Aldehídos

N-Boc-2-aminoacetaldehyde is an aliphatic aldehyde that has been used in the synthesis of a number of bioactive molecules. It is synthesized by reacting an N-Boc amino acid with chloroform and hydrochloric acid. The reaction time is typically 2 hours at room temperature, although it can be decreased to 20 minutes if the temperature is increased to 60°C. The product can be purified using extraction or recrystallization methods. N-Boc-2-aminoacetaldehyde reacts with chloride ions to form phosphoranes, which are useful in clinical development as antimicrobial peptides. This compound also reacts with fluorine to form hydrogenated derivatives that have been shown to have neurokinin activity in animal models.

2-Bromo-6-methylpyridine-3-carboxaldehyde (BMPCA) is a pharmacological agent that belongs to the group of antagonists. It has been shown to be a potent antagonist at the NMDA receptor and may be used for treating neuropathic pain. BMPCA also has been shown to have competitive inhibition at the naphthyridine receptor, which may allow it to act as an antagonist or an agonist depending on its binding site. The regioisomeric analogs of BMPCA are 2-(2,5-dichloropyridyl)-6-methylpyridine-3-carboxaldehyde and 2-(2,5-dimethylpyridyl)-6-methylpyridine-3-carboxaldehyde. These analogs have been shown to inhibit the growth of tumor cells in vitro and in vivo.

1H-Pyrazole-4-carbaldehyde is a chemical compound that inhibits the growth of bacteria by binding to the enzyme ribonucleotide reductase. It has been shown to have significant antifungal activity against Candida albicans and Saccharomyces cerevisiae, as well as in vitro antifungal activity against other fungi. The 1H-pyrazole-4-carbaldehyde has also been found to inhibit xanthine oxidase and nitric oxide synthase (NOS) in vitro and in vivo, which may be due to its ability to reduce oxidative stress. This chemical compound is a coumarin derivative and contains a pyrazole ring.

2-Bromo-5-chlorobenzaldehyde is an industrial chemical that is used as a precursor for the production of other chemicals. It can be synthesized by reacting 3-chlorobenzaldehyde with sodium bromide in the presence of a catalyst. 2-Bromo-5-chlorobenzaldehyde has been shown to have high reactivity, and can be used as a catalyst to produce large amounts of organic compounds. This chemical can also be produced in large quantities by neutralizing alkalis with acid, which is an effective way to dispose of these hazardous substances.

4-Fluorobenzaldehyde oxime is a phenylhydrazine derivative that reacts with an aromatic amine to form a ternary complex. The reaction time for this process is short, and the yield of the product is high. 4-Fluorobenzaldehyde oxime also reacts with an aromatic amine to form an ion-pair. It can react with acidic hydrogen donors such as peracids and it also has high hydrogen bonding interactions. 4-Fluorobenzaldehyde oxime is used in pharmacological agents as well as other chemical reactions, including halogenation.

3-Fluoro-2-nitrobenzaldehyde is a pyridine derivative that has been used in the synthesis of a number of important heterocyclic compounds. This compound can be prepared by reacting 3,4-dichloroaniline with nitrous acid and then hydrolyzing the resulting 3-chloroquinoline with hydrochloric acid. The reaction yields anilines and quinolines in regiospecifically, as well as formylation, cyclisation, and condensation products. It is also capable of aromatisation reactions with benzene to produce benzofuran derivatives.

Prodrug of ACE inhibitor MK-422

4-Chloro-3-fluorobenzaldehyde is an atypical molecule that has a deuterium atom. It is classified as a group p2 functional theory reuptake inhibitor, which blocks the reuptake of noradrenaline at the synapse. The vibrational and spectroscopic properties of this molecule are similar to those of other molecules in its class. 4-Chloro-3-fluorobenzaldehyde was shown to inhibit the production of noradrenaline in rat brain tissue and is used as a model for studying genetic polymorphism. Techniques such as nuclear magnetic resonance spectroscopy, infrared spectroscopy, and X-ray crystallography have been used to investigate the structure and reactivity of 4-chloro-3-fluorobenzaldehyde.

2-Methyl-5-nitrobenzaldehyde is a nitro compound that is used in the synthesis of dobutamine. It has been shown to undergo rearrangements, with the formation of 2-methyl-5-nitrophenol. Kinetic studies have shown that chlorine can be substituted for hydrogen at the 2 position, and this substitution leads to an increase in reactivity. 2-methyl-5-nitrobenzaldehyde also reacts with dopamine to form a ketone. The hydroxy group on this molecule is nucleophilic and can attack electrophiles, making it useful as an active site for synthetic reactions. This compound is also pyrophoric, which means it will spontaneously ignite in air and burn until all its fuel is consumed.

2,3,5-Trichlorobenzaldehyde is a chemical compound that has been shown to have anticancer and apoptotic effects. It inhibits the growth of bacteria by chelating iron ions and inhibiting bacterial dna synthesis. 2,3,5-Trichlorobenzaldehyde has also been shown to inhibit the growth of cancer cells in culture in an experimental study. This chemical has been used as a substrate for nmr spectroscopy to study its functional groups and radical scavenging activities. 2,3,5-Trichlorobenzaldehyde can be synthesized from phenacyl chloride and benzaldehyde in the presence of hydrogen chloride gas. The carbonyl group in 2,3,5-trichlorobenzaldehyde may cause metabolic disorders such as diabetes mellitus or hyperglycemia.

Perillaldehyde is a natural compound that has been used in food and medicine for centuries. It is an antimicrobial agent with dextran sulfate, which is a sugar polymer that inhibits the growth of fungi and bacteria. Perillaldehyde also has been shown to inhibit the energy metabolism of microorganisms by decreasing ATP production. Perillaldehyde has also been shown to have genotoxic activity, as it can cause DNA strand breaks. This compound also causes oxidative stress in cells by reducing mitochondrial membrane potential and inducing reactive oxygen species (ROS). Perillaldehyde has acute toxicities, as it causes electrochemical impedance spectroscopy changes that indicate cell death.

3-Nitroisonicotinaldehyde is a kinase inhibitor that binds to the ATP binding site of receptor tyrosine kinases. It inhibits the activation of these receptors and prevents the phosphorylation of tyrosine residues on the receptor. 3-Nitroisonicotinaldehyde has been shown to inhibit VEGFR-2, ABCG2, and efflux in human cancer cells. This drug has been shown to inhibit tumor growth in mice by inhibiting angiogenesis, which is a process that involves the formation of new blood vessels from pre-existing ones. 3-Nitroisonicotinaldehyde also inhibits tumor growth by blocking the production of vascular endothelial growth factor (VEGF) from angiogenic cells.

3-Bromo-4-methoxybenzaldehyde is a heterocycle that contains a covalent inhibitor. It has been shown to have inhibitory activity against imines, hydroxyl groups, and human serum. 3-Bromo-4-methoxybenzaldehyde has been shown to be an efficient method for the synthesis of nitrogen containing heterocycles with potential use as pharmaceuticals. This compound has also been used in the asymmetric synthesis of diphenyl ethers, which are useful in pharmacological studies. The reaction mechanism of this compound is not well understood and needs more research before it can be applied to other areas.

3-Nitrobenzaldehyde is an organic compound that is used in the synthesis of monoclonal antibodies for use in cancer research. It has been shown to have genotoxic and carcinogenic effects, as it binds to nucleic acids and inhibits DNA replication. 3-Nitrobenzaldehyde has been shown to be effective against a variety of bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and Clostridium perfringens. This compound also inhibits protein synthesis by binding with amines and hydrogen bonding with the amino acid residues of proteins.

2-Phenylindole-3-carboxaldehyde is an organic compound that belongs to the class of bioactive molecules. It is a nitrogen heterocycle that has been shown to inhibit the growth of cancer cells in culture. 2-Phenylindole-3-carboxaldehyde has also been shown to have anti-inflammatory and antimicrobial properties. This molecule can be used in the treatment of cancer, as it inhibits the growth of tumor cells by inhibiting DNA synthesis, which leads to cell death. The molecular structure can be altered by allylation or replacement with other functional groups. The 2-phenylindole moiety can be modified at its C2 position, altering its pharmacological properties and may lead to new anticancer drugs.

1-Naphthaldehyde is a coordination compound that contains 1 naphthyl group and an oxygen atom. It can be used as an oxidation catalyst, intramolecular hydrogen, or a reaction solution. The antimicrobial activity of 1-naphthaldehyde has been shown in the presence of sodium carbonate or potassium phosphate buffer. 1-Naphthaldehyde has been shown to possess structural properties similar to those of other metal chelates, such as zinc pyrithione. The protonated form of 1-naphthaldehyde has been identified by means of analytical methods including gas chromatography and mass spectrometry.

2-Bromo-3,6-difluorobenzaldehyde is a versatile building block that is used in the synthesis of many complex compounds. It has been shown to be a useful intermediate and reaction component in organic synthesis. 2-Bromo-3,6-difluorobenzaldehyde can be used as a reagent or speciality chemical for research purposes. This compound has high quality and is a useful scaffold for the preparation of fine chemicals.

Applications 8-Nonenal is used as a reactant in the preparation of macrocyclic Z-enoates and (E,Z)- or (Z,E)-dienoates through catalytic stereoselective ring-closing metathesis.
References Zhang, H., et al.: JACS., 136, 16493 (2014)

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