Piridinas

<p>Applications Lidamidine is an intermediate in the synthesis of Lidamidine Hydrochloride which is a novel antidiarrheal agent that has potent antimotility, antidiarrheal and antisecretory activity. It also significantly reduces the total number of bowel movements and the loss of liquids in healthy people with senna-induced diarrhea.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Martin, Luis., et al.: IRCS Med. Sci., 9(11), 1052-3 (1981); Krebs, J. B., et al.: Arzneimittel-Forsch., 31(8), 1251-4 (1981); Mir, G. N., et al.: Arzneimittel-Forsch., 28(8A), 1448-54 (1978)<br></p>

<p>Applications Pyridazinone derivatives are useful as intermediates for preparing compounds having excellent herbicidal activity.<br>References Hackler, et al.: J. Agric. Food Chem., 38, 508 (1990)<br></p>

<p>Applications (4-Methoxy-3,5-dimethylpyridin-2-yl)methanol (cas# 86604-78-6) is a useful research chemical.<br></p>

<p>Applications 2-Methylpyrazolo[1,5-a]pyrimidine-6-carboxylic Acid is a reactant used in the preparation of DPP-IV inhibitors.<br>References Kato, N., et. al.: Bioorg. Med. Chem, 19, 7221 (2011)<br></p>

<p>Applications A metabolite of Dopamine analogs.<br>References Goodwin, B.L., et al.: Xenobiotica, 24, 129 (1994), Berry, M., et al.: J. Neurochem., 90, 257 (2004), Miller, G., et al.: J. Pharmacol. Exp. Ther., 313, 983 (2005), Reese, E., et al.: J. Pharmacol. Exp. Ther., 321, 178 (2007),<br></p>

<p>Applications 2-Aminopyrazine-5-carboxylic Acid Methyl Ester (cas# 13924-94-2) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-Pivaloylamino-3-(α-hydroxybenzyl)pyridine (cas# 86847-67-8) is a compound useful in organic synthesis.<br></p>

<p>Applications 3β-Hydroxy-5α-pregnan-20-one Sulfate Pyridine Salt is an intermediate in the synthesis of (3β)-Allopregnanolone Sulfate (A547125), a metabolite of progesterone and a potent inhibitory modulator of GABAA receptors.<br>References Paterson, J.Y.F., et al.: Biochem. J., 43, 614 (1948);<br></p>

<p>Applications 2-(Phenylamino)nicotinic Acid (cas# 16344-24-4) is a useful research chemical.<br></p>

<p>Applications 2-Amino-5-ureido-4,6-pyrimidinedione (cas# 21823-25-6) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-Chloro-4-ethylpyridine (cas# 40325-11-9) is a compound useful in organic synthesis.<br></p>

<p>Stability Not Stable in Solution<br>Applications 4-Amino-5-[(dithiocarboxyamino)methyl]-2-methypyrimidine Ammonium Salt is an intermediate in the synthesis of Thiamine (T344185), an essential nutrient required for carbohydrate metabolism; also involved in nerve function.<br>References Kawaski, T., et al.: Methods Enzymol., 122, 15 (1986), Mascher, H., et al.: J. Pharm. Sci., 82, 56 (1993),<br></p>

<p>Stability Light Sensitive<br>Applications 4-(1-Naphthylvinyl)pyridine (cas# 16375-56-7) is a useful research chemical.<br></p>

<p>Applications 3-Hydroxymandelonitrile (cas# 53313-95-4) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Stability Hygroscopic<br>Applications A tobacco-specific nitrosamine adduct and metabolite of NNK, 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone.<br>References Kutzer, C., et al.: J. Chromatog. Sci., 35, 1 (1997), Prodhomme, E., et al.: Bioconjug. Chem., 18, 2045 (2007), Hoelzle, D., et al.: Toxicol., 232, 277 (2007), Hecht, S., et al.: Chem. Res. Toxicol., 20, 543 (2007),<br></p>

<p>Applications 4-Acetamidobenzyl Alcohol is a useful research chemical, a metabolites of a blocked chloramphenicol producer.<br>References Lewis, E. A., et al.: J. Nat. Prod., 66, 62 (2003)<br></p>