Antifúngicos
Los antifúngicos son compuestos específicamente diseñados para detener, prevenir y eliminar el crecimiento de hongos. En esta categoría, encontrará una amplia variedad de agentes antifúngicos esenciales para aplicaciones de investigación y terapéuticas. Estos compuestos son cruciales en el tratamiento de infecciones fúngicas y en la prevención de su recurrencia, lo que los convierte en herramientas vitales tanto en entornos médicos como agrícolas. Investigadores y profesionales de la salud pueden explorar numerosos antifúngicos para comprender sus mecanismos, optimizar su eficacia y desarrollar nuevos tratamientos para combatir cepas de hongos resistentes. La extensa selección de antifúngicos respalda los avances continuos en la investigación fúngica y el desarrollo de terapias antifúngicas efectivas.
Se han encontrado 909 productos de "Antifúngicos"
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Y18501
CAS:Y18501, an oxysterol-binding protein (OSBPI) inhibitor structurally akin to Oxathiapiprolin, demonstrates potent inhibition against Phytophthora spp.Fórmula:C27H26F2N6O2SForma y color:SolidPeso molecular:536.6Antifungal agent 48
CAS:Antifungal agent 48 (Example 308), active against Cryptococcus neoformans, exhibits a minimum inhibitory concentration (MIC) value of 11 μM [1].Fórmula:C13H10O4SForma y color:SolidPeso molecular:262.28Icofungipen
CAS:Icofungipen is an oral antifungals with active against Candida species.Fórmula:C7H11NO2Pureza:98%Forma y color:SolidPeso molecular:141.17Loflucarban
CAS:Loflucarban (Fluonilid) is an antimycotic compoud.Fórmula:C13H9Cl2FN2SPureza:98.08% - 98.15%Forma y color:SolidPeso molecular:315.19Antifungal agent 66
CAS:Antifungal agent 66 (compound 10) exhibits broad-spectrum antifungal activity against seven phytopathogenic fungal mycelia and significant inhibitory effects onFórmula:C19H25ClO6Forma y color:SolidPeso molecular:384.85Laxifloran
CAS:Laxifloran possesses antibacterial and antifungal properties.Fórmula:C17H18O5Forma y color:SolidPeso molecular:302.322-Dodecanol
CAS:2-Dodecanol suppresses both hyphal development and SIR2 gene expression in Candida albicans [1].Fórmula:C12H26OForma y color:SolidPeso molecular:186.33Antifungal agent 26
CAS:Pradimicin A derivative 26 exhibits antifungal, antiviral, and antiparasitic properties by attaching to d-mannose (Man)-rich glycans in pathogenic organisms [1Fórmula:C40H45N3O18Forma y color:SolidPeso molecular:855.79Antifungal agent 49
CAS:Antifungal agent 49 (Example 112) exhibits activity against Cryptococcus neoformans, demonstrating a minimum inhibitory concentration (MIC) of 49 μM [1].Fórmula:C15H12O4Forma y color:SolidPeso molecular:256.25Eucalyptacid A
CAS:Eucalyptacid A, a metabolite with antifungal properties, demonstrates efficacy against Alternaria solani, displaying minimum inhibitory concentrations (MIC)Fórmula:C17H32O5Forma y color:SolidPeso molecular:316.43TMTD (Tetramethylthiuram disulfide)
CAS:TMTD (Tetramethylthiuram disulfide) reduces the growth performance of chickens by reducing liver index, while increasing kidney, heart and spleen index. In addition, TMTD also induces tibial chondrodysplasia (TD) by regulating the expression of VEGF, HIF-1α and WNT4. As a super accelerator in rubber processing, TMTD plays an important role in the low-temperature vulcanization process and is a key pesticide in agriculture.Fórmula:C6H12N2S4Forma y color:SolidPeso molecular:240.43Orysastrobin
CAS:Orysastrobin, a "quinone outside inhibitor" (QoI) fungicide, demonstrates outstanding efficacy in controlling rice leaf and panicle blast as well as sheathFórmula:C18H25N5O5Forma y color:SolidPeso molecular:391.42PF-184563
CAS:PF-184563 is an effective and selective non-peptide antagonist of the V1a receptor with oral activity, suitable for studying Raynaud's disease dysmenorrhoea.Fórmula:C21H23ClN6Pureza:99.67%Forma y color:SolidPeso molecular:394.9Antifungal agent 24
CAS:<p>Antifungal agent 24 (Compound 6) is an antifungal agent that inhibits Candida albicans (MIC: 0.03 μg/ml).</p>Fórmula:C24H18F2N4OForma y color:SolidPeso molecular:416.42TMV-IN-5
CAS:<p>TMV-IN-5 (compound 1a) serves as an antiviral/antifungal agent, specifically targeting and inhibiting the assembly of the tobacco mosaic virus (TMV) by binding</p>Fórmula:C22H23N3SForma y color:SolidPeso molecular:361.5Antiproliferative agent-33
CAS:Antiproliferative Agent-33 (Compound 2g) serves as an anti-proliferative, antifungal, and antibacterial agent, effectively inhibiting the proliferation of MDA-Fórmula:C21H26N2OForma y color:SolidPeso molecular:322.44Methyl 3,4-dimethoxycinnamate
CAS:Methyl 3,4-dimethoxycinnamate impedes uredospore germination and concurrently inhibits global DNA methylation in Hep3B cells [1] [2].Fórmula:C12H14O4Forma y color:SolidPeso molecular:222.24Prochloraz manganese
CAS:Prochloraz manganese, an antifungal agent utilized in the agricultural sectors [1], serves to protect crops by inhibiting fungal growth.Fórmula:C60H64Cl14MnN12O8Forma y color:SolidPeso molecular:1632.51Alteconazole
CAS:Alteconazole is an antifungal drug.Fórmula:C17H12Cl3N3OPureza:98%Forma y color:SolidPeso molecular:380.66VT-1598
CAS:VT-1598 is a novel, selective, orally active fungal CYP51 inhibitor. VT-1598 exhibits antifungal effects against Candida albicans.Fórmula:C31H20F4N6O2Forma y color:SolidPeso molecular:584.52Azaconazole
CAS:Azaconazole, an agricultural fungicide, is used for controlling powdery mildew on crops and bean rust.Fórmula:C12H11Cl2N3O2Forma y color:SolidPeso molecular:300.146-Chloro-7-deazapurine-β-D-riboside
CAS:6-Chloro-7-deazapurine-β-D-riboside shows antifungal activity.Fórmula:C11H12ClN3O4Pureza:98.26%Forma y color:SolidPeso molecular:285.68N,O-Diacetyltyramine
CAS:N,O-Diacetyltyramine, isolated from the actinomycete Pseudonocardia endophytica VUK-10, exhibits both antibacterial activity against Gram-positive and Gram-negative bacteria, alongside fungi, and demonstrates cytotoxicity towards MDA-MB-231, HeLa, MCF-7, and OAW-42 cells [1].Fórmula:C12H15NO3Forma y color:SolidPeso molecular:221.25APX001
CAS:APX001 is a prodrug of APX-001A. APX001 is the first-in-class inhibitor of the fungal protein Gwt1.Fórmula:C22H21N4O6PPureza:98%Forma y color:SolidPeso molecular:468.42-C-methylene-myo-inositol oxide
CAS:2-C-Methylene-myo-inositol oxide (NSC 45109), an inositol derivative, promotes pseudohyphal growth in Saccharomyces species [1].Fórmula:C7H12O6Forma y color:SolidPeso molecular:192.17Chitin synthase inhibitor 14
CAS:Chitin Synthase Inhibitor 14 (compound 4n), a potent chitin synthase (CHS) inhibitor, exhibits antifungal activity and is effective against drug-resistantFórmula:C25H26ClN5O5Forma y color:SolidPeso molecular:511.96Inz-1
CAS:Inz-1 is an effective and fungal-selective inhibitor of mitochondrial cytochrome bc1 with IC50s of 8.092 and 45.320 μM for yeast and human.Fórmula:C16H14N2O2Pureza:99.55% - 99.88%Forma y color:SolidPeso molecular:266.29Fenpropidin
CAS:Fenpropidin (Ro-12-3049), a fungicide, is a specific inhibitor of sterol 14-reductase and biosynthesis.Fórmula:C19H31NPureza:98.58% - 99.54%Forma y color:SolidPeso molecular:273.46Antiproliferative agent-18
CAS:Compound 5k (Antiproliferative Agent-18) is an antiproliferative agent that exhibits moderate antibacterial and antifungal activities [1].Fórmula:C26H27FN2OSForma y color:SolidPeso molecular:434.57Byssochlamic Acid
CAS:Byssochlamic acid, a mycotoxin identified in the agricultural fungal pathogen B. fulva, exhibits lethality in mice with an LD50 of 94 mg/kg.Fórmula:C18H20O6Forma y color:SolidPeso molecular:332.4MoTPS1-IN-1
CAS:MoTPS1-IN-1 is a potent MoTPS1 inhibitor with antifungal anti-inflammatory activity that acts through interaction with Glu396 study ulcerative colitis.Fórmula:C23H27F3N2O4Pureza:99.76%Forma y color:SoildPeso molecular:452.47FR194738 free base
CAS:FR194738 free base inhibits squalene epoxidase activity in HepG2 cell homogenates with an IC50 of 9.8 nM.Fórmula:C27H37NO2SPureza:99.13%Forma y color:SolidPeso molecular:439.65Ref: TM-T11321
1mg90,00€5mg170,00€10mg248,00€25mg386,00€50mg520,00€100mg672,00€1mL*10mM (DMSO)187,00€HDAC/HSP90-IN-3
CAS:HDAC/HSP90-IN-3, a dual inhibitor targeting fungal Hsp90 (IC50: 0.83 μM) & HDAC (IC50: 0.91 μM), counters azole-resistant C. albicans.Fórmula:C26H33N5O6Forma y color:SolidPeso molecular:511.57Inz-5
CAS:Inz-5 is a fungal-selective inhibitor of mitochondrial cytochrome bc1. Inz-5 impairs fungal virulence. It also prevents the evolution of drug resistance.Fórmula:C18H14F4N6Forma y color:SolidPeso molecular:390.34Zoxamide
CAS:Zoxamide (RH-7281) is an oomycete-specific fungicide that impedes nuclear division in Phytophthora capsici germlings and disrupts the microtubule cytoskeleton [Fórmula:C14H16Cl3NO2Forma y color:SolidPeso molecular:336.64APX2039
CAS:APX2039 is an orally active fungal Gwt1 enzyme inhibitor and a prodrug of the novel Gwt2096 inhibitor APX1.APX2039 exhibits potent anti-Kryptococcal activityFórmula:C20H15FN4O2Pureza:98.72% - 99.07%Forma y color:SolidPeso molecular:362.36Ref: TM-T61355
1mg123,00€5mg274,00€10mg411,00€25mg725,00€50mg1.035,00€100mg1.425,00€200mg1.882,00€1mL*10mM (DMSO)304,00€Econazole
CAS:<p>Econazole is an imidazole antifungal agent with action on fungal cell membrane disruption and is used for treating fungal skin infections like athlete's foot and ringworm.</p>Fórmula:C18H15Cl3N2OPureza:Min. 98 Area-%Forma y color:White PowderPeso molecular:381.68 g/mol2,4′-Dichloroacetanilide
CAS:2,4′-Dichloroacetanilide (2-chloro-N-(4-chlorophenyl)acetamide) has antifungal activity and inhibits T. asteroides with a MIC value of 6.25 μg/mL.Fórmula:C8H7Cl2NOPureza:99.36%Forma y color:SolidPeso molecular:204.05Fengycin
CAS:Fengycin is a cyclic lipopeptide from Bacillus subtilis acts as a biosurfactant and antifungal. As a fungicide, it has a mode of action that involves the formation of ion channels in the fungal lipid membrane, leading to membrane leakage This activity is negatively correlated to cholesterol levels, and may explain why mammalian cells, with higher cholesterol present, are not sensitive to fengycin.Fórmula:C72H110N12O20Pureza:Min. 90 Area-%Forma y color:PowderPeso molecular:1,463.71 g/molAntifungal agent 28
Antifungal 28 disrupts Candida, hits fluconazole-resistant strains, and inhibits biofilms.Fórmula:C22H29N5OSForma y color:SolidPeso molecular:411.56Antifungal agent 127
CAS:Antifungalagent 127 (Compound 6c) is an antifungal agent with potent inhibitory activity against Botrytis cinerea and Rhizoctonia solani.Fórmula:C13H12ClN3OForma y color:SolidPeso molecular:261.707CDA-IN-1
CAS:CDA-IN-1 (Compound vs#2-1) is an inhibitor of chitin deacetylase (CDA) that exhibits antifungal activity. By inhibiting fungal CDA activity, it activates plant immune responses and leads to the accumulation of reactive oxygen species (ROS), hindering fungal growth. At a concentration of 100 μM, CDA-IN-1 achieves inhibition rates of 86.9% on P. xanthii's PxCDA1 and 74.5% on PxCDA2. CDA-IN-1 is applicable in research on fungal plant diseases, such as cucumber powdery mildew and tomato gray mold.Fórmula:C15H14N2O6Forma y color:SolidPeso molecular:318.281Antifungal agent 19
Antifungal agent 19 shows the potent antifungal activity ( EC 50 = 0.72 μM).Fórmula:C19H18F4O2Forma y color:SolidPeso molecular:354.34Antifungal agent 134
CAS:Antifungalagent 134 (Compound B13) is an antifungal agent effective against Botrytis cinerea, Alternaria solani, Fusarium graminearum, Rhizoctonia solani, Colletotrichum orbiculare, and Alternaria alternata with EC50 values of 3.24, 1.89, 1.70, 0.36, 4.27, and 1.50 μg/mL, respectively. It disrupts the fungal cell membranes and mitochondria, leading to substantial accumulation of reactive oxygen species (ROS). Additionally, Antifungalagent 134 exhibits significant herbicidal activity on field weeds such as Amaranthus retroflexus L and Abutilon theophrasti Medicus, and is applicable in crop disease and field weed research.Fórmula:C18H12F4N2O4Forma y color:SolidPeso molecular:396.29HDAC-IN-87
CAS:HDAC-IN-87 (Compound XII6) is a non-selective HDAC inhibitor with pIC50 values of 6.9 for HDAC4 and 5.8 for HDAC6. It exhibits fungicidal activity against P. sorghi and P. pachyrhizi. The acute oral LD50 in both male and female rats is greater than 500 mg/kg.Fórmula:C13H7F5N4O2SForma y color:SolidPeso molecular:378.277Antifungal agent 43
Antifungal agent 43 inhibits biofilms with low toxicity to human cancer cells.Fórmula:C24H26N4Se2Forma y color:SolidPeso molecular:528.41N'-(2-Fluorophenyl)pyrazine-2-carbohydrazide
N'-(2-Fluorophenyl)pyrazine-2-carbohydrazide is a Ole1p desaturase inhibitor as well as antifungal agent [1].Fórmula:C11H9FN4OForma y color:SolidPeso molecular:232.21Pyriofenone
CAS:Pyriofenone (IKF-309) is an aryl phenyl ketone fungicide predominantly used to control powdery mildew on crops such as cereals, rice, fruit trees, and vegetables. It exhibits moderate efficacy against rice blast disease. Pyriofenone functions through prevention, residue activity, treatment, rainfastness, translaminar action, and fumigation.Fórmula:C18H20ClNO5Forma y color:SolidPeso molecular:365.81Hyalodendrin
CAS:Hyalodendrin ((+)-Hyalodendrin) acts as a fungal growth inhibitor, specifically targeting wood decay fungi. It exhibits low phytotoxicity and possesses an acute toxicity (LD50) level of 75 mg/kg in mice.Fórmula:C14H16N2O3S2Forma y color:SolidPeso molecular:324.42Antifungal agent 13
CAS:Antifungal agent 13 demonstrates significant antifungal activity against Sclerotinia sclerotiorum, achieving an EC50 of 1.25 mg/L.Fórmula:C21H16ClF3N4OForma y color:SolidPeso molecular:432.83Chitin synthase inhibitor 6
Compound 9b inhibits CHS with an IC50 of 0.21 mM; it's a broad-spectrum antifungal, effective against resistant strains.Fórmula:C24H25N3O6Forma y color:SolidPeso molecular:451.47Antifungal agent 25
Antifungal agent 25: broad-spectrum, stable in vivo, effective against Candida albicans, including fluconazole-resistant strains.Forma y color:SolidAntifungal agent 16
Antifungal agent 16 has antimicrobial activity comparable to that of ciprofloxacin and has higher antifungal activity than fluconazole.Fórmula:C27H21N5O2SForma y color:SolidPeso molecular:479.55Succinate dehydrogenase-IN-8
CAS:Succinate dehydrogenase-IN-8 (compound i19) is a potent inhibitor of succinate dehydrogenase (SDH). This indanoyl amino acid derivative demonstrates strong antifungal activity in vitro against Rhizoctonia solani (EC50 = 0.1843 mg/L), Botrytis cinerea (EC50 = 0.4829 mg/L), and Sclerotinia sclerotiorum (EC50 = 0.1349 mg/L).Fórmula:C22H19Cl2F2N5O2Forma y color:SolidPeso molecular:494.32Tenellin
CAS:Tenellin is a fungal metabolite that inhibits Mg2+-, Ca2+-, and Na+/K+-ATPase activities in erythrocytes. Tenellin is cytotoxic to Sf9 and Sf21 insect cells.Fórmula:C21H23NO5Forma y color:SolidPeso molecular:369.41Complex III-IN-1
Complex III-IN-1 inhibits complex III, has antifungal properties, and an EC50 of 18.53 mg/L against S. sclerotiorum.Fórmula:C14H20ClNO2S2Forma y color:SolidPeso molecular:333.9Yck2-IN-1
CAS:Yck2-IN-1 (Compound 2a) is an inhibitor of the fungus Candida albicans Yck2. It has an IC50 of approximately 80 nM for Yck2 and an MIC80 of 12.5 µM for C. albicans, demonstrating good metabolic stability [66% remaining in mouse liver microsomes]. In a mouse model with drug-resistant Candida, Yck2-IN-1 significantly reduced fungal load in the kidneys. Yck2-IN-1 shows potential for research in antifungal infection treatments.Fórmula:C19H11FN4Forma y color:SolidPeso molecular:314.316CDA-IN-2
CAS:CDA-IN-2 (Compound VS#2-3) is an inhibitor of chitin deacetylase (CDA) that exhibits antifungal properties. At a concentration of 100 μM, it inhibits P. xanthii's CDAPxCDA1 by 83.7% and PxCDA2 by 74.5%. CDA-IN-2 is applicable in research on agricultural fungal diseases, including resistance to powdery mildew and gray mold.Fórmula:C17H16N2O7Forma y color:SolidPeso molecular:360.318Isopyrazam
CAS:Isopyrazam, a plant protection product, exhibits potent antifungal activity. When applied to crops, it effectively inhibits the growth of various plant pathogenic fungi, significantly enhancing both the yield and quality of the crops. This compound demonstrates exceptional disease resistance capabilities in agricultural applications.Fórmula:C20H23F2N3OForma y color:SolidPeso molecular:359.41RMG8-8
RMG8-8 shows the excellent efficacy against C. neoformans (1.56 μg/mL).Fórmula:C41H78N8O5Forma y color:SolidPeso molecular:763.11Antifungal agent 12
Antifungal agent 12 is a new fluconazole-like compound that exhibits good antifungal effects.Fórmula:C20H16F3N7O2S2Forma y color:SolidPeso molecular:507.51WQ3810 TFA
WQ3810 TFA is an orally available fluoroquinolone with antimicrobial activity against Mycobacterium tuberculosis and inhibits the DNA rotamase activity ofFórmula:C24H23F6N5O5Pureza:99.52%Forma y color:SoildPeso molecular:575.46Antifungal agent 42
Antifungal 42 blocks biofilm formation and inhibits C.albicans' CYP51.Fórmula:C22H20Cl2N4Se2Forma y color:SolidPeso molecular:569.25Chitin synthase inhibitor 9
CHS inhibitor 9: a broad-spectrum antifungal for studying fungal infections.Fórmula:C24H25N3O6Forma y color:SolidPeso molecular:451.47Antifungal agent 11
Antifungal agent 11 has a good antifungal effect.Fórmula:C21H19F2N7O3S2Forma y color:SolidPeso molecular:519.55A25822B
CAS:A25822B is an antifungal agent.Fórmula:C28H45NOPureza:98%Forma y color:SolidPeso molecular:411.66AnCDA-IN-1
CAS:AnCDA-IN-1 (Compound J075-4187) is an inhibitor of chitin deacetylase (CDA) exhibiting antifungal properties. It possesses an IC50 of 4.24 μM against A. nidulans AnCDA. The compound demonstrates a minimum inhibitory concentration (MIC) of 260 μg/mL and a minimum fungicidal concentration (MFC) of 520 μg/mL for food spoilage fungi and plant pathogenic fungi. AnCDA-IN-1 is applicable for research in the antifungal domain.Fórmula:C16H13ClN4O2Forma y color:SolidPeso molecular:328.753Wikstrol A
CAS:Wikstrol A: antifungal, anti-mitotic, anti-HIV agent with various IC50/MDC values (67.8-131 µM) and deforms P. oryzae mycelia.Fórmula:C30H22O10Forma y color:SolidPeso molecular:542.49Complex III-IN-2
Complex III-IN-2 inhibits complex III, with antifungal EC50: 29.31 mg/L vs R. solani, 29.98 mg/L vs S. sclerotiorum.Fórmula:C15H21ClN2O2SForma y color:SolidPeso molecular:328.86(Z)-Lanoconazole
<p>(Z)-Lanoconazole, an imidazole antifungal for dermatophytosis and onychomycosis, inhibits fungal ergosterol production.</p>Fórmula:C14H10ClN3S2Forma y color:SolidPeso molecular:319.83Furametpyr
CAS:Furametpyr is a kind of low toxicity pesticides used to control plant diseases caused by various pathogenic microorganisms.Fórmula:C17H20ClN3O2Pureza:98%Forma y color:SolidPeso molecular:333.81Antifungal agent 40
Antifungal agent 40 blocks C. albicans CYP51 in pocket II, hindering lanosterol demethylase and biofilm growth.Fórmula:C22H20Cl2N4SeForma y color:SolidPeso molecular:490.29Antifungal agent 125
CAS:Antifungalagent 125 (compound 4H) is a potent succinate dehydrogenase (SDH) inhibitor with an IC50 of 3.59 μg/mL and exhibits fungicidal activity against Alternaria alternata.Fórmula:C13H10BrNO4SForma y color:SolidPeso molecular:356.192Chitin synthase inhibitor 11
Potent CHS inhibitor with an IC50 of 0.10 mM; exhibits broad-spectrum antifungal properties.Fórmula:C24H24N4O8Forma y color:SolidPeso molecular:496.47Chitin synthase inhibitor 5
Calpain Inhibitor-2, lipophilic, inhibits calpain; shows anti-proliferative effects on melanoma, PC-3 cells; blocks 80% DU-145 cell invasion.Fórmula:C23H22BrN3O5Forma y color:SolidPeso molecular:500.34Chitin synthase inhibitor 8
Chitin synthase inhibitor 8 is a chitin synthase (CHS) inhibitor with broad-spectrum antifungal effects that can be used in studies related to fungal infectionsFórmula:C23H23N3O5Forma y color:SolidPeso molecular:421.45Fosmanogepix
CAS:Fosmanogepix (APX001) is a broad-spectrum oral antifungal that targets Gwt1 enzyme, transforming into active APX001A in the body.Fórmula:C22H21N4O6PPureza:98%Forma y color:SolidPeso molecular:468.40bc1 Complex-IN-1
CAS:Bc1 Complex-IN-1 (compound 12g) is a potent inhibitor of the bc1 complex, demonstrating fungicidal properties against cucumber downy mildew (CDM).Fórmula:C16H22N6O5S2Forma y color:SolidPeso molecular:442.513Antifungal agent 100
CAS:Antifungal agent 100 (compound 3i) demonstrates notable antifungal activity, exhibiting an EC 50 of 0.33 mg/L against S. sclerotiorum. It also possesses an IC 50 value of 0.63 mg/mL targeting the Succinate dehydrogenase (SDH) of the same organism [1].Fórmula:C23H21N3O4SForma y color:SolidPeso molecular:435.5Chitin synthase inhibitor 12
Chitin synthase inhibitor 12: potent CHS blocker (IC50: 0.16 mM), broad-spectrum antifungal, effective against resistant strains. Useful in IFI research.Fórmula:C23H21ClFN3O5Forma y color:SolidPeso molecular:473.88ATPase-IN-5
CAS:<p>ATPase-IN-5 (Compound 11) is an antifungal Pma1p (H+ -ATPase) inhibitor (IC50 = 12.7 μM) that inhibits the growth of Candida albicans and Saccharomyces cerevisiae.</p>Fórmula:C10H10N4O3SPureza:99.19%Forma y color:SolidPeso molecular:266.28Ref: TM-T204943
1mg185,00€5mg459,00€10mg657,00€25mg1.026,00€50mg1.415,00€100mg1.872,00€200mg2.555,00€Chitin synthase inhibitor 7
Compound 9c, a chitin synthase inhibitor, has an IC50 of 0.37 nM and is useful for studying fungal infections.Fórmula:C24H25N3O5Forma y color:SolidPeso molecular:435.47CYP51-IN-7
CAS:CYP51-IN-7 (compound 1g) is an analogue of Fluconazole and serves as an effective antifungal agent. It exhibits inhibitory activity against Microsporum gypseum and Candida albicans, with MIC80 values of 62.5 ng/mL and 250 ng/mL, respectively.Fórmula:C21H21ClF2N4OPeso molecular:418.87GW461484A
CAS:GW461484A is a small molecule inhibitor targeting Candida albicans Yck2, exhibiting an IC50 of 0.11 µM. It has a MIC80 of 12.5 µM against C. albicans. GW461484A shows potential for research into fungal diseases, including drug-resistant Candida infections.Fórmula:C19H14FN3Forma y color:SolidPeso molecular:303.333Benzohydroxamic acid
CAS:Benzohydroxamic acid (BHA) is a chitin deacetylase (CDA) inhibitor with notable antifungal properties. It displays Ki values of 8.31 μM against Verticillium dahliae CDA and 9.83 μM against Puccinia striiformis f. sp. tritici CDA. BHA can restore the defense responses in infected host plants by upregulating the expression of defense-related genes, thereby reducing fungal growth and proliferation within the plants. It is applicable in the research of agricultural fungal diseases, such as cotton wilt and wheat stripe rust, caused by pathogens like Verticillium dahliae and Puccinia striiformis.Fórmula:C7H7NO2Forma y color:SolidPeso molecular:137.136FDU-PB-22
CAS:FDU-PB-22, a novel synthetic cannabinoid, undergoes rapid metabolism in human liver microsomes (HLM) with a half-life of 12.4 minutes.Fórmula:C26H18FNO2Forma y color:SolidPeso molecular:395.43EGFR-IN-133
CAS:EGFR-IN-133 (Compound 24) serves as an inhibitor targeting various mutations of the EGFR, including the wild type, L858R/T790M, d19/T790M, L858R/T790M/C797S, and d19/T790M/C797S with respective IC50 values of 0.1, 0.044, 0.036, 0.04, and 0.054 nM. The compound exhibits favorable pharmacokinetic properties and high oral bioavailability.Fórmula:C27H29F2N7O3Forma y color:SolidPeso molecular:537.56SDH-IN-25
CAS:<p>SDH-IN-25 is an SDH inhibitor with an IC50 of 4.82 mg/L, demonstrating broad-spectrum and potent antifungal activity. By binding to SDH amino acid residues (TRP173, TYR58, and ARG43), it mimics the action mode of the commercial fungicide flutolanil. SDH-IN-25 induces changes in hyphal morphology, disrupts respiratory metabolism by binding to complex II, generates reactive oxygen species (ROS), and affects mitochondrial membrane potential (MMP) in hyphae. This compound is utilized in agricultural disease control research.</p>Fórmula:C19H15BrCl2N2O4Forma y color:SolidPeso molecular:486.143(3R,6S)-Bassiatin
CAS:(3R,6S)-Bassiatin represents the enantiomeric form of the fungal metabolite known as bassiatin.Fórmula:C15H19NO3Peso molecular:261.32Antifungal agent 17
Antifungal agent 17 showed good antifungal activity against B. cinerea (EC50: 2.86 μg/mL).Fórmula:C18H16Br2O2Forma y color:SolidPeso molecular:424.13Ethaboxam
CAS:Ethaboxam is a β-tubulin inhibitor and antifungal agent used against oomycete pathogens.Fórmula:C14H16N4OS2Pureza:99.37%Forma y color:SolidPeso molecular:320.43Ref: TM-T204712
1mg185,00€5mg459,00€10mg657,00€25mg1.026,00€50mg1.415,00€100mg1.872,00€200mg2.555,00€CYP51-IN-14
CAS:CYP51-IN-14 (compound 1n), a derivative of Fluconazole, functions as an effective antifungal agent. This compound inhibits Microsporum gypseum and Candida albicans with a minimum inhibitory concentration (MIC80) of 1 μg/mL.Fórmula:C21H20Cl2F2N4OPeso molecular:453.31HSP90-IN-9
HSP90-IN-9: potent HSP90 inhibitor, dose-dependent fungicide, impedes biofilm/morphology with FLC, reverses FLC resistance.Forma y color:SolidVNI
CAS:VNI is an effective inhibitor of CYP51. It suppresses sterol synthesis in Trypanosoma cruzi, exhibiting anti-Trypanosoma cruzi activity.Fórmula:C26H19Cl2N5O2Forma y color:SolidPeso molecular:504.37Griseofulvic Acid
CAS:Griseofulvic Acid ((±)-Griseofulvic acid) is a metabolite of the antifungal agent Griseofulvin. It induces protein aggregation and tubulin polymerization in cell-free assays.Fórmula:C16H15ClO6Peso molecular:338.74Antibacterial agent 188
CAS:Compound 2d (Antibacterial agent 188) serves as an antibacterial agent that suppresses the activity of dermatophytes [1].Fórmula:C12H10N4SForma y color:SolidPeso molecular:242.3CDA-IN-3
CAS:CDA-IN-3 (NCDI) is a chitin deacetylase (CDA) inhibitor with antiparasitic properties. It disrupts chitin metabolism in nematodes, increasing ROS levels within these organisms and causing cellular damage. CDA-IN-3 significantly inhibits all developmental stages of Caenorhabditis elegans and can be utilized in research focused on anti-infective applications.Fórmula:C16H27N3O3S2Forma y color:SolidPeso molecular:373.534Antifungal agent 39
CAS:Antifungal agent 39 (Compound 9h) is a broad-spectrum antifungal agent.Fórmula:C23H22ClN3O5Forma y color:SolidPeso molecular:455.89CDA-IN-4
CAS:CDA-IN-4 (compound VS-24) is an inhibitor of chitin deacetylase (CDA). At a concentration of 100 μg/mL, CDA-IN-4 provides a protective effect of 61.2% against rice blast disease.Fórmula:C10H9BrN4O2SForma y color:SolidPeso molecular:329.17PKR-IN-1
CAS:PKR-IN-1 (Compound 5s) is a pyruvate kinase (PK) inhibitor with antifungal properties, exhibiting an EC50 of 0.21 μg/mL against Rhizoctonia solani (R. solani).Fórmula:C9HCl5N4OS2Forma y color:SolidPeso molecular:422.525SARS-CoV-2 Mpro-IN-34
SARS-CoV-2 Mpro-IN-34 (Compound 26) acts as an inhibitor of SARS-CoV-2 Mpro with an IC50 of 6 nM. It also inhibits OC43 Mpro, demonstrating an IC50 of 33 nM. Furthermore, this compound exhibits antiviral activity in Vero E6 cells infected with SARS-CoV-2, with an EC50 of 0.103 μM.Fórmula:C30H37Cl2N5O3Forma y color:SolidPeso molecular:586.55Nikkomycin Z
CAS:Nikkomycin Z (Nikkomycin Z from Streptomyces tendae) is a competitive chitin synthase inhibitor.It inhibitor of the growth of filamentous fungi, insects,Fórmula:C20H25N5O10Pureza:98%Forma y color:SolidPeso molecular:495.44D75-4590
CAS:<p>D75-4590, a β-1,6-Glucan synthetase inhibitor, combats fungal infections by targeting cell walls.</p>Fórmula:C21H27N5Pureza:98.56% - 98.85%Forma y color:SolidPeso molecular:349.474-Hydroxyvoriconazole
CAS:<p>Metabolite of voriconazole; sterol 14?-demethylase inhibitor</p>Pureza:Min. 95%2,7-Dihydroxynaphthalene
CAS:2,7-Dihydroxynaphthalene is a useful organic compound for research related to life sciences. The catalog number is T67338 and the CAS number is 582-17-2.Fórmula:C10H8O2Forma y color:SolidPeso molecular:160.17Tetraconazole
CAS:Tetraconazole is an agent of pesticides.Fórmula:C13H11Cl2F4N3OForma y color:Liquid ViscousPeso molecular:372.14Rhizocticin A
CAS:Rhizocticin A is a potential inhibitor of threonine synthase.Fórmula:C11H22N5O6PPureza:98%Forma y color:SolidPeso molecular:351.3Amphotericin A
CAS:<p>Amphotericin A is a polyene macrolide antibiotic, which is derived primarily from the soil bacterium *Streptomyces nodosus*. This compound functions by binding to ergosterol, an essential component of fungal cell membranes. This binding creates pores in the membrane, increasing its permeability and ultimately leading to cell death. Unlike its more widely used counterpart Amphotericin B, Amphotericin A is less frequently utilized but is critical in the study and understanding of antifungal activity.</p>Fórmula:C47H75NO17Pureza:Min. 95%Peso molecular:926.09 g/mol1-(6-Amino-3,5-difluoro-2-pyridinyl)-7-[3-[3-[[1-(6-amino-3,5-difluoro-2-pyridinyl)-3-carboxy-8-chloro-6-fluoro-1,4-dihydro-4-oxo-7- quinolinyl]amino]-2-hydroxypropoxy]-1-azetidinyl]-8-chloro-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
CAS:<p>1-(6-Amino-3,5-difluoro-2-pyridinyl)-7-[3-[3-[[1-(6-amino-3,5-difluoro-2-pyridinyl)-3-carboxy-8-chloro-6-fluoro-1,4-dihydro-4-oxo-7-quinolinyl]amino]-2-hydroxypropoxy]-1-azetidinyl]-8-chloro-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid is a fluoroquinolone antibiotic, engineered through synthetic chemistry. It is derived from chemical sources involving complex organic synthesis, highlighting its intricate molecular architecture. Its mode of action is distinctive, as it inhibits bacterial DNA gyrase and topoisomerase IV, enzymes crucial for DNA replication and transcription. This interference with bacterial DNA processes results in bactericidal effects, effectively eliminating susceptible bacterial strains.</p>Fórmula:C36H24Cl2F6N8O8Pureza:Min. 95%Peso molecular:881.52 g/molRef: 3D-AA184076
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