Ciano-, nitrilo-

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Applications tert-Butyl 3-Cyanomorpholine-4-carboxylate is used as a reactant for the synthesis of HIV integrase inhibitors.
References Gardelli, C., et. al.: J. Med. Chem., 50, 4953 (2007); Pace, P., et. al.: J. Med. Chem., 50, 2225 (2007); Summa, V., et. al.: J. Med. Chem., 49, 6646 (2006)

Applications Tetrakis(acetonitrile)palladium Bis(tetrafluoroborate) is used to prepare an α-Diimine-transition metal complex, which is used as a catalyst for polymerization of olefins. It is also a catalyst used in cross coupling reaction for C-C, C-O, and C-N bond formation.
References Feldman, J., et al.: Organometallics, 16, 1514 (1997); Johnson, L., et al.: PCT Int. Appl., WO 9623010 A2 19960801 (1996); Poppenbery, J., et al.: Surface Sci., 2011; Pijnenburg, N., et al.: Dalton Transactions, 40, 8896 (2011); Kilpin, K., et al.: Inorg. Chem., 50, 6334 (2011)

Applications 4-Biphenylacetonitrile is a useful synthetic intermediate. It was used to study the adsorption orientation of the biphenyl derivatives on the Au colloidal surfaces with α-cyclodextrins. 4-Biphenylacetonitrile on condensation reaction with ethyl phenyl propiolate yields biphenyl derivatives of acetylenic β-ketocyanide.
References Lee, J., et al.: Bull. Korean. Chem. Soc., 30, 1637 (2009); Al-Jallo, H., et al.: J. Chem. Eng. Data, 17, 513, (1972)

Applications A Wittig reagent.
References Laine, D., et al.: J. Med. Chem., 52, 5241 (2009), Nakao, A., et al.: Bioorg. Med. Chem. Lett., 19, 4607 (2009), Arakawa, Y., et al.: Chem. Pharm. Bull., 57, 167 (2009),

Applications 3-Nitrobenzoylacetonitrile (cas# 21667-64-1) is a useful research chemical.

Applications (3,5-Dimethoxyphenyl)acetonitrile (cas# 13388-75-5) is a compound useful in organic synthesis.

Applications N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-oxopropanamide (cas# 87310-69-8) is a compound useful in organic synthesis.

Applications Methyl 5-cyano-2-fluorobenzoate

Applications (2-Isocyanoethyl)-benzene is a useful synthetic intermediate. It is a reagent used in Ugi reactions to synthesize various compounds such as tetrazole and bisamide.
References Zhao, T., et al.: Org. Lett., 15, 639 (2013); Brockmeyer, F., et al.: Helv. Chim. Acta., 95, 1857 (2012)

Applications 4-Benzyloxyphenylacetonitrile is an intermediate in the preparation of Desmethylvenlafaxine, an antidepressant and also in the preparation of RAGE antagonist for the treatment of Alzheimer's disease.
References Zhao, J., et al.: Zhongguo Yiyao Gongye Zazhi, 45, 601 (2014); Lee, Y. S., et al.: Bioorg. Med. Chem. Lett., 22, 7555 (2012)

Applications Tert-butyl 3-amino-4-cyanobenzoate is a useful compound for organic synthesis.

Applications p-Cyanobenzoic Acid Trimer is used in the synthetic preparation of Terbium Triazinetribenzoate Formate Metal Organic Framework (MOF).
References Han, Y., et al.: J. Mater. Chem. A Mater. Energy Sustain., 3, 24525 (2015)

Applications 4-cyano-N,N-dimethylbenzamide (cas# 24167-50-8) is a useful research chemical.

Applications 4-(Cyanophenyl)boronic Acid Pinacol Ester is used to prepare arylparacyclophanes via Suzuki aryl cross-coupling of bromoparacyclophane with arylboronic acid and arylboronates. It’s also used to prepare tyrosine-modified analogs of α4β7 integrin inhibitor biotin-R8ERY.
References Roche, A., et al.: Org. Biomol. Chem.,, 3, 515 (2005); Papst, S., et al.: Bioorg. Med. Chem., 20, 5139 (2012)

Applications Methyl 3-Cyanoropionate is used in the preparation of anticancer agents. Also used in the design of the ‘dipeptoid’ analogs of cholecystokinin.
References Graham, L. et al.: J. Med. Chem., 55, 7817 (2012); Boden, P. et al.: Eur. J. Med. Chem., 28, 47 (1993);

Applications Methyl 2-cyanobenzoate

Applications An intermediate for insecticide.
References Cole, L., et al.: Pestic. Biochem. Physiol., 46, 47 (1993), Cole, L., et al.: Life Sci., 56, 757 (1995), Hosie, A., et al.: Br. J. Pharmacol., 115, 909 (1995),

Applications 4-CYANO-4-[(ETHYLSULFANYLTHIOCARBONYL)SULFANYL]PENTANOIC ACID (cas# 1137725-46-2) is a useful research chemical.

Applications 4-Cyanocyclohexanone is used to prepare nicotinamides as PDE4 D isoenzymes inhibitors. It is also used as an anthranilic acid replacement in niacin receptor agonist.
References Marfat, A., et al.: PCT Int. Appl. (1998), WO 9845268 A1 19981015; Schmidt, D., et al.: Bioorg. Med. Chem. lett., 20, 3426 (2010)

Applications 2-Acetyl-4-cyanophenol

Applications Pentachlorophenyl Cyanoacetate is an intermediate used in the synthesis of Cefacetrile (C231500), which is a cephalosporin antibiotic. Antibacterial.
References Dajan, A., et al.: Vet. Microbiol., 35, 213 (1993), Becker, M., et al.: Anal. Chim. Acta, 520, 19 (2004), El-Shaboury, S., et al.: J. Pharm. Biomed. Anal., 45, 1 (2007),

Applications BENZYL CYANOMETHYLCARBAMATE (cas# 3589-41-1) is a useful research chemical.