Antifúngicos
Los antifúngicos son compuestos específicamente diseñados para detener, prevenir y eliminar el crecimiento de hongos. En esta categoría, encontrará una amplia variedad de agentes antifúngicos esenciales para aplicaciones de investigación y terapéuticas. Estos compuestos son cruciales en el tratamiento de infecciones fúngicas y en la prevención de su recurrencia, lo que los convierte en herramientas vitales tanto en entornos médicos como agrícolas. Investigadores y profesionales de la salud pueden explorar numerosos antifúngicos para comprender sus mecanismos, optimizar su eficacia y desarrollar nuevos tratamientos para combatir cepas de hongos resistentes. La extensa selección de antifúngicos respalda los avances continuos en la investigación fúngica y el desarrollo de terapias antifúngicas efectivas.
Se han encontrado 939 productos de "Antifúngicos"
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CDA-IN-4
CAS:CDA-IN-4 (compound VS-24) is an inhibitor of chitin deacetylase (CDA). At a concentration of 100 μg/mL, CDA-IN-4 provides a protective effect of 61.2% against rice blast disease.Fórmula:C10H9BrN4O2SForma y color:SolidPeso molecular:329.17CDA-IN-3
CAS:CDA-IN-3 (NCDI) is a chitin deacetylase (CDA) inhibitor with antiparasitic properties. It disrupts chitin metabolism in nematodes, increasing ROS levels within these organisms and causing cellular damage. CDA-IN-3 significantly inhibits all developmental stages of Caenorhabditis elegans and can be utilized in research focused on anti-infective applications.Fórmula:C16H27N3O3S2Forma y color:SolidPeso molecular:373.534Antifungal agent 17
Antifungal agent 17 showed good antifungal activity against B. cinerea (EC50: 2.86 μg/mL).Fórmula:C18H16Br2O2Forma y color:SolidPeso molecular:424.13SDH-IN-25
CAS:SDH-IN-25 is an SDH inhibitor with an IC50 of 4.82 mg/L, demonstrating broad-spectrum and potent antifungal activity. By binding to SDH amino acid residues (TRP173, TYR58, and ARG43), it mimics the action mode of the commercial fungicide flutolanil. SDH-IN-25 induces changes in hyphal morphology, disrupts respiratory metabolism by binding to complex II, generates reactive oxygen species (ROS), and affects mitochondrial membrane potential (MMP) in hyphae. This compound is utilized in agricultural disease control research.Fórmula:C19H15BrCl2N2O4Forma y color:SolidPeso molecular:486.143Chitin synthase inhibitor 12
Chitin synthase inhibitor 12: potent CHS blocker (IC50: 0.16 mM), broad-spectrum antifungal, effective against resistant strains. Useful in IFI research.Fórmula:C23H21ClFN3O5Forma y color:SolidPeso molecular:473.88ATPase-IN-5
CAS:ATPase-IN-5 (Compound 11) is an antifungal Pma1p (H+ -ATPase) inhibitor (IC50 = 12.7 μM) that inhibits the growth of Candida albicans and Saccharomyces cerevisiae.Fórmula:C10H10N4O3SPureza:99.19%Forma y color:SolidPeso molecular:266.28Chitin synthase inhibitor 7
Compound 9c, a chitin synthase inhibitor, has an IC50 of 0.37 nM and is useful for studying fungal infections.Fórmula:C24H25N3O5Forma y color:SolidPeso molecular:435.47Ethaboxam
CAS:Ethaboxam is a β-tubulin inhibitor and antifungal agent used against oomycete pathogens.Fórmula:C14H16N4OS2Pureza:99.37%Forma y color:SolidPeso molecular:320.43HDAC-IN-87
CAS:HDAC-IN-87 (Compound XII6) is a non-selective HDAC inhibitor with pIC50 values of 6.9 for HDAC4 and 5.8 for HDAC6. It exhibits fungicidal activity against P. sorghi and P. pachyrhizi. The acute oral LD50 in both male and female rats is greater than 500 mg/kg.Fórmula:C13H7F5N4O2SForma y color:SolidPeso molecular:378.277Chitin synthase inhibitor 6
Compound 9b inhibits CHS with an IC50 of 0.21 mM; it's a broad-spectrum antifungal, effective against resistant strains.Fórmula:C24H25N3O6Forma y color:SolidPeso molecular:451.47D75-4590
CAS:D75-4590, a β-1,6-Glucan synthetase inhibitor, combats fungal infections by targeting cell walls.Fórmula:C21H27N5Pureza:98.56% - 98.85%Forma y color:SolidPeso molecular:349.47Ref: TM-T61194
5mg39,00€1mL*10mM (DMSO)46,00€10mg62,00€25mg122,00€50mg187,00€100mg269,00€200mg358,00€4-Hydroxyvoriconazole
CAS:Metabolite of voriconazole; sterol 14?-demethylase inhibitorPureza:Min. 95%1H-1,2,4-Triazole-1-ethanol, α-(2,4-difluorophenyl)-α-(1H-1,2,4-triazol-1-ylmethyl)-
CAS:Fórmula:C13H12F2N6OPureza:98%Forma y color:SolidPeso molecular:306.2708Fumifungin
CAS:Fumifungin is a useful organic compound for research related to life sciences. The catalog number is T126406 and the CAS number is 110231-33-9.Fórmula:C22H41NO7Forma y color:SolidPeso molecular:431.572,7-Dihydroxynaphthalene
CAS:2,7-Dihydroxynaphthalene is a useful organic compound for research related to life sciences. The catalog number is T67338 and the CAS number is 582-17-2.Fórmula:C10H8O2Forma y color:SolidPeso molecular:160.17Pam2CSK4 TFA
Pam2CSK4 TFA (PUL-042 TFA) is a potent dual agonist of TLR2 and TLR6, a peptide that mimics bacterial lipoproteins.Pam2CSK4 TFA promotes platelet aggregation, and can be used to study the effects of lipoproteins on the periodontium.Fórmula:C67H127F3N10O14SPureza:99.90%Forma y color:SoildPeso molecular:1385.84Rhizocticin A
CAS:Rhizocticin A is a potential inhibitor of threonine synthase.Fórmula:C11H22N5O6PPureza:98%Forma y color:SolidPeso molecular:351.3Tetraconazole
CAS:Tetraconazole is an agent of pesticides.Fórmula:C13H11Cl2F4N3OForma y color:Liquid ViscousPeso molecular:372.14Amphotericin A
CAS:Amphotericin A is a polyene macrolide antibiotic, which is derived primarily from the soil bacterium *Streptomyces nodosus*. This compound functions by binding to ergosterol, an essential component of fungal cell membranes. This binding creates pores in the membrane, increasing its permeability and ultimately leading to cell death. Unlike its more widely used counterpart Amphotericin B, Amphotericin A is less frequently utilized but is critical in the study and understanding of antifungal activity.
Fórmula:C47H75NO17Pureza:Min. 95%Peso molecular:926.09 g/mol
