Aminas

Applications tert-Butyl 2-Aminobenzoate is a useful reagent for preparing alkylamino quinazolinones.
References Lu, C., et al.: J. Org. Chem., 83, 1154 (2018)

Applications 3,4-Bis(phenylmethoxy)benzeneethanamine is an intermediate used in the synthesis of S-(-)-Tretoquinol Hydrochloride (T798100), which belongs to the class of adrenergic inhalants, selective β-2-adrenoreceptor agonists. S-(-)-Tretoquinol is used in the treatment of obstructive airway diseases. S-(-)-Tretoquinol is a bronchodilator.
References Meshi, et al.: Biochem. Pharmacol., 19, 2937 (1970), Satoh, et al.: Chem. Pharm. Bull., 19, 667 (1971),

Applications Methyl (1R,4S)-4-Amino-2-cyclopentene-1-carboxylate (2S,3S)-2,3-Dihydroxybutanedioic Acid is an intermediate used in the synthesis of ent-Abacavir (A105015), which is an enatiomer of Abacavir (A105000). Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.

Applications 4-Amino-1,1,3-trimethylindane is used as a reagent in the synthesis of (difluoromethylnicotinic)indanyl carboxamides as fungicides useful in crop protection.
References Maechling, S., et al.: PCT Int. Appl. WO 2014095675 A1 20140626. Jun 26, 2014

Applications Dichloramine B (cas# 473-29-0) is a useful research chemical.
E0

Stability Hygroscopic
Applications [3-(3,4-dimethoxyphenyl)propyl](methyl)amine hydrochloride (cas# 83979-31-1) is a useful research chemical.

Applications (benzyloxy)(methyl)amine (cas# 22513-22-0) is a useful research chemical.

Applications 6-​Amino-​5-​nitrochromen-​2-​one is a reagent used in the synthesis of pyranopyridinediones.
References Khan, M. et al.: J. Pure App. Sci., 22, 37 (2004);

Applications N1,N1,N2,N2-Tetrakis(2-aminoethyl)-1,2-ethanediamine is used in the preparation of strong circularly polarized luminescence of rare earth complexes
References Petoud, S. et al.: J. Am. Chem. Soc., 129, 77 (2007); Xu, J., et al.: J. Am. Chem. Soc., 133, 19900 (2011);

Applications Benzyltributylammonium Chloride (cas# 23616-79-7) is a useful research chemical.

Applications 3-DI-N-PROPYLAMINO-1-PROPYNE (cas# 6323-79-1) is a useful research chemical.

Applications 2-{[2-(Dimethylamino)ethyl]methylamino}ethanol is a reagent in the preparation of diamino(aminoalkoxy)quinazolines.
References Liu, F., et al.: J. Med. Chem., 53, 5844 (2010);

Applications (3,3-diethoxypropyl)dimethylamine (cas# 16851-30-2) is a useful research chemical.
References Choi, G., et al.:Angew. Chem. Int. Ed., 57,6166(2018)

Applications Useful in the preparation of substances with antiinflammatory activity.

Applications 2-(methylamino)benzene-1-sulfonamide (cas# 21639-28-1) is a useful research chemical.

Applications 2-Aminobenzylcyanide is a useful reagent for organic synthesis and other chemical processes. It is used in the synthesis of triazolopyridines as a selective JAK1 inhibitors.
References Menet, C. J., et al.: J. Med. Chem., 57, 9323 (2014)

Applications (S)-2-Amino-3-(4-aminophenyl)propan-1-ol is derived from (2S)-2-Amino-3-(4-nitrophenyl)-1-propanol (A618365), which can be used as an intermediate in the synthesis of various pharmaceutical compounds. It is used in the preparation of a new series of 2-substituted thiazole carboxamides as potent inhibitors of Akt kinases.
References Shaohua, Ch., et al.: Bioorg. Med. Chem. Lett., 22, 1208 (2012);

Applications 1,2,4-Triazin-3-amine can be used as integrade inhibiting antiviral agents.
References Kiyama, R., et.al.: PCT Int. Appl.WO 2003016275 A1, 663, (2003);

Applications 5-chloro-2,1,3-benzoxadiazol-4-amine (cas# 80277-04-9) is a useful research chemical.

Applications 2-(4-Amino-2-ethoxyphenyl)pthalimide (cas# 106981-52-6) is a compound useful in organic synthesis.

Pyrimidin-4-ylmethyl)amine dihydrochloride is a drug that belongs to the class of drugs known as kinase inhibitors. Pyrimidin-4-ylmethyl)amine dihydrochloride inhibits the kinase activity of Jak3, which is involved in regulating inflammation and immune response. This inhibitor has been shown to be effective against chronic inflammatory diseases such as asthma, psoriasis, and rheumatoid arthritis. Pyrimidin-4-ylmethyl)amine dihydrochloride has an affinity for ATP binding sites and can be used to regulate kinase activity by competing with ATP for these binding sites.

3,5-Diamino-2,4,6-trimethylbenzenesulfonic acid (DTMS) is an aromatic hydrocarbon that has been found in the environment. DTMS is used as a chlorine scavenger in water treatment plants and wastewater treatment facilities to remove chlorinated organics from the water. It has been shown to be a ligand for uranium. DTMS reacts with cyanuric acid to form 3,5-dichloro-2,4,6-trimethylbenzenesulfonyl chloride (CAS No. 52834-57-1). DTMS also exhibits affinity for metal ions such as copper and nickel.

2-Amino-5-bromobenzonitrile is a bioactive substance that belongs to the class of amines. It is used as an intermediate in the production of other industrial chemicals, such as polyurethanes and polyamides. 2-Amino-5-bromobenzonitrile can be found in faeces at a concentration of approximately 1 µg/g. The metabolic pathway for 2-amino-5-bromobenzonitrile has been shown to be cyp3a5 dependent.

Diethylamine hydrochloride is a chemical compound that is used as an intermediate in the manufacture of other chemicals. It can be used to treat metabolic disorders such as diabetes, hypothyroidism, and osteoporosis. Diethylamine hydrochloride has been shown to inhibit group P2 phosphodiesterases (PDEs) and prevent their degradation by the enzyme dipeptidyl peptidase-IV (DPP-IV). This inhibition leads to increased levels of cyclic AMP in cells, which contributes to its anti-inflammatory activity. The structural analysis of diethylamine hydrochloride has been performed using x-ray diffraction data and x-ray crystal structures.

4-Amino-2-(1,3-benzoxazol-2-yl)phenol (4APB) is a fluorescent compound that has been used to study the fungal cell wall. It has shown to cause morphological changes in the conidia of some fungi, including transfer and swelling of the contents. 4APB has also been used to study the transfer mechanism of conidia by fluorescence microscopy and epifluorescence microscopy. This chemical can be stained with tosylates, which are reagents used for staining proteins and other molecules that contain sulfur atoms.

2-Amino-1,3,5-triazine is a hydrogen bond donor that has been shown to have growth inhibiting effects. It reduces the viscosity of aqueous solutions and is used as an enantiopure for amines. 2-Amino-1,3,5-triazine can be used in reactions with metal surfaces to produce surface coatings or used as a bifunctional crosslinking agent for polymer materials. 2-Amino-1,3,5-triazine has been shown to have degenerative disease inhibitory activity and inflammatory disease inhibitory activity. It also inhibits the production of inflammatory cytokines such as tumor necrosis factor alpha (TNFα) and interleukin 6 (IL6).