Glycoscience

<p>1,4-Anhydro-2,O:5,6-di-O-isopropylidene-2-C-(hydroxymethyl)-D-galactitol is a custom synthesis. It is commonly used in the modification of saccharides and oligosaccharides to produce fluorinated derivatives with various functional groups. The preparation of this compound has been described by Click chemistry.</p>

<p>Inhibits the Maillard reaction between glucose and glycine</p>

<p>N-Acetyl D-mannosamine (ManNAc) is an aldohexose (2-acetamido-2-deoxymannose) in which the axial hydroxyl group at position 2 is replaced by a N-acetyl group (Collins, 2006). It has been reported that N-acetyl D-mannosamine supplementation, may provide novel means to break the link between obesity and hypertension (Peng, 2019). N-Acetyl-D-mannosamine and N-acetyl-D-glucosamine are the essential precursors of sialic acid, the specific monomer of polysialic acid, a bacterial pathogenic determinant, for example, Escherichia coli K1 uses both amino sugars as carbon sources. It has been reported that ManNAc can be used as a treatment for hereditary inclusion body myopathy, an adult-onset, progressive neuromuscular disorder and also for renal disorders involving proteinuria and hematuria due to podocytopathy and/or segmental splitting of the glomerular basement membrane (Galeano, 2007).</p>

<p>D-Allose pentaacetate is a modified oligosaccharide that can be used as a synthetic intermediate in the production of complex carbohydrates. It has been shown to have high purity and is easily synthesized in a laboratory setting. D-Allose pentaacetate is a monosaccharide with five acetate groups that can be methylated or glycosylated, which makes it an ideal candidate for modification. D-Allose pentaacetate has CAS No. 144071-49-8 and can be found on PubChem CID: 1215965.</p>

<p>1-Azido-1-deoxy-2-C-hydroxymethyl-2,3-O-isopropylidene -D-glucitol is a synthetic monosaccharide that can be used for glycosylation, methylation, and click modification. It is a complex carbohydrate with an Oligosaccharide structure. 1-Azido -1-deoxy -2 -C -hydroxymethyl -2,3 -O -isopropylidene D glucitol has been fluorinated. This compound is a sugar that has been modified with a Click modification. It is a sugar that has been synthesized and custom synthesized by high purity.</p>

<p>Ethyl 2-O-benzoyl-3-O-benzyl-4-O-levulinoyl-b-D-thioglucopyranoside is a glycosylation product of ethyl levulinate and 3,4,6,7,8,9,10,11,12-hexahydroxybenzoate. This compound has undergone methylation at the C2 position of the benzoic acid moiety and click modification at the C1 position of the benzoyl group. It is a polysaccharide that is used as a fluorinating agent in organic synthesis. Ethyl 2-O-benzoyl-3-O-benzyl-4-O-levulinoyl b -D--thioglucopyranoside is an oligosaccharide with six monosaccharides attached to each other by glycosidic bonds. The CAS No</p>

<p>3-Deoxy-D-gluconic acid is a chemical compound that has the chemical structure of C6H12O6. It is a white crystalline solid that can be found in nature as a reaction product of glucose and oxygen. 3-Deoxy-D-gluconic acid can also be synthesized by reacting D-glucose with nitrous acid or sulfur dioxide. 3-Deoxy-D-gluconic acid is an organic acid and has been shown to inhibit the growth of filamentous fungi by acting on their glycosidic bonds. This chemical compound has not been shown to have any adverse health effects in humans, although it may cause irritation if it comes into contact with skin or eyes.</p>

<p>1-O-Methyl-β-D-glucuronic acid is a β-glucuronidase inducer.</p>

<p>This molecule contains three terminal beta-N-acetylgalactosamine (GalNAc) sugars for efficient ASGPR binding. The beta-alanine linker separates the GalNAc unit from a PEG3 spacer, improving water solubility and potentially influencing pharmacokinetics. The terminal amine group serves as a reactive handle for conjugation to various biomolecules via amide bond formation. This multifunctional combination makes tri-b-GalNAc-b-alanine-PEG3-amine a versatile tool for researchers developing targeted therapies and diagnostics exploiting the ASGPR pathway.</p>

<p>1-Hydroxymethyl-8-benzyloxy-3-methoxy-2,6-dioxabicyclo[3,2,1]octane is a sugar that can be modified with various functional groups. This compound is synthesized by modification of the 1S,3S,4R,8S configuration of 8-Benzyloxy-1-(hydroxymethyl)-3-methoxy-2,6 dioxabicyclo[3,2,1]octane. The synthesis can be performed in two steps: first the hydroxymethyl group is replaced by benzyloxymethyl using 1-(benzyloxy)propanol and then the methoxy group is replaced by a methoxy group with sodium methoxide.</p>

<p>Potential prebiotic oligosaccharides made from agar by enzymatic hydrolysis</p>

<p>Dextran sulfate sodium salt is a water-soluble polymer that is used as a drug carrier and has many applications in the pharmaceutical industry. It is an oligosaccharide with an average molecular weight of 9,000 to 16,000 Daltons. Dextran sulfate sodium salt can be used for the treatment of cavities, especially those that are infected or in which there is a risk of infection. It can also be used for intubation and has been shown to be effective at reducing allergic reactions by blocking the release of histamine by mast cells. Dextran sulfate sodium salt also has kinetic properties and can be used to study enzymatic reactions. This polymer is not toxic because it cannot be absorbed through the skin or gastrointestinal tract.</p>

<p>1-Deoxy-L-allitol is a naturally occurring compound found in human urine. It has been shown to have a role in the regulation of glucose metabolism, as it is catalysed by liver enzymes and can affect the synthesis of glycogen. 1-Deoxy-L-allitol also has been found to be an activator of t-cells, which are immune cells that help regulate the body's response to infection.</p>

<p>2-Deoxy-4-C-methyl-2-methylene-3,4-O-isopropylidene -L-erythro pentonic acid d-lactone is a methylated sugar with a degree of substitution of 1.0, which can be used for the synthesis of various saccharides and polysaccharides. This product has been modified with click chemistry. It is available in custom synthesis and high purity. The CAS number for this compound is 121592-71-8, and it can be used to synthesize glycans or oligosaccharides. This product can be fluorinated or complexed with other sugars.</p>

<p>Di-O-isopropylidene psicose is a synthetic sugar that is a modification of the natural compound, psicose. It can be used for the synthesis of oligosaccharides, polysaccharides and other complex carbohydrates. Di-O-isopropylidene psicose can be methylated and glycosylated to form other sugar derivatives or fluorinated to form fluoroquinolones. This sugar has been shown to have high purity and stability under a wide range of conditions.</p>

<p>(2S, 3R, 4R) -3-Benzyloxy-1-butyl-4-(hydroxymethyl)-N-methyl-2-azetidinecarboxylic acid methyl ester is a modification of an oligosaccharide. This product is custom synthesized and has a high purity. It is a methylated carbohydrate that contains a fluorinated saccharide.</p>

<p>Please enquire for more information about D-Fructose 1-phosphate disodium including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Reference compound for metabolites of the pentosephosphate pathway</p>

<p>Ribulose 5-phosphate sodium is a chemical that can be used to inhibit the enzyme ribulose phosphate reductase. Ribulose 5-phosphate sodium has been shown to inhibit glycolaldehyde production in the chloroplasts of plants, effectively reducing the amount of carbon dioxide produced. This chemical has also been shown to have an inhibitory effect on other enzymes involved in carbon fixation and assimilation. The effectiveness of this chemical is dependent on the specific plant species and environmental conditions.</p>

<p>This beta-cyclodextrin (β-CD) derivative is a functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.</p>

<p>In water, hydroxypropyl cellulose forms liquid crystals with many mesophases depending on concentration. These mesophases include isotropic, anisotropic, nematic and cholesteric, the latter resulting in many colors such as violet, green and red. Pharmaceutical applications include treatments for medical conditions such as dry eye syndrome (keratoconjunctivitis sicca), recurrent corneal erosions, decreased corneal sensitivity, exposure and neuroparalytic keratitis. It is also used as a binder in tablets. Hydroxypropylcellulose is also used as a thickener, a binder and emulsion stabiliser in foods with E number E463.  HPC is used as a support matrix for DNA separations by capillary and microchip electrophoresis.</p>

<p>Chondroitin disaccharide 6S sodium salt is a synthetic, fluorinated, oligosaccharide that has been custom synthesized and glycosylated. It is a sugar-based compound with a high purity and excellent solubility in water. It was synthesized by click modification of the sugar monomer with an amine group at the reducing end. The chondroitin disaccharide 6S sodium salt was further modified with methylation to yield a product with a higher purity.</p>

<p>Applications N,N-[Iminobis(trimethylene)]bis-D-gluconamide (cas# 86303-20-0) is a compound useful in organic synthesis.<br></p>

<p>Please enquire for more information about D-Xylose-1-C-D including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-Deoxy-D-glucose is a sugar that is synthesized by the condensation of two molecules of erythrose. It has been shown to be an efficient donor substrate for nucleophilic attack, which can lead to the synthesis of glycosides and other natural products. 4-Deoxy-D-glucose is also a competitive inhibitor of uridine diphosphate (UDP) glucose, which is an enzyme involved in the biosynthesis of UDP sugars and glycoproteins. The concentration of 4-deoxy-D-glucose affects its catalytic mechanism, as it acts as a competitive inhibitor at high concentrations. Molecular modeling has revealed that this molecule adopts a chair conformation with significant solvent exposure.</p>

<p>2-Acetamido-1,3,4,6-tetra-O-acetyl-2-deoxy-a-D-galactopyranose is a fluorinated complex carbohydrate that has been modified by methylation and acetylation. This product is a custom synthesis that has not been previously described in the scientific literature. It is synthesized from 2, 3, 4, 6 tetraacetyl alpha D galactopyranoside and 2 deoxy alpha D galactopyranose. The chemical properties of this compound are similar to those of other complex carbohydrates such as glycogen and heparin.</p>

<p>1,5-α-L-Arabinohexaose is a carbohydrate. It is a nonreducing sugar that can be found in plants. 1,5-α-L-Arabinohexaose has an optimum pH of 5 and an ethanol concentration of 0.02%. The enzyme form of 1,5-α-L-Arabinohexaose is α-(1→6)-glycosidase. This enzyme hydrolyzes the α-(1→6) glycosidic bond between two glucose residues in a polysaccharide chain to produce β-(1→4) bonds. It also hydrolyzes the β-(1→4) glycosidic bond between two galactose residues to produce β-(1→2) bonds and oxidizes the terminal carbon atom to produce aldehyde products.<br>A structural analysis of this carbohydrate was conducted using marine microorganisms and it was found that they contain galacturonic acid and sugar residues</p>

<p>D-Xylulose 5-phosphate sodium salt is a synthetic monosaccharide that can be used in the synthesis of oligosaccharides, polysaccharides, and complex carbohydrates. It is also used in glycosylation reactions. D-Xylulose 5-phosphate sodium salt has been fluorinated to provide better stability and solubility. The compound has a molecular weight of 206.06 g/mol and a CAS number of 105931-44-0. This product is available for custom synthesis upon request.</p>

<p>D-ribulose-5-phosphate sodium is a nucleotide sugar that is one of the ribonucleotides, which are fundamental components of RNA. D-ribulose 5-phosphate sodium has been shown to be an intermediate in the metabolism of ribulose and catalyzes the oxidation of d-arabinose. This enzyme also catalyses the synthesis of fatty acids and participates in reactions involving glycerolipids and phospholipids. The reaction mechanism involves a double displacement with simultaneous attack by a water molecule on C2' and C3'. When deuterium is present, it affects the rate of these reactions in a way that depends on the orientation of the substrate to the enzyme.</p>

<p>1,2,3,5-Tetra-O-acetyl-β-D-ribofuranose is a sugar that has been acetylated at the hydroxyl group. It has biological properties that are similar to those of 1,2,3,5-tetraacetyl-β-D-ribofuranose. This compound is an analog of 1,2,3,5-tetraacetyl-β-D-ribofuranose and can be used as a model system for studying the effects of acetylation on the properties of this molecule. Acetylation at the hydroxyl group in sugars can lead to low energy (chemical) properties. The acetylated form of this compound reacts with trifluoromethanesulfonic acid to give tetrafluoroethylene and ammonium sulfate in a model reaction solution. 1,2,3,5-Tetraacetyl β</p>

<p>4-Glucopyranosylmannose is a disaccharide compound, which is a synthetic carbohydrate derived from the enzymatic or chemical glycosylation processes. It consists of glucose and mannose units linked through a glycosidic bond. The compound is sourced through advanced synthetic methodologies involving specific glycosyltransferases or chemical catalysts that facilitate the precise attachment of these sugar moieties.</p>

<p>Please enquire for more information about 1,5-α-L-Arabinooctaose including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-O-Benzoyl-4,6-O-benzylidene-a-D-glucopyranoside is a synthetic carbohydrate with a structure that is similar to that of glucose. It has been shown to have anti-inflammatory properties in animal models and can be used for the treatment of inflammatory bowel disease and Crohn's disease. This compound has also been shown to inhibit the growth of bacteria such as Streptococcus pyogenes, Staphylococcus aureus, and Escherichia coli. 2-O-Benzoyl-4,6-O-benzylidene--aD glucopyranoside is soluble in water and has high purity with an average of 98%.</p>

<p>Methyl D-arabinofuranoside is an antimycobacterial agent that inhibits the synthesis of mycolic acids, which are important components of the cell wall of Mycobacterium tuberculosis. Methyl D-arabinofuranoside has been shown to be active against drug-resistant strains and has been well tolerated by animals. This compound can be synthesized from 2,4-dichlorophenylacetic acid and arabinose in two steps. The first step involves a three-component condensation reaction with sodium hydroxide, hydrochloric acid, and 2,4-dichlorophenylacetic acid. The second step is a nucleophilic attack on the pyran ring of methyl D-arabinofuranoside with hypophosphorous acid. Methyl D-arabinofuranoside can also be prepared by reacting sodium nitrosobenzene with sodium benzene sulfinate in alcoholic solution</p>

<p>3'-a-Sialyl-N-acetyllactosamine sodium salt is a high purity, custom synthesis sugar. It has been modified with fluorination, glycosylation, and methylation to provide the desired properties. This product is also available in other forms such as monosaccharide and saccharide. 3'-a-Sialyl-N-acetyllactosamine sodium salt can be used in various applications including Click modification, fluoroamination, glycosylation, carbonylation and methylation. CAS No. 350697-53-9</p>

<p>Please enquire for more information about N’-Nitrosonornicotine N-β-D-glucuronide (mixture of diastereomers) hydrate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Decyl D-glucopyranoside is a sodium salt of decyl D-glucopyranoside that is used as a detergent additive in cleaning compositions. Decyl D-glucopyranoside has shown antimicrobial activity against both Gram-positive and Gram-negative bacteria, including methicillin resistant Staphylococcus aureus (MRSA) and Clostridium perfringens. Decyl D-glucopyranoside has also been shown to have chemical stability at high temperatures, making it useful in the manufacture of lacrimal gland preparations and cationic surfactants.</p>

<p>Ribitol is a sugar alcohol that is found in all living organisms. It is also used as a source of carbon and energy in the form of D-ribitol-5-phosphate, which can be synthesized from ribose 5-phosphate by means of an enzymatic reaction. Ribitol 5 phosphate is used for the synthesis of monoclonal antibodies, which are useful for studying enzyme activities, immunoassays, and cell surface receptors. This compound has been shown to have regulatory effects on the expression of genes encoding fatty acid biosynthesis enzymes. Ribitol 5 phosphate has been detected using magnetic resonance spectroscopy techniques in glycan structures and galacturonic acid residues.</p>