Fenoles

Gingerenone A, an Nrf2-Gpx4 activator isolated from ginger, has anticancer activity and inhibits iron death in mice with colitis secondary to liver injury (SLI)

m-Tyramine hydrobromide (3-(2-aminoethyl)phenol hydrobromide) is a dopamine derivative that acts by releasing newly synthesized catecholamines or 5-HT.

Cis-Vitisin B is a hydroxystilbene analog found in the roots of the plant Kyohou.

Gallic Acid Monohydrate, a natural polyhydroxyphenol, which inhibits the free radical scavenging effect of COX-2,antioxidant, anti-tumor, and antibacterial.

Rhaponticin(Rhaponiticin) has a noticeable antidiabetic effect and could be potentially used as a new agent to treat type 2 diabetes mellitus and its complications, it can alleviate liver steatosis and improve blood glucose and lipid profiles in KK/Ay diabetic mice.

Lasalocid (Lasalocid-A) is an ion carrier antibiotic produced by Streptomyces, which has antimicrobial and parasitic properties and is often added to feed.

Prim-O-glucosylcimifugin is main medicinal component of the traditional Chinese drug Saposhnikovia divaricata, can increase concentrations of astragaloside IV and atractylenolide I in the serum, when they were given together.

Hericene A (Hericium erinaceus A) is a natural product that inhibits viability of HCT116 cells and can be used in biochemical experiments and drug synthesis.

Bergenin is a potent antinarcotic agent, has antiviral ,antifungal, antiarrhythmic, antitumor, antiinflammatory, potent immunomodulatory, antitussive, antiulcerogenic,anti-plasmodial, anti-hepatotoxic and wound healing activities. Bergenin has antidiabetic activity, could be classified as a new group of α-glucosidase inhibitors. Bergenin reduces the expression of NO, TNF-α, IL-1β, and IL-6 proinflammatory cytokines by inhibiting the activation of the NF-κB and MAPKs signaling pathways, and it may represent a novel treatment strategy for mastitis.

10-Shogaol, as an antioxidant for human skin cell growth and a migration enhancer with potential to be a novel wound repair agent.8- and 10-Shogaol have similar metabolic profiles to -shogaol and exhibit similar toxicity toward human colon cancer cells.

Punicalin exerts anti-inflammatory, antioxidative, and anti-hepatotoxic activities, it shows inhibitory activity on HIV-1 reverse transcriptase in a dose-dependent manner, with an IC50 of 0.11 microg/ml (0.14 microM).

6-Shogaol, an active constituent of ginger, is a potent inhibitor of MDA-MB-231 cell invasion, and the molecular mechanism involves at least in part the down-regulation of MMP-9 transcription by targeting the NF-κB activation cascade, thus has potential for clinical use as antimetastatic treatments.