Antimicrobianos

Enoxacin is a fluoroquinolone antibiotic with action on bacterial DNA gyrase and topoisomerase IV and is used for treating urinary tract infections and gonorrhea.

Oritavancin diphosphate is a lipoglycopeptide antibiotic with action on bacterial cell wall synthesis and is used for treating acute bacterial skin and skin structure infections.

Doramectin is a macrocyclic lactone antiparasitic agent with action on glutamate-gated chloride channels in parasites and is used for treating internal and external parasitic infections in livestock.

Dihydrostreptomycin B is an aminoglycoside antibiotic, which is derived from the bacterium Streptomyces griseus. This antibiotic operates by binding to the 30S subunit of the bacterial ribosome, leading to the inhibition of protein synthesis. The binding disrupts the decoding site, causing misreading of mRNA and ultimately resulting in bactericidal activity.

Closantel sodium dihydrate is a salicylanilide antiparasitic agent with action on flukes, nematodes, and arthropods and is used for veterinary treatment of parasitic infections.

Butoconazole nitrate is an antifungal agent and is used for the treatment of vaginal yeast infections. It inhibits the synthesis of ergosterol, disrupting the fungal cell membrane.

Tenofovir diphosphate triethylamine (mixture of diastereomers) is an antiviral compound, which is a synthetic chemical product derived from the parent compound, tenofovir. This formulation includes a mixture of diastereomers to enhance its solubility and bioavailability. The compound primarily functions as a nucleotide reverse transcriptase inhibitor (NRTI). It targets viral reverse transcriptase enzymes, inhibiting DNA synthesis and subsequent viral replication by causing premature chain termination.

Albomitomycin A is an antibiotic compound, which is derived from the fermentation of specific Streptomyces species. This compound exhibits a unique mode of action by inhibiting protein synthesis in bacterial cells, specifically targeting the 30S ribosomal subunit. This interference with ribosomal function ultimately disrupts the production of essential proteins, leading to bacterial cell death.

Emtricitabine is a nucleoside analog that is an antiviral drug used to treat HIV/AIDS. It is a synthetic nucleoside analog of cytidine, in which the 3' phosphate and 5' hydroxyl groups have been replaced with a fluorine atom and a methoxy group, respectively. Emtricitabine has been shown to inhibit the synthesis of viral DNA by competing for incorporation into the viral DNA strand during the elongation phase of viral replication. Emtricitabine also has anticancer activity, but no other known therapeutic uses.

Erythromycin thiocyanate is a macrolide antibiotic derivative with action on bacterial protein synthesis inhibition and is used for research and pharmaceutical applications.

Cefditoren pivoxil is a third-generation cephalosporin antibiotic with action on bacterial cell wall synthesis and is used for treating respiratory and skin infections.

Enrofloxacin is a rapidly bactericidal antibiotic, that inhibits bacterial growth by binding to the 50S ribosomal subunit and blocking protein synthesis, thereby preventing the bacteria from making new proteins. Enrofloxacin also has strong activity against gram-positive bacteria, including Clostridium perfringens which is an anaerobic bacterium that causes food-borne illness. This antibiotic is used for the treatment of acute bacterial infections in humans, such as, skin or soft tissue infections, urinary tract infections (UTIs) and septicemia (bloodstream infection). Enrofloxacin has shown excellent bioavailability with high serum protein binding capacity. Additionally, it has good efficacy against clinical isolates of Escherichia coli and Klebsiella pneumoniae. Enrofloxacin can be used effective in treatments for Pseudomonas aeruginosa and Enterobacter species.

Inhibitor of cell wall synthesis; cephalosporin class

Butenafine hydrochloride is a mycological agent that is used to treat tinea. It has been shown to have an antifungal activity in vitro against wild-type strains of c. glabrata. Butenafine hydrochloride inhibits the synthesis of ergosterol, which is a vital component of fungal cell membranes, by blocking the conversion of squalene to lanosterol through inhibition of 14alpha-demethylase. It also has antimicrobial properties, which may be due to its ability to inhibit bacterial growth.

Capastat sulfate is an antibiotic with action against Mycobacterium tuberculosis by inhibiting protein synthesis and is used for treating tuberculosis.

PS 3061 is a type of biostimulant, which is derived from activated charcoal. Activated charcoal serves as the source of this biostimulant, providing a unique substrate that interacts with soil and plant roots. Its mode of action involves enhancing nutrient uptake and improving soil microbial activity, thereby facilitating better plant growth and development.