Alcoholes

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<p>(S)-(-)-3-Chloro-1-phenyl-1-propanol is an efficient method for the synthesis of chiral propiophenone. It is synthesized by reacting a mixture of borane and tetrahydrofuran with (S)-(-)-3-chloro-1-phenylpropanol. This reaction produces the desired compound in good yield and high diastereoselectivity. The synthesis of this compound has been shown to be useful for the production of antidepressant drugs, such as κ-opioid receptor ligands, which are used to treat depression, anxiety, and chronic pain.</p>

<p>2-(5-Bromo-2-pyridylazo)-5-(diethylamino)phenol is a chemical that is used for the detection of hydrochloric acid in water vapor. It reacts with zirconium oxide, which generates a red fluorescing complex. The reaction can be detected by using a fluorescence spectrometer with a test sample. 2-(5-Bromo-2-pyridylazo)-5-(diethylamino)phenol is also used to detect the presence of nitrogen atoms and sodium citrate in samples by reacting with them. This chemical reacts with an acid complex to form stable complexes. The analytical method is based on measuring the redox potential of this reaction. The flow system of this technique allows for dehydration of dehydroascorbic acid (DHA).</p>

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<p>1-O-Octadecyl-sn-glycerol (1ODG) is a dietary lipid that is absorbed by the gastrointestinal tract and transported to the liver. It is used in cell culture as a substitute for lipids that are not available or cannot be used for experiments. 1ODG is also found in human lung and colon tissues, where it may act as a growth factor. 1ODG has been shown to inhibit herpes simplex virus type I (HSV-1) replication in cultured cells by increasing intracellular calcium levels and inhibiting viral DNA synthesis. It can also increase fatty acid synthesis and induce cellular proliferation of tissue culture cells, such as lung fibroblasts.</p>

<p>Xylenol orange is a dye used as a pH indicator. It is typically present as the monosodium salt of xylenol and has an optimum concentration of 0.2-0.5 mg/L. Xylenol orange is highly soluble in water and can be used in aqueous solutions, but it should not be used with strong acids or alkalis, as they will cause the dye to precipitate out of solution. Xylenol orange reacts with acidic substances and changes colour from orange to yellow at pH 7.0 or higher. The mechanism behind this reaction involves the deprotonation of xylenol by acid, followed by protonation of the conjugate base, which then undergoes electrophilic substitution by hydroxide ions (OH−). This reaction is shown below: XO+H+→XO−+H+ XO−+OH−→HO−+X The Langmuir</p>

<p>Bisphenol A glycerolate dimethacrylate is a synthetic polymer that has been used in various applications, including dental sealants and composites. It is a white or yellowish viscous liquid that is soluble in water and alcohol. Bisphenol A glycerolate dimethacrylate is used as a sealant due to its high viscosity. The molecular weight of this compound ranges from 2000 to 6000 Da. It also has an epoxy group that can form hydrogen bonds with other molecules. The major application for bisphenol A glycerolate dimethacrylate is in the dental industry as it provides an excellent sealant due to its high viscosity. This material is also used in composites due to its ability to form hydrogen bonding interactions with the polymer matrix. Bisphenol A glycerolate dimethacrylate is also known for its hemolytic activity and sugar transport properties, which are important for lactic acid</p>

<p>2-Dimethylaminoethanol (+)-bitartrate salt is a potent, reversible inhibitor of protein synthesis that binds reversibly to the 50S ribosomal subunit. It is used in regulatory toxicology and clinical pathology as a positive control for the study of chronic toxicity and long-term effects. 2-Dimethylaminoethanol (+)-bitartrate salt has shown no treatment effect on ovary weight or estrous cycle length in female Sprague-Dawley rats after chronic exposure and long-term exposure at doses up to 1,000 mg/kg/day. This drug has also shown no effect on rat fertility or reproductive performance, indicating it does not cause reproductive toxicity.</p>

<p>Sodium 2,2,2-trifluoroethanolate is a fluorinated alcohol. It is used as an animal health drug and has been shown to have a significant inhibitory effect on the growth of bacteria. The reaction intermediate for this compound is trifluoroacetic acid, which can be formed from sodium and hydrogen fluoride in the presence of ethylene glycol. This molecule also reacts with nitrosyl chloride to form a nitrogen-containing product. Sodium 2,2,2-trifluoroethanolate has been shown to be active against both Gram-positive and Gram-negative bacteria. The FTIR spectra for this compound shows that it has two sets of absorption bands at 3,200 cm−1 (due to C–H stretching) and 3,000 cm−1 (due to C=C stretching).</p>

<p>3-Bromo-4-fluorophenol is a synthetic, water soluble, and stable compound with a variety of applications. It yields white crystals that are soluble in water, acetone, ethanol, ether, benzene, chloroform, and carbon tetrachloride. 3-Bromo-4-fluorophenol has been shown to have a number of structural modifications that may be advantageous for therapeutic purposes. The most prominent modification is the methylation of the phenolic hydroxyl group (functionalisation). This modification prevents the drug from reacting with nucleophilic sites on proteins and other biological molecules. 3-Bromo-4-fluorophenol interacts with methyltransferase enzymes in cancer cells to inhibit their activity. These methyltransferase enzymes are involved in cellular proliferation and proliferation signalling pathways that may lead to cancer cell death.</p>

<p>2,2,4-Trimethyl-1,2-dihydroquinoline is a chemical compound with the formula C8H10N2. It is a white solid that is insoluble in water but soluble in nonpolar solvents such as benzene, toluene and hexane. 2,2,4-Trimethyl-1,2-dihydroquinoline has been shown to induce liver lesions in rats at doses of 1.25 g/kg/day. It also reacts with hydrogen fluoride to form calcium stearate. This compound is also used as a precursor for the synthesis of diazonium salts and has been shown to be carcinogenic in animal studies.</p>

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<p>(S)-1-Phenyl-2-propanol is a chiral, enantiopure alcohol that is used as a substrate for the preparation of various drugs. It can be prepared by the reduction of (R)-1-phenyl-2-propanol with sodium borohydride. To obtain the desired product, high substrate concentrations are required. Molecular modeling and bioreactor studies have shown that this process can also be carried out in cells. Subtilis sps. were found to be suitable for this process due to their ability to synthesize (S)-1-phenyl-2-propanol from 6-phosphate and l-tert-leucine in a stepwise manner. The use of subtilis sps. may reduce the cost and time needed for production of (S)-1-phenyl-2-propanol because it does not require expensive starting materials or purification steps.END&gt;&gt;</p>

<p>Dodecylbenzenesulfonic acid is a sulfonic acid that is used in the production of polyaniline. It is also used as an organic reagent that can be applied in organic synthesis, including polymerization and electrochemical studies. Dodecylbenzenesulfonic acid has been shown to react with sodium salts to form dodecyl benzene, which can be observed by synchronous fluorescence spectroscopy. This chemical has a phase transition temperature of -9°C and a boiling point of 176°C. Dodecylbenzenesulfonic acid is soluble in water vapor, but insoluble in ethanol or acetone.</p>

<p>Dimethyl benzyl carbinol acetate is a polymer that forms a film on the skin and prevents water loss. It has been shown to have enzyme-inhibiting properties, which may be due to its ability to prevent geranyl production. Dimethyl benzyl carbinol acetate has also been used as a sealant in microcapsules, which are then broken down by enzymes in order to release the contents of the capsule. Dimethyl benzyl carbinol acetate can also be used as an antimicrobial agent, where it inhibits bacterial cell growth by interfering with fatty acid synthesis.</p>

<p>4-Bromo-3,5-dimethylbenzyl alcohol is a potent anticancer agent that is synthesized from bromoarenes. It has been shown to be effective against cancer cells in the presence of activated carbon, aluminum chloride, and organotellurium. 4-Bromo-3,5-dimethylbenzyl alcohol reacts with peptide hormones and other hormones at the cellular level by inhibiting DNA synthesis. This inhibition prevents the production of proteins that are vital for cell division. The reaction rate is rapid in solvents such as acetonitrile.&gt;&gt;END&gt;&gt;</p>

<p>DL-Phenylalaninol is a chemical compound with the molecular formula CHNO. It is a white to pale yellow solid that is soluble in water and methanol, but not in diethyl ether. DL-Phenylalaninol has been synthesized by reacting cycloleucine with l-phenylalaninol. The reaction solution was heated at a temperature of 140°C for six hours, which yielded DL-Phenylalaninol as a hydroxy methyl compound. The synthesis of DL-Phenylalaninol was achieved through an asymmetric synthesis with sodium dodecyl sulfate surfactant. A detection sensitivity of 1 ppm and an enhancement at 260 nm were observed when analyzing the product by high performance liquid chromatography (HPLC).</p>

<p>Ethynylestradiol is a synthetic estrogen that is used in hormone replacement therapy. It belongs to the group of estrogens and has been shown to be a potent inhibitor of ovarian activity. Ethinyl estradiol is metabolized through catechol-O-methyltransferase (COMT) and sulfotransferases, which leads to an increased rate constant for its clearance from plasma. The drug also has interactions with other drugs, such as protease inhibitors, which may lead to disease activity or toxicity in the liver. Ethynylestradiol binds specifically to bcl-2 protein, which may be related to its anti-inflammatory properties.</p>

<p>1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine (DLPE) is a lipid molecule that can induce phase transition in aqueous solutions. DLPE is an active ingredient in nonsteroidal anti-inflammatory drugs and has been shown to inhibit the activity of enzymes such as cyclooxygenase and lipoxygenase. DLPE also inhibits the growth of infectious organisms such as Escherichia coli and HIV by inhibiting receptor activity. DLPE binds to receptors on the surface of cells, which prevents these cells from releasing inflammatory cytokines.</p>

<p>Cloprostenol sodium is a prostaglandin analogue that is used in veterinary medicine. It is administered intravenously to induce ovulation, improve estrus and fertility, or control luteal function in cows. Cloprostenol sodium has been shown to have a positive effect on the ovulatory process by stimulating the release of endogenous progesterone and estradiol benzoate from the follicle cells. This drug also increases luteal activity by increasing the production of progesterone and inhibiting its metabolism. Cloprostenol sodium has been shown to be effective in inducing ovulation in pregnant women who do not respond to clomiphene citrate (CC) alone. Cloprostenol sodium can also be used for induction of labour in pregnant women with an uncomplicated pregnancy at term, where it is given intravenously or intramuscularly, but intravaginally or orally are not recommended.</p>

<p>4-Fluoro-2-methoxyphenol is a fluorinating agent that is used in the manufacture of pharmaceuticals, plastics and pesticides. It has been shown to induce apoptosis in cultured cells by upregulating reactive oxygen species (ROS) and increasing mitochondrial membrane permeability, as well as inhibiting cellular physiology. 4-Fluoro-2-methoxyphenol also inhibits the production of ATP and may be toxic to cells by interfering with dinucleotide phosphate.</p>

<p>2,4-Dibromobenzyl alcohol is a selective inhibitor of sglt2, which is an enzyme that inactivates the incretin hormones glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). It has been shown to have a strong inhibitory effect on the activity of sglt2 in vitro. This inhibition leads to increased levels of GLP-1 and GIP, which may help improve glycemic control. 2,4-Dibromobenzyl alcohol has been shown to reduce blood glucose levels in diabetic mice to the same degree as tofogliflozin, which is marketed for diabetes treatment.</p>

<p>Calcipotriol is a synthetic vitamin D3 analog that has been shown to be effective in the treatment of bone cancer. It has a film-forming property and is used in pharmaceutical preparations as well as for wastewater treatment. Calcipotriol monohydrate is made by reacting calcipotriol with hydrochloric acid, which produces an ester bond between the hydroxyl group and the carboxylic acid group. The reaction also produces water, methanol, and methyl ethyl ether. Studies have shown that calcipotriol monohydrate has a chemical stability of over 30 days at room temperature, indicating it can be stored for long periods without degradation.</p>

<p>3-Piperidin-1-ylpropan-1-ol is a substance that is structurally related to biperiden and has affinity for the H3 receptor. It has been shown to have a high affinity for the H3 receptor, which is found in high concentration in the rat brain. 3-Piperidin-1-ylpropan-1-ol has been shown to have antagonistic activity against neuropathic pain in rats, by inhibiting the release of norepinephrine from nerve endings. This substance also has antihistaminic properties, which may be due to its ability to inhibit histamine release. 3-Piperidin-1-ylpropan-1-ol is an enantiomer of piperidine, with a slightly higher affinity for the H3 receptor than its mirror image. The racemic mixture isomeric form (i.e., both enantiomers) inhibits the H3 receptor with an equal potency,</p>

<p>2-(3,4-Dichlorophenyl)ethanol is a high quality reagent for the synthesis of complex compounds, useful as an intermediate in organic synthesis and as a building block for speciality chemicals. This chemical is also used as a research chemical in the synthesis of versatile building blocks. It can be used as a reaction component in various reactions such as Suzuki coupling, Negishi coupling, Heck reaction, and Sonogashira coupling.</p>

<p>Particle size 200-400 mesh</p>

<p>1,3-Bis(dimethylamino)-2-propanol is a polymeric compound that is soluble in water and organic solvents. It has been shown to have a viscosity of less than 2.0 centipoise (cP) at 20°C and pH 8.5. This compound also has a high solubility in buffers, carboxylates, and chloride ions. 1,3-Bis(dimethylamino)-2-propanol has been used as an additive for silicone surfactants and in the production of tetranuclear gold nanoparticles for use in chemiluminescence applications.</p>

<p>4-[(4-Nitrophenyl)-azo]-phenol is a molecular compound that has a nitro group, an azo group, and a phenolic hydroxyl group. It's also known as nitrophenyl diazonium salt. 4-[(4-Nitrophenyl)-azo]-phenol is used in the synthesis of other compounds such as dyes and pharmaceuticals. The magnetic resonance spectroscopy and optical microscope techniques were used to study the chemical structure of 4-[(4-Nitrophenyl)-azo]-phenol. The titration method was used to determine the purity of this compound. 4-[(4-Nitrophenyl)-azo]-phenol has been shown to have mesomorphic properties, which are exhibited by its ability to be either solid or liquid at room temperature (25°C). This property may be due to its functional groups that stabilize it in both states.</p>

<p>2,4-Dimethoxyphenylmethylcarbinol is a benzene derivative that can be synthesized from 2,4-dimethoxybenzaldehyde and formaldehyde. This compound is an efficient reductant for hydrazine and has been used as a screening agent for new drugs. It is also a pharmacological active substance with anti-inflammatory properties. 2,4-Dimethoxyphenylmethylcarbinol has shown activity against carrageenan-induced rat paw edema, as well as the vessel and ultrasonic effects of irradiation.</p>

<p>1-O-Octadecyl-rac-glycerol is a fatty acid that has been shown to have antiinflammatory properties. It is also known as 1,1'-dioctadecyl-rac-glycerol, or DOG. 1-O-Octadecyl-rac-glycerol has been shown to inhibit the production of inflammatory mediators such as prostaglandin E2 and monocyte chemotactic protein 1 (MCP1) in vitro and in vivo. It has also been shown to stimulate the production of colony stimulating factor (CSF), which stimulates the growth and differentiation of stem cells into macrophages, neutrophils, dendritic cells, erythrocytes, and lymphocytes. These cells are needed for wound healing and repair.</p>

<p>Phenethyl glucosinolate potassium salt is a compound found in plants belonging to the Brassicaceae family. It has been shown to be highly toxic to larvae of the cabbage butterfly and other insects that feed on brassica plants. Phenethyl glucosinolate potassium salt has been shown to inhibit the development of these insects, probably by inhibiting protein synthesis in the insect's gut. The major sulfur-containing compound in this product is gluconasturtiin, which has been shown to inhibit growth of pekinensis at high temperatures. This compound also inhibits radiation-induced DNA damage and does not show significant effects on nonsignificant organisms such as yeast and mold.</p>

<p>17-Estradiol-3,17-diol (17-E2) is the most potent estrogen found in humans. It has been shown to be able to stimulate the growth of breast cancer cells and is a known carcinogen in animals. 17-E2 is metabolized by cytochrome P450 enzymes into catechol estrogens, which are reactive and can bind to DNA. These metabolites can cause mutations that lead to cancer. Analysis of human breast tissue has revealed that 17-E2 is synthesized from estradiol by aromatase and then converted into catechol estrogens by 17β-hydroxysteroid dehydrogenase type 1. 17-E2 also binds to estrogen receptors, which may be linked with the development of certain cancers. The presence of 17-E2 in the environment has been linked with an increased risk for cancer in humans, as it can enter the body through water or food contaminated with waste products.</p>

<p>4-Pentyn-1-ol is a molecule with the chemical formula of C10H18O. It has intramolecular hydrogen, hydroxyl group and methyl ketones. 4-Pentyn-1-ol is used as a solvent and in perfumery. This compound can be synthesized by hydrochloric acid, hydrogen bond and proton. The FTIR spectroscopy of 4-pentyn-1-ol shows that it has a broad absorption band at 3300 cm−1 and a sharp peak at 1750 cm−1 which are assigned to the O–H stretching vibrations in the hydroxyl group. The IR spectrum also indicates that this compound has an intramolecular hydrogen bond. 4 pentyn - 1 - ol</p>

<p>Rac-1-anthracen-2-yl-ethanol is an apolar, injecting alcohol. It has two isomers. Rac-1-anthracen-2-yl-ethanol has a selectivity profile that is different from other compounds in its class, and it outperforms amine solvents in the separation of similar compounds. This compound's selectivity profile is due to interactions with the solvent and stationary phase that are unique to this compound. Rac-1-anthracen-2-yl-ethanol also has a low nature and low toxicity profile.</p>

<p>Intermediate in the synthesis of lenvatinib</p>

<p>3,3-Dimethyl-1,2-butanediol is a dioxolane with a constant boiling point of 110°C. This compound is synthesized from the reaction between acetone and formaldehyde, which produces a dioxolane ring. The reaction products can be profiled using gas chromatography to determine the ratio of each product. 3,3-Dimethyl-1,2-butanediol has been shown to have enantiomeric purity of greater than 99%. It has also been used as a chiral building block for the synthesis of carbohydrates with stereospecificity. 3,3-Dimethyl-1,2-butanediol's enzyme catalysis is used in the production of polyesters and polyurethanes.</p>

<p>2-(Difluoromethoxy)Phenol is a purine derivative and pyrimidine derivative. It has been shown to inhibit the growth of cancer cells in vitro and in vivo. 2-(Difluoromethoxy)phenol inhibits multidrug resistance by inhibiting the transport of drugs into cells and thereby preventing their accumulation. As a result, it suppresses inflammatory diseases and autoimmune diseases. The hydroxyl group in this compound can be replaced with fluorine or nitro groups to generate new derivatives with different properties. Piperidine can also be added to this molecule to create an analogue that is more potent than 2-(difluoromethoxy)phenol and has a longer duration of action.</p>

<p>1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[amino(polyethylene glycol) 2000] (ammonium salt) is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[amino(polyethylene glycol) 2000] (ammonium salt) is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

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<p>cis-4-Cyclopentene-1,3-diol is a useful chemical intermediate that can be converted to diacetate, acetylation, or chloroacetate. It has a reactive functional group that can be used for synthesizing polymers and other compounds. cis-4-Cyclopentene-1,3-diol is also an excellent substrate for lipase reactions and it reacts with hydrogen fluoride to give desired products. This section has conformational properties that make it suitable for hydrogen bonding and can act as a ligand in coordination chemistry. cis-4-Cyclopentene-1,3-diol is also able to undergo substitution at the carbonyl carbon atom by various reagents such as fluorine.</p>

<p>2-[3-(S)-[3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl]-3-hydroxypropyl]benzoic acid methyl ester is a synthetic compound that can be used as a reagent in the synthesis of polynucleotides and polypeptides. It can also be used as an inhibitor of ketoreductase, which is an enzyme involved in the synthesis of fatty acids and ketones. 2-[3-(S)-[3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl]-3-hydroxypropyl]benzoic acid methyl ester has been shown to inhibit the growth of wild type and mutant strains of E. coli. The molecular weight of this compound is 439.</p>

<p>3-Methyl-2-nitro-3H-imidazol-4-yl)methanol is a fluorescent probe that can be used to detect hypoxic tumor cells. It has been shown to selectively react with the methylethyl group in Trichomonas vaginalis. 3-Methyl-2-nitro-3H-imidazol-4-yl)methanol is bioreductive and can be activated by nitro groups in proteins, which are found in the active site of enzymes such as bacterial dna gyrase. This probe has been shown to bind to the sn38 position of bacterial DNA, but not mammalian DNA.</p>

<p>1H-Pyrazol-4-ylmethanol is a dehydrogenase inhibitor that binds to the heme group of the enzyme and inhibits oxidative metabolism. It has been shown to be an effective inhibitor of human liver alcohol dehydrogenase (ADH) and also reduces the absorption rate constant of pyrazole derivatives. The catalytic mechanism is not yet known, but it has been found to inhibit other enzymes with a similar catalytic mechanism. Techniques such as kinetic studies and model systems have been used to study this enzyme's catalytic mechanism.</p>

<p>4-Fluoromethyl-alpha-methylbenzyl alcohol is a nonclassical molecule that has been synthesized. This molecule has been modeled computationally and the results indicate that it exhibits a planar geometry with a diastereomeric ratio of 1:1. The theoretical calculations show that the reaction of 4-fluoromethyl-alpha-methylbenzyl alcohol with water is exothermic, which would result in the formation of an intermediate hydroxide ion. Kinetic studies have shown that this molecule can undergo transfer reactions and dehydrogenation reactions, both of which are possible mechanisms for its reactivity.</p>

<p>5-Chloro-8-hydroxyquinoline (5-CQ) is a quinoline derivative that has been used as an anticancer agent. It binds to DNA and inhibits the synthesis of RNA and proteins, leading to cell death. 5-CQ has been shown to be cytotoxic against skin cells in vitro by inhibiting mitochondrial oxidative phosphorylation and decreasing the mitochondrial membrane potential. This compound also has genotoxic effects on cultured choroidal neovascularization cells through the inhibition of DNA synthesis.<br>5-CQ binds to DNA via hydrogen bonds with nitrogen atoms in the purine ring of nucleobases. The overall geometry is that of a distorted octahedron with two faces, each containing six nitrogens in square planar coordination geometry. The binding constants are low for purines but high for pyrimidines, which is why 5-CQ preferentially targets purine rich regions of the genome.</p>

<p>Polymyxin B is a cationic peptide antibiotic that is effective in the treatment of infectious diseases. It has been shown to inhibit growth of Gram-negative bacteria by binding to the outer membrane and disrupting osmotic balance. Polymyxin B has been shown to be toxic to liver cells, but it can be used as an antimicrobial agent in combination with ethylene diamine and clastogenic agents such as hydrochloric acid and hydrogen peroxide. This drug also has genotoxic effects. Polymyxin B has high resistance to hydrolysis by hydroxyl group-containing enzymes, making it a broad-spectrum antimicrobial agent that is active against Gram-positive bacteria, Gram-negative bacteria, and mycobacteria.</p>

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<p>1-O-Hexadecyl-sn-glycerol is a glycol ether that is used as a surfactant and emulsifier in cosmetic products. It has been shown to have minimal toxicity, and to not be carcinogenic or teratogenic. 1-O-Hexadecyl-sn-glycerol has been shown to increase the stability of proteins in rat liver microsomes, and it also prevents the hydrolysis of carbohydrates. The surface glycoprotein adsorbed by 1-O-Hexadecyl-sn-glycerol may play an important role in the binding of monoclonal antibodies. This compound affects cellular calcium levels, with high concentrations resulting in increased cytosolic calcium concentrations. Zirconium oxide can replace calcium ions in 1-O-Hexadecyl-sn-glycerol for this purpose, although this substitution reduces enzyme activity.</p>