Antifúngicos
Los antifúngicos son compuestos específicamente diseñados para detener, prevenir y eliminar el crecimiento de hongos. En esta categoría, encontrará una amplia variedad de agentes antifúngicos esenciales para aplicaciones de investigación y terapéuticas. Estos compuestos son cruciales en el tratamiento de infecciones fúngicas y en la prevención de su recurrencia, lo que los convierte en herramientas vitales tanto en entornos médicos como agrícolas. Investigadores y profesionales de la salud pueden explorar numerosos antifúngicos para comprender sus mecanismos, optimizar su eficacia y desarrollar nuevos tratamientos para combatir cepas de hongos resistentes. La extensa selección de antifúngicos respalda los avances continuos en la investigación fúngica y el desarrollo de terapias antifúngicas efectivas.
Se han encontrado 837 productos de "Antifúngicos"
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5,6-Dehydromethysticin
CAS:Producto controlado<p>Applications 5,6-Dehydromethysticin is a proposed intermediate in the synthesis of 3-Hydroxyhispidin (H943133), a derivative of Hispidin. Hispidin (H436450) is a naturally occuring precursor to fungal luciferin responsible for luminosity in mushrooms.<br>References Lee, Y. et al.: Biol. Pharm. Bull., 31, 10 (1968); Purtov, K. et al.: Angew. Chem. Int. Ed., 54, 8124 (2014);<br></p>Fórmula:C15H12O5Forma y color:NeatPeso molecular:272.2531-(4-Chlorophenyl)-3-[(2-nitrophenyl)methoxy]pyrazole
CAS:Producto controlado<p>Applications 1-(4-Chlorophenyl)-3-[(2-nitrophenyl)methoxy]pyrazole is an intermediate for the synthesis of Pyraclostrobin-d6 (P840402). Isotope labelled Pyraclostrobin is a fungicide for use in seed grass and food crops.<br>References Gyldenkaerne, S., et al.: Pestic Sci., 55, 1210 (1999), Pennington, D., et al.: Environ. Sci. Technol., 39, 1119 (2005), Wang, S., et al.: Food Control., 18, 731 (2007),<br></p>Fórmula:C16H12ClN3O3Forma y color:NeatPeso molecular:329.741,4-Bis([1,1'-biphenyl]-4-ylphenylmethyl)-1H-imidazole
Producto controlado<p>Applications 1,4-Bis([1,1'-biphenyl]-4-ylphenylmethyl)-1H-imidazole is derived from 5-([1,1’-Biphenyl]-4-ylphenylmethyl)-1H-imidazole (B397925), which is a structural isomer of Bifonazole (B383400) that is an anti-fungal agent used in the treatment of skin diseases. Bifonazole causes an increase in Ca2+ concentration and triggers cell death in PC3 human prostate cancer cells.<br>References Cheng, J. et al.: J. Recep. Sign. Transduct., 34, 493 (2014); Chen, Z. et al.: Mol. Pharm., 12, 590 (2015);<br></p>Fórmula:C41H32N2Forma y color:NeatPeso molecular:552.712-Methylbenzothiazole-6-carboxylic Acid (~90%)
CAS:Producto controlado<p>Applications 2-Methylbenzothiazole-6-carboxylic Acid (~90%) is a useful research chemical, a reagent for the synthetic studies on fungicidal agents.<br>References Saikachi, H., et al.: Yakugaku Zasshi, 78, 376 (1958); Bosco, M., et al.: Annali di Chimica, 58, 1148 (1968)<br></p>Fórmula:C9H7NO2SPureza:~90%Forma y color:NeatPeso molecular:193.22N-Chloro-2,2,6,6-tetramethyl-4-piperidyl Methacrylate
CAS:Producto controlado<p>Applications A new N-halamine monomer was synthesized and used to prepare water-based polymeric N-halamines by emulsion polymn. Also, the compound was tested for antibacterial activity against Candida albicans, Staphylococcus aureus, and Escherichia coli.<br>References Kohl, H., et al.: J. Pharm. Sci., 69, 1292 (1980), Greenberger, P., et al.: Clin. Allergy Immunol., 16, 449 (2002), Gant, V., et al.: J. Antimicrob. Chemother., 60, 294 (2007), Pestka, J., et al.: Toxicol. Sci., 104, 4 (2008),<br></p>Fórmula:C13H22ClNO2Forma y color:NeatPeso molecular:259.77Methyl DL-Mandelate
CAS:Producto controlado<p>Applications Methyl DL-Mandelate is a substrate for lipase B from Candida antarctica.<br>References Santos, J.C.S., et. al.: Enzyme Microb. Tech., 77, 1 (2015)<br></p>Fórmula:C9H10O3Forma y color:NeatPeso molecular:166.17(2R,3R)-3-(2,4-Difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)butan-2-yl methanesulfonate
CAS:Producto controladoFórmula:C13H15F2N3O4SForma y color:NeatPeso molecular:347.34Dictamnine
CAS:Producto controlado<p>Applications Dictamnine is an herbal extract from the root of Dictamnus dasycarpus, and exhibits anti-microbial activity against bacteria and fungi. Phytotoxic agent.<br>References Guo, N. et al.: Yeast., 25, 631 (2008); Schempp, C. et al.: Planta. Med., 72, 941 (2006);<br></p>Fórmula:C12H9NO2Forma y color:NeatPeso molecular:199.212-(2-((6-(2-Cyanophenoxy)pyrimidin-4-yl)oxy)phenyl)-2-oxoacetic Acid Methyl Ester
CAS:Producto controlado<p>Applications 2-(2-((6-(2-Cyanophenoxy)pyrimidin-4-yl)oxy)phenyl)-2-oxoacetic Acid Methyl Ester is an intermediate in the synthesis of (Z)-Azoxystrobin (A965155), a fungicide that inhibits mitochondrial respiration by blocking electron transfer between cytochromes b and c1<br>References Smalling, K., et al.: Environ. Toxicol. Chem., 29, 2593 (2010), Lu, X., et al.: Phytopathol., 100, 1162 (2010), Schafer, R., et al.: Environ. Sci. Technol., 45, 1665 (2011),<br></p>Fórmula:C20H13N3O5Forma y color:NeatPeso molecular:375.33Curvulin
CAS:Producto controlado<p>Applications Curvulin is a phototoxin that inhibits microtuble assembly.<br></p>Fórmula:C12H14O5Forma y color:Off-WhitePeso molecular:238.24Nitrefazole
CAS:Producto controlado<p>Applications Nitrefazole is a nitroimidazole derivative with the ability to inhibit aldehyde dehydrogenase, and enzyme crucial to the metabolism of alcohol. This compound is suitable for aldehyde dehydrogenase (ALDH) related research.<br>References Klink, R. et al.: Arzneimittelforschung., 35, 1220 (1985); Koda L. et al.: Life Sci., 35, 1659 (1984);<br></p>Fórmula:C10H8N4O4Forma y color:Light Yellow To YellowPeso molecular:248.19Ethyl 1-methyl-4-nitroimidazole-2-carboxylate
CAS:Producto controlado<p>Applications Ethyl 1-methyl-4-nitroimidazole-2-carboxylate<br></p>Fórmula:C7H9N3O4Forma y color:NeatPeso molecular:199.16cis-2-(2,4-Dichlorophenyl)-2-(4H-1,2,4-triazol-4-ylmethyl)-1,3-dioxolane-4-methanol
CAS:Producto controlado<p>Applications cis-2-(2,4-Dichlorophenyl)-2-(4H-1,2,4-triazol-4-ylmethyl)-1,3-dioxolane-4-methanol is an impurity in the synthesis of Itraconazole (I937500); an orally active antimycotic structurally related to Ketoconazol.<br>References Espinel-Ingroff, A., et al.: Antimicrob. Agents Chemother., 26, 5 (1984); Heykants, J., et al.: Mycoses, 32, Suppl 1, 67 (1989); Sugar, A.M.,et al.: Curr. Clin. Top. Infect. Dis., 13, 74 (1993)<br></p>Fórmula:C13H13Cl2N3O3Forma y color:NeatPeso molecular:330.17TH-302
CAS:Producto controlado<p>Applications TH-302 is a 2-nitroimidazole triggered hypoxia-activated prodrug (HAP) of bromo-isophosphoramide mustard. Studies have shown that TH-302 treatment exhibited hypoxia-selective cytotoxicity and DNA damage in human cancer cell<br>References Meng, F. et al.: Mol. Cancer Ther., 11, 740 (2012); Liu, Q. et al.: Cancer Chemother. Pharmacol., 69, 1487 (2012); Sun, J.D. et al.: Clin. Cancer Res., 18, 758 (2012);<br></p>Fórmula:C9H16Br2N5O4PForma y color:NeatPeso molecular:449.041-Methoxy-1-oxopropan-2-yl N-(2,6-Dimethylphenyl)-N-(2-methoxyacetyl)alaninate
Producto controlado<p>Applications 1-Methoxy-1-oxopropan-2-yl N-(2,6-Dimethylphenyl)-N-(2-methoxyacetyl)alaninate is a useful intermediate for organic synthesis processes. Potentially useful as a phytofungicide.<br>References Fr. Demande (1980), FR 2455574 A1<br></p>Fórmula:C18H25NO6Forma y color:NeatPeso molecular:351.3942-(1-(Allyloxy)-2-(1H-imidazol-1-yl)ethyl)-3,5-dichlorophenol
Producto controladoFórmula:C14H14Cl2N2O2Forma y color:NeatPeso molecular:313.179Aureothin
CAS:<p>Aureothin is a bioactive compound, classified as a polyketide antibiotic, which is derived from the culture of the bacterium Streptomyces thioluteus. This compound operates primarily through the inhibition of protein synthesis by interfering with the aminoacylation of tRNA with specific amino acids. Its mode of action disrupts cellular protein synthesis, which is essential for cell growth and function, leading to its potent antibacterial and antifungal activities.</p>Fórmula:C22H23NO6Pureza:Min. 95%Forma y color:PowderPeso molecular:397.42 g/molNaftifine N-Oxide
CAS:<p>Naftifine N-Oxide is an antifungal agent, which is derived from synthetic chemical processes. Its structure is based on the modification of the known antifungal, naftifine, by introducing an N-oxide functional group, which may enhance certain pharmacokinetic properties. As a synthetic derivative, Naftifine N-Oxide is specifically designed to interfere with the biosynthesis of ergosterol, an essential component of fungal cell membranes. By inhibiting squalene epoxidase, an enzyme crucial to the ergosterol pathway, Naftifine N-Oxide effectively disrupts the development and maintenance of the fungal cell membrane, compromising cell integrity and leading to antifungal activity.</p>Fórmula:C21H21NOPureza:Min. 95%Peso molecular:303.4 g/molMiconazole
CAS:<p>Anti-fungal; sterol 14α-demethylase inhibitor</p>Fórmula:C18H14Cl4N2OPureza:Min. 95 Area-%Forma y color:White Off-White PowderPeso molecular:416.13 g/mol
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