>References Linders, J. et al.: J. Lab. Comp. Radiopharm., 31, 671 (1992); Lednicer, D. et al.: J. Med. Chem., 22, 1157 (1979);<br></p>

<p>Applications tert-ButylBrettPhos is a ligand commonly found on palladium catalysts used in the regioselective 2-amination of polychloropyrimidines.<br>References Smith, S.M., Buchwald, S.L., Org. Lett., 9, 2180-2183 (2016)<br></p>

<p>Applications 2-(4-Chlorophenyl)ethylamine has been used as a reactant in the preparation of isoalloxazine derivatives as cholinesterase inhibitors with a potential use in Alzheimer therapy.<br>References Kanhed, A.M., et. al.: Bioorg. Chem., 61, 7 (2015)<br></p>

<p>Applications Samarium, can be used in the reduction of arylsulfonyl chlorides and arylsulfinates in combination of titanium(IV) chloride to make diaryl disulfides.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Janjetovic M. et. al.: Journal of physics. Condensed matter : an Institute of Physics journal, 25(2), undefined (2012-12-5)<br></p>

<p>Stability Light Sensitive<br>Applications Itaconic acid is an unsaturated dicarbonic acid that is used as a comonomer in resins, synthetic fibers, and rubbers. Itaconic acid is naturally biosynthesized by Aspergillus terreus, but is also synthesized in a macroscale basis from sugars.<br>References Okabe, M., et al.: Appl. Microbiol. Biot., 84, 597 (2009); Wilke, T., et al.: Appl. Microbiol. Biot., 56, 289 (2001)<br></p>

<p>Applications 2-CHLOROSTYRENE (cas# 2039-87-4) is a useful research chemical.<br></p>

<p>Applications Allenylboronic acid pinacol ester<br></p>

<p>Applications 2,3-O-Isopropylidene-L-threitol is an intermediate in the synthesis of versicolactone compounds.<br>References Wang, L., et al.: Tetrahedron. Lett., 54, 6729 (2013);<br></p>

<p>Applications Sodium Hydrosulfide Hydrate is a stable hydrogen sulfide (H2S) donor and oxidant in the formation of benzothiazoles. It is also used as a reagent in the synthesis of imidazo[1,2-b]thiazole derivatives as novel SIRT1 activators.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Meng, J., et al.: Int. J. Impot. Res., 25, 86 (2013); Park, N., et al.: Eur. J. Org. Chem., 2012, 1984 (2012); Vu, C.B., et al.: J. Med. Chem., 52, 1275 (2009)<br></p>

<p>Applications Sodium Bismuthate, is an inorganic compound, which is a strong oxidiser. Sodium Bismuthate converts almost any manganese compound to permanganate, which is easily assayed spectrophotometrically.<br>References Kitchin, J., et al.: Encyclopedia of Reagents for Organic (2001); Seiburger, Ch., et al.: Revista de la Asociacion Argentina de los Quimicos y Tecnicos de la Industria del, 8, 73 (1967);<br></p>

<p>Applications Diphenylphosphine oxide (cas# 4559-70-0) is a useful research chemical.<br></p>

<p>Applications 2-Chloropropanoic acid is a component of the oil-based lubricoolant SP-4. It is also a neurotoxicant.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ermolaeva, N. V., et al.: Ekologiya Urbanizirovannykh Territorii, 2, 39-43 (2015); Pritt, Michael L., et al.: Toxicological Sci., 141(2), 398-408 (2014)<br></p>

<p>Applications (S)-(-)-1-(1-Naphthyl)ethylamine is used in the asymmetric synthesis of α-cyanocarboxylates. Also used in the synthesis of chiral imadazolin-2-ylidene ligands used in organometallic catalysis. Chiral/Asymmetric synthesis.<br>References Herrmann, W. et al.: Organometal., 16, 2472 (1997); Martin, F. et al.: 121, 5467 (1999); Sawamura, M. et al.: J. Am. Chem. Soc., 114, 8295 (1992);<br></p>

<p>Applications Chloro(triethylphosphine)gold is an analogue of auranofin. Auranofin and its analogs show antimicrobial activity against multidrug-resistant pathogens<br>References Tizian M. et al.: Chem. Med. Chem. 13(22), 2448-2454 (2018)<br></p>

<p>Applications LITHIUM FLUORIDE (cas# 7789-24-4) is a useful research chemical.<br></p>

<p>Stability Hygroscopic<br>Applications 3-Phenylpropylamine is an compound used for the synthesis of various pharmaceuticals.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kamochi, Y., et al.: Tetrahedron. Lett., 32, 3511 (1991);<br></p>

<p>Applications Diisopropyl Malonate is a disinfection byproduct of Isoprothiolane (I874300); a dithiolane pesticide commonly used in agriculture as a fungicide to control planthoppers and blast disease in rice plants.<br>References Chin, K.M.: Malay. Agric. J., 50, 221 (1975); Ikeda, Y. et al.: Biosci. Biotech. Biochem., 57, 288 (1993); Nakamura, H.: Rev. Plant Prot. Res., 10, 1 (1977); Reddy, A.P.K. et al.: Pesticide, 22, 21 (1988); Jinno, H., et al.: Arch. Toxicol., 71, 550 (1997)<br></p>

<p>Applications 4-Amino-1-(diethylamino)pentane was used as a reagent in the synthesis of chromone-2-carboxamide derivatives which displayed cytotoxic activity against specific cancer cell lines.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bousejra-ElGarah, F., et al.: Med. Chem. Res., 1054, pages ahead of print (2016);<br></p>

<p>Applications 1,5-Cyclooctadiene(pyridine)(tricyclohexylphosphine)iridium(I) Hexafluorophosphate is a catalyst that is used in the synthesis of 4α,5-Dihydro Simvastatin (D450010). 4α,5-Dihydro Simvastatin is an impurity in the synthesis of Simvastatin (S485000), a synthetic derivative of a fermentation product of Aspergillus terreus. A competitive inhibitor of HMG-CoA reductase. A synthetic analog of Lovastatin. Antilipemic. Simvastatin, the drug, is sold under the trade name Zocor.<br>References Hoffman, W.F., et al.: J. Med. Chem., 29, 849 (1986), Mol, M.J., et al.: Lancet, 2, 936 (1986),<br></p>

<p>Applications Used in the preparation of Camptothecin derivatives, for their therapeutic use as antitumor agents.<br>References Wani, M.C., et al.: J. Med. Chem., 29, 2358 (1986), Miller, K.D., et al.: Invest. New Drugs, 22, 69 (2004), Punt, C.J.A., et al.: Eur. J. Cancer, 40, 1332 (2004), Wang, J.-Q., et al.: Bioorg. Med. Chem., 13, 549 (2005)<br></p>

<p>Applications Sodium sulphate decahydrate (CAS# 7727-73-3) is a useful research chemical compound.<br></p>

<p>Applications Acetylenedicarboxylic Acid is used as an electrolyte in the fabrication of anodic nanoporous alumina. It is also used as a reagent in the synthesis of several organic compounds including that of derivatives of metronodazole (antibiotic and antiprotozoal medication) which display increased antimicrobial and antiparasitic properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kikuchi, T., et al.: Electrochem. Lett., 3, C25 (2014); Al-Masoudi, N., et al.: Monatsh. Chem., 147, 383 (2016);<br></p>

<p>Applications Tetraethylammonium P-Toluenesulfonate (cas# 733-44-8) is a useful research chemical.<br></p>

<p>Applications (S)-(-)-Glycidol is a cyclic AB 2-type monomer that can be polymerized in a ring-opening multibranching polymerization. S)-(-)-Glycidol is also used as a starting reagent to synthesize non-peptidic HIV protease inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chiummiento, L., et al.: Tetrahedron, 65, 5984 (2009); Tokar, R., et al.: Macromolecules, 27, 320 (1994)<br></p>

<p>Applications Benzyltributylammonium Bromide (cas# 25316-59-0) is a useful research chemical.<br></p>

<p>Applications Tetrakis(acetonitrile)palladium Bis(tetrafluoroborate) is used to prepare an α-Diimine-transition metal complex, which is used as a catalyst for polymerization of olefins. It is also a catalyst used in cross coupling reaction for C-C, C-O, and C-N bond formation.<br>References Feldman, J., et al.: Organometallics, 16, 1514 (1997); Johnson, L., et al.: PCT Int. Appl., WO 9623010 A2 19960801 (1996); Poppenbery, J., et al.: Surface Sci., 2011; Pijnenburg, N., et al.: Dalton Transactions, 40, 8896 (2011); Kilpin, K., et al.: Inorg. Chem., 50, 6334 (2011)<br></p>

<p>Applications Zinc Bromide is used as a catalyst in the synthesis of tetrazoles which exhibit antibacterial activity in vitro. Zinc Bromide is also a zinc salt that is added as a nutritional or functional ingredient in food and oral care products.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cui, J., et al.: Xiandai Shengwuyixue Jinzhan, 12, 3478 (2012); Keast, R.S.J.: J. Food Sci., 68, 1871 (2003)<br></p>

<p>Applications Vanadium(IV) Oxide Acetylacetonate is used as a catalyst in organic chemistry and is also an intermediate in synthetic reactions, such as the synthesis of novel oxovanadium complexes that display antitumor activity.<br>References Rui, W. et al.: Polyhedron, 117, 803 (2016); Tahmasebi, V. et al.: J. Mol. Struct., 1123, 367 (2016);<br></p>

<p>Applications Nickel(II) Acetate Tetrahydrate is a reactant in the synthesis of metalloprophyrazines as active components of membranes of anion-selective electrodes.<br>References Shvedene, N.V., et. al.: J. Anal. Chem., 70, 72 (2015)<br></p>

<p>Applications [(η-6-Cymene)[(S,S)-1,2-diphenyl-N-tosyl-1,2-ethanediaminato]ruthenium] chloride] is an catalyst used for enantioselective hydrogenation of quinolines, N-Alky Ketimines and antitumor, antiproliferative derivatives of natural products isolated from bacteria.<br>References Bligh, C.M., et al.: J. Org. Chem., 79, 328 (2014); Brownell, K.R., et la.: J. Am. Chem. Soc., 135, 14299 (2013);<br></p>

<p>Applications 4-Benzoylbenzoic acid is a reagent that is used in the synthesis of BzATP Triethylammonium Salt, which is a selective P2X purinergic agonist. It is more potent than ATP at homodimeric P2X7 receptors.<br>References Cole, D., Yount, R.: J. Biol. Chem., 265, 22537 (1990); Atarashi, K., et al.: Nature, 455, 808 (2008)<br></p>

<p>Applications Lithium Iodide Hydrate is used in the dehydration of alkali metal iodides in vacuum and in the dehydration of lithium iodide hydrate crystals.<br>References Sofronov, D. S., et al.: Functional Materials, 12, 559 (2005), Demidov, A. I., et al.: Zhurnal Prikladnoi Khimii, 71, 1249 (1998)<br></p>

<p>Stability Moisture Sensitive<br>Applications 4-Methoxybenzyl Chloride is used as a reagent in the preparation of pyridone-conjugated monobactam antibiotics with gram-negative activity from Pseudomonas aeruginosa, Klebsiella pneumoniae, and Escherichia coli.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Brown, M F., et al.: J. Med. Chem., 5541 (2013); Cooper, M., et al.: Nature, 32, 472 (2011)<br></p>

<p>Applications Methyl cyanoformate is a reagent that is used in the preparation of XEN907, which is a spiro-oxindole blocker of Nav1.7 for the treatment of pain.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chowdhury, S., et al.: Bioorg. Med. Chem. Lett., 21, 3676 (2011);<br></p>

<p>Applications POTASSIUM HEXAFLUOROPHOSPHATE (cas# 17084-13-8) is a useful research chemical.<br></p>

<p>Applications 2-Iodoanisole is a useful synthetic intermediate. It can be used in the synthesis of piperidinyl diaminopyrimidines as cyclin-dependent kinase inhibitors with antitumor activity and polysubstituted benzofuran derivatives as novel inhibitors of parasitic growth.<br>References Chu, X., et al.: J. Med. Chem., 49, 6549 (2006); Thevenin, M., et al.: Bioorg. Med. Chem., 21, 4885 (2013)<br></p>

<p>Applications ert-Butyl nitrite is an intermediate used for diazotization and nitros­ation of alcohols, thiols, amines and cycloalkanes. It is also used to prepare aryl azides from aryl amines.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Liu, Y.: Synlett., 8, 1184 (2011); Barral, K., et al.: Org. Lett., 9, 1809 (2007)<br></p>

<p>Stability Very Moisture sensitive<br>Applications (R)-(+)-α-Methylbenzyl isocyanate is used in the synthesis of non-steroidal mineralocorticoid receptor antagonists. Also used in the synthesis of antiviral and anti-HIV agents such as DPC 961.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Yang, C. et al.: ACS Med. Chem. Lett., 6, 461 (2015); Andrushko, V. (2013). Stereoselective Synthesis of Drugs and Natural Products. Hoboken, NJ: John WIley &amp; Sons.<br></p>

<p>Stability Moisture Sensitive<br>Applications 4-Nitrobenzyl Chloroformate is used in the preparation of prodrugs of cytotoxic acridines used in conjunction with enzyme prodrugs which counter carcinoma cells.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Asche, C. et al.: Bioorg. Med. Chem. Lett., 16, 1990 (2006); Hay, M. et al.: J. Med. Chem., 46, 2546 (2003);<br></p>