Glycoscience

<p>Benzyl 2-acetamido-2-deoxy-4-O-(b-D-galactopyranosyl)-a-D-galactopyranoside is a synthetic saccharide. The chemical structure of this material has been modified by fluorination, methylation, and click modification. This product is soluble in water and can be used as a starting material for the synthesis of polysaccharides.</p>

<p>2-Acetamido-2-deoxy-4-O-(b-D-galactopyranosyl)-D-galactopyranose is a glycan that binds to human lymphocytes and induces their death. It is a glycan that has been shown to be sialylated, which may be due to its high degree of homology with other glycan structures. The 2-acetamido group confers the ability to bind to sialyltransferases, which are enzymes that catalyze the transfer of sialic acid from glucose onto complex carbohydrates. This binding inhibits the enzymatic activity of these enzymes and prevents the addition of sialic acid onto oligosaccharides, preventing antigen presentation. 2-Acetamido-2-deoxy-4-O-(b-D-galactopyranosyl)-D-galactopyranose is also known as "sialic acid" or "</p>

Gum tragacanth is an exudate gum from species of Astragalus trees mainly grown in Iran and Turkey. Tragacanth finds applications as an effective emulsifying and thickening agent in the food and pharmaceutical industries. The gum is a slightly acidic salt consisting of two fractions namely the water soluble tragacanthin and the fraction bassorin which swells in water to form a gel. Water soluble tragacanthin is reported as a branched arabiogalactan which is soluble in 70% ethanol. The acidic bassorin has a chain of (1,4)-linked a-D-galacturonic acid units some of which are substituted at O-3 with β-D-xylopyranosyl units and some of these being terminated with galactose or fucose.

<p>Chitosan oligosaccharide HCl is a water-soluble, biocompatible polymer with an average molecular weight of 2,000. It has been shown to have hypoglycemic effects in vivo and inhibitory properties against inflammatory bowel disease. Chitosan oligosaccharide HCl also exhibits an ability to enhance the activity of monoclonal antibodies directed against human tumor cells. This effect may be due to the ability of chitosan oligosaccharide HCl to bind to antigens on the surface of tumor cells and facilitate antibody binding.</p>

<p>This gamma-cyclodextrin (γ-CD) derivative is a modified cyclic oligosaccharide composed of eight glucose units, featuring a larger cavity size than α- and β-cyclodextrins. This structural characteristic allows γ-CDs to form inclusion complexes with a wider range of guest molecules, making it particularly versatile in various industries. In the food sector, it is used as a carrier and stabilizer for flavors, fat-soluble vitamins, and polyunsaturated fatty acids, protecting volatile compounds from evaporation. In pharmaceuticals, it enhances the solubility and bioavailability of poorly water-soluble drugs and, thanks to its larger ring size, allows for the encapsulation of larger molecules or even entire drug molecules. γ-CDs and derivatives are also used for environmental remediation and, in analytical chemistry, for the extraction and concentration of target substances.</p>

<p>2,3,5-Tri-O-(p-toluoyl)-1-O-acetyl-4-thio-D-ribofuranose is a custom synthesis of a complex carbohydrate. It is an Oligosaccharide with CAS No. and a Polysaccharide that has been modified by Methylation and Glycosylation. It is also a Modification of saccharide, which is a Carbohydrate that contains the sugar, glucose. The purity of 2,3,5-Tri-O-(p-toluoyl)-1-O-acetyl-4-thio--D--ribofuranose is high and it has been Fluorinated for Synthetic purposes.</p>

<p>Varenicline N-glucoside is a modification of varenicline, which is an antagonist of the nicotinic acetylcholine receptor. This compound has been synthesized using custom synthesis and glycosylation to obtain high purity. It has been methylated and fluorinated in order to remove any impurities. Varenicline N-glucoside is a carbohydrate with a molecular weight of 581.5 g/mol, consisting of one monosaccharide and one disaccharide. It also contains a complex carbohydrate with an oligosaccharide chain that is composed of glycosylation and saccharide units. The CAS number for this compound is 873302-31-9.</p>

<p>3,5-Dideoxy-N-(1-hexyl)-3,5-imino-D-xylopentitol is a synthetic monosaccharide that is used in the production of complex carbohydrates. It can be modified with fluorination and methylation to produce 3,5-dideoxy-N-(1-hexyl)-3,5-[(2-[(2,6-difluoro phenoxy)methyl]phenyl]imino)D-xylopentitol. The compound has been shown to have antiviral properties and has been used in the synthesis of glycosaminoglycans.</p>

<p>Methyl 2,3,4,6-tetra-O-benzyl-D-galactopyranoside is a trisaccharide that binds to the fluorescent chromophore. It has been shown to have strong binding activity and can be used for the labeling of carbohydrates. Methyl 2,3,4,6-tetra-O-benzyl-D-galactopyranoside is also used in assays to detect toxins or as a fluorescent label for polymers. This compound can be synthesized by reacting methyl 4,6-dibenzyloxybenzoate with glucose in methanol.</p>

<p>This gamma-cyclodextrin (γ-CD) derivative (Suc-γ-CD) is a modified cyclic oligosaccharide composed of eight glucose units, featuring a larger cavity size than α- and β-cyclodextrins. This structural characteristic allows γ-CDs to form inclusion complexes with a wider range of guest molecules, making it particularly versatile in various industries. In the food sector, it is used as a carrier and stabilizer for flavors, fat-soluble vitamins, and polyunsaturated fatty acids, protecting volatile compounds from evaporation. In pharmaceuticals, it enhances the solubility and bioavailability of poorly water-soluble drugs and, thanks to its larger ring size, allows for the encapsulation of larger molecules or even entire drug molecules. γ-CDs and derivatives are also used for environmental remediation and, in analytical chemistry, for the extraction and concentration of target substances.</p>

<p>Laminaran is a polysaccharide that co-occurs with fucoidan and alginate in brown seaweeds such as Laminaria digitata, Laminaria cloustoni, Eisenia bicyclis and Thallus laminariae. It is a β-1,3-linked glucan which it is claimed stimulates the immune system in mammals and fish.<br>The image was kindly provided by Prof Mike Guiry from Cork who runs ‘The Seaweed Site’.</p>

Methyl 2,3,6-tri-O-benzoyl-4-deoxy-4-fluoro-a-D-glucopyranoside is a sugar that is synthetically modified. This product has been fluorinated and glycosylated with a benzoyl group at C2 position. It contains methyl groups attached to the ring carbons at C1 and C6 positions. The product is also an oligosaccharide that contains two monosaccharides (sugar units) linked by an alpha (1→4) glycosidic bond. Methyl 2,3,6-tri-O-benzoyl-4-deoxy-4-fluoro-a-Dglucopyranoside can be used as a synthetic building block for the synthesis of complex carbohydrate structures.

<p>Dodecyldeoxynojirimycin is a polyketide natural product that has been shown to be a potent inhibitor of the synthesis of mannose-containing glycoproteins, including glucans and chitooligosaccharides. It binds to the active site of glucan synthetase and prevents the formation of glucose residues, which blocks glucan biosynthesis. Dodecyldeoxynojirimycin has also been shown to have anti-inflammatory properties.</p>

<p>Methyl 4,6-O-benzylidene-2-benzyloxycarbonylamino-2-deoxy-a-D-glucopyranose is a custom synthesized compound. It is a polysaccharide that is modified with fluorine and methyl groups. The chemical structure of this compound includes a glucose molecule with an amino group at the C1 position and an acetyl group at the C4 position. This modification increases the solubility and stability of this compound. Methyl 4,6-O-benzylidene-2-benzyloxycarbonylamino-2-deoxy--A D glucopyranose has been used in research as a model for glycosylation.</p>

<p>Phenyl 2-O-benzoyl-3-O-benzyl-4-O-levulinoyl-b-D-thioglucuronide methyl ester is a high purity, custom synthesis, sugar that has been click modified with fluorination. It can be used in glycosylation and synthetic modification. The CAS number for this compound is 123456. It is an oligosaccharide that contains saccharides, carbohydrates, and complex carbohydrates.</p>

<p>Fluorinated glucose analog</p>

<p>2,3-Diaza-1,1,4,4-tetraphenyl-trans-butadiene is a synthetic compound that can be used as a methylating agent. This compound has been shown to be an effective sugar donor for the synthesis of complex carbohydrates with high purity. 2,3-Diaza-1,1,4,4-tetraphenyl-trans-butadiene is also useful for click modification and glycosylation.</p>

<p>(2R,3R,4R,5R)-2-(3-hydroxy-4-methoxyphenyl)-5-(hydroxymethyl)pyrrolidine-3,4-diol is an imino-sugar</p>

<p>Core antigen fragment in ABO blood group system</p>

<p>Substrate for UDP-3-O-acyl-GlcNAc deacetylase</p>

<p>2,3:5,6-Di-O-isopropylidene-a-D-mannofuranose is a nutrient solution that can be used in tissue culture. It is a complex sugar with an active hydroxyl group and a hydrogen bond. This compound has been shown to have antiviral activity against HIV in the laboratory. 2,3:5,6-Di-O-isopropylidene-a-D-mannofuranose is also able to inhibit the growth of liver cells and can be used for diagnostic purposes.</p>

<p>Caffeic acid 3-O-b-D-glucopyranoside is a naturally occurring phenolic compound found in plants. It is a white to off-white powder that is soluble in methanol, ethanol, and water. Caffeic acid 3-O-b-D-glucopyranoside has been shown to have antioxidant properties by increasing the mitochondrial membrane potential in erythrocytes and reducing free radicals. It also may have anticancer activity due to its ability to inhibit tumor growth in vivo studies.</p>

<p>3,4:5,6-Di-O-isopropylidene-2-O-tert.butyldimethylsilyl-L-idose is a custom synthesis that is used in the synthesis of oligosaccharides and polysaccharides. It is also used for glycosylation reactions and click chemistry modifications. 3,4:5,6-Di-O-isopropylidene-2-O-tert.butyldimethylsilyl L -idose has CAS No. 53762–04–2 and a sugar type of carbohydrate. This product is a high purity with 98% or greater purity.</p>

<p>7'-Hydroxypropranolol-b-D-glucuronide is a synthetic compound with a molecular formula of C21H28F3NO6. It has a melting point of 155 °C, and it is soluble in water. 7'-Hydroxypropranolol-b-D-glucuronide is an intermediate in the synthesis of other compounds, and it can be used as a building block for custom synthesis. This compound can be modified with click chemistry or saccharide linkages, providing additional opportunities for modification.</p>

<p>2-C-(tert.Butylmethylsilyloxy)methyl-2,3:5,6-di-O-isopropylidene-D-mannono-1.4-lactone is a custom synthesis of a complex carbohydrate with Oligosaccharide, CAS No., Polysaccharide and Modification properties. It is a saccharide that is Methylation and Glycosylation modified. This product has Click modification and Carbohydrate properties. 2C-(tert.Butylmethylsilyloxy)methyl-2,3:5,6-di-O-isopropylidene-D-mannono 1,4 lactone is a high purity product with Fluorination and Synthetic properties.</p>

<p>Disrupting agents are compounds that inhibit the function of a protein. These agents are able to bind to proteins and disrupt their normal function, leading to cell death. Picolinic acid is one such agent, which binds to proteins that contain an active site with a metal ion. It has been shown to be effective in reducing tumor cells and drug efficacy. Disrupting agents have also been shown to induce apoptosis by activating caspases, which are proteases that process proteins in cells. Research on these agents has shown anticancer potential in drug research and cancer treatment.</p>

<p>4-Methoxyphenyl 3-O-(2,3,4,6-Tetra-O-acetyl-b-D-galactopyranosyl)-2-azido-4,6-O-benzylidene-2-deoxy-b -D -galactopyranoside is a sugar that can be methylated or modified with other saccharides. It has CAS No. 91485 and can be synthesized by Click chemistry. The modification of the sugar includes glycosylation and fluorination. This compound is a complex carbohydrate that is used in synthetic chemistry.</p>

<p>2-Aminophenyl 2,3,4-tri-O-acetyl-b-D-glucuronide methyl ester is a glycosylation reagent and can be used in synthesis of oligosaccharides and sugar. This chemical has been modified with fluorination, methylation and monosaccharide modification to provide a high purity product. It is also available in complex carbohydrate form.</p>

<p>Methyl 7,8,9-Tri-O-acetyl-5-N,4-O-carbonyl-3,5-dideoxy-2-S-phenyl-2-thio-D-glycero -b-(1→4)-D-(1→3)-galacto-(1→4)-2-[N-[(1R,2R)-2-(methoxyimino)ethoxy]acetamido]-nonulopyranosylonate is a synthetic carbohydrate. It has been modified with methylation at position 7 and 8 of the sugar and click modification. Methyl 7,8,9 -triacetyl 5 -N, 4 -O carbonyl 3 , 5 -dideoxy 2 -S phenyl 2 -thiophenediol glycero b D galacto 2 nonulopyranoside is a complex carbohydrate.</p>

<p>Trehalose is a naturally occurring disaccharide found in many organisms.Its role in nature is as versatile as its applications in the laboratory. Trehalose is synthesized by cells in response to stress and helps retaining the cellular integrity under tough conditions: An important function of Trehalose is to stabilize protein structures and to prevent proteins from their degradation. Researchers use Trehalosefor instance as a carbon source in selective microbiological media, as desiccation protectant and for cryoprotection.</p>

<p>Carboxymethyl cellulose is used in food as a viscosity modifier, thickener, to stabilise emulsions and are found in gluten-free and reduced-fat products. It is also a constituent of toothpaste, laxatives, diet pills, water-based paints, detergents, textile sizing, and various paper products.  In laundry detergents, it is used as a soil suspension polymer. It is also used in pharmaceuticals as a thickening agent and in the oil-drilling industry as a viscosity modifier and water-retaining agent.</p>

<p>Methyl 6-O-tert-butyldiphenylsilyl-2,3,4-tri-O-pivaloyl-a-D-galactopyranoside is a high purity custom synthesis sugar. The methyl group on the sugar prevents it from being hydrolyzed by esterases and glucuronidases. This product can be used in glycosylation and sialylation reactions to create saccharides with a modified oligosaccharide. This product is synthesized in lab conditions, which includes fluorination, glycosylation, methylation, and modification steps. It has CAS number 1314897-28-5 and molecular weight of 454. Methyl 6-O-tert-butyldiphenylsilyl -2,3,4 -tri - O -pivaloyl -a - D -galactopyranoside is an oligosacchar</p>

<p>6-Epi-castanospermine is a nitro compound that is synthesized by the allylic oxidation of castanospermine. It has been shown to inhibit glycosidases and glycosidase inhibitors in vitro, including those from the families of α-amylase, α-L-arabinofuranosidases, β-hexosaminidases, α-glucuronidases, and phytases. 6-Epi-castanospermine has also been used as an intermediate for the synthesis of chiral polyhydroxylated compounds. The 13C NMR spectrum of this compound was found to be diagnostic for its structural assignment.</p>

<p>3-O-Benzyl-D-glucopyranose is a molecule that has been optimized for its autodock score. It binds to the active site of peptidases, which are enzymes that break down proteins in the body. 3-O-Benzyl-D-glucopyranose is a nauclea that can be used as a pharmacokinetic (PK) or pharmacodynamic (PD) inhibitor. Nauclea have shown effectiveness against diabetes by preventing the breakdown of glucose, which is an important energy source for cells. 3-O-Benzyl-D-glucopyranose has also been found to be an effective inhibitor of DPPIV, which is an enzyme involved in breaking down insulin and other hormones in blood circulation. In vitro studies have shown that it may also have antiaging properties due to its ability to inhibit production of inflammatory cytokines such as IL1β, IL6, and TNFα.</p>

<p>Chitosan is the deacetylated form of chitin. The polysaccharide is deacetylated in order to render it soluble, which is then possible at pH values of less than 7 (normally in dilute acid). This then allows the material to be used in a number of industrial applications as a binder and film former.</p>

<p>b-D-Allopyranose is a monosaccharide that has been modified with fluorine. It is used as a substrate for the production of oligosaccharides and polysaccharides, which are important biomolecules in cell walls and membranes. b-D-Allopyranose can be customized to suit your needs with Click chemistry, Methylation, or other modifications. We offer high purity b-D-Allopyranose at competitive prices.</p>

<p>Nematode glycan mediating activation of macrophages</p>

<p>2-Azido-2-deoxy-3,4-O-isopropylidene-6-O-toluenesulfonyl-L-idonic acid methyl ester is a synthetic sugar that has the CAS number of 2147690. It is a modified saccharide that can be used for glycosylation and click chemistry. This product is also available in custom synthesis, high purity, and fluorination.</p>

<p>A short chain isomer of inulin</p>

<p>5-Amino-3-β-D-ribofuranosylthiazolo[4,5-d]pyrimidin-2,7(3H,6H)-dione (ATZ) is a prodrug that is converted to the active drug ATZ. ATZ has been shown to be effective against hepatitis C virus in vitro assays and in vivo in animal models. It inhibits viral replication by inhibiting the protein synthesis of the virus and its ability to replicate. ATZ also has been shown to be effective against infectious diseases such as herpes simplex virus, inflammatory diseases such as rheumatoid arthritis, and cancer. The drug is an oral prodrug that must be activated by intestinal bacteria before it can be absorbed into the bloodstream. It is chemically stable and does not undergo significant metabolism after being absorbed into the body.</p>

<p>N-(5-Carboxypentyl)-deoxymannojirimycin hydrochloride is a high purity, custom synthesis, CAS No. 104154-10-1. It is a sugar that contains the Click modification, fluorination, glycosylation, and synthetic modifications. It contains methylation, modification and oligosaccharide or monosaccharide saccharides. This compound has been modified by Carbohydrate Complex.</p>

<p>4-O-(2-Acetamido-2-deoxy-a-D-glucopyranosyl)-D-galactopyranose is a disaccharide that contains two acetamido groups. It is an acceptor for the receptor activity and has been shown to have biological properties. This compound can be synthesized using lactam and glycosylation with the use of sodium cyanoborohydride. 4-O-(2-Acetamido-2-deoxy-a-D-glucopyranosyl)-D-galactopyranose can also be used in the synthesis of oligosaccharides, which are important for cellular function. 4O-(2 Acetamido 2 deoxy a D glucopyranosyl) D galactopyranose shows high affinity for pertussis bacteria and bordetella pertussis. It binds to the surface of these bacteria,</p>

<p>D-Maltose 1-phosphate dipotassium salt is a disaccharide that can be used in the synthesis of oligosaccharides and polysaccharides. It is also an excellent candidate for further modification.</p>

<p>2-Azido-2-deoxy-(S)-3,4-O-phenylmethylene-D-arabinonic acid 1,5-lactone is a custom synthesis. It is a modification of the natural sugar arabinose. The chemical structure has been modified by fluorination and methylation. This product can be used in the synthesis of monosaccharide and saccharide oligosaccharides. 2-Azido-2-deoxy-(S)-3,4-O-phenylmethylene-D-arabinonic acid 1,5 -lactone is an organic compound that belongs to the group of carbohydrates and polysaccharides.</p>

<p>5'-Hydroxypropranolol-b-D-glucuronoside is a synthetic glycosylate of 5'-hydroxypropranolol. It can be modified with fluorine, methyl or click chemistry. The chemical name is O-(2,3,4,5-tetrafluorobenzoyl)glycine and the CAS number is 878183-10-6. This compound has a molecular weight of 471.8 g/mol and an empirical formula of C14H9F5NO5. It can be used in the synthesis of oligosaccharides and polysaccharides.</p>

<p>This beta-cyclodextrin (β-CD) derivative is an azido-functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.</p>

<p>(+)-Pinoresinol-b-D-glucoside is a fluorinated, monosaccharide that is synthetically produced by glycosylation. It can also be modified using methylation and click chemistry. The chemical formula for (+)-pinoresinol-b-D-glucoside is C10H14O8. It has a molecular weight of 288.24 g/mol and an empirical formula of (C10H14O8)2. The CAS number for this compound is 69251-963. This product is in the Carbohydrate family and has a purity level of &gt;99%.</p>

<p>Diethylstilbestrol (DES) is an endogenous substance that has been shown to be a potent estrogen. It is metabolized in the body to form stilbestrol glucuronide, which is excreted in the urine. Radiolabeling studies have shown that DES has a chemical structure similar to estradiol, although its pharmacologic effects are not as potent. Diethylstilbestrol glucuronide can be used for the diagnosis of cancer and other diseases by using nuclear medicine techniques such as positron emission tomography (PET) and single-photon emission computed tomography (SPECT). Studies have also demonstrated that DES can induce erythropoietic protoporphyria in animals.</p>

<p>Intermediate in the synthesis of prostaglandins</p>

<p>3,4-Di-O-acetyl-D-arabinal is a spiroketal monofluoride that is known to be an efficient method for the synthesis of β-unsaturated aldehydes. It can be prepared by the hydration of enantiopure allyl chloroformate followed by reductive elimination with triflic acid and acidic hydrolysis. 3,4-Di-O-acetyl-D-arabinal has been used in the synthesis of biologically active molecules such as polyketides, peptides and natural products.</p>