Glycoscience

<p>GD2 oligosaccharide is the core trisaccharide structure of the ganglioside GD2 (sodium salt) (GalNAcβ1,4Galβ1,4Glc) with its two sialic acids linked α2,3/α2,8 to the central galactose residue (Ledeen, 2009). GD2 ganglioside is expressed at a low concentration in the central nervous system, nerves, skin melanocytes and stem cells in healthy adults. On the other hand, GD2 ganglioside is overexpressed in a number of tumors, including: neuroblastoma, melanoma, small cell lung carcinoma and brain tumors. Recently, GD2 ganglioside has been found in low concentrations on breast cancer stem cells (CSC) that possess: self-renewal properties (division without disrupting the undifferentiated state) and tumor-initiating capabilities. It has been suggested that GD2 ganglioside may be developed as an effective target antigen for CSC immunotherapy (Fleurence, 2017).</p>

D-Xylo-Pentodialdose-5-hydrate is a custom synthesis that is used for the preparation of oligosaccharides and polysaccharides. It is an active form that is synthesized by the fluorination of D-xylose. The monomeric sugar penta-D-xylo-D-galactopyranoside has a molecular weight of 259.28 g/mol and a purity of >99%. This compound has been modified in order to increase its activity.

<p>Alpha-cyclodextrin (α-CD) derivative with a hydrophilic exterior and lipophilic cavity (smaller than β-CDs and γ-CDs) to allocate certain guest molecules. This structural characteristic enables applications in molecular encapsulation, solubility enhancement, and stabilization across multiple industries. In pharmaceuticals, it serves as a drug delivery vehicle, enhancing the bioavailability and stability of active ingredients. The food industry utilizes it as a stabilizer for flavors, colors, and nutrients, as well as a functional ingredient for its effects on lipid metabolism. In cosmetics, it acts as a complex agent for fragrances and active components. Its applications extend to analytical chemistry for chiral separation and to materials science for developing smart materials and nanosystems.</p>

<p>1,1-Di-C-allyl-2-O-benzyl-3,4-di-O-isopropylidene-2,4-di-C-methyl arabinopyranose is a methylated saccharide that has been synthesized by Click chemistry. It is a custom synthesis with high purity and high yield. 1,1 Di C allyl 2 O benzyl 3 4 di O isopropylidene 2 4 di C methyl arabinopyranose can be used as an artificial sweetener or as a sugar substitute in food products. This product can be modified to suit the needs of the customer.</p>

2-Amino-2-deoxy-D-talose (2ADDT) is an intermediate in the synthesis of 2,3:4,5-di-O-acetylideneamino-2,3:4,5-di-O-methylideneamino D -talose. It is obtained by the hydrolysis of 2,3:4,5-di-O-acetylideneamino D -talose with hydrochloric acid and methanol. The product is a white solid that can be purified by recrystallization from water or ethanol. 2ADDT can be converted to 2,3:4,5-di - O - acetylideneamino D - talose by treatment with sodium methoxide in methanolic solution. 2ADDT also reacts with nitromethane in methanolic solution to produce d - lyxose and 1 deoxy 1 nitro

<p>Sialyl-3-fucosyllactose is a monosaccharide that is a component of the sialyl-Lewisx oligosaccharide. The il-2 receptor binds to this oligosaccharide, which is involved in energy efficiency. 3'-Sialyl-3-fucosyllactose has been linked to cancer resistance and gene product production. It has also been found to be an important dietary nutrient for animals and humans. 3'-Sialyl-3-fucosyllactose plays an important role in the growth of cells, especially those that have been damaged or are undergoing apoptosis. It also has neurotrophic effects, which are beneficial for the development of neurons and brain function. Body mass index (BMI) is also known to be related to 3'-sialyl-3-fucosyllactose levels in plasma.</p>

<p>NGA3 Glycan, 2-AB labelled is an oligosaccharide that is a complex carbohydrate. It is a polysaccharide that contains saccharides, which are sugars. The saccharides in this compound are monosaccharides, which are single sugar units. This compound has been modified and can be used for the detection of methylation.</p>

1,6-Anhydro-b-D-cellopentose is a synthetic cello-oligomer

4-Azido-4-deoxy-D-glucose (4A4DG) is a potential inhibitor of lactose synthase, which is an enzyme that catalyzes the synthesis of lactose from glucose. 4A4DG is an azide analogue of D-glucose and acts as an acceptor substrate for the enzyme. It has been found to be crystalline in nature and is composed of a monosaccharide. 4A4DG has been used in syntheses of several analogues of D-glucose and can be used as a potential inhibitor for lactose synthase.

<p>5-Ketomannose is a catalytic α-d-mannopyranoside that is used as a glycosidase inhibitor. It binds to the active site of glycosidases, blocking their activity and inhibiting the breakdown of carbohydrates. 5-Ketomannose has been shown to inhibit the action of a number of enzyme types, including glycosidases, glycoprocessing enzymes, and catalytic hydrogenation. This compound also inhibits deoxymannojirimycin, which is an inhibitor of glycosidase. 5-Ketomannose has anti-inflammatory effects and may be useful for treatment in inflammatory bowel disease (IBD) or ulcerative colitis.</p>

Insulinotropic; anti-diabetic

<p>Phenylethyl b-D-galactopyranoside is a galactose compound that can be hydrolyzed by esterases in the presence of water. It is toxic to organisms, such as E. coli and S. typhimurium, at high concentrations and can be used for the treatment of infections caused by these bacteria. Phenylethyl b-D-galactopyranoside has been shown to have a permeability effect on cells, which may be due to its ability to inhibit the production of ATP in the cell membrane by blocking specific enzymes that are responsible for ATP synthesis.</p>

<p>Decyl b-D-glucopyranoside is a cationic surfactant, which inhibits bacterial growth by disrupting the lipid bilayer of the cell membrane. It has been used as an antimicrobial agent in the treatment of autoimmune diseases and as a preservative in cosmetics. Decyl b-D-glucopyranoside has also been shown to be effective against citric acid and sodium citrate, two common components of biofilm formation. Decyl b-D-glucopyranoside has chemical stability in both acidic and alkaline environments and is not affected by pH levels. It is also a fatty acid with a hydroxyl group and an ethylene diamine side chain.</p>

<p>Difucosyllacto-N-tetraose is a lacto-n-fucopentaose that has been shown to be secreted by human milk. The index of this oligosaccharide is not significantly different between breastfed and formula-fed infants, which indicates that it is not influenced by the type of infant feed. Difucosyllacto-N-tetraose can be used as a marker for the frequency of infections in neonates and infants, because its levels are decreased in cases of infection. This oligosaccharide is also related to the diversity of oligosaccharides in colostrum, as it is one component of a subset found only in colostrum samples from healthy mothers.</p>

2,3,5,6-Tetra-O-trimethylsilyl-D-glucono-1,4-lactone is a monosaccharide that has been modified with trimethylsilyl groups. This modification protects the molecule from undesired degradation and enables various chemical reactions to be performed. 2,3,5,6-Tetra-O-trimethylsilyl-D-glucono-1,4-lactone can be used as an intermediate in the synthesis of oligosaccharides and polysaccharides. It can also be used to modify saccharides by fluorination or methylation.

Fructosyl-lysine is a substituted lysine that is formed through the glycation of proteins by sugars. It can be detected by fluorescence spectrometry and has been shown to inhibit the activity of receptor tyrosine kinases, which are involved in physiological functions such as cell growth and differentiation. Fructosyl-lysine also inhibits collagen synthesis and reduces the amount of glucose in human serum. This compound may be used as a model system to study glycation reactions with lysine, fatty acids, and other amino acids. The concentration of fructosyl-lysine found in human serum is at physiological levels and may not have any effect on antibody response.

<p>6-Deoxy-2,3:4,5-di-O-isopropylidene-L-glucose is a methylated sugar that is custom synthesized for research purposes. It is an oligosaccharide with a polysaccharide backbone. 6DG has been modified with fluorination and the Click reaction to produce novel compounds. The compound has been shown to have various biological activities, including anti-inflammatory effects. 6DG is a sugar with a complex carbohydrate structure that can be used in synthetic chemistry for modification and modification reactions.</p>

UDP-α-L-rhamnose sodium is a non-invasive prenatal diagnosis (NIPD) technique that detects the chorionic villus sampling (CVS) or amniocentesis samples of women. It is an in vivo assay that can be performed on pregnant women at any gestational age. The test is based on the detection of the uptake of UDP-α-L-rhamnose by cells, and it accommodates a wide range of sample types. The procedure is rapid, inexpensive, and highly accurate. Furthermore, it can be used as a screening tool for certain genetic disorders such as Down syndrome and Klinefelter syndrome.

<p>5-Deoxy-5-dimethylamino-1,2-O-isopropylidene-a-D-xylofuranose is a fluorinated monosaccharide that is used as a synthetic building block for the synthesis of oligosaccharides and polysaccharides. It is used in glycosylation reactions to introduce fluoride at the anomeric carbon. 5-Deoxy-5-dimethylamino-1,2-O-isopropylidene is also used in click modification reactions to modify methyl groups. The CAS number for 5DDAIWF is 14514743. 9. This product has high purity with a purity of greater than 99%.</p>

<p>The 1,6-anhydro-2-O-acetyl-3,4-dideoxy-b-D-erythrohexopyranose is a modified monosaccharide that has been fluorinated and methylated at the C1 position. This modification has shown to affect the susceptibility of bacteria to antibiotics. Fluorination and methylation at the C1 position of the sugar molecule can alter antibiotic binding affinity, which may be used as an alternative strategy for treating drug resistant bacterial infections.</p>

<p>3-O-(β-D-Galactopyranosyl)-D-glucopyranose is a custom synthesis, modification, and fluorination of a monosaccharide. It is a synthetic and modified saccharide. The molecular formula for this compound is C6H10O5 and its molecular weight is 180.17 g/mol. This chemical has been assigned CAS No. 28447-38-3 and has the following structure:</p>

This is a synthetic, fluorinated, monosaccharide. It has been custom synthesized and is available in high purity. This compound can be modified with additional functional groups to provide glycosylation or polysaccharides. The CAS number for this product is 538-37-0.

Perseitol is a nutrient solution that contains fatty acids and is used in tissue culture to supplement the growth of cells. It can be used as a substitute for animal serum, which is usually derived from bovine or porcine sources. Perseitol provides all essential components required for cell growth, including amino acids, vitamins, minerals, and lipids. Perseitol is also used in vitro assay systems to determine the redox potential of substances. This solution has been shown to have anti-inflammatory properties due to its ability to inhibit prostaglandin synthesis.

<p>2-Amino-2,6-dideoxy-L-mannose hydrochloride is a high purity and custom synthesis sugar. It is synthesized from 2,6-Dideoxymannose with the use of Click chemistry. This modification allows for a variety of fluorinations, glycosylations, and methylations to be used in the synthesis process. The CAS number for this compound is 107625-00-3.</p>

NA2F Glycan is a custom synthesis that is used in the identification and quantification of methylated polysaccharides. It is a synthetic modification of a natural glycosylation reaction. The NA2F Glycan is synthesized by 2-AB labelled Methylation, saccharide, Polysaccharide, CAS No., Click modification, Modification, Oligosaccharide, Custom synthesis, Glycosylation, High purity, Carbohydrate, sugar, Synthetic, Fluorination with high purity and complex carbohydrate. This product can be used in glycobiology research as a methylation-sensitive probe for the detection of methylated polysaccharides such as glycoproteins and glycolipids.

<p>5'-O-(2-Amino-2-deoxy-D-glucopyranosyl)-thymidine is a custom synthesis of saccharide that is fluorinated, methylated, and monosaccharide. This compound has been modified with a click modification and an oligosaccharide. The saccharide is glycosylated with sugar and Carbohydrate. 5'-O-(2-Amino-2-deoxy-D-glucopyranosyl)-thymidine has CAS No. 631842-24-5</p>

2,3,4-Tri-O-acetyl-D-ribononitrile is a modification of the sugar ribose. It is used as a building block for oligosaccharides and polysaccharides. This chemical can be custom synthesized by modifying the sugar ribose with acetyl groups on the 2, 3 and 4 positions. The acetyl group on the 2 position can be removed through methylation to give tri-O-methyl-D-ribononitrile.

Hyaluronic acid is a glycosaminoglycan found in many organs where it functions as a joint lubricant and shock absorber (Collins, 2006). It is obtained principally from synovial fluid, vitreous humor of the eye, umbilical tissue and cockscomb. The chemical structure of hyaluronic acid is a disaccharide repeat of β-1,3 glucuronic acid and β-1,4 N-acetyl glucosamine (Casu, 1990). Hyaluronic acid is a common ingredient in skin care products and is used as a dermal filler in cosmetic surgery.

<p>Chitotriose undecaacetate is a synthetic substrate that is used in transfecting experiments. It has high sensitivity and can be used to introduce nucleic acid into cells. Chitotriose undecaacetate is used as a synthetic fluorometric assay for the determination of chitinase activity in vitro or as a substrate for cell-free synthesis of nucleic acids. It has been shown to possess moieties that are sensitive to hydrogen chloride and chloride ions, making it an effective probe for the determination of these ions. Chitotriose undecaacetate also reacts with sephadex G-200, which makes it useful for separating DNA fragments by electrophoresis.</p>

Emodin 1-glucoside is a natural anthraquinone glycoside that is produced by plants and has been shown to have cytotoxic effects against human cells. Emodin 1-glucoside inhibits the function of enzymes, such as glycosidases, phosphatases, and proteases. This compound is activated by calcium ions and has been shown to disrupt mitochondrial membrane potential. Emodin 1-glucoside also inhibits sugar residues and has shown significant cytotoxicity against cultured human cells at higher concentrations. It may be used as a medicine for the treatment of inflammation or cancer.

<p>Methyl 2,3-di-O-benzyl-a-D-galactopyranoside is a fluorination reagent that can be used to introduce fluorine atoms in the sugar backbone of a carbohydrate. It has been used for the synthesis of complex carbohydrates and oligosaccharides. Methyl 2,3-di-O-benzyl-a-D-galactopyranoside can also be used to modify glycosylation or polysaccharide structures by methylating or chlorinating the sugar moiety. The chemical is available from various suppliers at different purity levels.</p>

<p>This beta-cyclodextrin (β-CD) derivative is a functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.</p>

<p>Chrysin-7-glucuronide is a metabolite of chrysin, which is found in the roots of Oroxylum indicum. This compound has been shown to inhibit the enzyme activity for multidrug resistance (MDR) and cancer resistance (CDR). It has been found that chrysin-7-glucuronide inhibits MDR and CDR in vitro by binding to the ATP binding site on these enzymes. Chrysin-7-glucuronide also inhibits the production of acid in vivo and in vitro, which may be due to its ability to inhibit cellular proliferation. Chrysin-7-glucuronide may be an effective anti-cancer agent when used as a dietary supplement.</p>

<p>Neutral disaccharide naturally present in human breast milk and possible bifidus factor, acceptor for the Helicobacter pylori enzyme α1,2-fucosyltransferase and disaccharide involved in the expression of Lewis blood group antigens.</p>

GM1 pentasaccharide (sodium salt) has a core tetrasaccharide structure (Galβ1,3GalNAcβ1,4Galβ1,4Glc) with a single sialic acid residue linked α2,3 to the inner galactose residue (Ledeen, 2009). GM1 pentasaccahride is the carbohydrate moiety of GM1 ganglioside. GM1 ganglioside interacts and modulates tyrosine kinases, such a,s neural tropomyosin receptor kinase A (TrkA), by inducing the release of neurotrophins from fibroblast cells and the epidermal growth factor receptor (EGFR) (Higuero, 2009). GM1 ganglioside is also found in epithelial membranes; it is a key element for bacterial toxicity and viral infection as it acts as a receptor for the B-subunits of heat-labile toxin, cholera toxin, rotavirus, and simian virus 40. GM1 ganglioside also has the ability to bind amyloid-β proteins and is involved in Alzheimer’s pathogenesis (Chiricozzi, 2020).

4-Aminobutyl 1,3-a-1,6-a-D-mannotriose is a custom synthesis that belongs to the category of oligosaccharides and polysaccharides. It is an aminotriose with a methyl group at the C4 position. The fluorinated glucose moiety and the 4-aminobutylic acid residue are in an alpha configuration. This oligosaccharide has been modified by click chemistry and features high purity. The modification was carried out by condensing the sugar with a boronic acid and then reacting this with an azide group. The resulting product is then reacted with a maleimide to create a conjugate that can be used in bioconjugation reactions.

Dodecyl a-D-thiomannopyranoside is a glycosylation reagent that has been used in the synthesis of complex carbohydrates, polysaccharides, and oligosaccharides. It is a methylated thioglycoside that can be used for click modification. Dodecyl a-D-thiomannopyranoside is an excellent fluorinating agent for saccharides and sugars, which can be accomplished using sodium hypofluorite. Dodecyl a-D-thiomannopyranoside is also an excellent monosaccharide synthesizer and custom synthesiser. This compound has CAS number 95734-05-1 and can be ordered at very high purity from various chemical suppliers.

Versatile resource for organic synthesis, e.g. of the inhibitor swainsonine

Benzocaine N-b-D-glucoside is an adjuvant that is used in pharmaceutical products. It has been shown to increase the stability of drugs and prolong their effects. Benzocaine N-b-D-glucoside also enhances the absorption, distribution, and elimination of drugs. This adjuvant has a number of functionalities including being a carbonyl scavenger and having mottling effects on drug particles. Benzocaine N-b-D-glucoside is often used as a pharmaceutical product adjuvant to stabilize formulations and extend the shelf life of medications.

O-(2,2',3,3',4',6,6'-Hepta-O-acetyl-b-D-maltosyl)-N-hydroxysuccinimide is a methylating reagent that is used in the synthesis of glycosides. It can be used to modify saccharides and polysaccharides with the desired sugar moiety.

Phenyl 2,3,4-tri-O-benzyl-b-L-thiofucopyranose is a synthetic monosaccharide that is modified with fluorine. It is also known as 3,4,6-tri-O-benzyl-2,3,4,6-tetra-O-(trifluoromethyl) fucopyranose. This compound is a complex carbohydrate that belongs to the group of glycoconjugates and polysaccharides. Phenyl 2,3,4-tri-O-benzyl-b-L-thiofucopyranose has been shown to be useful in glycosylation reactions as well as in click chemistry reactions. This compound can be used for the synthesis of oligosaccharides and polysaccharides with custom modifications. Phenyl 2,3,4 tri O benzyl b L thiof

3,4,6-Tri-O-acetyl-2-deoxy-2-fluoro-D-glucopyranosyl fluoride is a fluorine containing compound. It has been analyzed using spectroscopic techniques and found to be a white crystalline solid with an empirical formula of C12H14F3O11.

Chitosan oligomer (Dp 12-20) is a modification of chitin, a polysaccharide. It can be synthesized by treating chitin with sodium hydroxide in an alkaline environment. Chitosan oligomer (Dp 12-20) has a high degree of saccharide modification and exhibits a variety of functions, including complex carbohydrate, custom synthesis, synthetic, high purity, CAS No., and monosaccharide methylation. This compound has been shown to inhibit the growth of bacteria such as Staphylococcus aureus and Clostridium perfringens.

<p>4-O-(b-D-Ribofuranosyl)-L-rhamnopyranose is a custom synthesized monosaccharide that can be modified with fluorination and methylation. This sugar can be used for glycosylation reactions to form oligosaccharides or polysaccharides. The number of sugar molecules that are attached to the sugar determines the complexity of the carbohydrate. 4-O-(b-D-Ribofuranosyl)-L-rhamnopyranose is an example of a complex carbohydrate because it has four sugars attached to it.</p>

<p>1,2:5,6-Di-O-isopropylidene-D-mannitol is an organic compound that belongs to the group of mesoporous materials. It has a high surface area and is capable of absorbing large amounts of water. 1,2:5,6-Di-O-isopropylidene-D-mannitol has been shown to be able to absorb chloride ions in acidic environments due to its acidic hydrolysis properties. The water that is absorbed by this material can then be released when the solution becomes neutral again. This material can also act as a proton sponge and may have applications in the treatment of acid mine drainage or other industrial pollution. 1,2:5,6-Di-O-isopropylidene-D-mannitol may be used for chromatography techniques such as gas chromatography and liquid chromatography due to its functional groups that are sensitive to changes in pH levels.</p>

Trivalent GalNAc precursor

<p>1,4-Anhydro-6-chloro-6-deoxy-D-glucitol is a complex carbohydrate that has been fluorinated and modified with methyl groups. It can be custom synthesized to produce high purity compounds. 1,4-Anhydro-6-chloro-6-deoxy-D-glucitol is used in synthesis of saccharides and oligosaccharides. The compound has been modified with Click chemistry to produce glycosylation products. It can also be used as an intermediate for the synthesis of sugar derivatives.<br>1,4-Anhydro-6-chloro-6-deoxy--D--glucitol has the following chemical structure:</p>

4-Aminophenyl β-D-thiogalactopyranoside is a custom synthesis of a fluorinated saccharide. It is an oligosaccharide that has been modified with a click modification, which is an atom transfer radical polymerization. The chemical name for 4-aminophenyl β-D-thiogalactopyranoside is 2,5-difluorobenzoyl-(1→4)-4-(4'-aminophenoxy)butyryl-(1→2)-β-D-thiogalactopyranoside. The CAS number for 4-aminophenyl β-D-thiogalactopyranoside is 29558-05-2. This product has high purity and can be used as a substitute for saccharides in the synthesis of polysaccharides or oligosaccharides.

<p>4-Penten-1-yl 2,3,4,6-tetra-O-acetyl-b-D-glucopyranoside is a carbohydrate that is synthesized by the modification of an existing molecule. It is a custom synthesis and can be modified with click chemistry to create new compounds. This compound has a high purity and is soluble in water. It can be used for saccharide or polysaccharide synthesis as well as glycosylation reactions. This product's CAS number is 50256-33-2 and it has been assigned the chemical name Methylation, saccharide, Polysaccharide, Click modification, CAS No. 50256-33-2, Modification, Oligosaccharide, Custom synthesis, Glycosylation, High purity, Carbohydrate, sugar, Synthetic, Fluorination.</p>

<p>7-Deoxy-1,2-O-isopropylidene-L-glycero-a-D-glucoheptofuranose is a custom synthesis that is used in the modification of polysaccharides. It is fluorinated and methylated to make it more stable to hydrolysis. The Oligosaccharide, saccharide, CAS No., Polysaccharide, Glycosylation, sugar, Carbohydrate, complex carbohydrate are all modified with 7DG to form a new product.</p>

6-Deoxy-a-D-talose is a non-reducing sugar. It is used in the synthesis of glycosides and polysaccharides. 6-Deoxy-a-D-talose is hydrolyzed by esterases or glucuronidases, oxidized by cytochrome P450 enzymes, reduced by glutathione reductase, or conjugated with glucuronic acid.

Methyl 4-O-methyl-α-D-glucopyranoside is a methyl glucoside analogue

<p>L-Ribose-5-phosphate disodium salt hydrate is a carbohydrate that has been modified by the addition of fluorine. L-Ribose-5-phosphate disodium salt hydrate can be used in the synthesis of complex carbohydrates, oligosaccharides, and sugars. It is also used in the synthesis of glycoconjugates and glycoproteins. L-Ribose-5-phosphate disodium salt hydrate is available for custom synthesis to meet specific requirements. The purity level is high, with less than 0.1% impurities. The methylation, glycosylation, and click modification are all possible modifications for this product.</p>

Taxol is a natural product that is isolated from the bark of the Pacific Yew tree. It has been found to have antitumor activity against human and murine sarcoma, as well as human cancer cell lines. Taxol has been shown to inhibit the growth of cancer cells by binding to the β-subunit of tubulin, preventing polymerization into microtubules and therefore affecting mitosis. Taxol also inhibits glucose uptake and utilization by cancer cells, which may in part account for its anti-tumor activity. Taxol also contains galloyl groups that are responsible for its antifungal activity.

<p>Cerebrosides are a group of complex carbohydrates that have been modified by glycosylation, methylation, and/or fluorination. These modifications can be used to produce saccharides with different properties. Cerebrosides are found in the brain, central nervous system, and spinal cord. They are also found in the connective tissue of skin and hair follicles.<br>The CAS number for cerebrosides is 85116-74-1.</p>

Intermediate in the synthesis of dapagliflozin

<p>Allyl a-D-glucopyranoside is a trisaccharide with the chemical formula CHO. It is an important monomer in the synthesis of polymers that are used in, for example, textiles, construction materials, and plastics. Allyl a-D-glucopyranoside has been found to have optical properties that are similar to those of natural rubber. When irradiated with UV light, it undergoes photoinduced polymerization and has been shown to be hydrophilic. The hydrophilicity can be increased by adding alkali metal ions or metal cations such as polyphosphates or calcium ions. Allyl a-D-glucopyranoside also has immunoregulatory activities and can stimulate lymphocyte proliferation, antibody production, and macrophage activity.</p>

Inhibitor of sphingosine-1-phosphate lyase; immunosuppressant

<p>Allyl 2,3,4-tri-O-benzyl-a-D-glucopyranoside is a sugar that is used in the synthesis of glycosides. It can be synthesized by a click modification reaction that yields an allyl ether from an allylic alcohol. This product has been shown to react with bromine in the presence of UV light and produce a monobenzylated product, which can be used as a fluorescent probe for labeling saccharides. Allyl 2,3,4-tri-O-benzyl-a-D-glucopyranoside can also be modified with methyl groups or glycosidic bonds to form complex carbohydrates.</p>

<p>2-Acetamido-1,3,4,6-tetra-O-acetyl-2-deoxy-b-D-mannopyranose is a synthetic carbohydrate. It is a modified form of the natural sugar mannose that has been fluorinated. This modification gives 2-Acetamido-1,3,4,6-tetra-O-acetyl-2-deoxy--b--D--mannopyranose an increased resistance to degradation by enzymes. The CAS number for this compound is 6730–10–5.</p>

<p>1,5-Anhydro-2,3,4-tri-O-benzoyl-D-threo-pent-1-enitol is a high purity compound that is synthesized from D-threo pent 1 enitol. It is a sugar that belongs to the category of complex carbohydrates. This product can be custom synthesized and modified according to customer requirements.</p>

Used for structural and conformational studies and as enzyme substrates

<p>Component of plant, especially grape, glucuronoxylans</p>

<p>Bulk sweetener; viscosity/bodying agent; humectant; cryoprotectant</p>

<p>6-Deoxy-6-fluoro-D-galactose is a fluorinated sugar that has been shown to inhibit the uptake of glucose by human liver cells. This sugar binds to the enzyme activity and inhibits its activity. 6-Deoxy-6-fluoro-D-galactose was found to be metabolized in a dose dependent manner, with higher doses leading to increased uptake of fluorescein and decreased uptake of glucose. 6FDG is also metabolized by chemical reactions, such as oxidation or hydration, which leads to a decrease in its inhibitory effect on glucose uptake. 6FDG has been shown to bind to sequences that are involved in sugar transport and cell culture studies have shown that this sugar can induce inhibition of cell growth at high concentrations.</p>

A fucan sulphate found in brown marine algae (Phaeophyta-typically Fucus serratus, Ascophyllum nodosum, Laminaria japonica (illustrated) and Macrocystis pyrifyra) and has been shown to have anticoagulant activity. The main constituents are α-1,4 and α-1,2 linked L-fucose sulphates although galactose also occurs and there are many variations of the basic structure found in different species of Phaeophyta. The image was kindly provided by Prof Mike Guiry from Cork who runs ‘The Seaweed Site’.

<p>Chondroitin sulphate octasaccharide ammonium salt is a synthetic, fluorinated glycosaminoglycan. It is a synthetic, fluorinated glycosaminoglycan that has been synthesized from chondroitin sulfate and 2-amino-2-deoxy-D-glucose. Chondroitin sulphate octasaccharide ammonium salt has the CAS number 93860-92-7. It can be modified to make it more complex, such as methylation or click modification to give it different properties. This product is offered in high purity with a custom synthesis service available on request.</p>

<p>Methyl 2,3-di-O-acetyl-4,6-O-(4-methoxybenzylidene)-a-D-glucopyranoside is a synthetic saccharide that has been modified with methylation and fluorination. It is an oligosaccharide derived from glucose that can be obtained through the custom synthesis of a polysaccharide. This product has CAS No. 52526-77-9 and is available in high purity. It can be used for the modification of monosaccharides or other carbohydrates.</p>

3,4,6-Trideoxy-3-(dimethylamino-b-D-xylo-hexopyranose) is a carbohydrate that belongs to the group of saccharides. It is a sugar that has been modified with fluorine groups. Fluorination increases the hydrophilicity of the sugar and makes it more soluble in water. 3,4,6-Trideoxy-3-(dimethylamino-b-D-xylo-hexopyranose) has been custom synthesized and can be ordered as a high purity material. The synthesis process includes methylation and glycosylation steps. 3,4,6-Trideoxy-3-(dimethylamino-b-D-xylo -hexopyranose) is used as a click modification for proteins.

<p>D-Glucose is a sugar that is used in the production of polysaccharides and glycosylations. It can be modified with fluorination, saccharide methylation, or glycosylation. D-Glucose can be synthesized by the custom synthesis of an oligosaccharide. This product has high purity, and is both monosaccharide and complex carbohydrate.</p>

<p>1,2-Di-O-acetyl-3,5-di-O-benzoyl-3-b-C-methyl-D-ribofuranose is a fluorinated monosaccharide that is synthesized by the glycosylation of 2,6 anhydrofructose with benzaldehyde and acetone. It has a CAS number of 22672-43-1. This product can be used in the modification of polysaccharides or as a synthetic glycoside. It can also be used for click chemistry modification of sugars or as a high purity custom synthesis.</p>

<p>1,2,3,6-Tetra-O-acetyl-a-D-glucopyranose is a high purity chemical that can be custom synthesized. It is a sugar that has been fluorinated and glycosylated with a Click modification. It is a synthetic compound that contains methylation and modification. It has CAS No. 55286-97-0, which indicates its oligosaccharide and monosaccharide saccharide composition. This product can be used for complex carbohydrate synthesis in the laboratory or for research purposes.</p>

<p>1,4-Dideoxy-1,4-imino-D-ribitol is a polyhydroxylated pyrrolidine alkaloid isolated from the roots of mulberry trees (Morus alba) and from the bark of leguminous plants (Angylocalyx pynaertii).  Due to its structure it has been looked at as enzyme inhibitors that mimic glycoside and nucleoside substrates.  It was found to be a potent inhibitor of lysosomal β-mannosidase and eukaryotic DNA polymerases.</p>

2,3,6,2',3',6',2'',3'',4'',6''-Deca-O-acetyl-a-D-maltotriosyl bromide is an acetylated and fluorinated oligosaccharide that has been prepared by a click reaction. It can be used for the synthesis of glycosidic linkages in complex carbohydrates. This product is available as a custom synthesis.

<p>Colchicoside is a natural compound that belongs to the chemical family of phenylpropanoids. It is used in the treatment of gout and pseudogout, and has been shown to be effective against demecolcine-induced hemolytic activity. Colchicoside has also shown to be an analog for other compounds with toxicological studies, such as hydrochloric acid and potassium dichromate. The toxicity studies performed on colchicoside have shown that it can cause damage to cells in culture by inhibiting DNA repair mechanisms.</p>

Octyl β-D-galactopyranoside is a chemosensor that has been used to detect the presence of aldehydes. The transfer mechanism of octyl β-D-galactopyranoside involves micelles, which are aggregates of amphiphilic molecules that form spherical structures in water. Octyl β-D-galactopyranoside has been shown to have antibacterial activity against gram-positive bacteria and leishmania parasites. This compound is also used as a glycosidase inhibitor, which prevents the breakdown of carbohydrates by enzymes called glycosidases. It is believed that this inhibition occurs because octyl β-D-galactopyranoside binds to the active site of the enzyme, thereby preventing access by the substrate. The optimum temperature for octyl β-D-galactopyranoside's activity is between 20 and 25 degrees Celsius. Octyl β-D-galactopyranoside

3,6-Di-O-methyl-D-glucose is a glycopeptide sugar that is used as a terminal sugar in the cell wall of many gram-positive bacteria. It is found on the surface of most strains of Streptococcus pneumoniae and Staphylococcus aureus. 3,6-Di-O-methyl-D-glucose is an antigen for monoclonal antibodies against the streptococcal M protein and has been used to identify the carbohydrate chemistry of Streptococcus pneumoniae. 3,6-Di-O-methyl glucose may also be useful in the detection of cellulose derivatives by magnetic resonance spectroscopy or nitrocellulose membranes. The terminal sugars found on these membranes are hydrolyzed by acid and dry weight methods before being analyzed by gas chromatography or high performance liquid chromatography.

<p>N-Acetyl-D-glucosaminitol is a fatty acid that is found in blood group antigens. It has been shown to be a potent inhibitor of human liver serine proteases, with an IC50 of 10 μM and a Ki value of 1.6 μM. N-Acetyl-D-glucosaminitol also inhibits the terminal steps in glycolysis and can be used as a substrate for glycosidases. It is capable of forming oligosaccharides with terminal residues and can be analyzed using titration calorimetry. The molecular weight of N-acetyl-D-glucosaminitol is calculated to be 398 Da by nmr spectroscopy. Structural analysis shows that this compound contains monoclonal antibodies and sugar residues, which are important for its function.</p>

<p>1-Deoxy-3-O-tert.butyldimethylsilyl -4,5-O-isopropylidene -D-fructose is a glycosylation reagent used to modify the carbohydrate moieties of proteins and other molecules. It reacts with a protein to produce an alpha O-linked glycosylation at the N terminus of the protein. 1DOTBSDF can be prepared by reacting 1,3,5,7-tetraacetylbenzene with methyl methanolate in the presence of butyllithium. The product is purified by crystallization from hexane and diethylether and has a melting point range of 114°C – 117°C. This compound has been reported in the literature as being used for Click modification reactions that have been reported to have improved yields in comparison to other methods.</p>

3-O-Benzyl-1,2-O-isopropylidene-6-O-trityl-a-D-glucofuranose is a synthetic oligosaccharide. It is a glycosylation product of the 6′ position of β-(3,4-)dihydroxybenzoyl α-(1,6)-Dglucopyranosyl bromide with 3,5,-O-(tetraisopropyldisiloxanyl) benzyl alcohol. The molecular weight is 588.8 g/mol and it has the molecular formula C28H31NO14. 3BBIG is soluble in water and methanol, but insoluble in ethanol or ether. This compound can be used for methylation reactions or click chemistry modifications.

4-Methoxyphenyl 4-O-(2,4,6-tri-O-acetyl-3-O-allyl-b-D-galactopyranosyl)-3-O-allyl-b-Dglucopyranoside is a synthetic sugar with a molecular weight of 532. This product can be used in the synthesis of oligosaccharides and monosaccharides. It is also used as an intermediate in glycosylation reactions. This product has not been assigned a CAS number yet.

<p>3-Deoxy-3-fluoro-1,2-O-isopropylidene-D-allofuranose is an oligosaccharide that has been fluorinated at the 3 position and 3' position of the allofuranose moiety. It is a synthetic monosaccharide that belongs to a family of complex carbohydrates. The modification of this sugar with fluorine atoms is done by click chemistry, which entails the use of copper (II) ions. This sugar can be used for glycosylation and polysaccharide synthesis. Its high purity makes it ideal for use in laboratory settings.</p>

3,6-Dideoxy-3,6-imino-1,2-O-isopropylidene-a-D-glucofuranose is an oligosaccharide that has been modified to contain fluorine. This sugar is a complex carbohydrate that can be custom synthesized for use in glycosylation reactions. It can be used to modify polysaccharides and has been shown to have a high purity.

5-Azido-5-deoxy-2,3-O-isopropylidene-L-lyxofuranose (AIL) is a synthetic molecule that belongs to the group of carbohydrates. It is synthesized by the glycosylation and methylation of 5-(azido)-5,6-dideoxyglucose. AIL has been shown to have anti-inflammatory effects in cell culture models and in mice with inflammatory bowel disease.

2-Deoxy-L-ribose-anilide is a chemical compound that has been patented for its use in the detection of magnetic fields. The patent claims that this compound can be used as an intermediate in the preparation of other compounds. 2DRA has different transition temperatures, depending on whether it is in the solid or liquid state. When 2DRA is heated, it changes from a colorless liquid to a yellow crystal at around 100°C and then becomes a white solid at around 150°C. The magnetic properties of 2DRA arise from its ability to form strong bonds with other molecules, which are broken by external magnetic fields.

<p>Derived from pullulan using pullulanase</p>

Benzyl 2-acetamido-2-deoxy-4,6-O-isopropylidene-b-D-glucopyranoside is a surfactant that is used in the measurement of polymers. It is soluble in water and has a low concentration. This surfactant can be used as a copolymer with terephthalate to form polyurethane foam. Benzyl 2-acetamido-2-deoxy-4,6-O-isopropylidene b -D -glucopyranoside also has high concentrations for sedimentation and sulfonate properties.

Synthetic building block

<p>2-O-Benzhydryloxybis(trimethylsilyloxy)silyl-3,4-O-isopropylidene -L-arabinonic acid gamma-lactone (2BHOS) is an oligosaccharide that is synthesized from arabinose. It is a product of the Click modification and is used to synthesize a glycosylation with a monosaccharide or saccharide donor molecule. 2BHOS can be modified by fluorination, glycosylation, methylation, or other chemical modifications. 2BHOS has CAS number 47311-27-8.</p>

(1R) -1- [(2S, 3R,4S) -4-Hydroxymethyl-3- hydroxy- 1- azetidinyl] -1, 2- ethanediol hydrochloride is a synthetic modification of oligosaccharides and polysaccharides. It is an oligosaccharide with a high degree of polymerization (DP) and a high purity. The fluorination of saccharides can be used for the synthesis of this product.

<p>Methyl 2,3,4-tri-O-benzyl-6-O-tert-butyldimethylsilyl-a-D-galactopyranoside is a fluorinated monosaccharide that is used as a building block for the synthesis of oligosaccharides and polysaccharides. This chemical has been modified with methylation and click chemistry to give it an interesting utility in glycosylation reactions. Methyl 2,3,4-tri-O-benzyl-6-O-tert butyldimethylsilyl -a D galactopyranoside has a CAS number of 862730 60 7. It is soluble in methanol and ethanol and can be purified by recrystallization or chromatography. It has been shown to be nonmutagenic and nontoxic.</p>

Methyl 3-O-(a-D-mannopyranosyl)-b-D-mannopyranoside is a custom synthesized compound that belongs to the group of complex carbohydrates. It is used in the synthesis of oligosaccharides and polysaccharides. Methyl 3-O-(a-D-mannopyranosyl)-b-D-mannopyranoside can be modified through fluorination, which enhances its properties. This product is available in high purity and with a monosaccharide content of 99%. The CAS number for this compound is 4127757-76-4.

<p>3,6-Anhydro-D-galactose is a monosaccharide of D-galactose where the 3 and 6 positions are cyclised in an ether link. 3,6-Anhydro-D-galactose is found naturally occurring in Rhodophyta (Red Algae) and is a constituent of the sulphated polysaccharide PLS, which has shown anti-inflammation activity and anti-nociceptive effects. In addition, sulphated polysaccharide is capable of inhibiting the in vitro replication of Herpes simplex virus type 1 (HSV-1) and HIV-1.<br>We also offer this product in 10% aqueous solution (MA07897).</p>

<p>2-Acetamido-2-deoxy-5-thio-D-glucose is a custom synthesis product. It is an oligosaccharide or polysaccharide that is modified with a fluorine atom in the 2 position of the sugar. This modification can be done either by Click chemistry or by chemical oxidation. The modification of 2-acetamido-2-deoxy-5-thio-D-glucose makes it useful as a fluorescence probe for probes and as a fluorescent dye.</p>

<p>Hexahydro-1,2,8-trihydroxy-[1S-(1a,2a,8a,8ab)]-5(1H)-indolizinone is a custom synthesis of a complex carbohydrate. It is an Oligosaccharide and Polysaccharide. The saccharide Methylation and Glycosylation are the Modification of this molecule. This product has CAS No. 96625-36-4 and Click modification is Carbohydrate sugar. This product is highly pure with Fluorination Synthetic</p>

Component of glycoproteins and glycolipids expressed in antigens and receptors of proteins, bacteria and viruses. Found in the free form in human biofluids, including urine and milk - preventing adhesion of bacteria to urinary epithelium and inhibiting enteric pathogens respectively. An efficient inhibitor of neutrophil-activating protein of H.pylori (HPNAP)-mediated neutrophil activation.

<p>N-(Phenyl-2-methyl-1-propenyl)imino-2,3,4,6-tetra-O-pivaloyl-D-glucopyranoside is an Oligosaccharide that contains a sugar. It has been custom synthesized for the purpose of fluorination and methylation reactions. The purity of this product is high and it has been assigned the CAS number: 3642.</p>

<p>Dextran is a polysaccharide that is used as an antimicrobial agent and as a volume expander in the treatment of bowel disease, myocardial infarct, and other diseases. Dextran sulfate is a linear polymer with a molecular weight of 500,000 to 1,000,000. It has minimal toxicity and does not interfere with iron homeostasis or cause fluid overload. Dextran sulfate can be used for the treatment of bowel disease because it has been shown to have anti-inflammatory effects in experimental models. The mechanism by which dextran sulfate inhibits inflammation is unknown, but may involve its ability to bind to macrophages and neutrophils in the gut wall. Dextran sulfate also binds to bacteria and prevents their growth. This binding may prevent bacterial penetration into epithelial cells or block bacterial attachment to cell surfaces. The efficacy of dextran sulfate against pathogenic mechanisms such as inflammation has been demonstrated in experimental models.</p>

<p>1-Bromo-2,3,4-tri-O-acetyl-a-D-glucuronide methyl ester is a protected D-glucoronic acid with an alpha bromide at the anomeric position ready to undergo glycosylation reactions with suitable glycoside acceptors. Pharmaceutically active compounds have been used as acceptors to form β-linked D-glucuronide prodrugs which can be used to modify pharmacokinetics, improve solubility and lower the toxicity of the drug.</p>