Éteres

2,5-Dimethoxybenzamide is a potent inhibitor of the enzyme DECATENASE. This enzyme plays an important role in the biosynthesis of the aromatic amino acids phenylalanine and tyrosine. 2,5-Dimethoxybenzamide has been shown to have anticancer activity in vitro and in vivo. Remoxipride is a synthetic drug that competitively inhibits the action of benzodiazepines on GABA receptors by binding to them with high affinity. It was developed as an antipsychotic agent but was never marketed for this indication due to its adverse effects on motor coordination. Remoxipride has also been shown to have estrogenic activity, which may be due to its ability to bind with high affinity and inhibit the enzyme aromatase, which converts testosterone into estradiol.

3,4-Dimethoxybenzanilide is a synthetic compound that can be synthesized from dimethyl ether and carboxylic acid. It is an amide of 3,4-dimethoxybenzoic acid and can be hydrogenolysed to yield the corresponding carboxylic acid. The lithiated derivative of 3,4-dimethoxybenzanilide has been used in the synthesis of a number of compounds including amides, lithiated derivatives, and dithiocarbamates. This chemical has also been used in the synthesis of a number of advances such as new carboxylic acids and aldehydes.

4-Methoxy 17β-estradiol is a synthetic estrogen that is used as a pharmaceutical drug in the treatment of menopausal symptoms and to prevent osteoporosis. It can be taken orally or administered by injection. 4-Methoxy 17β-estradiol has been found to have interactive effects with other drugs, such as fatty acids and catechol-o-methyltransferase (COMT). It also has an effect on body mass index in vivo, which can lead to cancerous cell proliferation. The matrix effect of 4-methoxy 17β-estradiol on tissues depends on the hydrogen bonds it forms with amino acids in the protein matrix. The hydrogen bonds are different for each tissue type and this may contribute to the differences in carcinogenic potential between tissues. This drug is not active against MCF-7 human breast cancer cells, but does inhibit growth of MDA MB 231 human breast cancer cells.

2,4,5-Trimethoxybenzyl alcohol is a metabolite that is produced by the p. pastoris strain. It has been shown to be active against the enzyme glyceraldehyde-3-phosphate dehydrogenase and has been expressed heterologously in yeast. 2,4,5-Trimethoxybenzyl alcohol also has been shown to inhibit peroxidases and may have biochemical applications in pharmaceuticals as an inhibitor of lipid peroxidation.

2-Amino-3-methoxybenzoic acid hydrochloride is a synthetic monosubstituted hydroxy analog of the natural alkaloids, which are substituted with an amino group. It is produced by the demethylation of 2-amino-3-hydroxypyridine and reacts with caprolactam to form 2,6-dihydroxybenzaldehyde. It has been used in the synthesis of methoxyanthranilic acid, which is a synthetic analogue of anthranilic acid. Hydrochloric acid can be added to 2-amino-3-methoxybenzoic acid hydrochloride to produce 2,6-dihydroxybenzoyl chloride. This compound also undergoes condensation reactions with methoxyanthranilic acid to form 2,6-dimethoxybenzaldehyde.

2,2-Difluoro-2-[1,1,2,2-tetrafluoro-2-(trifluoromethoxy)ethoxy]-acetic acid is a fluorinated compound that can be used as an adsorbent for organic compounds. It is a highly selective material and has high adsorption capacity. The adsorption equilibrium data for 2,2-difluoro-2-[1,1,2,2-tetrafluoro-2-(trifluoromethoxy)ethoxy]-acetic acid are given in the table below. Table: Adsorption Equilibrium Data Temperature (°C) Pressure (kPa) Vapor Pressure (Pa) Equilibrium Vapor Pressure (Pa) Adsorption Capacity (%) 0 0.001 0.0008 0.0012 100

4-Amino-5-chloro-2-ethoxybenzoic acid is a phenoxy compound that is synthesized in the laboratory. The chemical structure of this compound has been studied using high performance liquid chromatography and it was found to have pharmacokinetic properties that are consistent with those of other drugs in its class. This drug is being developed as an anti-depressant, targeting the 5HT4 receptor. The bioactive metabolite of 4-amino-5-chloro-2-ethoxybenzoic acid is 4-(4′ hydroxybutyl)phenol, which has been shown to be a potent inhibitor of phosphodiesterase activity.

5-Amino-3-(4-methoxyphenyl)pyrazole (5AMPAP) is an anti-cancer agent that is effective against a number of different cancers, including breast, lung, and prostate. It selectively inhibits the growth of cancer cells by targeting enzymes in the mitochondria that are required for ATP production. 5AMPAP binds to the enzyme pyruvate dehydrogenase kinase, which has been shown to be involved in regulating cell proliferation and apoptosis. In addition, it has been demonstrated that this compound has anti-inflammatory properties. The regioselectivity of 5AMPAP was determined by x-ray crystallography and was found to form a pyrazolopyrimidine ring with two nitrogens on opposite sides of the ring. This regioselectivity is necessary for its anti-cancer activity.

5-Bromo-2-methoxytoluene is a bromoarene that reacts to form aziridines and phosphotungstic acid. It is used in the synthesis of polyaromatic compounds with steric interactions. 5-Bromo-2-methoxytoluene is also a functional group that can be used as an allosteric modulator. This compound also has stereoisomers that are chiral, meaning they have different structures despite being mirror images of each other. The carbonyl group on the 5-bromo compound is polar, which means it has a charge. The hydrogen bonds between this compound and other molecules are nonpolar, which means they do not have a charge and are more likely to form in a nonpolar solvent.

3,4,5-Trimethoxybenzyl cyanide is a natural product that has been shown to inhibit the polymerase of bacterial RNA and DNA. It binds to the active site of the enzyme and prevents its function. The mechanism of 3,4,5-trimethoxybenzyl cyanide is similar to that of other inhibitors of bacterial RNA polymerase such as quinacrine and actinomycin D. This compound has also been shown to prevent fibrillation in vitro. 3,4,5-Trimethoxybenzyl cyanide has antiarrhythmic properties. It blocks the mitochondrial membrane potential by inhibiting the synthesis of ATP. This inhibition leads to an increased permeability of the mitochondrial membrane for ions such as potassium and calcium. The increased permeability leads to a decrease in cellular excitability and a decrease in cardiac arrhythmias (irregular heartbeats).

1-(3-Benzyloxy-4-methoxyphenyl)-2-nitroethene (1BMN) is an ethanamine that has a skeleton of five benzene and one methoxybenzene rings. It is an analogue of lamellarin, which has been shown to have efficient synthetic and biological properties. 1BMN is biologically active as a lamellarin analog and may be useful for the treatment of diseases such as cancer, malaria, hypertension, hyperglycemia, hypercholesterolemia, and ulcerative colitis. 1BMN is synthesized from 2-nitroethanol by reacting with 3-bromobenzaldehyde in the presence of sodium hydroxide. This reaction results in the formation of 1BMN in high yield with few side reactions.

(R)-(+)-2-Methoxypropionic acid is a derivatization agent that is used to label branched-chain amino acids. It has been shown to react with l-rhamnose, which is found in glycoproteins and polysaccharides.

2-Methoxy benzyl chloride is an organometallic compound that has potent antagonist activity against a wide variety of organometallic and non-organometallic compounds. It is used in the treatment of inflammatory diseases, such as myocardial infarct, and also displays antimicrobial properties. 2-Methoxy benzyl chloride is a potent competitive inhibitor of many enzymes, including xanthine oxidase, hydroxylase, and tyrosinase. This molecule also has the ability to bind to cationic polymers and inhibit polymerization reactions by interfering with the formation of hydrogen bonds between monomers. The chlorine atom in this molecule can be replaced by a hydrogen atom for use as an antimicrobial agent. 2-Methoxy benzyl chloride binds to nitrogen atoms on amides and other nitrogen containing compounds, which may account for its antiinflammatory effects.

2,3,4,5-Tetramethoxytoluene is a chlorinated aromatic hydrocarbon that is produced by the chloromethylation of toluene. It can be used in the synthesis of isoquinoline compounds and grignard reagents. 2,3,4,5-Tetramethoxytoluene is also a precursor for the production of 2-chloro-1-(2-chlorophenyl)ethanol (CCPE), which is used as an intermediate for the production of various pesticides and herbicides. Tetramethoxytoluene has been shown to be toxic to fish in water at concentrations as low as 0.1 micrograms per liter. It also has a potential to cause environmental pollution because it reacts with peroxide and alkylates other organic compounds.